Motif ID: EBF3

Z-value: 0.815


Transcription factors associated with EBF3:

Gene SymbolEntrez IDGene Name
EBF3 ENSG00000108001.9 EBF3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
EBF3hg19_v2_chr10_-_131762105_131762105-0.531.4e-01Click!


Activity profile for motif EBF3.

activity profile for motif EBF3


Sorted Z-values histogram for motif EBF3

Sorted Z-values for motif EBF3



Network of associatons between targets according to the STRING database.



First level regulatory network of EBF3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_1051455 0.984 ENST00000379339.1
ENST00000480643.1
ENST00000434641.1
ENST00000421241.2
C1orf159



chromosome 1 open reading frame 159



chr11_-_67120974 0.964 ENST00000539074.1
ENST00000312419.3
POLD4

polymerase (DNA-directed), delta 4, accessory subunit

chr16_+_3068393 0.919 ENST00000573001.1
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr16_-_31076332 0.639 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
ZNF668


zinc finger protein 668


chr1_+_35220613 0.633 ENST00000338513.1
GJB5
gap junction protein, beta 5, 31.1kDa
chr11_-_9482010 0.590 ENST00000596206.1
AC132192.1
LOC644656 protein; Uncharacterized protein
chr16_-_30798492 0.569 ENST00000262525.4
ZNF629
zinc finger protein 629
chr7_-_92747269 0.534 ENST00000446617.1
ENST00000379958.2
SAMD9

sterile alpha motif domain containing 9

chr17_+_75315654 0.497 ENST00000590595.1
SEPT9
septin 9
chr7_+_75932863 0.496 ENST00000429938.1
HSPB1
heat shock 27kDa protein 1
chr16_+_81772633 0.481 ENST00000565054.1
ENST00000566191.1
ENST00000565272.1
ENST00000563954.1
PLCG2
RP11-960L18.1


phospholipase C, gamma 2 (phosphatidylinositol-specific)
RP11-960L18.1


chr1_+_100503643 0.478 ENST00000370152.3
HIAT1
hippocampus abundant transcript 1
chr16_+_89988259 0.476 ENST00000554444.1
ENST00000556565.1
TUBB3

Tubulin beta-3 chain

chr6_-_41908428 0.465 ENST00000505064.1
CCND3
cyclin D3
chr1_-_26197744 0.452 ENST00000374296.3
PAQR7
progestin and adipoQ receptor family member VII
chr9_-_139581848 0.450 ENST00000538402.1
ENST00000371694.3
AGPAT2

1-acylglycerol-3-phosphate O-acyltransferase 2

chr16_-_85784718 0.442 ENST00000602766.1
C16orf74
chromosome 16 open reading frame 74
chr7_-_45018686 0.425 ENST00000258787.7
MYO1G
myosin IG
chr19_-_1650666 0.415 ENST00000588136.1
TCF3
transcription factor 3
chr7_-_100183742 0.393 ENST00000310300.6
LRCH4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr9_-_139581875 0.383 ENST00000371696.2
AGPAT2
1-acylglycerol-3-phosphate O-acyltransferase 2
chr8_+_22446763 0.383 ENST00000450780.2
ENST00000430850.2
ENST00000447849.1
AC037459.4


Uncharacterized protein


chr19_+_49403562 0.377 ENST00000407032.1
ENST00000452087.1
ENST00000411700.1
NUCB1


nucleobindin 1


chr17_-_73874654 0.375 ENST00000254816.2
TRIM47
tripartite motif containing 47
chr7_+_100464760 0.374 ENST00000200457.4
TRIP6
thyroid hormone receptor interactor 6
chr3_+_159481464 0.368 ENST00000467377.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr16_-_85784634 0.363 ENST00000284245.4
ENST00000602914.1
C16orf74

chromosome 16 open reading frame 74

chr19_+_54369434 0.361 ENST00000421337.1
MYADM
myeloid-associated differentiation marker
chr1_-_159915386 0.360 ENST00000361509.3
ENST00000368094.1
IGSF9

immunoglobulin superfamily, member 9

chrX_+_49019061 0.359 ENST00000376339.1
ENST00000425661.2
ENST00000458388.1
ENST00000412696.2
MAGIX



MAGI family member, X-linked



chr9_-_138987115 0.345 ENST00000277554.2
NACC2
NACC family member 2, BEN and BTB (POZ) domain containing
chr11_-_66104237 0.345 ENST00000530056.1
RIN1
Ras and Rab interactor 1
chr1_-_165414414 0.337 ENST00000359842.5
RXRG
retinoid X receptor, gamma
chrX_+_152990302 0.334 ENST00000218104.3
ABCD1
ATP-binding cassette, sub-family D (ALD), member 1
chr16_-_85784557 0.331 ENST00000602675.1
C16orf74
chromosome 16 open reading frame 74
chr8_-_19459993 0.329 ENST00000454498.2
ENST00000520003.1
CSGALNACT1

chondroitin sulfate N-acetylgalactosaminyltransferase 1

chr11_+_57227981 0.320 ENST00000335099.3
RTN4RL2
reticulon 4 receptor-like 2
chr16_-_29478016 0.318 ENST00000549858.1
ENST00000551411.1
RP11-345J4.3

Uncharacterized protein

chr19_+_50433476 0.313 ENST00000596658.1
ATF5
activating transcription factor 5
chr19_-_4722705 0.311 ENST00000598360.1
DPP9
dipeptidyl-peptidase 9
chr8_+_145582217 0.311 ENST00000530047.1
ENST00000527078.1
SLC52A2

solute carrier family 52 (riboflavin transporter), member 2

chr8_+_145582231 0.305 ENST00000526338.1
ENST00000402965.1
ENST00000534725.1
ENST00000532887.1
ENST00000329994.2
SLC52A2




solute carrier family 52 (riboflavin transporter), member 2




chr19_+_33668509 0.300 ENST00000592484.1
LRP3
low density lipoprotein receptor-related protein 3
chr17_-_80023401 0.297 ENST00000354321.7
ENST00000306796.5
DUS1L

dihydrouridine synthase 1-like (S. cerevisiae)

chr22_+_29702572 0.292 ENST00000407647.2
ENST00000416823.1
ENST00000428622.1
GAS2L1


growth arrest-specific 2 like 1


chr16_+_30662050 0.287 ENST00000568754.1
PRR14
proline rich 14
chr19_+_49128209 0.283 ENST00000599748.1
ENST00000443164.1
ENST00000599029.1
SPHK2


sphingosine kinase 2


chr8_+_145582633 0.278 ENST00000540505.1
SLC52A2
solute carrier family 52 (riboflavin transporter), member 2
chr20_-_62203808 0.278 ENST00000467148.1
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr19_+_14063278 0.275 ENST00000254337.6
DCAF15
DDB1 and CUL4 associated factor 15
chr6_-_30654977 0.275 ENST00000399199.3
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr16_+_30662085 0.268 ENST00000569864.1
PRR14
proline rich 14
chr11_-_1782625 0.266 ENST00000438213.1
CTSD
cathepsin D
chr3_+_42695176 0.265 ENST00000232974.6
ENST00000457842.3
ZBTB47

zinc finger and BTB domain containing 47

chr11_+_75273246 0.263 ENST00000526397.1
ENST00000529643.1
ENST00000525492.1
ENST00000530284.1
ENST00000532356.1
ENST00000524558.1
SERPINH1





serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)





chr17_-_74023291 0.263 ENST00000586740.1
EVPL
envoplakin
chr1_+_3388181 0.260 ENST00000418137.1
ENST00000413250.2
ARHGEF16

Rho guanine nucleotide exchange factor (GEF) 16

chr19_+_39904168 0.258 ENST00000438123.1
ENST00000409797.2
ENST00000451354.2
PLEKHG2


pleckstrin homology domain containing, family G (with RhoGef domain) member 2


chr17_+_77021702 0.257 ENST00000392445.2
ENST00000354124.3
C1QTNF1

C1q and tumor necrosis factor related protein 1

chr9_-_140095186 0.256 ENST00000409012.4
TPRN
taperin
chr17_-_74023474 0.254 ENST00000301607.3
EVPL
envoplakin
chr19_-_4722780 0.253 ENST00000600621.1
DPP9
dipeptidyl-peptidase 9
chr19_+_50270219 0.252 ENST00000354293.5
ENST00000359032.5
AP2A1

adaptor-related protein complex 2, alpha 1 subunit

chr11_+_22646739 0.248 ENST00000428556.2
AC103801.2
AC103801.2
chr19_+_18043810 0.248 ENST00000445755.2
CCDC124
coiled-coil domain containing 124
chr17_-_73901494 0.247 ENST00000309352.3
MRPL38
mitochondrial ribosomal protein L38
chr8_+_22409193 0.247 ENST00000240123.7
SORBS3
sorbin and SH3 domain containing 3
chr3_-_98619999 0.239 ENST00000449482.1
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr5_+_176237478 0.238 ENST00000329542.4
UNC5A
unc-5 homolog A (C. elegans)
chr7_-_1015198 0.235 ENST00000344111.3
COX19
cytochrome c oxidase assembly homolog 19 (S. cerevisiae)
chr11_+_65408273 0.234 ENST00000394227.3
SIPA1
signal-induced proliferation-associated 1
chr15_+_90728145 0.233 ENST00000561085.1
ENST00000379122.3
ENST00000332496.6
SEMA4B


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B


chr10_-_73533255 0.233 ENST00000394957.3
C10orf54
chromosome 10 open reading frame 54
chr7_-_73133959 0.233 ENST00000395155.3
ENST00000395154.3
ENST00000222812.3
ENST00000395156.3
STX1A



syntaxin 1A (brain)



chr19_+_50180317 0.233 ENST00000534465.1
PRMT1
protein arginine methyltransferase 1
chr15_-_86338134 0.230 ENST00000337975.5
KLHL25
kelch-like family member 25
chr7_-_100881109 0.230 ENST00000308344.5
CLDN15
claudin 15
chr11_+_75273101 0.230 ENST00000533603.1
ENST00000358171.3
ENST00000526242.1
SERPINH1


serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)


chr19_-_40772221 0.229 ENST00000441941.2
ENST00000580747.1
AKT2

v-akt murine thymoma viral oncogene homolog 2

chr17_-_80023659 0.227 ENST00000578907.1
ENST00000577907.1
ENST00000578176.1
ENST00000582529.1
DUS1L



dihydrouridine synthase 1-like (S. cerevisiae)



chr17_+_73452545 0.225 ENST00000314256.7
KIAA0195
KIAA0195
chr17_-_73839792 0.224 ENST00000590762.1
UNC13D
unc-13 homolog D (C. elegans)
chr11_-_65381643 0.222 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
MAP3K11


mitogen-activated protein kinase kinase kinase 11


chr6_+_32936942 0.221 ENST00000496118.2
BRD2
bromodomain containing 2
chr3_-_52273098 0.219 ENST00000597542.1
ENST00000499914.2
ENST00000305533.5
TLR9
TWF2

toll-like receptor 9
twinfilin actin-binding protein 2

chr16_+_31085714 0.219 ENST00000300850.5
ENST00000564189.1
ENST00000428260.1
ZNF646


zinc finger protein 646


chr1_-_16563641 0.218 ENST00000375599.3
RSG1
REM2 and RAB-like small GTPase 1
chr17_+_38465441 0.218 ENST00000577646.1
ENST00000254066.5
RARA

retinoic acid receptor, alpha

chr12_-_51663728 0.218 ENST00000603864.1
ENST00000605426.1
SMAGP

small cell adhesion glycoprotein

chr17_+_77020224 0.217 ENST00000339142.2
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr18_+_56806701 0.215 ENST00000587834.1
SEC11C
SEC11 homolog C (S. cerevisiae)
chr19_+_984313 0.213 ENST00000251289.5
ENST00000587001.2
ENST00000607440.1
WDR18


WD repeat domain 18


chr1_-_44497024 0.213 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
SLC6A9


solute carrier family 6 (neurotransmitter transporter, glycine), member 9


chr15_-_86338100 0.211 ENST00000536947.1
KLHL25
kelch-like family member 25
chr8_+_22436635 0.208 ENST00000452226.1
ENST00000397760.4
ENST00000339162.7
ENST00000397761.2
PDLIM2



PDZ and LIM domain 2 (mystique)



chr7_-_27187393 0.207 ENST00000222728.3
HOXA6
homeobox A6
chr5_+_133861339 0.207 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
PHF15


jade family PHD finger 2


chr8_+_120428546 0.206 ENST00000259526.3
NOV
nephroblastoma overexpressed
chr17_+_45973516 0.206 ENST00000376741.4
SP2
Sp2 transcription factor
chr14_+_105952648 0.204 ENST00000330233.7
CRIP1
cysteine-rich protein 1 (intestinal)
chr19_+_45909893 0.203 ENST00000592852.1
ENST00000589804.1
ENST00000590794.1
CD3EAP


CD3e molecule, epsilon associated protein


chr5_+_6766004 0.201 ENST00000506093.1
RP11-332J15.3
RP11-332J15.3
chr12_+_48152774 0.200 ENST00000549243.1
SLC48A1
solute carrier family 48 (heme transporter), member 1
chr8_+_22436248 0.200 ENST00000308354.7
PDLIM2
PDZ and LIM domain 2 (mystique)
chr1_-_2345236 0.199 ENST00000508384.1
PEX10
peroxisomal biogenesis factor 10
chr2_-_97523721 0.199 ENST00000393537.4
ANKRD39
ankyrin repeat domain 39
chr12_+_113860160 0.196 ENST00000553248.1
ENST00000345635.4
ENST00000547802.1
SDSL


serine dehydratase-like


chr7_-_100881041 0.194 ENST00000412417.1
ENST00000414035.1
CLDN15

claudin 15

chr15_+_84841242 0.190 ENST00000558195.1
RP11-182J1.16
ubiquitin-conjugating enzyme E2Q family member 2-like
chr15_-_40633101 0.189 ENST00000559313.1
C15orf52
chromosome 15 open reading frame 52
chr19_+_41107249 0.187 ENST00000396819.3
LTBP4
latent transforming growth factor beta binding protein 4
chr11_+_35222629 0.187 ENST00000526553.1
CD44
CD44 molecule (Indian blood group)
chr16_+_2083265 0.186 ENST00000565855.1
ENST00000566198.1
SLC9A3R2

solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2

chr17_+_73606766 0.185 ENST00000578462.1
MYO15B
myosin XVB pseudogene
chr5_+_177027101 0.185 ENST00000029410.5
ENST00000510761.1
ENST00000505468.1
B4GALT7


xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7


chrX_+_48367338 0.183 ENST00000359882.4
ENST00000537758.1
ENST00000367574.4
ENST00000355961.4
ENST00000489940.1
ENST00000361988.3
PORCN





porcupine homolog (Drosophila)





chr19_+_13049413 0.183 ENST00000316448.5
ENST00000588454.1
CALR

calreticulin

chr1_-_154943212 0.182 ENST00000368445.5
ENST00000448116.2
ENST00000368449.4
SHC1


SHC (Src homology 2 domain containing) transforming protein 1


chr17_+_77020325 0.179 ENST00000311661.4
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr11_+_65480222 0.179 ENST00000534681.1
KAT5
K(lysine) acetyltransferase 5
chr12_+_7282795 0.179 ENST00000266546.6
CLSTN3
calsyntenin 3
chr1_+_153330322 0.177 ENST00000368738.3
S100A9
S100 calcium binding protein A9
chr18_+_56807096 0.176 ENST00000588875.1
SEC11C
SEC11 homolog C (S. cerevisiae)
chr17_+_39975455 0.175 ENST00000455106.1
FKBP10
FK506 binding protein 10, 65 kDa
chr16_+_30671223 0.175 ENST00000568722.1
FBRS
fibrosin
chr9_+_139221880 0.174 ENST00000392945.3
ENST00000440944.1
GPSM1

G-protein signaling modulator 1

chr1_-_1310530 0.173 ENST00000338370.3
ENST00000321751.5
ENST00000378853.3
AURKAIP1


aurora kinase A interacting protein 1


chr14_+_105953246 0.173 ENST00000392531.3
CRIP1
cysteine-rich protein 1 (intestinal)
chr20_-_30795511 0.173 ENST00000246229.4
PLAGL2
pleiomorphic adenoma gene-like 2
chr1_-_247495045 0.172 ENST00000294753.4
ENST00000366498.2
ZNF496

zinc finger protein 496

chr1_+_110577229 0.172 ENST00000369795.3
ENST00000369794.2
STRIP1

striatin interacting protein 1

chr2_+_226265364 0.172 ENST00000272907.6
NYAP2
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr1_-_117210290 0.172 ENST00000369483.1
ENST00000369486.3
IGSF3

immunoglobulin superfamily, member 3

chr17_+_39975544 0.169 ENST00000544340.1
FKBP10
FK506 binding protein 10, 65 kDa
chr17_+_73539339 0.168 ENST00000581713.1
LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr17_-_78194147 0.167 ENST00000534910.1
ENST00000326317.6
SGSH

N-sulfoglucosamine sulfohydrolase

chr14_+_105953204 0.167 ENST00000409393.2
CRIP1
cysteine-rich protein 1 (intestinal)
chr9_-_35619539 0.166 ENST00000396757.1
CD72
CD72 molecule
chr17_+_78194261 0.164 ENST00000572725.1
SLC26A11
solute carrier family 26 (anion exchanger), member 11
chr2_-_75796837 0.164 ENST00000233712.1
EVA1A
eva-1 homolog A (C. elegans)
chr3_+_159481791 0.164 ENST00000460298.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr16_+_30662184 0.163 ENST00000300835.4
PRR14
proline rich 14
chr1_+_100810575 0.163 ENST00000542213.1
CDC14A
cell division cycle 14A
chr7_+_48128194 0.163 ENST00000416681.1
ENST00000331803.4
ENST00000432131.1
UPP1


uridine phosphorylase 1


chr1_-_154164534 0.163 ENST00000271850.7
ENST00000368530.2
TPM3

tropomyosin 3

chr19_+_7600584 0.162 ENST00000600737.1
PNPLA6
patatin-like phospholipase domain containing 6
chr9_+_134103496 0.162 ENST00000498010.1
ENST00000476004.1
ENST00000528406.1
NUP214


nucleoporin 214kDa


chr2_+_134877740 0.160 ENST00000409645.1
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr9_-_95298314 0.160 ENST00000344604.5
ENST00000375540.1
ECM2

extracellular matrix protein 2, female organ and adipocyte specific

chr22_+_42834029 0.160 ENST00000428765.1
CTA-126B4.7
CTA-126B4.7
chr12_-_48214345 0.159 ENST00000433685.1
ENST00000447463.1
ENST00000427332.2
HDAC7


histone deacetylase 7


chr20_-_44516256 0.158 ENST00000372519.3
SPATA25
spermatogenesis associated 25
chr2_+_219264762 0.157 ENST00000452977.1
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr19_+_50180507 0.157 ENST00000454376.2
ENST00000524771.1
PRMT1

protein arginine methyltransferase 1

chr1_-_153585539 0.154 ENST00000368706.4
S100A16
S100 calcium binding protein A16
chr14_-_102704783 0.153 ENST00000522534.1
MOK
MOK protein kinase
chr12_+_53443963 0.153 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1


tensin like C1 domain containing phosphatase (tensin 2)


chr9_+_136325089 0.152 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
CACFD1


calcium channel flower domain containing 1


chr11_-_64545941 0.150 ENST00000377387.1
SF1
splicing factor 1
chr6_+_43457317 0.150 ENST00000438588.2
TJAP1
tight junction associated protein 1 (peripheral)
chr12_+_53443680 0.150 ENST00000314250.6
ENST00000451358.1
TENC1

tensin like C1 domain containing phosphatase (tensin 2)

chr14_-_69350920 0.149 ENST00000553290.1
ACTN1
actinin, alpha 1
chr14_-_105635090 0.149 ENST00000331782.3
ENST00000347004.2
JAG2

jagged 2

chr11_+_64950801 0.149 ENST00000526468.1
CAPN1
calpain 1, (mu/I) large subunit
chr17_+_7308172 0.148 ENST00000575301.1
NLGN2
neuroligin 2
chr16_-_30381580 0.147 ENST00000409939.3
TBC1D10B
TBC1 domain family, member 10B
chr3_+_193853927 0.145 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr17_+_79071365 0.144 ENST00000576756.1
BAIAP2
BAI1-associated protein 2
chr1_+_16010779 0.144 ENST00000375799.3
ENST00000375793.2
PLEKHM2

pleckstrin homology domain containing, family M (with RUN domain) member 2

chr14_+_24630465 0.142 ENST00000557894.1
ENST00000559284.1
ENST00000560275.1
IRF9


interferon regulatory factor 9


chr11_-_104893863 0.142 ENST00000260315.3
ENST00000526056.1
ENST00000531367.1
ENST00000456094.1
ENST00000444749.2
ENST00000393141.2
ENST00000418434.1
ENST00000393139.2
CASP5







caspase 5, apoptosis-related cysteine peptidase







chr19_+_54369608 0.142 ENST00000336967.3
MYADM
myeloid-associated differentiation marker
chr17_-_1928621 0.141 ENST00000331238.6
RTN4RL1
reticulon 4 receptor-like 1
chr10_-_135171510 0.141 ENST00000278025.4
ENST00000368552.3
FUOM

fucose mutarotase

chr17_-_1395954 0.139 ENST00000359786.5
MYO1C
myosin IC
chr11_-_72852320 0.138 ENST00000422375.1
FCHSD2
FCH and double SH3 domains 2
chr1_+_14925173 0.136 ENST00000376030.2
ENST00000503743.1
ENST00000422387.2
KAZN


kazrin, periplakin interacting protein


chr1_+_36023035 0.134 ENST00000373253.3
NCDN
neurochondrin
chr8_-_145641864 0.134 ENST00000276833.5
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr19_-_7293942 0.134 ENST00000341500.5
ENST00000302850.5
INSR

insulin receptor

chr1_-_27693349 0.134 ENST00000374040.3
ENST00000357582.2
ENST00000493901.1
MAP3K6


mitogen-activated protein kinase kinase kinase 6


chr17_+_77020146 0.132 ENST00000579760.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr1_+_895930 0.132 ENST00000338591.3
KLHL17
kelch-like family member 17
chr7_+_73507409 0.130 ENST00000538333.3
LIMK1
LIM domain kinase 1
chr5_+_148651469 0.130 ENST00000515000.1
AFAP1L1
actin filament associated protein 1-like 1
chr17_-_79881408 0.128 ENST00000392366.3
MAFG
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr9_+_116343192 0.127 ENST00000471324.2
RGS3
regulator of G-protein signaling 3
chr17_-_78194124 0.127 ENST00000570427.1
ENST00000570923.1
SGSH

N-sulfoglucosamine sulfohydrolase

chr19_+_50180409 0.126 ENST00000391851.4
PRMT1
protein arginine methyltransferase 1
chr19_-_40324255 0.125 ENST00000593685.1
ENST00000600611.1
DYRK1B

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B

chr13_-_24895566 0.124 ENST00000422229.2
AL359736.1
protein PCOTH isoform 1
chr9_+_136325149 0.123 ENST00000542192.1
CACFD1
calcium channel flower domain containing 1
chr17_+_78193443 0.122 ENST00000577155.1
SLC26A11
solute carrier family 26 (anion exchanger), member 11
chr11_-_72432950 0.120 ENST00000426523.1
ENST00000429686.1
ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr12_-_94673956 0.120 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr2_+_27301435 0.119 ENST00000380320.4
EMILIN1
elastin microfibril interfacer 1
chr17_+_73472575 0.118 ENST00000375248.5
KIAA0195
KIAA0195
chr1_+_206623784 0.118 ENST00000426388.1
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr15_+_90544532 0.116 ENST00000268154.4
ZNF710
zinc finger protein 710
chr16_-_28506840 0.114 ENST00000569430.1
CLN3
ceroid-lipofuscinosis, neuronal 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0032218 riboflavin transport(GO:0032218)
0.2 0.6 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.5 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 0.5 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.1 0.5 GO:0002316 follicular B cell differentiation(GO:0002316)
0.1 0.8 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.9 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.3 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.1 0.3 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.2 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 0.5 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653) positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1 0.2 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.3 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.1 0.4 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.3 GO:0006218 uridine catabolic process(GO:0006218)
0.1 0.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.5 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.2 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.2 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 0.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.3 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.2 GO:0002432 granuloma formation(GO:0002432)
0.1 0.2 GO:1901895 regulation of interleukin-18 production(GO:0032661) positive regulation of interferon-alpha biosynthetic process(GO:0045356) negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.1 0.5 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 0.4 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.5 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 0.2 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.3 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.3 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.3 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.2 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.2 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.8 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 0.2 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.1 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 0.1 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.4 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 1.0 GO:0006266 DNA ligation(GO:0006266)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.1 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.4 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.1 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.0 0.2 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:2000977 regulation of forebrain neuron differentiation(GO:2000977)
0.0 0.2 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.4 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.1 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.1 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.0 0.1 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.1 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.3 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.2 GO:0060180 female mating behavior(GO:0060180)
0.0 0.1 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.0 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.0 0.0 GO:0019085 early viral transcription(GO:0019085)
0.0 0.1 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.1 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682) metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.0 0.4 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.1 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.4 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.5 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.1 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.5 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.0 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.0 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.2 GO:0007030 Golgi organization(GO:0007030)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.4 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.4 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.2 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.4 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.5 GO:0034709 methylosome(GO:0034709)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:0044301 climbing fiber(GO:0044301)
0.0 0.2 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0042022 interleukin-12 receptor complex(GO:0042022)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0005608 laminin-3 complex(GO:0005608)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.0 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.5 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 0.4 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.3 GO:0016826 N-sulfoglucosamine sulfohydrolase activity(GO:0016250) hydrolase activity, acting on acid sulfur-nitrogen bonds(GO:0016826)
0.1 0.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.2 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.1 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.2 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.1 0.2 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.5 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.3 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.5 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.3 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.2 GO:0042806 fucose binding(GO:0042806)
0.0 0.6 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.5 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 1.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0016517 interleukin-12 receptor activity(GO:0016517)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.0 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.0 0.5 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.7 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.1 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.6 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.4 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.8 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.4 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.2 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters