Motif ID: ELF3_EHF

Z-value: 0.785

Transcription factors associated with ELF3_EHF:

Gene SymbolEntrez IDGene Name
EHF ENSG00000135373.8 EHF
ELF3 ENSG00000163435.11 ELF3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
EHFhg19_v2_chr11_+_34643600_346437500.791.1e-02Click!
ELF3hg19_v2_chr1_+_201979645_201979721-0.781.3e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of ELF3_EHF

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_100842588 2.204 ENST00000556645.1
ENST00000556209.1
ENST00000556504.1
ENST00000556435.1
ENST00000554772.1
ENST00000553581.1
ENST00000553769.2
ENST00000554605.1
ENST00000557722.1
ENST00000553413.1
ENST00000553524.1
ENST00000358655.4
WARS











tryptophanyl-tRNA synthetase











chr9_+_100174344 1.646 ENST00000422139.2
TDRD7
tudor domain containing 7
chr7_-_944631 1.375 ENST00000453175.2
ADAP1
ArfGAP with dual PH domains 1
chr5_-_131826457 1.364 ENST00000437654.1
ENST00000245414.4
IRF1

interferon regulatory factor 1

chr1_+_213224572 1.138 ENST00000543470.1
ENST00000366960.3
ENST00000366959.3
ENST00000543354.1
RPS6KC1



ribosomal protein S6 kinase, 52kDa, polypeptide 1



chr1_-_183560011 1.113 ENST00000367536.1
NCF2
neutrophil cytosolic factor 2
chr15_+_45879534 1.031 ENST00000562384.1
ENST00000569076.1
ENST00000566753.1
ENST00000564080.1
BLOC1S6


RP11-96O20.4
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin


Uncharacterized protein
chr12_+_113344811 0.885 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
OAS1


2'-5'-oligoadenylate synthetase 1, 40/46kDa


chr20_-_48532019 0.835 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr20_-_48532046 0.828 ENST00000543716.1
SPATA2
spermatogenesis associated 2
chr11_+_2421718 0.782 ENST00000380996.5
ENST00000333256.6
ENST00000380992.1
ENST00000437110.1
ENST00000435795.1
TSSC4




tumor suppressing subtransferable candidate 4




chr3_+_52321827 0.771 ENST00000473032.1
ENST00000305690.8
ENST00000354773.4
ENST00000471180.1
ENST00000436784.2
GLYCTK




glycerate kinase




chr12_+_113344755 0.746 ENST00000550883.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr10_+_91061712 0.745 ENST00000371826.3
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr14_+_100842735 0.744 ENST00000554998.1
ENST00000402312.3
ENST00000335290.6
ENST00000554175.1
WDR25



WD repeat domain 25



chr12_-_123201337 0.701 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr12_+_10331605 0.700 ENST00000298530.3
TMEM52B
transmembrane protein 52B
chr12_-_123187890 0.670 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr19_-_56632592 0.550 ENST00000587279.1
ENST00000270459.3
ZNF787

zinc finger protein 787

chr16_+_31085714 0.548 ENST00000300850.5
ENST00000564189.1
ENST00000428260.1
ZNF646


zinc finger protein 646


chr12_+_113344582 0.543 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
OAS1


2'-5'-oligoadenylate synthetase 1, 40/46kDa


chr16_-_30366672 0.533 ENST00000305596.3
CD2BP2
CD2 (cytoplasmic tail) binding protein 2
chr1_-_95285764 0.533 ENST00000414374.1
ENST00000421997.1
ENST00000418366.2
ENST00000452922.1
LINC01057



long intergenic non-protein coding RNA 1057



chr7_-_45018686 0.491 ENST00000258787.7
MYO1G
myosin IG
chr17_+_32582293 0.484 ENST00000580907.1
ENST00000225831.4
CCL2

chemokine (C-C motif) ligand 2

chr6_-_11779014 0.483 ENST00000229583.5
ADTRP
androgen-dependent TFPI-regulating protein
chr2_-_75788038 0.482 ENST00000393913.3
ENST00000410113.1
EVA1A

eva-1 homolog A (C. elegans)

chr12_+_104324112 0.478 ENST00000299767.5
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr1_-_157108130 0.473 ENST00000368192.4
ETV3
ets variant 3
chr11_+_34642656 0.464 ENST00000257831.3
ENST00000450654.2
EHF

ets homologous factor

chr12_-_53343560 0.459 ENST00000548998.1
KRT8
keratin 8
chr1_+_154975258 0.453 ENST00000417934.2
ZBTB7B
zinc finger and BTB domain containing 7B
chr11_+_35211429 0.448 ENST00000525688.1
ENST00000278385.6
ENST00000533222.1
CD44


CD44 molecule (Indian blood group)


chr1_-_157108266 0.440 ENST00000326786.4
ETV3
ets variant 3
chr8_+_182368 0.437 ENST00000522866.1
ENST00000398612.1
ZNF596

zinc finger protein 596

chr17_+_38673270 0.431 ENST00000578280.1
RP5-1028K7.2
RP5-1028K7.2
chr2_+_113342011 0.421 ENST00000324913.5
CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr1_+_32042131 0.418 ENST00000271064.7
ENST00000537531.1
TINAGL1

tubulointerstitial nephritis antigen-like 1

chr12_+_75874984 0.405 ENST00000550491.1
GLIPR1
GLI pathogenesis-related 1
chr11_+_123325106 0.403 ENST00000525757.1
LINC01059
long intergenic non-protein coding RNA 1059
chr12_+_76653611 0.397 ENST00000550380.1
RP11-54A9.1
RP11-54A9.1
chr1_+_32042105 0.393 ENST00000457433.2
ENST00000441210.2
TINAGL1

tubulointerstitial nephritis antigen-like 1

chr15_+_59903975 0.393 ENST00000560585.1
ENST00000396065.1
GCNT3

glucosaminyl (N-acetyl) transferase 3, mucin type

chr6_+_126240442 0.388 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7


nuclear receptor coactivator 7


chr1_-_43637915 0.388 ENST00000236051.2
EBNA1BP2
EBNA1 binding protein 2
chr15_-_74284613 0.387 ENST00000316911.6
ENST00000564777.1
ENST00000566081.1
ENST00000316900.5
STOML1



stomatin (EPB72)-like 1



chr19_+_12780512 0.380 ENST00000242796.4
WDR83
WD repeat domain 83
chr22_+_50312379 0.374 ENST00000407217.3
ENST00000403427.3
CRELD2

cysteine-rich with EGF-like domains 2

chr21_+_43919710 0.371 ENST00000398341.3
SLC37A1
solute carrier family 37 (glucose-6-phosphate transporter), member 1
chr1_-_43638168 0.370 ENST00000431635.2
EBNA1BP2
EBNA1 binding protein 2
chr22_+_50312316 0.368 ENST00000328268.4
CRELD2
cysteine-rich with EGF-like domains 2
chr22_+_50312274 0.367 ENST00000404488.3
CRELD2
cysteine-rich with EGF-like domains 2
chr16_-_31085514 0.363 ENST00000300849.4
ZNF668
zinc finger protein 668
chr17_+_38375528 0.362 ENST00000583268.1
WIPF2
WAS/WASL interacting protein family, member 2
chr12_+_27397166 0.361 ENST00000545470.1
ENST00000540996.1
ENST00000539577.1
STK38L


serine/threonine kinase 38 like


chr3_+_47324424 0.360 ENST00000437353.1
ENST00000232766.5
ENST00000455924.2
KLHL18


kelch-like family member 18


chr11_+_576494 0.357 ENST00000533464.1
ENST00000413872.2
ENST00000416188.2
PHRF1


PHD and ring finger domains 1


chr19_-_1174226 0.355 ENST00000587024.1
ENST00000361757.3
SBNO2

strawberry notch homolog 2 (Drosophila)

chr1_+_154975110 0.354 ENST00000535420.1
ENST00000368426.3
ZBTB7B

zinc finger and BTB domain containing 7B

chr11_+_82904858 0.349 ENST00000260047.6
ANKRD42
ankyrin repeat domain 42
chr17_-_79269067 0.349 ENST00000288439.5
ENST00000374759.3
SLC38A10

solute carrier family 38, member 10

chr11_-_64885111 0.347 ENST00000528598.1
ENST00000310597.4
ZNHIT2

zinc finger, HIT-type containing 2

chr19_-_8579030 0.344 ENST00000255616.8
ENST00000393927.4
ZNF414

zinc finger protein 414

chr18_-_33077556 0.344 ENST00000589273.1
ENST00000586489.1
INO80C

INO80 complex subunit C

chr20_+_48429356 0.338 ENST00000361573.2
ENST00000541138.1
ENST00000539601.1
SLC9A8


solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8


chr1_+_31883048 0.336 ENST00000536859.1
SERINC2
serine incorporator 2
chr17_-_38256973 0.335 ENST00000246672.3
NR1D1
nuclear receptor subfamily 1, group D, member 1
chr16_+_4666475 0.319 ENST00000591895.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr5_+_180650271 0.317 ENST00000351937.5
ENST00000315073.5
TRIM41

tripartite motif containing 41

chr6_-_11779403 0.316 ENST00000414691.3
ADTRP
androgen-dependent TFPI-regulating protein
chr12_+_6561190 0.313 ENST00000544021.1
ENST00000266556.7
TAPBPL

TAP binding protein-like

chr18_-_33077942 0.312 ENST00000334598.7
INO80C
INO80 complex subunit C
chr15_+_90744533 0.305 ENST00000411539.2
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr1_+_158975744 0.302 ENST00000426592.2
IFI16
interferon, gamma-inducible protein 16
chr20_+_43104541 0.299 ENST00000372906.2
ENST00000456317.1
TTPAL

tocopherol (alpha) transfer protein-like

chr14_+_23341513 0.295 ENST00000546834.1
LRP10
low density lipoprotein receptor-related protein 10
chr19_-_55791431 0.294 ENST00000593263.1
ENST00000376343.3
HSPBP1

HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1

chr19_-_55791058 0.294 ENST00000587959.1
ENST00000585927.1
ENST00000587922.1
ENST00000585698.1
HSPBP1



HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1



chr8_-_27168737 0.293 ENST00000521253.1
ENST00000305364.4
TRIM35

tripartite motif containing 35

chr12_+_76653682 0.291 ENST00000553247.1
RP11-54A9.1
RP11-54A9.1
chr18_-_33077868 0.291 ENST00000590757.1
ENST00000592173.1
ENST00000441607.2
ENST00000587450.1
ENST00000589258.1
INO80C



RP11-322E11.6
INO80 complex subunit C



Uncharacterized protein
chr6_-_109761707 0.291 ENST00000520723.1
ENST00000518648.1
ENST00000417394.2
PPIL6


peptidylprolyl isomerase (cyclophilin)-like 6


chr17_+_4843352 0.288 ENST00000573404.1
ENST00000576452.1
RNF167

ring finger protein 167

chr3_+_159557637 0.287 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr16_+_30710462 0.287 ENST00000262518.4
ENST00000395059.2
ENST00000344771.4
SRCAP


Snf2-related CREBBP activator protein


chr19_+_52772832 0.285 ENST00000593703.1
ENST00000601711.1
ENST00000599581.1
ZNF766


zinc finger protein 766


chr14_-_74416829 0.282 ENST00000534936.1
FAM161B
family with sequence similarity 161, member B
chr19_+_19496728 0.279 ENST00000537887.1
ENST00000417582.2
GATAD2A

GATA zinc finger domain containing 2A

chr16_+_78133536 0.278 ENST00000402655.2
ENST00000406884.2
ENST00000539474.2
ENST00000569818.1
ENST00000355860.3
ENST00000408984.3
WWOX





WW domain containing oxidoreductase





chr18_-_21166841 0.277 ENST00000269228.5
NPC1
Niemann-Pick disease, type C1
chr11_+_86502085 0.276 ENST00000527521.1
PRSS23
protease, serine, 23
chr19_+_41770269 0.275 ENST00000378215.4
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr19_+_52772821 0.274 ENST00000439461.1
ZNF766
zinc finger protein 766
chr11_-_119993979 0.273 ENST00000524816.3
ENST00000525327.1
TRIM29

tripartite motif containing 29

chr17_+_4843594 0.273 ENST00000570328.1
RNF167
ring finger protein 167
chr6_-_11779174 0.271 ENST00000379413.2
ADTRP
androgen-dependent TFPI-regulating protein
chr10_+_69865866 0.271 ENST00000354393.2
MYPN
myopalladin
chr5_+_150040403 0.267 ENST00000517768.1
ENST00000297130.4
MYOZ3

myozenin 3

chr22_+_38082330 0.266 ENST00000359114.4
NOL12
nucleolar protein 12
chr11_+_123396307 0.266 ENST00000456860.2
GRAMD1B
GRAM domain containing 1B
chr19_+_55999916 0.262 ENST00000587166.1
ENST00000389623.6
SSC5D

scavenger receptor cysteine rich domain containing (5 domains)

chr11_+_576457 0.262 ENST00000264555.5
PHRF1
PHD and ring finger domains 1
chr1_+_156698743 0.261 ENST00000524343.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr11_+_65383227 0.261 ENST00000355703.3
PCNXL3
pecanex-like 3 (Drosophila)
chr19_-_6393216 0.260 ENST00000595047.1
GTF2F1
general transcription factor IIF, polypeptide 1, 74kDa
chr1_+_43637996 0.258 ENST00000528956.1
ENST00000529956.1
WDR65

WD repeat domain 65

chr5_-_138861926 0.255 ENST00000510817.1
TMEM173
transmembrane protein 173
chr22_-_24181174 0.253 ENST00000318109.7
ENST00000406855.3
ENST00000404056.1
ENST00000476077.1
DERL3



derlin 3



chr1_+_44435646 0.251 ENST00000255108.3
ENST00000412950.2
ENST00000396758.2
DPH2


DPH2 homolog (S. cerevisiae)


chr1_-_154946792 0.250 ENST00000412170.1
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr5_+_149737202 0.248 ENST00000451292.1
ENST00000377797.3
ENST00000445265.2
ENST00000323668.7
ENST00000439160.2
ENST00000394269.3
ENST00000427724.2
ENST00000504761.2
ENST00000513346.1
ENST00000515516.1
TCOF1









Treacher Collins-Franceschetti syndrome 1









chr12_+_44152740 0.248 ENST00000440781.2
ENST00000431837.1
ENST00000550616.1
ENST00000448290.2
ENST00000551736.1
IRAK4




interleukin-1 receptor-associated kinase 4




chr1_-_20126365 0.247 ENST00000294543.6
ENST00000375122.2
TMCO4

transmembrane and coiled-coil domains 4

chr11_+_45825616 0.247 ENST00000442528.2
ENST00000456334.1
ENST00000526817.1
SLC35C1


solute carrier family 35 (GDP-fucose transporter), member C1


chr11_-_62389577 0.246 ENST00000534715.1
B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr1_+_169337412 0.244 ENST00000426663.1
BLZF1
basic leucine zipper nuclear factor 1
chr12_-_53343602 0.242 ENST00000546897.1
ENST00000552551.1
KRT8

keratin 8

chr17_-_43568062 0.238 ENST00000421073.2
ENST00000584420.1
ENST00000589780.1
ENST00000430334.3
PLEKHM1



pleckstrin homology domain containing, family M (with RUN domain) member 1



chr11_-_119993734 0.236 ENST00000533302.1
TRIM29
tripartite motif containing 29
chr16_+_78133293 0.235 ENST00000566780.1
WWOX
WW domain containing oxidoreductase
chr17_+_38376042 0.234 ENST00000583130.1
ENST00000584296.1
WIPF2

WAS/WASL interacting protein family, member 2

chr11_+_94706973 0.233 ENST00000536741.1
KDM4D
lysine (K)-specific demethylase 4D
chr2_+_163200598 0.233 ENST00000437150.2
ENST00000453113.2
GCA

grancalcin, EF-hand calcium binding protein

chr5_-_138862326 0.232 ENST00000330794.4
TMEM173
transmembrane protein 173
chr7_+_100770328 0.232 ENST00000223095.4
ENST00000445463.2
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr11_+_123396528 0.232 ENST00000322282.7
ENST00000529750.1
GRAMD1B

GRAM domain containing 1B

chr11_+_82904746 0.231 ENST00000393389.3
ENST00000528722.1
ANKRD42

ankyrin repeat domain 42

chr17_-_80408569 0.229 ENST00000577696.1
ENST00000577471.1
ENST00000582545.2
ENST00000437807.2
ENST00000583617.1
ENST00000578913.1
ENST00000336995.7
ENST00000577834.1
ENST00000342572.8
ENST00000585064.1
ENST00000585080.1
ENST00000578919.1
ENST00000306645.5
ENST00000434650.2
C17orf62













chromosome 17 open reading frame 62













chr2_+_71295717 0.229 ENST00000418807.3
ENST00000443872.2
NAGK

N-acetylglucosamine kinase

chr1_-_184723701 0.229 ENST00000367512.3
EDEM3
ER degradation enhancer, mannosidase alpha-like 3
chr18_-_47813940 0.228 ENST00000586837.1
ENST00000412036.2
ENST00000589940.1
CXXC1


CXXC finger protein 1


chr2_+_71295416 0.228 ENST00000455662.2
ENST00000531934.1
NAGK

N-acetylglucosamine kinase

chr3_+_159481464 0.227 ENST00000467377.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr2_+_163200848 0.227 ENST00000233612.4
GCA
grancalcin, EF-hand calcium binding protein
chr2_-_96931679 0.226 ENST00000258439.3
ENST00000432959.1
TMEM127

transmembrane protein 127

chr6_+_83073952 0.226 ENST00000543496.1
TPBG
trophoblast glycoprotein
chr6_-_44233361 0.224 ENST00000275015.5
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr20_+_43104508 0.223 ENST00000262605.4
ENST00000372904.3
TTPAL

tocopherol (alpha) transfer protein-like

chr19_+_57791419 0.222 ENST00000537645.1
ZNF460
zinc finger protein 460
chrX_-_54069253 0.222 ENST00000425862.1
ENST00000433120.1
PHF8

PHD finger protein 8

chr16_+_88636875 0.222 ENST00000569435.1
ZC3H18
zinc finger CCCH-type containing 18
chr22_+_22020273 0.220 ENST00000412327.1
ENST00000335025.8
ENST00000398831.3
ENST00000492445.2
ENST00000458567.1
ENST00000406385.1
PPIL2





peptidylprolyl isomerase (cyclophilin)-like 2





chr11_-_9336117 0.220 ENST00000527813.1
ENST00000533723.1
TMEM41B

transmembrane protein 41B

chr21_-_46221684 0.219 ENST00000330942.5
UBE2G2
ubiquitin-conjugating enzyme E2G 2
chrX_-_153718988 0.218 ENST00000263512.4
ENST00000393587.4
ENST00000453912.1
SLC10A3


solute carrier family 10, member 3


chr19_+_35739897 0.218 ENST00000605618.1
ENST00000427250.1
ENST00000601623.1
LSR


lipolysis stimulated lipoprotein receptor


chr19_+_45681997 0.218 ENST00000433642.2
BLOC1S3
biogenesis of lysosomal organelles complex-1, subunit 3
chr5_-_176037105 0.217 ENST00000303991.4
GPRIN1
G protein regulated inducer of neurite outgrowth 1
chr12_+_27396901 0.217 ENST00000541191.1
ENST00000389032.3
STK38L

serine/threonine kinase 38 like

chr11_+_35222629 0.216 ENST00000526553.1
CD44
CD44 molecule (Indian blood group)
chr12_-_53343633 0.215 ENST00000546826.1
KRT8
keratin 8
chr15_-_74284558 0.214 ENST00000359750.4
ENST00000541638.1
ENST00000562453.1
STOML1


stomatin (EPB72)-like 1


chr11_+_35211511 0.214 ENST00000524922.1
CD44
CD44 molecule (Indian blood group)
chr14_+_35761580 0.212 ENST00000553809.1
ENST00000555764.1
ENST00000556506.1
PSMA6


proteasome (prosome, macropain) subunit, alpha type, 6


chr16_+_31044812 0.211 ENST00000313843.3
STX4
syntaxin 4
chr11_+_61891445 0.210 ENST00000394818.3
ENST00000533896.1
ENST00000278849.4
INCENP


inner centromere protein antigens 135/155kDa


chr11_+_94706804 0.210 ENST00000335080.5
KDM4D
lysine (K)-specific demethylase 4D
chr1_-_6659876 0.210 ENST00000496707.1
KLHL21
kelch-like family member 21
chr12_+_53645870 0.208 ENST00000329548.4
MFSD5
major facilitator superfamily domain containing 5
chr16_+_19729586 0.206 ENST00000564186.1
ENST00000541926.1
ENST00000433597.2
IQCK


IQ motif containing K


chr5_+_157158205 0.205 ENST00000231198.7
THG1L
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr5_+_96079240 0.205 ENST00000515663.1
CAST
calpastatin
chr16_+_77224732 0.203 ENST00000569610.1
ENST00000248248.3
ENST00000567291.1
ENST00000320859.6
ENST00000563612.1
ENST00000563279.1
MON1B





MON1 secretory trafficking family member B





chr3_-_130745403 0.203 ENST00000504725.1
ENST00000509060.1
ASTE1

asteroid homolog 1 (Drosophila)

chr3_+_50388126 0.202 ENST00000425346.1
ENST00000424512.1
ENST00000232508.5
ENST00000418577.1
ENST00000606589.1
CYB561D2



XXcos-LUCA11.5
cytochrome b561 family, member D2



Uncharacterized protein
chr7_+_138915102 0.202 ENST00000486663.1
UBN2
ubinuclein 2
chr17_+_78193443 0.201 ENST00000577155.1
SLC26A11
solute carrier family 26 (anion exchanger), member 11
chr9_-_140095186 0.201 ENST00000409012.4
TPRN
taperin
chr11_-_9482010 0.200 ENST00000596206.1
AC132192.1
LOC644656 protein; Uncharacterized protein
chr11_-_60674000 0.199 ENST00000546152.1
PRPF19
pre-mRNA processing factor 19
chr2_+_113342163 0.198 ENST00000409719.1
CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr19_-_55791540 0.197 ENST00000433386.2
HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr18_-_47814032 0.197 ENST00000589548.1
ENST00000591474.1
CXXC1

CXXC finger protein 1

chr19_-_1479532 0.196 ENST00000436106.2
C19orf25
chromosome 19 open reading frame 25
chr16_+_70557685 0.196 ENST00000302516.5
ENST00000566095.2
ENST00000577085.1
ENST00000567654.1
SF3B3



splicing factor 3b, subunit 3, 130kDa



chr9_-_115095851 0.196 ENST00000343327.2
PTBP3
polypyrimidine tract binding protein 3
chr18_+_56806701 0.196 ENST00000587834.1
SEC11C
SEC11 homolog C (S. cerevisiae)
chr11_+_66610883 0.195 ENST00000309657.3
ENST00000524506.1
RCE1

Ras converting CAAX endopeptidase 1

chr2_+_198318217 0.194 ENST00000409398.1
COQ10B
coenzyme Q10 homolog B (S. cerevisiae)
chr11_-_68039364 0.194 ENST00000533310.1
ENST00000304271.6
ENST00000527280.1
C11orf24


chromosome 11 open reading frame 24


chr1_-_52499443 0.193 ENST00000371614.1
KTI12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr6_+_47666275 0.192 ENST00000327753.3
ENST00000283303.2
GPR115

G protein-coupled receptor 115

chr3_-_42003479 0.192 ENST00000420927.1
ULK4
unc-51 like kinase 4
chr11_+_17281900 0.192 ENST00000530527.1
NUCB2
nucleobindin 2
chr5_-_43397184 0.191 ENST00000513525.1
CCL28
chemokine (C-C motif) ligand 28
chr11_-_45939565 0.191 ENST00000525192.1
ENST00000378750.5
PEX16

peroxisomal biogenesis factor 16

chr12_+_108908962 0.190 ENST00000552695.1
ENST00000552758.1
ENST00000361549.2
FICD


FIC domain containing


chrX_+_55744166 0.190 ENST00000374941.4
ENST00000414239.1
RRAGB

Ras-related GTP binding B

chr11_-_62389621 0.189 ENST00000531383.1
ENST00000265471.5
B3GAT3

beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)

chr17_+_38375574 0.189 ENST00000323571.4
ENST00000585043.1
ENST00000394103.3
ENST00000536600.1
WIPF2



WAS/WASL interacting protein family, member 2



chr12_-_133405409 0.189 ENST00000545875.1
ENST00000456883.2
GOLGA3

golgin A3

chr9_-_35619539 0.188 ENST00000396757.1
CD72
CD72 molecule
chr17_+_4843654 0.188 ENST00000575111.1
RNF167
ring finger protein 167
chr8_+_56792355 0.187 ENST00000519728.1
LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr15_+_75074410 0.186 ENST00000439220.2
CSK
c-src tyrosine kinase
chr2_-_219537134 0.186 ENST00000295704.2
RNF25
ring finger protein 25
chr17_-_73844722 0.185 ENST00000586257.1
WBP2
WW domain binding protein 2
chr12_-_6740802 0.184 ENST00000431922.1
LPAR5
lysophosphatidic acid receptor 5
chr16_-_31085033 0.183 ENST00000414399.1
ZNF668
zinc finger protein 668
chr2_-_75788428 0.180 ENST00000432649.1
EVA1A
eva-1 homolog A (C. elegans)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.4 2.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.2 0.6 GO:0072683 T cell extravasation(GO:0072683)
0.2 0.8 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.2 0.8 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.2 0.5 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.4 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.1 0.4 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 0.7 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.1 0.5 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.4 GO:0019085 early viral transcription(GO:0019085)
0.1 0.5 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 0.7 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.3 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.1 0.3 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.1 0.3 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.1 0.3 GO:0070666 regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 0.4 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.1 0.9 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.4 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.1 0.2 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 0.2 GO:0001300 chronological cell aging(GO:0001300)
0.1 0.3 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 0.2 GO:0001743 optic placode formation(GO:0001743)
0.1 0.5 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.4 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.6 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 0.2 GO:0043311 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.2 GO:0035811 negative regulation of urine volume(GO:0035811)
0.1 0.5 GO:0036343 psychomotor behavior(GO:0036343)
0.1 0.4 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 0.4 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 0.3 GO:0036369 transcription factor catabolic process(GO:0036369)
0.1 0.2 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 0.3 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.2 GO:0070781 response to biotin(GO:0070781)
0.1 0.9 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.1 0.9 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.1 0.7 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.2 GO:0003162 atrioventricular node development(GO:0003162)
0.0 0.2 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.1 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.0 0.1 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.0 0.2 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.0 1.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.4 GO:0097466 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0 0.4 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.3 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.0 0.1 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.5 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.0 0.2 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.1 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.0 0.2 GO:0036071 N-glycan fucosylation(GO:0036071)
0.0 0.2 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0 0.2 GO:0035936 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.0 0.0 GO:0006408 snRNA export from nucleus(GO:0006408)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.2 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.1 GO:0061349 cardiac right atrium morphogenesis(GO:0003213) chemoattraction of serotonergic neuron axon(GO:0036517) positive regulation of anagen(GO:0051885) mesodermal to mesenchymal transition involved in gastrulation(GO:0060809) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) regulation of cell proliferation in midbrain(GO:1904933) negative regulation of cell proliferation in midbrain(GO:1904934) planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation(GO:1904955)
0.0 0.2 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.0 0.1 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.0 0.4 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.0 0.2 GO:2000538 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.5 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0070859 lipid transport involved in lipid storage(GO:0010877) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0 0.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.0 0.1 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.5 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0 0.1 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.4 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.1 GO:0072720 response to dithiothreitol(GO:0072720)
0.0 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.0 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.0 1.0 GO:0045730 respiratory burst(GO:0045730)
0.0 0.2 GO:0072719 cellular response to cisplatin(GO:0072719)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.1 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.2 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0 0.1 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.1 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.0 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.1 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.3 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.3 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.1 GO:0019086 late viral transcription(GO:0019086)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.8 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.5 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.3 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.4 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0 0.2 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.1 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.1 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.0 0.2 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 1.9 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.4 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.4 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.1 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.0 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.0 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.5 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.3 GO:0035456 response to interferon-beta(GO:0035456)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:2000782 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.7 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.2 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.1 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.0 0.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.1 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.0 0.1 GO:0032962 regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.0 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.1 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.0 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.2 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.0 GO:0060011 penile erection(GO:0043084) Sertoli cell proliferation(GO:0060011)
0.0 0.3 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.1 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.2 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.2 GO:0033151 V(D)J recombination(GO:0033151)
0.0 0.3 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.0 0.0 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.0 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.4 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:0006266 DNA ligation(GO:0006266)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.5 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.1 1.1 GO:0032010 phagolysosome(GO:0032010)
0.1 0.9 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 1.7 GO:0033391 chromatoid body(GO:0033391)
0.1 0.4 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.1 0.2 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 0.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.5 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 0.2 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.1 0.2 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.3 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.3 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.1 GO:0032302 MutSbeta complex(GO:0032302)
0.0 0.4 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 1.1 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.4 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.5 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.2 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 0.9 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.9 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.6 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.0 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.2 GO:0010369 chromocenter(GO:0010369)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 2.9 GO:0001650 fibrillar center(GO:0001650)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.0 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.2 2.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 0.7 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.1 0.4 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 1.4 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.4 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.4 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.3 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.1 0.4 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.1 0.4 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.2 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.1 0.3 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 1.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.2 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.1 0.3 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.3 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.5 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.3 GO:0051373 FATZ binding(GO:0051373)
0.0 0.2 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.2 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.5 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.4 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.1 GO:0032181 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.0 0.3 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.0 0.4 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0004423 iduronate-2-sulfatase activity(GO:0004423)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.2 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.0 0.9 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.1 GO:0005115 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.0 0.3 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0008841 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.0 0.2 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.1 GO:0045142 triplex DNA binding(GO:0045142)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.1 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.8 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.1 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.0 0.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 0.2 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.0 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 0.1 GO:0004827 proline-tRNA ligase activity(GO:0004827)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.1 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.5 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.8 GO:0008009 chemokine activity(GO:0008009)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.3 GO:0004576 oligosaccharyl transferase activity(GO:0004576)
0.0 0.2 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.5 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.2 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.0 GO:0001083 transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083)
0.0 0.0 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.0 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.0 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.8 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.0 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.0 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.9 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.7 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 1.7 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor
0.0 1.3 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.5 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 0.2 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 1.1 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.3 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.5 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 4.3 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.0 0.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.5 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.5 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.5 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.6 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.3 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.6 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.2 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.9 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.6 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.2 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.2 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10