Motif ID: EGR3_EGR2

Z-value: 0.937

Transcription factors associated with EGR3_EGR2:

Gene SymbolEntrez IDGene Name
EGR2 ENSG00000122877.9 EGR2
EGR3 ENSG00000179388.8 EGR3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
EGR3hg19_v2_chr8_-_22550815_22550844-0.353.5e-01Click!
EGR2hg19_v2_chr10_-_64576105_645761330.107.9e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of EGR3_EGR2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_176924562 3.809 ENST00000359895.2
ENST00000355572.2
ENST00000355841.2
ENST00000393551.1
ENST00000505074.1
ENST00000356618.4
ENST00000393546.4
PDLIM7






PDZ and LIM domain 7 (enigma)






chr16_+_3070356 1.809 ENST00000341627.5
ENST00000575124.1
ENST00000575836.1
TNFRSF12A


tumor necrosis factor receptor superfamily, member 12A


chr16_+_3070313 1.785 ENST00000326577.4
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr19_-_49371711 1.768 ENST00000355496.5
ENST00000263265.6
PLEKHA4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr15_+_39873268 1.627 ENST00000397591.2
ENST00000260356.5
THBS1

thrombospondin 1

chr14_-_100842588 1.332 ENST00000556645.1
ENST00000556209.1
ENST00000556504.1
ENST00000556435.1
ENST00000554772.1
ENST00000553581.1
ENST00000553769.2
ENST00000554605.1
ENST00000557722.1
ENST00000553413.1
ENST00000553524.1
ENST00000358655.4
WARS











tryptophanyl-tRNA synthetase











chr3_+_101546827 1.219 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ


nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta


chr10_+_23728198 1.115 ENST00000376495.3
OTUD1
OTU domain containing 1
chr1_+_68150744 1.017 ENST00000370986.4
ENST00000370985.3
GADD45A

growth arrest and DNA-damage-inducible, alpha

chr11_+_66624527 1.016 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr1_-_94312706 0.981 ENST00000370244.1
BCAR3
breast cancer anti-estrogen resistance 3
chr6_+_86159821 0.941 ENST00000369651.3
NT5E
5'-nucleotidase, ecto (CD73)
chr5_-_176923846 0.919 ENST00000506537.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr6_+_86159765 0.887 ENST00000369646.3
ENST00000257770.3
NT5E

5'-nucleotidase, ecto (CD73)

chr7_+_100770328 0.880 ENST00000223095.4
ENST00000445463.2
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr6_+_30689350 0.875 ENST00000330914.3
TUBB
tubulin, beta class I
chr5_+_40679584 0.851 ENST00000302472.3
PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr6_+_30689401 0.840 ENST00000396389.1
ENST00000396384.1
TUBB

tubulin, beta class I

chr5_-_176923803 0.829 ENST00000506161.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr8_+_94929077 0.812 ENST00000297598.4
ENST00000520614.1
PDP1

pyruvate dehyrogenase phosphatase catalytic subunit 1

chr8_+_94929168 0.792 ENST00000518107.1
ENST00000396200.3
PDP1

pyruvate dehyrogenase phosphatase catalytic subunit 1

chr8_+_94929110 0.787 ENST00000520728.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr9_-_130742792 0.784 ENST00000373095.1
FAM102A
family with sequence similarity 102, member A
chr22_+_29138013 0.780 ENST00000216027.3
ENST00000398941.2
HSCB

HscB mitochondrial iron-sulfur cluster co-chaperone

chr3_+_50192833 0.775 ENST00000426511.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr19_+_45504688 0.768 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB


v-rel avian reticuloendotheliosis viral oncogene homolog B


chr9_+_34989638 0.765 ENST00000453597.3
ENST00000335998.3
ENST00000312316.5
DNAJB5


DnaJ (Hsp40) homolog, subfamily B, member 5


chr11_-_64546202 0.755 ENST00000377390.3
ENST00000227503.9
ENST00000377394.3
ENST00000422298.2
ENST00000334944.5
SF1




splicing factor 1




chr6_+_138188551 0.727 ENST00000237289.4
ENST00000433680.1
TNFAIP3

tumor necrosis factor, alpha-induced protein 3

chr2_-_98612350 0.721 ENST00000186436.5
TMEM131
transmembrane protein 131
chr14_-_69445793 0.721 ENST00000538545.2
ENST00000394419.4
ACTN1

actinin, alpha 1

chr5_+_52285144 0.720 ENST00000296585.5
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chrX_-_129402857 0.670 ENST00000447817.1
ENST00000370978.4
ZNF280C

zinc finger protein 280C

chr1_+_26606608 0.660 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr1_+_9648921 0.659 ENST00000377376.4
ENST00000340305.5
ENST00000340381.6
TMEM201


transmembrane protein 201


chr11_-_64545941 0.651 ENST00000377387.1
SF1
splicing factor 1
chr17_+_79008940 0.649 ENST00000392411.3
ENST00000575989.1
ENST00000321280.7
ENST00000428708.2
ENST00000575712.1
ENST00000575245.1
ENST00000435091.3
ENST00000321300.6
BAIAP2







BAI1-associated protein 2







chr4_-_25864581 0.648 ENST00000399878.3
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr2_-_98612379 0.648 ENST00000425805.2
TMEM131
transmembrane protein 131
chr8_+_94929273 0.641 ENST00000518573.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr9_-_101017900 0.640 ENST00000375066.5
TBC1D2
TBC1 domain family, member 2
chr16_+_1203194 0.634 ENST00000348261.5
ENST00000358590.4
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr20_+_34894247 0.632 ENST00000373913.3
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr20_+_44035200 0.614 ENST00000372717.1
ENST00000360981.4
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr22_-_29137771 0.610 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
CHEK2









checkpoint kinase 2









chr1_-_85156417 0.599 ENST00000422026.1
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chrX_-_19905577 0.596 ENST00000379697.3
SH3KBP1
SH3-domain kinase binding protein 1
chr6_+_116832789 0.591 ENST00000368599.3
FAM26E
family with sequence similarity 26, member E
chr19_-_54693521 0.585 ENST00000391754.1
ENST00000245615.1
ENST00000431666.2
MBOAT7


membrane bound O-acyltransferase domain containing 7


chr6_+_138188378 0.582 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr14_-_69445968 0.572 ENST00000438964.2
ACTN1
actinin, alpha 1
chr1_+_161494036 0.567 ENST00000309758.4
HSPA6
heat shock 70kDa protein 6 (HSP70B')
chr12_-_109125285 0.558 ENST00000552871.1
ENST00000261401.3
CORO1C

coronin, actin binding protein, 1C

chr2_-_219433014 0.551 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
USP37




ubiquitin specific peptidase 37




chr10_-_108924284 0.547 ENST00000344440.6
ENST00000263054.6
SORCS1

sortilin-related VPS10 domain containing receptor 1

chr5_+_145583107 0.546 ENST00000506502.1
RBM27
RNA binding motif protein 27
chr5_-_142784101 0.536 ENST00000503201.1
ENST00000502892.1
NR3C1

nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

chr3_-_126194707 0.534 ENST00000336332.5
ENST00000389709.3
ZXDC

ZXD family zinc finger C

chr19_-_40931891 0.531 ENST00000357949.4
SERTAD1
SERTA domain containing 1
chr16_+_50776021 0.525 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD


cylindromatosis (turban tumor syndrome)


chr15_+_74833518 0.521 ENST00000346246.5
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr18_+_3449695 0.517 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chr19_-_41859814 0.515 ENST00000221930.5
TGFB1
transforming growth factor, beta 1
chr15_+_73976545 0.511 ENST00000318443.5
ENST00000537340.2
ENST00000318424.5
CD276


CD276 molecule


chr18_+_3449821 0.509 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1


TGFB-induced factor homeobox 1


chr6_+_43140095 0.502 ENST00000457278.2
SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr7_-_100026280 0.500 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
ZCWPW1



zinc finger, CW type with PWWP domain 1



chr20_+_49348109 0.493 ENST00000396039.1
PARD6B
par-6 family cell polarity regulator beta
chr19_-_54693401 0.486 ENST00000338624.6
MBOAT7
membrane bound O-acyltransferase domain containing 7
chr3_-_32612263 0.482 ENST00000432458.2
ENST00000424991.1
ENST00000273130.4
DYNC1LI1


dynein, cytoplasmic 1, light intermediate chain 1


chr20_+_44034676 0.479 ENST00000372723.3
ENST00000372722.3
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr4_+_150999418 0.473 ENST00000296550.7
DCLK2
doublecortin-like kinase 2
chrX_-_154033686 0.471 ENST00000453245.1
ENST00000428488.1
ENST00000369531.1
MPP1


membrane protein, palmitoylated 1, 55kDa


chr1_+_237205476 0.470 ENST00000366574.2
RYR2
ryanodine receptor 2 (cardiac)
chr2_+_191745535 0.469 ENST00000320717.3
GLS
glutaminase
chr6_+_12012170 0.466 ENST00000487103.1
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr1_-_33647267 0.460 ENST00000291416.5
TRIM62
tripartite motif containing 62
chr9_-_103115135 0.448 ENST00000537512.1
TEX10
testis expressed 10
chr9_-_103115185 0.445 ENST00000374902.4
TEX10
testis expressed 10
chr17_+_72428218 0.443 ENST00000392628.2
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr17_+_72428266 0.440 ENST00000582473.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr14_+_100842735 0.427 ENST00000554998.1
ENST00000402312.3
ENST00000335290.6
ENST00000554175.1
WDR25



WD repeat domain 25



chr20_-_17662878 0.425 ENST00000377813.1
ENST00000377807.2
ENST00000360807.4
ENST00000398782.2
RRBP1



ribosome binding protein 1



chr2_+_233562015 0.424 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
GIGYF2














GRB10 interacting GYF protein 2














chr20_-_17662705 0.421 ENST00000455029.2
RRBP1
ribosome binding protein 1
chr17_-_41623691 0.420 ENST00000545954.1
ETV4
ets variant 4
chr1_-_38471156 0.419 ENST00000373016.3
FHL3
four and a half LIM domains 3
chrX_-_19905703 0.407 ENST00000397821.3
SH3KBP1
SH3-domain kinase binding protein 1
chr22_-_24181174 0.407 ENST00000318109.7
ENST00000406855.3
ENST00000404056.1
ENST00000476077.1
DERL3



derlin 3



chr11_-_62313090 0.406 ENST00000528508.1
ENST00000533365.1
AHNAK

AHNAK nucleoprotein

chrX_+_107068959 0.405 ENST00000451923.1
MID2
midline 2
chr17_-_41623716 0.405 ENST00000319349.5
ETV4
ets variant 4
chr19_-_38714847 0.403 ENST00000420980.2
ENST00000355526.4
DPF1

D4, zinc and double PHD fingers family 1

chr15_+_72410660 0.399 ENST00000564082.1
SENP8
SUMO/sentrin specific peptidase family member 8
chr2_+_149402553 0.393 ENST00000258484.6
ENST00000409654.1
EPC2

enhancer of polycomb homolog 2 (Drosophila)

chr15_+_72410629 0.388 ENST00000340912.4
ENST00000544171.1
SENP8

SUMO/sentrin specific peptidase family member 8

chr6_-_112575912 0.388 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4


laminin, alpha 4


chr1_-_85742773 0.386 ENST00000370580.1
BCL10
B-cell CLL/lymphoma 10
chr2_-_158732340 0.383 ENST00000539637.1
ENST00000413751.1
ENST00000434821.1
ENST00000424669.1
ACVR1



activin A receptor, type I



chr15_-_73925575 0.383 ENST00000562924.1
ENST00000563691.1
ENST00000565325.1
ENST00000542234.1
NPTN



neuroplastin



chrX_-_48814278 0.382 ENST00000455452.1
OTUD5
OTU domain containing 5
chrX_-_154033793 0.380 ENST00000369534.3
ENST00000413259.3
MPP1

membrane protein, palmitoylated 1, 55kDa

chr12_+_79258444 0.378 ENST00000261205.4
SYT1
synaptotagmin I
chr3_+_159481464 0.375 ENST00000467377.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr6_-_112575687 0.374 ENST00000521398.1
ENST00000424408.2
ENST00000243219.3
LAMA4


laminin, alpha 4


chr17_+_37026284 0.374 ENST00000433206.2
ENST00000435347.3
LASP1

LIM and SH3 protein 1

chr22_-_29138386 0.373 ENST00000544772.1
CHEK2
checkpoint kinase 2
chr17_+_46985823 0.371 ENST00000508468.2
UBE2Z
ubiquitin-conjugating enzyme E2Z
chr15_+_75494214 0.371 ENST00000394987.4
C15orf39
chromosome 15 open reading frame 39
chr5_-_176037105 0.368 ENST00000303991.4
GPRIN1
G protein regulated inducer of neurite outgrowth 1
chr19_-_42758040 0.365 ENST00000593944.1
ERF
Ets2 repressor factor
chrX_-_48814810 0.364 ENST00000376488.3
ENST00000396743.3
ENST00000156084.4
OTUD5


OTU domain containing 5


chr16_+_28834303 0.364 ENST00000340394.8
ENST00000325215.6
ENST00000395547.2
ENST00000336783.4
ENST00000382686.4
ENST00000564304.1
ATXN2L





ataxin 2-like





chr16_+_31044413 0.361 ENST00000394998.1
STX4
syntaxin 4
chr12_-_1703331 0.360 ENST00000339235.3
FBXL14
F-box and leucine-rich repeat protein 14
chr17_+_37026106 0.360 ENST00000318008.6
LASP1
LIM and SH3 protein 1
chr1_-_85156216 0.360 ENST00000342203.3
ENST00000370612.4
SSX2IP

synovial sarcoma, X breakpoint 2 interacting protein

chr11_+_66886717 0.360 ENST00000398645.2
KDM2A
lysine (K)-specific demethylase 2A
chr17_+_46985731 0.359 ENST00000360943.5
UBE2Z
ubiquitin-conjugating enzyme E2Z
chr12_+_79258547 0.358 ENST00000457153.2
SYT1
synaptotagmin I
chr6_-_112575758 0.357 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
LAMA4



laminin, alpha 4



chr19_-_344786 0.354 ENST00000264819.4
MIER2
mesoderm induction early response 1, family member 2
chr1_-_9189229 0.352 ENST00000377411.4
GPR157
G protein-coupled receptor 157
chr20_+_48429356 0.352 ENST00000361573.2
ENST00000541138.1
ENST00000539601.1
SLC9A8


solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8


chr7_+_143078652 0.346 ENST00000354434.4
ENST00000449423.2
ZYX

zyxin

chr1_-_43833628 0.343 ENST00000413844.2
ENST00000372458.3
ELOVL1

ELOVL fatty acid elongase 1

chr4_+_103422499 0.343 ENST00000511926.1
ENST00000507079.1
NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

chr3_-_192635943 0.343 ENST00000392452.2
MB21D2
Mab-21 domain containing 2
chr9_+_131709966 0.339 ENST00000372577.2
NUP188
nucleoporin 188kDa
chr20_+_60878005 0.338 ENST00000253003.2
ADRM1
adhesion regulating molecule 1
chr17_-_1619491 0.338 ENST00000570416.1
ENST00000575626.1
ENST00000610106.1
ENST00000608198.1
ENST00000609442.1
ENST00000334146.3
ENST00000576489.1
ENST00000608245.1
ENST00000609398.1
ENST00000608913.1
ENST00000574016.1
ENST00000571091.1
ENST00000573127.1
ENST00000609990.1
ENST00000576749.1
MIR22HG














MIR22 host gene (non-protein coding)














chr16_+_31044812 0.337 ENST00000313843.3
STX4
syntaxin 4
chr1_-_160068465 0.337 ENST00000314485.7
ENST00000368086.1
IGSF8

immunoglobulin superfamily, member 8

chrX_+_107069063 0.337 ENST00000262843.6
MID2
midline 2
chr3_+_50192457 0.337 ENST00000414301.1
ENST00000450338.1
SEMA3F

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F

chr17_+_72772621 0.334 ENST00000335464.5
ENST00000417024.2
ENST00000578764.1
ENST00000582773.1
ENST00000582330.1
TMEM104




transmembrane protein 104




chr3_+_50192537 0.334 ENST00000002829.3
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr22_+_31090793 0.332 ENST00000332585.6
ENST00000382310.3
ENST00000446658.2
OSBP2


oxysterol binding protein 2


chr7_+_142985467 0.332 ENST00000392925.2
CASP2
caspase 2, apoptosis-related cysteine peptidase
chr2_+_133174147 0.331 ENST00000329321.3
GPR39
G protein-coupled receptor 39
chr16_+_50775971 0.331 ENST00000311559.9
ENST00000564326.1
ENST00000566206.1
CYLD


cylindromatosis (turban tumor syndrome)


chr6_+_12012536 0.331 ENST00000379388.2
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr15_+_52311398 0.330 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr13_+_110959598 0.330 ENST00000360467.5
COL4A2
collagen, type IV, alpha 2
chr20_+_35202909 0.330 ENST00000558028.1
ENST00000560025.1
ENST00000558530.1
TGIF2

TGIF2-C20orf24
TGFB-induced factor homeobox 2

TGIF2-C20orf24 readthrough
chr19_+_1249869 0.330 ENST00000591446.2
MIDN
midnolin
chr1_-_85156090 0.326 ENST00000605755.1
ENST00000437941.2
SSX2IP

synovial sarcoma, X breakpoint 2 interacting protein

chr12_+_49658855 0.324 ENST00000549183.1
TUBA1C
tubulin, alpha 1c
chr3_+_50192499 0.321 ENST00000413852.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chrX_-_154033661 0.319 ENST00000393531.1
MPP1
membrane protein, palmitoylated 1, 55kDa
chr16_-_402639 0.318 ENST00000262320.3
AXIN1
axin 1
chr16_-_838329 0.316 ENST00000563560.1
ENST00000569601.1
ENST00000565809.1
ENST00000565377.1
ENST00000007264.2
ENST00000567114.1
RPUSD1





RNA pseudouridylate synthase domain containing 1





chr17_-_1619535 0.315 ENST00000573075.1
ENST00000574306.1
MIR22HG

MIR22 host gene (non-protein coding)

chr2_+_110371905 0.312 ENST00000356454.3
SOWAHC
sosondowah ankyrin repeat domain family member C
chrX_+_21959108 0.312 ENST00000457085.1
SMS
spermine synthase
chr11_+_86511549 0.310 ENST00000533902.2
PRSS23
protease, serine, 23
chr19_-_56110859 0.310 ENST00000221665.3
ENST00000592585.1
FIZ1

FLT3-interacting zinc finger 1

chr9_-_132515302 0.306 ENST00000340607.4
PTGES
prostaglandin E synthase
chr21_-_33104367 0.303 ENST00000286835.7
ENST00000399804.1
SCAF4

SR-related CTD-associated factor 4

chr11_+_560956 0.303 ENST00000397582.3
ENST00000344375.4
ENST00000397583.3
RASSF7


Ras association (RalGDS/AF-6) domain family (N-terminal) member 7


chr4_-_153274078 0.302 ENST00000263981.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr12_-_53297432 0.302 ENST00000546900.1
KRT8
keratin 8
chr6_+_134274322 0.301 ENST00000367871.1
ENST00000237264.4
TBPL1

TBP-like 1

chr6_+_134274354 0.300 ENST00000367869.1
TBPL1
TBP-like 1
chr7_+_20370300 0.300 ENST00000537992.1
ITGB8
integrin, beta 8
chr2_+_149402009 0.298 ENST00000457184.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr16_-_2185899 0.297 ENST00000262304.4
ENST00000423118.1
PKD1

polycystic kidney disease 1 (autosomal dominant)

chr1_+_109289279 0.297 ENST00000370008.3
STXBP3
syntaxin binding protein 3
chr1_-_160068645 0.295 ENST00000448417.1
IGSF8
immunoglobulin superfamily, member 8
chr6_+_35310312 0.295 ENST00000448077.2
ENST00000360694.3
ENST00000418635.2
ENST00000444397.1
PPARD



peroxisome proliferator-activated receptor delta



chr21_-_33104260 0.294 ENST00000434667.3
SCAF4
SR-related CTD-associated factor 4
chr20_+_48429233 0.292 ENST00000417961.1
SLC9A8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr6_-_31088214 0.292 ENST00000376288.2
CDSN
corneodesmosin
chr4_+_38665810 0.290 ENST00000261438.5
ENST00000514033.1
KLF3

Kruppel-like factor 3 (basic)

chr11_+_35639735 0.290 ENST00000317811.4
FJX1
four jointed box 1 (Drosophila)
chr13_-_110959478 0.289 ENST00000543140.1
ENST00000375820.4
COL4A1

collagen, type IV, alpha 1

chr3_+_159481988 0.289 ENST00000472451.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr1_-_155948218 0.289 ENST00000313667.4
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr19_-_55770311 0.288 ENST00000412770.2
PPP6R1
protein phosphatase 6, regulatory subunit 1
chr1_+_38259459 0.287 ENST00000373045.6
MANEAL
mannosidase, endo-alpha-like
chr12_+_69864129 0.281 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
FRS2









fibroblast growth factor receptor substrate 2









chr3_-_49851313 0.281 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr1_+_38259540 0.280 ENST00000397631.3
MANEAL
mannosidase, endo-alpha-like
chr11_-_122932730 0.280 ENST00000532182.1
ENST00000524590.1
ENST00000528292.1
ENST00000533540.1
ENST00000525463.1
HSPA8




heat shock 70kDa protein 8




chr19_-_42759300 0.279 ENST00000222329.4
ERF
Ets2 repressor factor
chr7_+_142985308 0.278 ENST00000310447.5
CASP2
caspase 2, apoptosis-related cysteine peptidase
chr6_-_32157947 0.278 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr1_-_29508321 0.275 ENST00000546138.1
SRSF4
serine/arginine-rich splicing factor 4
chrX_-_53350522 0.275 ENST00000396435.3
ENST00000375368.5
IQSEC2

IQ motif and Sec7 domain 2

chr19_-_54693146 0.273 ENST00000414665.1
ENST00000453320.1
MBOAT7

membrane bound O-acyltransferase domain containing 7

chr3_+_10206545 0.272 ENST00000256458.4
IRAK2
interleukin-1 receptor-associated kinase 2
chrX_+_21958814 0.272 ENST00000379404.1
ENST00000415881.2
SMS

spermine synthase

chr14_-_51027838 0.271 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr2_+_74056066 0.270 ENST00000339566.3
ENST00000409707.1
ENST00000452725.1
ENST00000432295.2
ENST00000424659.1
ENST00000394073.1
STAMBP





STAM binding protein





chr15_-_73925651 0.270 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
NPTN


neuroplastin


chr4_+_103422471 0.268 ENST00000226574.4
ENST00000394820.4
NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

chr6_+_37787704 0.267 ENST00000474522.1
ZFAND3
zinc finger, AN1-type domain 3
chr2_+_73441350 0.266 ENST00000389501.4
SMYD5
SMYD family member 5
chr2_+_191745560 0.264 ENST00000338435.4
GLS
glutaminase
chr17_-_1619568 0.264 ENST00000571595.1
MIR22HG
MIR22 host gene (non-protein coding)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0002605 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
0.5 1.4 GO:0070429 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.4 1.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.4 1.8 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.4 3.6 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.3 1.0 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.3 0.9 GO:0001300 chronological cell aging(GO:0001300)
0.2 0.7 GO:0033341 regulation of collagen binding(GO:0033341)
0.2 0.7 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.2 1.3 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.2 0.8 GO:0006597 spermine biosynthetic process(GO:0006597)
0.2 0.6 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.2 0.6 GO:0001743 optic placode formation(GO:0001743)
0.2 0.7 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.2 0.5 GO:0071629 cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071629)
0.2 0.5 GO:0052553 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.2 0.5 GO:0060532 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.2 0.5 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.1 0.1 GO:0040031 snRNA modification(GO:0040031)
0.1 1.8 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.1 3.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.6 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.5 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1 0.4 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 1.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.7 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.9 GO:2000416 regulation of eosinophil migration(GO:2000416)
0.1 0.8 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.5 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1 0.7 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.8 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1 0.4 GO:0003274 endocardial cushion fusion(GO:0003274)
0.1 0.6 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.1 0.6 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.1 0.3 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.3 GO:0061349 chemoattraction of serotonergic neuron axon(GO:0036517) mesodermal to mesenchymal transition involved in gastrulation(GO:0060809) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) negative regulation of cell proliferation in midbrain(GO:1904934) planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation(GO:1904955)
0.1 0.3 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.1 1.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.2 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.1 0.6 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 0.2 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.1 0.3 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.1 0.2 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1 0.2 GO:0072720 response to dithiothreitol(GO:0072720)
0.1 0.2 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 0.3 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 0.2 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.6 GO:0035865 cellular response to potassium ion(GO:0035865)
0.1 1.6 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 0.2 GO:0060381 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.1 0.6 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.7 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.6 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.6 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 0.3 GO:0015862 uridine transport(GO:0015862)
0.1 0.3 GO:0019087 transformation of host cell by virus(GO:0019087) neuron projection maintenance(GO:1990535)
0.1 1.3 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.1 0.3 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 1.6 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.4 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.2 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.1 0.2 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 0.2 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 0.5 GO:0046836 glycolipid transport(GO:0046836)
0.1 0.2 GO:0090340 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of pancreatic juice secretion(GO:0090187) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.1 1.5 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 0.9 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.2 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.1 0.1 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.0 0.8 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0060025 regulation of synaptic activity(GO:0060025)
0.0 0.5 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.2 GO:0010157 response to chlorate(GO:0010157)
0.0 0.0 GO:0044026 DNA hypermethylation(GO:0044026) hypermethylation of CpG island(GO:0044027)
0.0 0.5 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.5 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.3 GO:2000782 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.6 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.3 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.5 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.3 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.3 GO:1990090 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.0 0.3 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.3 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
0.0 0.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.2 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0099541 retrograde trans-synaptic signaling(GO:0098917) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.0 4.2 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.5 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.3 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.1 GO:1904585 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.0 0.4 GO:0032264 IMP salvage(GO:0032264)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.3 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 1.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.4 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.1 GO:0061009 common bile duct development(GO:0061009)
0.0 0.2 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0 0.1 GO:0072141 renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.0 0.2 GO:0006311 meiotic gene conversion(GO:0006311)
0.0 0.5 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.8 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 1.2 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.2 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.2 GO:0043335 protein unfolding(GO:0043335)
0.0 0.3 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 1.2 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.1 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 0.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.1 GO:2000697 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:1902866 regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.0 0.2 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.2 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.3 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.8 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0009052 D-ribose metabolic process(GO:0006014) pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.5 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.3 GO:0046465 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0 0.1 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.0 0.4 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.1 GO:0036090 cleavage furrow ingression(GO:0036090) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.2 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.5 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 1.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.5 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.4 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.0 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.3 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.3 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.2 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.0 0.1 GO:0009996 negative regulation of cell fate specification(GO:0009996)
0.0 0.2 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.0 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.2 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.3 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.0 GO:1904674 regulation of somatic stem cell population maintenance(GO:1904672) positive regulation of somatic stem cell population maintenance(GO:1904674)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.2 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.1 GO:0043633 polyadenylation-dependent RNA catabolic process(GO:0043633) polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.0 0.3 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.2 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)
0.0 0.3 GO:0002544 chronic inflammatory response(GO:0002544)
0.0 0.5 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 1.4 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.2 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.1 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.3 GO:0007097 nuclear migration(GO:0007097)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.3 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.5 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.5 GO:0046596 regulation of viral entry into host cell(GO:0046596)
0.0 0.1 GO:2001016 positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0 0.2 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.1 GO:0032204 regulation of telomere maintenance(GO:0032204) regulation of telomere maintenance via telomerase(GO:0032210) regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.2 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.0 0.2 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.1 GO:0060042 retina morphogenesis in camera-type eye(GO:0060042)
0.0 0.1 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.0 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.3 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.0 GO:0090135 actin filament branching(GO:0090135)
0.0 0.1 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.1 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 1.3 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.5 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.1 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.1 GO:0043129 surfactant homeostasis(GO:0043129)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.3 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.3 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.9 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 0.0 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.3 GO:0014887 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.1 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.3 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.3 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0021586 pons maturation(GO:0021586)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:2000188 regulation of cholesterol homeostasis(GO:2000188)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 1.5 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.4 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.5 GO:0016600 flotillin complex(GO:0016600)
0.1 2.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.7 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.2 GO:0001740 X chromosome(GO:0000805) Barr body(GO:0001740)
0.1 0.5 GO:0032449 CBM complex(GO:0032449)
0.1 0.7 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.3 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.2 GO:0032302 MutSbeta complex(GO:0032302)
0.1 1.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.5 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 0.6 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.3 GO:0042643 actomyosin, actin portion(GO:0042643)
0.1 0.5 GO:0031415 NatA complex(GO:0031415)
0.1 1.4 GO:0005916 fascia adherens(GO:0005916)
0.1 0.7 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.3 GO:0002133 polycystin complex(GO:0002133)
0.1 0.2 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 0.2 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.6 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.4 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 8.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.7 GO:0000322 storage vacuole(GO:0000322)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.4 GO:0061574 ASAP complex(GO:0061574)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.3 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.4 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.7 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.5 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.5 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0071942 XPC complex(GO:0071942)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.8 GO:0071565 nBAF complex(GO:0071565)
0.0 1.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 1.0 GO:0097542 ciliary tip(GO:0097542)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.1 GO:1990597 parallel fiber(GO:1990032) AIP1-IRE1 complex(GO:1990597)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.1 GO:0070938 contractile ring(GO:0070938)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.3 GO:0097440 apical dendrite(GO:0097440)
0.0 0.6 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.0 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 5.1 GO:0001726 ruffle(GO:0001726)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0034709 methylosome(GO:0034709)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 1.8 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 1.3 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.1 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 1.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.0 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.4 1.4 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.3 1.6 GO:0070052 collagen V binding(GO:0070052)
0.3 0.8 GO:0016768 spermine synthase activity(GO:0016768)
0.2 1.3 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.2 0.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 0.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 0.5 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.2 3.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 0.7 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 0.8 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 1.3 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.4 GO:0010736 serum response element binding(GO:0010736)
0.1 0.5 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1 0.7 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.5 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 0.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.5 GO:0017089 glycolipid transporter activity(GO:0017089)
0.1 0.7 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.7 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 2.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.8 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.3 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.3 GO:0005115 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.1 0.2 GO:0032181 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.1 1.6 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.0 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 1.1 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 0.2 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.1 0.7 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 1.8 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.4 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.3 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.2 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.1 0.2 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.2 GO:0086039 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.1 0.2 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.1 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0 0.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.7 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.2 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.1 GO:0017130 poly(C) RNA binding(GO:0017130)
0.0 0.3 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 1.6 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.6 GO:0043559 insulin binding(GO:0043559)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.0 0.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.3 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 1.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0005119 smoothened binding(GO:0005119)
0.0 0.1 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.0 1.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.8 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.3 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.0 GO:0052827 inositol pentakisphosphate phosphatase activity(GO:0052827)
0.0 0.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.6 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 0.3 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 2.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.7 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.2 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.1 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.7 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.6 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.1 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.2 GO:0004386 helicase activity(GO:0004386)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.0 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.0 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.1 3.1 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 4.8 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.4 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.0 1.5 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.6 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 2.4 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 4.1 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.5 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 1.4 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.4 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 0.6 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.5 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.9 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.6 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 2.0 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.2 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.2 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.5 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.0 0.5 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.1 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.6 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.8 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.1 0.9 REACTOME_PROSTANOID_LIGAND_RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 1.3 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.0 1.9 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 3.2 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.0 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 1.5 REACTOME_BOTULINUM_NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 2.5 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME_SIGNALING_BY_FGFR Genes involved in Signaling by FGFR
0.0 0.1 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 1.3 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.9 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.1 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 3.7 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.1 REACTOME_SIGNALING_BY_NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.7 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.9 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.9 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.2 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.2 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.6 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.5 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 1.5 REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.6 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME_SIGNAL_TRANSDUCTION_BY_L1 Genes involved in Signal transduction by L1
0.0 0.5 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.1 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway