Motif ID: EGR1_EGR4

Z-value: 1.709

Transcription factors associated with EGR1_EGR4:

Gene SymbolEntrez IDGene Name
EGR1 ENSG00000120738.7 EGR1
EGR4 ENSG00000135625.6 EGR4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
EGR4hg19_v2_chr2_-_73520667_735208330.333.9e-01Click!
EGR1hg19_v2_chr5_+_137801160_1378011790.166.8e-01Click!


Activity profile for motif EGR1_EGR4.

activity profile for motif EGR1_EGR4


Sorted Z-values histogram for motif EGR1_EGR4

Sorted Z-values for motif EGR1_EGR4



Network of associatons between targets according to the STRING database.



First level regulatory network of EGR1_EGR4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_39873268 3.608 ENST00000397591.2
ENST00000260356.5
 THBS1

thrombospondin 1

chr5_-_176924562 3.581 ENST00000359895.2
ENST00000355572.2
ENST00000355841.2
ENST00000393551.1
ENST00000505074.1
ENST00000356618.4
ENST00000393546.4
 PDLIM7






PDZ and LIM domain 7 (enigma)






chr16_+_3070356 2.905 ENST00000341627.5
ENST00000575124.1
ENST00000575836.1
 TNFRSF12A


tumor necrosis factor receptor superfamily, member 12A


chr16_+_3070313 2.837 ENST00000326577.4
 TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr13_-_41635512 2.392 ENST00000405737.2
 ELF1
E74-like factor 1 (ets domain transcription factor)
chr3_+_11196206 2.366 ENST00000431010.2
 HRH1
histamine receptor H1
chr6_+_86159821 2.209 ENST00000369651.3
 NT5E
5'-nucleotidase, ecto (CD73)
chr22_+_29138013 2.130 ENST00000216027.3
ENST00000398941.2
 HSCB

HscB mitochondrial iron-sulfur cluster co-chaperone

chr6_+_86159765 2.091 ENST00000369646.3
ENST00000257770.3
 NT5E

5'-nucleotidase, ecto (CD73)

chr1_-_94312706 2.068 ENST00000370244.1
 BCAR3
breast cancer anti-estrogen resistance 3
chr1_+_68150744 1.907 ENST00000370986.4
ENST00000370985.3
 GADD45A

growth arrest and DNA-damage-inducible, alpha

chr9_-_130742792 1.798 ENST00000373095.1
 FAM102A
family with sequence similarity 102, member A
chrX_-_154033686 1.783 ENST00000453245.1
ENST00000428488.1
ENST00000369531.1
 MPP1


membrane protein, palmitoylated 1, 55kDa


chr10_+_23728198 1.706 ENST00000376495.3
 OTUD1
OTU domain containing 1
chr20_+_34894247 1.561 ENST00000373913.3
 DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr9_-_101017900 1.560 ENST00000375066.5
 TBC1D2
TBC1 domain family, member 2
chr11_+_66624527 1.549 ENST00000393952.3
 LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr14_-_100842588 1.531 ENST00000556645.1
ENST00000556209.1
ENST00000556504.1
ENST00000556435.1
ENST00000554772.1
ENST00000553581.1
ENST00000553769.2
ENST00000554605.1
ENST00000557722.1
ENST00000553413.1
ENST00000553524.1
ENST00000358655.4
 WARS











tryptophanyl-tRNA synthetase











chr11_-_64546202 1.516 ENST00000377390.3
ENST00000227503.9
ENST00000377394.3
ENST00000422298.2
ENST00000334944.5
 SF1




splicing factor 1




chr17_-_39780819 1.473 ENST00000311208.8
 KRT17
keratin 17
chr17_-_39781054 1.469 ENST00000463128.1
 KRT17
keratin 17
chr10_+_49514698 1.449 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
 MAPK8


mitogen-activated protein kinase 8


chr3_-_66551397 1.413 ENST00000383703.3
 LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chrX_-_154033793 1.411 ENST00000369534.3
ENST00000413259.3
 MPP1

membrane protein, palmitoylated 1, 55kDa

chr6_+_138188551 1.385 ENST00000237289.4
ENST00000433680.1
 TNFAIP3

tumor necrosis factor, alpha-induced protein 3

chr5_-_142784101 1.383 ENST00000503201.1
ENST00000502892.1
 NR3C1

nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

chr17_-_39780634 1.377 ENST00000577817.2
 KRT17
keratin 17
chr5_-_176923846 1.347 ENST00000506537.1
 PDLIM7
PDZ and LIM domain 7 (enigma)
chr11_+_35965531 1.334 ENST00000528989.1
ENST00000524419.1
ENST00000315571.5
 LDLRAD3


low density lipoprotein receptor class A domain containing 3


chr3_+_50192833 1.334 ENST00000426511.1
 SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr6_+_138188378 1.333 ENST00000420009.1
 TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr2_-_98612350 1.327 ENST00000186436.5
 TMEM131
transmembrane protein 131
chr12_-_76425368 1.325 ENST00000602540.1
 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr19_-_44174330 1.319 ENST00000340093.3
 PLAUR
plasminogen activator, urokinase receptor
chr20_-_43977055 1.291 ENST00000372733.3
ENST00000537976.1
 SDC4

syndecan 4

chrX_-_129402857 1.288 ENST00000447817.1
ENST00000370978.4
 ZNF280C

zinc finger protein 280C

chr19_+_45504688 1.274 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
 RELB


v-rel avian reticuloendotheliosis viral oncogene homolog B


chr17_+_79008940 1.262 ENST00000392411.3
ENST00000575989.1
ENST00000321280.7
ENST00000428708.2
ENST00000575712.1
ENST00000575245.1
ENST00000435091.3
ENST00000321300.6
 BAIAP2







BAI1-associated protein 2







chr15_+_74833518 1.254 ENST00000346246.5
 ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr12_-_109125285 1.247 ENST00000552871.1
ENST00000261401.3
 CORO1C

coronin, actin binding protein, 1C

chr19_-_44174305 1.243 ENST00000601723.1
ENST00000339082.3
 PLAUR

plasminogen activator, urokinase receptor

chr2_-_98612379 1.233 ENST00000425805.2
 TMEM131
transmembrane protein 131
chr16_+_1203194 1.229 ENST00000348261.5
ENST00000358590.4
 CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr6_+_12012170 1.216 ENST00000487103.1
 HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr20_+_48429356 1.201 ENST00000361573.2
ENST00000541138.1
ENST00000539601.1
 SLC9A8


solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8


chr5_-_176923803 1.199 ENST00000506161.1
 PDLIM7
PDZ and LIM domain 7 (enigma)
chr11_-_64545941 1.181 ENST00000377387.1
 SF1
splicing factor 1
chrX_+_37545012 1.175 ENST00000378616.3
 XK
X-linked Kx blood group (McLeod syndrome)
chr3_-_126194707 1.142 ENST00000336332.5
ENST00000389709.3
 ZXDC

ZXD family zinc finger C

chr1_+_35246775 1.131 ENST00000373366.2
 GJB3
gap junction protein, beta 3, 31kDa
chr1_-_38273840 1.098 ENST00000373044.2
 YRDC
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr3_-_66551351 1.097 ENST00000273261.3
 LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr15_-_73925575 1.083 ENST00000562924.1
ENST00000563691.1
ENST00000565325.1
ENST00000542234.1
 NPTN



neuroplastin



chr6_+_31783291 1.078 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
 HSPA1A


heat shock 70kDa protein 1A


chr17_+_56160768 1.074 ENST00000579991.2
 DYNLL2
dynein, light chain, LC8-type 2
chr15_-_75017711 1.043 ENST00000567032.1
ENST00000564596.1
ENST00000566503.1
ENST00000395049.4
ENST00000395048.2
ENST00000379727.3
 CYP1A1





cytochrome P450, family 1, subfamily A, polypeptide 1





chr1_+_237205476 1.024 ENST00000366574.2
 RYR2
ryanodine receptor 2 (cardiac)
chr19_-_49371711 1.014 ENST00000355496.5
ENST00000263265.6
 PLEKHA4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr3_+_101546827 1.002 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
 NFKBIZ


nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta


chr2_+_191745535 1.000 ENST00000320717.3
 GLS
glutaminase
chr18_+_3449821 0.984 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
 TGIF1


TGFB-induced factor homeobox 1


chr7_-_148725733 0.976 ENST00000286091.4
 PDIA4
protein disulfide isomerase family A, member 4
chr19_-_39523165 0.975 ENST00000509137.2
ENST00000292853.4
 FBXO27

F-box protein 27

chr1_+_26606608 0.970 ENST00000319041.6
 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr11_-_62313090 0.969 ENST00000528508.1
ENST00000533365.1
 AHNAK

AHNAK nucleoprotein

chr8_+_94929077 0.944 ENST00000297598.4
ENST00000520614.1
 PDP1

pyruvate dehyrogenase phosphatase catalytic subunit 1

chr18_+_3449695 0.928 ENST00000343820.5
 TGIF1
TGFB-induced factor homeobox 1
chr11_-_66104237 0.921 ENST00000530056.1
 RIN1
Ras and Rab interactor 1
chr1_-_9189144 0.920 ENST00000414642.2
 GPR157
G protein-coupled receptor 157
chr20_+_48429233 0.895 ENST00000417961.1
 SLC9A8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr16_+_28834303 0.885 ENST00000340394.8
ENST00000325215.6
ENST00000395547.2
ENST00000336783.4
ENST00000382686.4
ENST00000564304.1
 ATXN2L





ataxin 2-like





chr6_+_31795506 0.878 ENST00000375650.3
 HSPA1B
heat shock 70kDa protein 1B
chr22_-_29137771 0.877 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
 CHEK2









checkpoint kinase 2









chr14_-_53619816 0.866 ENST00000323669.5
ENST00000395606.1
ENST00000357758.3
 DDHD1


DDHD domain containing 1


chr5_+_145583107 0.861 ENST00000506502.1
 RBM27
RNA binding motif protein 27
chr3_-_32612263 0.852 ENST00000432458.2
ENST00000424991.1
ENST00000273130.4
 DYNC1LI1


dynein, cytoplasmic 1, light intermediate chain 1


chr1_-_38471156 0.835 ENST00000373016.3
 FHL3
four and a half LIM domains 3
chr19_+_7985880 0.825 ENST00000597584.1
 SNAPC2
small nuclear RNA activating complex, polypeptide 2, 45kDa
chr19_+_54372877 0.807 ENST00000414489.1
 MYADM
myeloid-associated differentiation marker
chr10_+_104155450 0.799 ENST00000471698.1
ENST00000189444.6
 NFKB2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

chr20_+_44035200 0.788 ENST00000372717.1
ENST00000360981.4
 DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chrX_-_108976449 0.776 ENST00000469857.1
 ACSL4
acyl-CoA synthetase long-chain family member 4
chr16_-_48644061 0.765 ENST00000262384.3
 N4BP1
NEDD4 binding protein 1
chr22_+_31090793 0.758 ENST00000332585.6
ENST00000382310.3
ENST00000446658.2
 OSBP2


oxysterol binding protein 2


chr11_-_122931881 0.755 ENST00000526110.1
ENST00000227378.3
 HSPA8

heat shock 70kDa protein 8

chr11_-_66103932 0.754 ENST00000311320.4
 RIN1
Ras and Rab interactor 1
chr3_-_45267760 0.746 ENST00000503771.1
 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr15_+_52311398 0.740 ENST00000261845.5
 MAPK6
mitogen-activated protein kinase 6
chr19_-_38714847 0.734 ENST00000420980.2
ENST00000355526.4
 DPF1

D4, zinc and double PHD fingers family 1

chr2_-_219433014 0.732 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
 USP37




ubiquitin specific peptidase 37




chr7_-_100026280 0.728 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
 ZCWPW1



zinc finger, CW type with PWWP domain 1



chr4_+_150999418 0.728 ENST00000296550.7
 DCLK2
doublecortin-like kinase 2
chrX_-_48901012 0.724 ENST00000315869.7
 TFE3
transcription factor binding to IGHM enhancer 3
chr2_+_191745560 0.720 ENST00000338435.4
 GLS
glutaminase
chr1_-_33647267 0.718 ENST00000291416.5
 TRIM62
tripartite motif containing 62
chr15_-_73925651 0.714 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
 NPTN


neuroplastin


chr2_-_158732340 0.710 ENST00000539637.1
ENST00000413751.1
ENST00000434821.1
ENST00000424669.1
 ACVR1



activin A receptor, type I



chr1_+_9648921 0.709 ENST00000377376.4
ENST00000340305.5
ENST00000340381.6
 TMEM201


transmembrane protein 201


chr18_+_55102917 0.707 ENST00000491143.2
 ONECUT2
one cut homeobox 2
chr12_+_105724414 0.704 ENST00000443585.1
ENST00000552457.1
ENST00000549893.1
 C12orf75


chromosome 12 open reading frame 75


chr19_-_54693401 0.704 ENST00000338624.6
 MBOAT7
membrane bound O-acyltransferase domain containing 7
chr6_+_12012536 0.701 ENST00000379388.2
 HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr3_+_50192457 0.693 ENST00000414301.1
ENST00000450338.1
 SEMA3F

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F

chr22_+_38597889 0.693 ENST00000338483.2
ENST00000538320.1
ENST00000538999.1
ENST00000441709.1
 MAFF



v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F



chr1_-_9189229 0.688 ENST00000377411.4
 GPR157
G protein-coupled receptor 157
chr16_-_402639 0.680 ENST00000262320.3
 AXIN1
axin 1
chr16_+_69600209 0.678 ENST00000566899.1
 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr9_+_114659046 0.677 ENST00000374279.3
 UGCG
UDP-glucose ceramide glucosyltransferase
chr3_+_50192537 0.669 ENST00000002829.3
 SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr19_-_54693521 0.665 ENST00000391754.1
ENST00000245615.1
ENST00000431666.2
 MBOAT7


membrane bound O-acyltransferase domain containing 7


chr17_+_46184911 0.663 ENST00000580219.1
ENST00000452859.2
ENST00000393405.2
ENST00000439357.2
ENST00000359238.2
 SNX11




sorting nexin 11




chr14_-_69445968 0.662 ENST00000438964.2
 ACTN1
actinin, alpha 1
chr19_+_55999916 0.659 ENST00000587166.1
ENST00000389623.6
 SSC5D

scavenger receptor cysteine rich domain containing (5 domains)

chr9_-_101017862 0.658 ENST00000375064.1
ENST00000342112.5
 TBC1D2

TBC1 domain family, member 2

chr17_-_79791118 0.655 ENST00000576431.1
ENST00000575061.1
ENST00000455127.2
ENST00000572645.1
ENST00000538396.1
ENST00000573478.1
 FAM195B





family with sequence similarity 195, member B





chr3_+_50192499 0.648 ENST00000413852.1
 SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr1_+_156863470 0.647 ENST00000338302.3
ENST00000455314.1
ENST00000292357.7
 PEAR1


platelet endothelial aggregation receptor 1


chr1_+_161494036 0.634 ENST00000309758.4
 HSPA6
heat shock 70kDa protein 6 (HSP70B')
chr11_+_73087309 0.633 ENST00000064780.2
ENST00000545687.1
 RELT

RELT tumor necrosis factor receptor

chrX_-_108976410 0.624 ENST00000504980.1
 ACSL4
acyl-CoA synthetase long-chain family member 4
chr20_+_55966444 0.622 ENST00000356208.5
ENST00000440234.2
 RBM38

RNA binding motif protein 38

chr19_-_40931891 0.621 ENST00000357949.4
 SERTAD1
SERTA domain containing 1
chr8_+_94929110 0.619 ENST00000520728.1
 PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr13_+_110959598 0.616 ENST00000360467.5
 COL4A2
collagen, type IV, alpha 2
chr1_-_85156417 0.613 ENST00000422026.1
 SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr16_+_67062996 0.613 ENST00000561924.2
 CBFB
core-binding factor, beta subunit
chr9_-_110251836 0.612 ENST00000374672.4
 KLF4
Kruppel-like factor 4 (gut)
chr6_-_139308777 0.611 ENST00000529597.1
ENST00000415951.2
ENST00000367663.4
ENST00000409812.2
 REPS1



RALBP1 associated Eps domain containing 1



chr16_-_2185899 0.610 ENST00000262304.4
ENST00000423118.1
 PKD1

polycystic kidney disease 1 (autosomal dominant)

chr16_+_9185450 0.610 ENST00000327827.7
 C16orf72
chromosome 16 open reading frame 72
chr20_+_49348109 0.610 ENST00000396039.1
 PARD6B
par-6 family cell polarity regulator beta
chr4_+_38665810 0.609 ENST00000261438.5
ENST00000514033.1
 KLF3

Kruppel-like factor 3 (basic)

chr2_+_233562015 0.609 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
 GIGYF2














GRB10 interacting GYF protein 2














chr22_+_41777927 0.603 ENST00000266304.4
 TEF
thyrotrophic embryonic factor
chr9_-_77643189 0.602 ENST00000376837.3
 C9orf41
chromosome 9 open reading frame 41
chr17_+_46185111 0.602 ENST00000582104.1
ENST00000584335.1
 SNX11

sorting nexin 11

chr2_-_128145498 0.600 ENST00000409179.2
 MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr12_-_49582593 0.592 ENST00000295766.5
 TUBA1A
tubulin, alpha 1a
chr14_+_66974845 0.589 ENST00000459628.1
 GPHN
gephyrin
chr7_-_752577 0.588 ENST00000544935.1
ENST00000430040.1
ENST00000456696.2
ENST00000406797.1
 PRKAR1B



protein kinase, cAMP-dependent, regulatory, type I, beta



chr6_+_36164487 0.583 ENST00000357641.6
 BRPF3
bromodomain and PHD finger containing, 3
chr19_+_39897453 0.583 ENST00000597629.1
ENST00000248673.3
ENST00000594045.1
ENST00000594442.1
 ZFP36



ZFP36 ring finger protein



chr15_+_41221536 0.577 ENST00000249749.5
 DLL4
delta-like 4 (Drosophila)
chr7_-_92463210 0.568 ENST00000265734.4
 CDK6
cyclin-dependent kinase 6
chr22_-_24181174 0.568 ENST00000318109.7
ENST00000406855.3
ENST00000404056.1
ENST00000476077.1
 DERL3



derlin 3



chr7_-_27213893 0.568 ENST00000283921.4
 HOXA10
homeobox A10
chr9_+_140135665 0.567 ENST00000340384.4
 TUBB4B
tubulin, beta 4B class IVb
chr20_-_17662705 0.565 ENST00000455029.2
 RRBP1
ribosome binding protein 1
chr2_-_129076151 0.565 ENST00000259241.6
 HS6ST1
heparan sulfate 6-O-sulfotransferase 1
chr6_+_134274354 0.561 ENST00000367869.1
 TBPL1
TBP-like 1
chr4_-_25864581 0.560 ENST00000399878.3
 SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr3_-_194207388 0.560 ENST00000457986.1
 ATP13A3
ATPase type 13A3
chr16_+_1359138 0.559 ENST00000325437.5
 UBE2I
ubiquitin-conjugating enzyme E2I
chr9_+_116172958 0.559 ENST00000374165.1
 C9orf43
chromosome 9 open reading frame 43
chr5_-_142783694 0.557 ENST00000394466.2
 NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr5_+_14143728 0.556 ENST00000344204.4
ENST00000537187.1
 TRIO

trio Rho guanine nucleotide exchange factor

chr16_+_50776021 0.552 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
 CYLD


cylindromatosis (turban tumor syndrome)


chr5_-_142784003 0.550 ENST00000416954.2
 NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr2_+_149402553 0.548 ENST00000258484.6
ENST00000409654.1
 EPC2

enhancer of polycomb homolog 2 (Drosophila)

chr17_-_15466742 0.548 ENST00000584811.1
ENST00000419890.2
 TVP23C

trans-golgi network vesicle protein 23 homolog C (S. cerevisiae)

chr22_-_29138386 0.540 ENST00000544772.1
 CHEK2
checkpoint kinase 2
chr19_+_54372693 0.540 ENST00000391768.2
 MYADM
myeloid-associated differentiation marker
chr19_+_54372639 0.535 ENST00000391769.2
 MYADM
myeloid-associated differentiation marker
chr16_+_27325202 0.533 ENST00000395762.2
ENST00000562142.1
ENST00000561742.1
ENST00000543915.2
ENST00000449195.1
ENST00000380922.3
ENST00000563002.1
 IL4R






interleukin 4 receptor






chrX_-_108976521 0.532 ENST00000469796.2
ENST00000502391.1
ENST00000508092.1
ENST00000340800.2
ENST00000348502.6
 ACSL4




acyl-CoA synthetase long-chain family member 4




chr4_+_1003742 0.530 ENST00000398484.2
 FGFRL1
fibroblast growth factor receptor-like 1
chr2_+_187350883 0.529 ENST00000337859.6
 ZC3H15
zinc finger CCCH-type containing 15
chr6_+_134274322 0.529 ENST00000367871.1
ENST00000237264.4
 TBPL1

TBP-like 1

chr1_-_182573514 0.529 ENST00000367558.5
 RGS16
regulator of G-protein signaling 16
chrX_+_21959108 0.528 ENST00000457085.1
 SMS
spermine synthase
chr5_-_172755056 0.527 ENST00000520648.1
 STC2
stanniocalcin 2
chr15_-_41408339 0.524 ENST00000401393.3
 INO80
INO80 complex subunit
chr1_-_2345236 0.522 ENST00000508384.1
 PEX10
peroxisomal biogenesis factor 10
chr19_-_663147 0.522 ENST00000606702.1
 RNF126
ring finger protein 126
chr9_+_116173000 0.520 ENST00000288462.4
 C9orf43
chromosome 9 open reading frame 43
chrX_-_154033661 0.517 ENST00000393531.1
 MPP1
membrane protein, palmitoylated 1, 55kDa
chr13_-_80915059 0.517 ENST00000377104.3
 SPRY2
sprouty homolog 2 (Drosophila)
chrX_+_16185604 0.517 ENST00000400004.2
 MAGEB17
melanoma antigen family B, 17
chr14_+_100842735 0.516 ENST00000554998.1
ENST00000402312.3
ENST00000335290.6
ENST00000554175.1
 WDR25



WD repeat domain 25



chr19_-_1863567 0.515 ENST00000250916.4
 KLF16
Kruppel-like factor 16
chr8_-_102217796 0.513 ENST00000519744.1
ENST00000311212.4
ENST00000521272.1
ENST00000519882.1
 ZNF706



zinc finger protein 706



chr19_-_14629224 0.513 ENST00000254322.2
 DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr16_-_58231782 0.509 ENST00000565188.1
ENST00000262506.3
 CSNK2A2

casein kinase 2, alpha prime polypeptide

chr19_+_1249869 0.507 ENST00000591446.2
 MIDN
midnolin
chr3_-_185826718 0.507 ENST00000413301.1
ENST00000421809.1
 ETV5

ets variant 5

chr3_-_55515202 0.507 ENST00000482079.1
 WNT5A
wingless-type MMTV integration site family, member 5A
chr17_-_41623691 0.506 ENST00000545954.1
 ETV4
ets variant 4
chr14_+_102027688 0.503 ENST00000510508.4
ENST00000359323.3
 DIO3

deiodinase, iodothyronine, type III

chr15_+_72410660 0.502 ENST00000564082.1
 SENP8
SUMO/sentrin specific peptidase family member 8
chr19_-_15443318 0.497 ENST00000360016.5
 BRD4
bromodomain containing 4
chr20_-_17662878 0.497 ENST00000377813.1
ENST00000377807.2
ENST00000360807.4
ENST00000398782.2
 RRBP1



ribosome binding protein 1



chr14_-_69445793 0.496 ENST00000538545.2
ENST00000394419.4
 ACTN1

actinin, alpha 1

chr19_-_55770311 0.493 ENST00000412770.2
 PPP6R1
protein phosphatase 6, regulatory subunit 1
chr7_-_92465868 0.491 ENST00000424848.2
 CDK6
cyclin-dependent kinase 6
chr8_-_102217515 0.490 ENST00000520347.1
ENST00000523922.1
ENST00000520984.1
 ZNF706


zinc finger protein 706


chr15_-_41408409 0.488 ENST00000361937.3
 INO80
INO80 complex subunit
chrX_+_107068959 0.487 ENST00000451923.1
 MID2
midline 2
chr7_-_121036337 0.484 ENST00000426156.1
ENST00000359943.3
ENST00000412653.1
 FAM3C


family with sequence similarity 3, member C


chr7_-_752074 0.484 ENST00000360274.4
 PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr20_+_44034676 0.482 ENST00000372723.3
ENST00000372722.3
 DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0002605 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
1.0 3.0 GO:0070429 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.9 4.3 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.6 0.6 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.6 5.7 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.5 2.5 GO:0032474 otolith morphogenesis(GO:0032474)
0.5 2.0 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.5 2.0 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.5 1.4 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.5 1.4 GO:0071629 cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071629)
0.5 1.4 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.4 1.3 GO:0045210 FasL biosynthetic process(GO:0045210)
0.4 1.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.3 1.0 GO:0043449 cellular alkene metabolic process(GO:0043449) olefin metabolic process(GO:1900673)
0.3 1.0 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.3 1.0 GO:0001743 optic placode formation(GO:0001743)
0.3 2.0 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.3 2.6 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.3 2.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.3 1.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.3 1.2 GO:0031133 regulation of axon diameter(GO:0031133)
0.3 1.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.3 3.3 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.3 1.4 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.3 1.6 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.3 2.9 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.3 0.8 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.3 1.5 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.2 1.7 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 1.0 GO:0061349 chemoattraction of serotonergic neuron axon(GO:0036517) mesodermal to mesenchymal transition involved in gastrulation(GO:0060809) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) negative regulation of cell proliferation in midbrain(GO:1904934) planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation(GO:1904955)
0.2 0.7 GO:0003274 endocardial cushion fusion(GO:0003274)
0.2 2.4 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.2 1.9 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.2 2.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.2 0.7 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.2 0.7 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.2 0.8 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.2 0.4 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.2 0.8 GO:0002268 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.2 0.6 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 1.3 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.2 4.3 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.2 2.6 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.2 0.5 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.2 0.6 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.2 0.6 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.2 0.6 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.2 0.3 GO:0061053 somite development(GO:0061053)
0.2 0.8 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1 0.4 GO:0070376 regulation of ERK5 cascade(GO:0070376) negative regulation of ERK5 cascade(GO:0070377)
0.1 1.2 GO:0035865 cellular response to potassium ion(GO:0035865)
0.1 1.1 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 0.9 GO:0060579 ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.1 0.4 GO:0052553 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) frontal suture morphogenesis(GO:0060364) modulation by virus of host immune response(GO:0075528)
0.1 0.5 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.5 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1 1.5 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1 0.4 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.7 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.4 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 1.4 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.1 0.3 GO:0090340 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of pancreatic juice secretion(GO:0090187) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.1 0.6 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 1.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.3 GO:0060532 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.1 0.4 GO:1901558 response to metformin(GO:1901558) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.3 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.5 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1 0.6 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.4 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.1 GO:0097264 self proteolysis(GO:0097264)
0.1 3.7 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.1 1.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.4 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.2 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
0.1 1.1 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.3 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 0.6 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 2.0 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 0.5 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.1 1.0 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.1 1.0 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 0.4 GO:0061107 cerebellar granular layer morphogenesis(GO:0021683) seminal vesicle development(GO:0061107)
0.1 1.7 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.1 0.9 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.1 0.2 GO:0003192 mitral valve formation(GO:0003192)
0.1 0.9 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 0.3 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.1 0.8 GO:0040031 snRNA modification(GO:0040031)
0.1 0.6 GO:0051697 protein delipidation(GO:0051697)
0.1 1.0 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 0.7 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1 1.5 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.3 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.1 1.0 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.7 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.3 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.1 0.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 2.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.6 GO:0035799 ureter maturation(GO:0035799)
0.1 0.2 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.1 0.3 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.1 0.3 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.4 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.4 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.4 GO:0003383 apical constriction(GO:0003383)
0.1 0.7 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.1 0.3 GO:0019046 release from viral latency(GO:0019046)
0.1 0.7 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.1 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.1 0.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.5 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 0.5 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 0.1 GO:0072218 renal artery morphogenesis(GO:0061441) ascending thin limb development(GO:0072021) metanephric ascending thin limb development(GO:0072218)
0.1 0.4 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.4 GO:0021766 hippocampus development(GO:0021766)
0.1 1.3 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 0.2 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 0.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 1.2 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 1.4 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 0.3 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.1 0.4 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.5 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 1.0 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.2 GO:0072141 renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.1 1.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 0.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.3 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.2 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 0.3 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.9 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.1 0.6 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 0.5 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.1 1.4 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.2 GO:0097069 response to human chorionic gonadotropin(GO:0044752) cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.1 0.2 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.1 0.7 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.4 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.1 0.3 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.8 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 0.4 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 0.2 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 0.2 GO:0036090 cleavage furrow ingression(GO:0036090) positive regulation of late endosome to lysosome transport(GO:1902824)
0.1 0.2 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.0 0.2 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.0 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.3 GO:0072708 response to sorbitol(GO:0072708)
0.0 0.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 1.4 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 1.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.7 GO:0016926 protein desumoylation(GO:0016926)
0.0 1.7 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.4 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.0 GO:0099541 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.0 1.3 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 1.3 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.4 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.0 0.9 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:0043633 polyadenylation-dependent RNA catabolic process(GO:0043633) polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.0 0.0 GO:1901503 glycerol ether metabolic process(GO:0006662) ether lipid biosynthetic process(GO:0008611) ether lipid metabolic process(GO:0046485) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.2 GO:0009052 D-ribose metabolic process(GO:0006014) pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.7 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.4 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.7 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.2 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.4 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.5 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0 0.1 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.4 GO:0046836 glycolipid transport(GO:0046836)
0.0 0.1 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0003335 corneocyte development(GO:0003335)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.2 GO:0032796 uropod organization(GO:0032796)
0.0 1.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.5 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.0 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 1.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.3 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.6 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.2 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.0 GO:0003186 tricuspid valve morphogenesis(GO:0003186)
0.0 0.1 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.0 0.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 3.0 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.3 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.5 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.2 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.2 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.4 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.2 GO:0060992 response to fungicide(GO:0060992)
0.0 0.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.4 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.3 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.4 GO:2000482 regulation of interleukin-8 secretion(GO:2000482)
0.0 0.5 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861) ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.5 GO:0060539 diaphragm development(GO:0060539)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.3 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.1 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.0 0.7 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.3 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.0 0.1 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.0 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.0 0.3 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 1.0 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 0.2 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.6 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.0 GO:0090241 negative regulation of histone H4 acetylation(GO:0090241)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.2 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.2 GO:0043921 modulation by host of viral transcription(GO:0043921) modulation of transcription in other organism involved in symbiotic interaction(GO:0052312) modulation by host of symbiont transcription(GO:0052472)
0.0 0.4 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.2 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.5 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0043129 surfactant homeostasis(GO:0043129)
0.0 0.8 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.5 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.6 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.3 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 2.2 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.2 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.0 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.0 0.5 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.5 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.5 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.2 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.0 2.6 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 1.5 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.3 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.2 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.2 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.3 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.2 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.2 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.4 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.3 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.1 GO:0060556 regulation of vitamin D biosynthetic process(GO:0060556)
0.0 0.1 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.1 GO:0015993 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 1.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.1 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.4 GO:0007567 parturition(GO:0007567)
0.0 0.0 GO:0072071 mesangial cell differentiation(GO:0072007) glomerular mesangial cell differentiation(GO:0072008) kidney interstitial fibroblast differentiation(GO:0072071) pericyte cell differentiation(GO:1904238)
0.0 0.1 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.4 GO:0043586 tongue development(GO:0043586)
0.0 0.5 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.0 GO:0090188 negative regulation of pancreatic juice secretion(GO:0090188)
0.0 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0061015 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.2 GO:0040016 embryonic cleavage(GO:0040016)
0.0 1.1 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.0 0.3 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.2 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0060444 branching involved in mammary gland duct morphogenesis(GO:0060444)
0.0 0.5 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.8 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.3 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.3 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.5 GO:0001649 osteoblast differentiation(GO:0001649)
0.0 0.6 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.2 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.0 0.8 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:0007097 nuclear migration(GO:0007097)
0.0 0.3 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.3 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.1 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.1 GO:0071926 endocannabinoid signaling pathway(GO:0071926)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.0 GO:2001016 positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.2 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.7 GO:0045453 bone resorption(GO:0045453)
0.0 0.1 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.3 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.1 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.3 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.0 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:0046016 positive regulation of transcription by glucose(GO:0046016)
0.0 0.7 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.8 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.0 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415) negative regulation of histone H3-K4 methylation(GO:0051572)
0.0 0.3 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.1 GO:0010498 proteasomal protein catabolic process(GO:0010498)
0.0 0.3 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.5 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.6 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.0 GO:1904674 regulation of somatic stem cell population maintenance(GO:1904672) positive regulation of somatic stem cell population maintenance(GO:1904674)
0.0 0.1 GO:0010608 posttranscriptional regulation of gene expression(GO:0010608)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.6 GO:0005577 fibrinogen complex(GO:0005577)
0.2 0.7 GO:0048179 activin receptor complex(GO:0048179)
0.2 0.8 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.2 1.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 0.5 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.1 2.6 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.7 GO:0002133 polycystin complex(GO:0002133)
0.1 1.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.4 GO:0098843 postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)
0.1 0.4 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 1.9 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.8 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 1.9 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.5 GO:0071942 XPC complex(GO:0071942)
0.1 1.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.9 GO:0061574 ASAP complex(GO:0061574)
0.1 0.9 GO:0016589 NURF complex(GO:0016589)
0.1 0.7 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 1.4 GO:0005916 fascia adherens(GO:0005916)
0.1 0.6 GO:1990635 proximal dendrite(GO:1990635)
0.1 1.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 1.2 GO:0016600 flotillin complex(GO:0016600)
0.1 0.5 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 1.2 GO:0097433 dense body(GO:0097433)
0.1 0.6 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 1.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 0.2 GO:0032302 MutSbeta complex(GO:0032302)
0.1 0.4 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 1.9 GO:0071565 nBAF complex(GO:0071565)
0.1 0.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 1.1 GO:0005922 connexon complex(GO:0005922)
0.1 0.4 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.2 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.3 GO:0031417 NatC complex(GO:0031417)
0.1 8.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.6 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 1.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:0097196 Shu complex(GO:0097196)
0.0 0.7 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 1.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.5 GO:0034709 methylosome(GO:0034709)
0.0 0.6 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 2.2 GO:0043034 costamere(GO:0043034)
0.0 0.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0071564 npBAF complex(GO:0071564)
0.0 2.0 GO:0032420 stereocilium(GO:0032420)
0.0 1.0 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.4 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.4 GO:0001939 female pronucleus(GO:0001939)
0.0 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.4 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.5 GO:0070578 RISC-loading complex(GO:0070578)
0.0 4.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 1.0 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 1.2 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 8.7 GO:0001726 ruffle(GO:0001726)
0.0 0.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0070701 mucus layer(GO:0070701)
0.0 0.9 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 1.3 GO:0097542 ciliary tip(GO:0097542)
0.0 1.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.8 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.4 GO:0045178 basal part of cell(GO:0045178)
0.0 0.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.8 GO:0097440 apical dendrite(GO:0097440)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.4 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.0 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 1.5 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 2.7 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.5 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.2 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 1.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.9 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.7 GO:0035770 ribonucleoprotein granule(GO:0035770)
0.0 1.9 GO:0016605 PML body(GO:0016605)
0.0 2.5 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.3 GO:0097610 cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.0 0.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.7 3.6 GO:0070052 collagen V binding(GO:0070052)
0.7 4.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.6 1.9 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.5 1.4 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.4 1.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.4 1.1 GO:0016768 spermine synthase activity(GO:0016768)
0.4 2.6 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.4 1.8 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.4 3.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.4 1.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.3 2.8 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.3 1.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.3 0.8 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.3 1.5 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.2 4.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 1.0 GO:0005115 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.2 1.6 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.2 1.7 GO:0004359 glutaminase activity(GO:0004359)
0.2 1.0 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.2 0.8 GO:0004913 interleukin-4 receptor activity(GO:0004913)
0.2 4.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 2.1 GO:0004969 histamine receptor activity(GO:0004969)
0.2 0.5 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.2 2.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.2 1.0 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.2 3.3 GO:0045499 chemorepellent activity(GO:0045499)
0.2 2.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.4 GO:0043398 HLH domain binding(GO:0043398)
0.1 0.4 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 1.8 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 0.5 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.1 0.4 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.1 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.7 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.3 GO:0010736 serum response element binding(GO:0010736)
0.1 0.3 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.3 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 0.4 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.6 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 0.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.6 GO:0050692 DBD domain binding(GO:0050692)
0.1 1.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 1.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.4 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.4 GO:0034584 piRNA binding(GO:0034584)
0.1 0.2 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 1.2 GO:0005243 gap junction channel activity(GO:0005243)
0.1 3.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.3 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.4 GO:0017089 glycolipid transporter activity(GO:0017089)
0.1 0.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.4 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.2 GO:0032181 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.1 0.2 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 0.2 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.1 2.5 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 3.2 GO:0001671 ATPase activator activity(GO:0001671)
0.1 2.5 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.5 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.2 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.2 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.2 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.2 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.1 0.5 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.2 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.2 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.0 1.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.9 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.3 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 1.6 GO:0030275 LRR domain binding(GO:0030275)
0.0 1.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 1.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 1.2 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.2 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.3 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 1.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.6 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.3 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.3 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.1 GO:0017130 poly(C) RNA binding(GO:0017130)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 1.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 1.0 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.9 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 1.4 GO:0017166 vinculin binding(GO:0017166)
0.0 1.0 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.5 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.5 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 1.1 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 1.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.9 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.4 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.5 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 0.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.7 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0019808 polyamine binding(GO:0019808)
0.0 0.5 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 1.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.1 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.4 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 1.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0 1.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 2.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.3 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.9 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0097027 anaphase-promoting complex binding(GO:0010997) ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 1.4 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0016859 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 3.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.4 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.0 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.6 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.7 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 1.1 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 3.5 GO:0001047 core promoter binding(GO:0001047)
0.0 0.0 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.0 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 1.2 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.5 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0008483 transaminase activity(GO:0008483)
0.0 0.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.2 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.0 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.0 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.3 GO:0042393 histone binding(GO:0042393)
0.0 0.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.9 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.2 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.1 0.4 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.1 7.2 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.1 4.1 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 2.5 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor
0.1 0.1 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.1 0.5 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 5.0 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.1 3.8 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 1.7 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 3.1 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 2.6 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 5.2 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 8.7 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.6 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.4 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 1.9 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID_ALK2_PATHWAY ALK2 signaling events
0.0 3.1 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 2.5 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 3.7 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 4.6 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 1.1 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 0.4 ST_GAQ_PATHWAY G alpha q Pathway
0.0 0.5 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.6 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.1 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 0.3 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.2 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.7 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.0 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.2 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.8 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.5 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.7 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.3 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.3 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 0.2 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.1 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.6 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.7 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.2 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.1 2.3 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 2.5 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.8 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.1 0.8 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 3.1 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 4.5 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 2.1 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.1 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 1.2 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.4 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.0 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.0 0.8 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 4.7 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.6 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS Genes involved in Prolonged ERK activation events
0.0 0.4 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.4 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME_INFLUENZA_LIFE_CYCLE Genes involved in Influenza Life Cycle
0.0 1.3 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.5 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.3 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.4 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.6 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 5.3 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.1 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.4 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.5 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 1.4 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.3 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.8 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 1.3 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.6 REACTOME_SIGNAL_TRANSDUCTION_BY_L1 Genes involved in Signal transduction by L1
0.0 0.7 REACTOME_SIGNALING_BY_WNT Genes involved in Signaling by Wnt
0.0 0.7 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.9 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.8 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.2 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.2 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 1.8 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.5 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 1.3 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.8 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.6 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 0.5 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.9 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.7 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.1 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.5 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.8 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.7 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 1.0 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.0 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.0 0.3 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.9 REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.0 0.3 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.1 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.3 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.3 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.2 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis