Motif ID: E2F8

Z-value: 0.535


Transcription factors associated with E2F8:

Gene SymbolEntrez IDGene Name
E2F8 ENSG00000129173.8 E2F8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E2F8hg19_v2_chr11_-_19263145_19263176-0.206.0e-01Click!


Activity profile for motif E2F8.

activity profile for motif E2F8


Sorted Z-values histogram for motif E2F8

Sorted Z-values for motif E2F8



Network of associatons between targets according to the STRING database.



First level regulatory network of E2F8

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_153330322 0.777 ENST00000368738.3
S100A9
S100 calcium binding protein A9
chr12_-_8815215 0.717 ENST00000544889.1
ENST00000543369.1
MFAP5

microfibrillar associated protein 5

chr12_-_8815299 0.589 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr17_-_39928106 0.562 ENST00000540235.1
JUP
junction plakoglobin
chr1_+_70876926 0.430 ENST00000370938.3
ENST00000346806.2
CTH

cystathionase (cystathionine gamma-lyase)

chr22_+_35796108 0.396 ENST00000382011.5
ENST00000416905.1
MCM5

minichromosome maintenance complex component 5

chr22_+_35796056 0.389 ENST00000216122.4
MCM5
minichromosome maintenance complex component 5
chr16_-_30134266 0.361 ENST00000484663.1
ENST00000478356.1
MAPK3

mitogen-activated protein kinase 3

chr18_-_47813940 0.357 ENST00000586837.1
ENST00000412036.2
ENST00000589940.1
CXXC1


CXXC finger protein 1


chr18_-_47814032 0.355 ENST00000589548.1
ENST00000591474.1
CXXC1

CXXC finger protein 1

chr2_+_233385173 0.344 ENST00000449534.2
PRSS56
protease, serine, 56
chr14_-_100841670 0.297 ENST00000557297.1
ENST00000555813.1
ENST00000557135.1
ENST00000556698.1
ENST00000554509.1
ENST00000555410.1
WARS





tryptophanyl-tRNA synthetase





chr16_-_30134441 0.287 ENST00000395200.1
MAPK3
mitogen-activated protein kinase 3
chr17_+_48503519 0.281 ENST00000300441.4
ENST00000541920.1
ENST00000506582.1
ENST00000504392.1
ENST00000427954.2
ACSF2




acyl-CoA synthetase family member 2




chr12_-_6772303 0.279 ENST00000396807.4
ENST00000446105.2
ENST00000341550.4
ING4


inhibitor of growth family, member 4


chr1_+_70876891 0.271 ENST00000411986.2
CTH
cystathionase (cystathionine gamma-lyase)
chr12_-_6772249 0.266 ENST00000467678.1
ENST00000493873.1
ENST00000423703.2
ENST00000412586.2
ENST00000444704.2
ING4




inhibitor of growth family, member 4




chr6_-_166401402 0.261 ENST00000581850.1
ENST00000444465.1
LINC00473

long intergenic non-protein coding RNA 473

chr6_-_166401442 0.257 ENST00000584179.1
LINC00473
long intergenic non-protein coding RNA 473
chr17_+_27895045 0.243 ENST00000580183.2
ENST00000578749.1
ENST00000582829.2
TP53I13


tumor protein p53 inducible protein 13


chr11_+_9595180 0.231 ENST00000450114.2
WEE1
WEE1 G2 checkpoint kinase
chr17_+_48503603 0.227 ENST00000502667.1
ACSF2
acyl-CoA synthetase family member 2
chr9_-_131486367 0.220 ENST00000372663.4
ENST00000406904.2
ENST00000452105.1
ENST00000372672.2
ENST00000372667.5
ZDHHC12




zinc finger, DHHC-type containing 12




chr4_+_1714548 0.216 ENST00000605571.1
RP11-572O17.1
RP11-572O17.1
chr11_+_17298297 0.212 ENST00000529010.1
NUCB2
nucleobindin 2
chr17_+_37894570 0.212 ENST00000394211.3
GRB7
growth factor receptor-bound protein 7
chr11_+_17298255 0.210 ENST00000531172.1
ENST00000533738.2
ENST00000323688.6
NUCB2


nucleobindin 2


chr16_+_11439286 0.207 ENST00000312499.5
ENST00000576027.1
RMI2

RecQ mediated genome instability 2

chr2_-_24346218 0.196 ENST00000436622.1
ENST00000313213.4
PFN4

profilin family, member 4

chr2_+_130939235 0.192 ENST00000425361.1
ENST00000457492.1
MZT2B

mitotic spindle organizing protein 2B

chr8_+_128426535 0.183 ENST00000465342.2
POU5F1B
POU class 5 homeobox 1B
chr6_+_160693591 0.172 ENST00000419196.1
RP1-276N6.2
RP1-276N6.2
chr7_+_26331541 0.169 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
SNX10


sorting nexin 10


chr16_-_75150665 0.164 ENST00000300051.4
ENST00000450168.2
LDHD

lactate dehydrogenase D

chr11_+_111473108 0.163 ENST00000304987.3
SIK2
salt-inducible kinase 2
chr1_+_156024552 0.158 ENST00000368304.5
ENST00000368302.3
LAMTOR2

late endosomal/lysosomal adaptor, MAPK and MTOR activator 2

chr19_+_41103063 0.154 ENST00000308370.7
LTBP4
latent transforming growth factor beta binding protein 4
chr22_-_20104700 0.152 ENST00000439169.2
ENST00000445045.1
ENST00000404751.3
ENST00000252136.7
ENST00000403707.3
TRMT2A




tRNA methyltransferase 2 homolog A (S. cerevisiae)




chr3_+_127317705 0.149 ENST00000480910.1
MCM2
minichromosome maintenance complex component 2
chr3_-_49466686 0.146 ENST00000273598.3
ENST00000436744.2
NICN1

nicolin 1

chr17_+_21030260 0.145 ENST00000579303.1
DHRS7B
dehydrogenase/reductase (SDR family) member 7B
chr14_-_74551096 0.144 ENST00000350259.4
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr1_+_156024525 0.143 ENST00000368305.4
LAMTOR2
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr1_+_46859933 0.141 ENST00000243167.8
FAAH
fatty acid amide hydrolase
chr1_+_197871740 0.138 ENST00000367393.3
C1orf53
chromosome 1 open reading frame 53
chr9_-_35079911 0.135 ENST00000448890.1
FANCG
Fanconi anemia, complementation group G
chr17_+_6915730 0.123 ENST00000548577.1
RNASEK
ribonuclease, RNase K
chr17_+_6915798 0.123 ENST00000402093.1
RNASEK
ribonuclease, RNase K
chr5_+_66124590 0.122 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
MAST4


microtubule associated serine/threonine kinase family member 4


chr5_+_34757309 0.122 ENST00000397449.1
RAI14
retinoic acid induced 14
chr19_+_49403562 0.119 ENST00000407032.1
ENST00000452087.1
ENST00000411700.1
NUCB1


nucleobindin 1


chr11_-_327537 0.117 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr2_-_136633940 0.117 ENST00000264156.2
MCM6
minichromosome maintenance complex component 6
chr17_-_43128943 0.116 ENST00000588499.1
ENST00000593094.1
DCAKD

dephospho-CoA kinase domain containing

chr14_-_74551172 0.114 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr1_+_197871854 0.113 ENST00000436652.1
C1orf53
chromosome 1 open reading frame 53
chr19_-_19249255 0.113 ENST00000587583.2
ENST00000450333.2
ENST00000587096.1
ENST00000162044.9
ENST00000592369.1
ENST00000587915.1
TMEM161A





transmembrane protein 161A





chr6_+_27107053 0.112 ENST00000354348.2
HIST1H4I
histone cluster 1, H4i
chr17_+_6915902 0.112 ENST00000570898.1
ENST00000552842.1
RNASEK

ribonuclease, RNase K

chr17_-_9479128 0.108 ENST00000574431.1
STX8
syntaxin 8
chr21_-_45682099 0.102 ENST00000270172.3
ENST00000418993.1
DNMT3L

DNA (cytosine-5-)-methyltransferase 3-like

chr12_-_102455846 0.101 ENST00000545679.1
CCDC53
coiled-coil domain containing 53
chr17_+_39975455 0.100 ENST00000455106.1
FKBP10
FK506 binding protein 10, 65 kDa
chr7_+_75932863 0.099 ENST00000429938.1
HSPB1
heat shock 27kDa protein 1
chr11_+_65029233 0.099 ENST00000265465.3
POLA2
polymerase (DNA directed), alpha 2, accessory subunit
chr1_+_154975110 0.098 ENST00000535420.1
ENST00000368426.3
ZBTB7B

zinc finger and BTB domain containing 7B

chr17_-_5389477 0.097 ENST00000572834.1
ENST00000570848.1
ENST00000571971.1
ENST00000158771.4
DERL2



derlin 2



chr14_-_61190754 0.095 ENST00000216513.4
SIX4
SIX homeobox 4
chr7_-_100026280 0.093 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
ZCWPW1



zinc finger, CW type with PWWP domain 1



chr17_+_39975544 0.092 ENST00000544340.1
FKBP10
FK506 binding protein 10, 65 kDa
chr19_+_4402659 0.089 ENST00000301280.5
ENST00000585854.1
CHAF1A

chromatin assembly factor 1, subunit A (p150)

chr1_+_43637996 0.088 ENST00000528956.1
ENST00000529956.1
WDR65

WD repeat domain 65

chr2_+_230787201 0.088 ENST00000283946.3
FBXO36
F-box protein 36
chr19_+_50887585 0.088 ENST00000440232.2
ENST00000601098.1
ENST00000599857.1
ENST00000593887.1
POLD1



polymerase (DNA directed), delta 1, catalytic subunit



chr14_-_51135005 0.087 ENST00000556735.1
SAV1
salvador homolog 1 (Drosophila)
chr19_+_36132631 0.082 ENST00000379026.2
ENST00000379023.4
ENST00000402764.2
ENST00000479824.1
ETV2



ets variant 2



chr14_+_55595762 0.082 ENST00000254301.9
LGALS3
lectin, galactoside-binding, soluble, 3
chr5_-_145483932 0.082 ENST00000311450.4
PLAC8L1
PLAC8-like 1
chr10_-_74385811 0.082 ENST00000603011.1
ENST00000401998.3
ENST00000361114.5
ENST00000604238.1
MICU1



mitochondrial calcium uptake 1



chr19_+_11546153 0.079 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
PRKCSH


protein kinase C substrate 80K-H


chr2_+_230787213 0.078 ENST00000409992.1
FBXO36
F-box protein 36
chr22_-_19974616 0.078 ENST00000344269.3
ENST00000401994.1
ENST00000406522.1
ARVCF


armadillo repeat gene deleted in velocardiofacial syndrome


chr2_+_109745655 0.077 ENST00000418513.1
SH3RF3
SH3 domain containing ring finger 3
chr9_+_139690784 0.077 ENST00000338005.6
KIAA1984
coiled-coil domain containing 183
chr17_+_54671047 0.077 ENST00000332822.4
NOG
noggin
chr12_-_102455902 0.076 ENST00000240079.6
CCDC53
coiled-coil domain containing 53
chr17_+_57642886 0.075 ENST00000251241.4
ENST00000451169.2
ENST00000425628.3
ENST00000584385.1
ENST00000580030.1
DHX40




DEAH (Asp-Glu-Ala-His) box polypeptide 40




chr3_-_157251383 0.074 ENST00000487753.1
ENST00000489602.1
ENST00000461299.1
ENST00000479987.1
VEPH1



ventricular zone expressed PH domain-containing 1



chr22_+_42086547 0.073 ENST00000402966.1
C22orf46
chromosome 22 open reading frame 46
chr7_+_116593536 0.073 ENST00000417919.1
ST7
suppression of tumorigenicity 7
chr14_-_24898731 0.073 ENST00000267406.6
CBLN3
cerebellin 3 precursor
chr19_-_46146946 0.071 ENST00000536630.1
EML2
echinoderm microtubule associated protein like 2
chr14_-_50065882 0.071 ENST00000539688.1
AL139099.1
Full-length cDNA clone CS0DK012YO09 of HeLa cells of Homo sapiens (human); Uncharacterized protein
chr19_+_57874835 0.071 ENST00000282282.3
ENST00000543226.1
ENST00000596755.1
ENST00000597658.1
ZNF547
TRAPPC2P1

AC003002.4
zinc finger protein 547
trafficking protein particle complex 2 pseudogene 1

Uncharacterized protein
chr11_+_809647 0.070 ENST00000321153.4
RPLP2
ribosomal protein, large, P2
chr15_+_44119159 0.069 ENST00000263795.6
ENST00000381246.2
ENST00000452115.1
WDR76


WD repeat domain 76


chr8_+_48873453 0.069 ENST00000523944.1
MCM4
minichromosome maintenance complex component 4
chr12_-_10321754 0.069 ENST00000539518.1
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr1_-_36916066 0.069 ENST00000315643.9
OSCP1
organic solute carrier partner 1
chrX_-_153707545 0.068 ENST00000357360.4
LAGE3
L antigen family, member 3
chr17_-_6915616 0.068 ENST00000575889.1
AC027763.2
Uncharacterized protein
chr19_+_2270283 0.067 ENST00000588673.2
OAZ1
ornithine decarboxylase antizyme 1
chr8_+_48873479 0.067 ENST00000262105.2
MCM4
minichromosome maintenance complex component 4
chr17_+_38444115 0.067 ENST00000580824.1
ENST00000577249.1
CDC6

cell division cycle 6

chr7_+_4815238 0.066 ENST00000348624.4
ENST00000401897.1
AP5Z1

adaptor-related protein complex 5, zeta 1 subunit

chr7_-_56174161 0.066 ENST00000395422.3
CHCHD2
coiled-coil-helix-coiled-coil-helix domain containing 2
chr2_-_113993020 0.065 ENST00000465084.1
PAX8
paired box 8
chr10_-_74385876 0.065 ENST00000398761.4
MICU1
mitochondrial calcium uptake 1
chr22_+_20105259 0.065 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RANBP1



RAN binding protein 1



chr7_-_152373216 0.064 ENST00000359321.1
XRCC2
X-ray repair complementing defective repair in Chinese hamster cells 2
chr1_-_6295975 0.064 ENST00000343813.5
ENST00000362035.3
ICMT

isoprenylcysteine carboxyl methyltransferase

chr5_-_16465901 0.064 ENST00000308683.2
ZNF622
zinc finger protein 622
chr14_+_105155925 0.063 ENST00000330634.7
ENST00000398337.4
ENST00000392634.4
INF2


inverted formin, FH2 and WH2 domain containing


chr11_-_13484713 0.063 ENST00000526841.1
ENST00000529708.1
ENST00000278174.5
ENST00000528120.1
BTBD10



BTB (POZ) domain containing 10



chr11_+_809961 0.062 ENST00000530797.1
RPLP2
ribosomal protein, large, P2
chr2_-_152146385 0.062 ENST00000414946.1
ENST00000243346.5
NMI

N-myc (and STAT) interactor

chr1_-_36916011 0.062 ENST00000356637.5
ENST00000354267.3
ENST00000235532.5
OSCP1


organic solute carrier partner 1


chr22_+_19467261 0.062 ENST00000455750.1
ENST00000437685.2
ENST00000263201.1
ENST00000404724.3
CDC45



cell division cycle 45



chr1_-_28241226 0.061 ENST00000373912.3
ENST00000373909.3
RPA2

replication protein A2, 32kDa

chr17_-_15165854 0.061 ENST00000395936.1
ENST00000395938.2
PMP22

peripheral myelin protein 22

chr17_+_73028676 0.061 ENST00000581589.1
KCTD2
potassium channel tetramerization domain containing 2
chr1_-_6453399 0.060 ENST00000608083.1
ACOT7
acyl-CoA thioesterase 7
chr17_-_6915646 0.059 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
AC027763.2




Uncharacterized protein




chr12_+_56324756 0.059 ENST00000331886.5
ENST00000555090.1
DGKA

diacylglycerol kinase, alpha 80kDa

chr12_-_57146095 0.059 ENST00000550770.1
ENST00000338193.6
PRIM1

primase, DNA, polypeptide 1 (49kDa)

chr11_+_125496124 0.058 ENST00000533778.2
ENST00000534070.1
CHEK1

checkpoint kinase 1

chr6_-_32157947 0.057 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr11_+_2397402 0.056 ENST00000475945.2
CD81
CD81 molecule
chr1_+_205473720 0.056 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
CDK18


cyclin-dependent kinase 18


chr18_+_72922710 0.055 ENST00000322038.5
TSHZ1
teashirt zinc finger homeobox 1
chr6_-_33290580 0.055 ENST00000446511.1
ENST00000446403.1
ENST00000414083.2
ENST00000266000.6
ENST00000374542.5
DAXX




death-domain associated protein




chr19_+_11546440 0.053 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
PRKCSH





protein kinase C substrate 80K-H





chr11_-_108369101 0.053 ENST00000323468.5
KDELC2
KDEL (Lys-Asp-Glu-Leu) containing 2
chr22_-_36877629 0.053 ENST00000416967.1
TXN2
thioredoxin 2
chr21_+_37477164 0.051 ENST00000422473.1
AP000688.29
AP000688.29
chr5_-_180242534 0.051 ENST00000333055.3
ENST00000513431.1
MGAT1

mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase

chrX_-_153707246 0.051 ENST00000407062.1
LAGE3
L antigen family, member 3
chr4_-_1714037 0.050 ENST00000488267.1
ENST00000429429.2
ENST00000480936.1
SLBP


stem-loop binding protein


chr7_+_116593433 0.050 ENST00000323984.3
ENST00000393449.1
ST7

suppression of tumorigenicity 7

chr12_+_56324933 0.049 ENST00000549629.1
ENST00000555218.1
DGKA

diacylglycerol kinase, alpha 80kDa

chr11_+_2397418 0.049 ENST00000530648.1
CD81
CD81 molecule
chr9_-_74675521 0.049 ENST00000377024.3
C9orf57
chromosome 9 open reading frame 57
chr17_-_73127353 0.049 ENST00000580423.1
ENST00000578337.1
ENST00000582160.1
NT5C


5', 3'-nucleotidase, cytosolic


chr16_-_31147020 0.049 ENST00000568261.1
ENST00000567797.1
ENST00000317508.6
PRSS8


protease, serine, 8


chr14_+_64854958 0.049 ENST00000555709.2
ENST00000554739.1
ENST00000554768.1
ENST00000216605.8
MTHFD1



methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase



chr1_-_28241024 0.049 ENST00000313433.7
ENST00000444045.1
RPA2

replication protein A2, 32kDa

chr19_+_49977466 0.048 ENST00000596435.1
ENST00000344019.3
ENST00000597551.1
ENST00000204637.2
ENST00000600429.1
FLT3LG




fms-related tyrosine kinase 3 ligand




chr12_+_123459127 0.048 ENST00000397389.2
ENST00000538755.1
ENST00000536150.1
ENST00000545056.1
ENST00000545612.1
ENST00000538628.1
ENST00000545317.1
OGFOD2






2-oxoglutarate and iron-dependent oxygenase domain containing 2






chr8_+_69242957 0.047 ENST00000518698.1
ENST00000539993.1
C8orf34

chromosome 8 open reading frame 34

chrX_-_129299847 0.047 ENST00000319908.3
ENST00000287295.3
AIFM1

apoptosis-inducing factor, mitochondrion-associated, 1

chrX_-_48216101 0.046 ENST00000298396.2
ENST00000376893.3
SSX3

synovial sarcoma, X breakpoint 3

chr17_-_59940830 0.045 ENST00000259008.2
BRIP1
BRCA1 interacting protein C-terminal helicase 1
chr17_-_2615031 0.045 ENST00000576885.1
ENST00000574426.2
CLUH

clustered mitochondria (cluA/CLU1) homolog

chr10_+_35416090 0.044 ENST00000354759.3
CREM
cAMP responsive element modulator
chr12_-_110939870 0.044 ENST00000447578.2
ENST00000546588.1
ENST00000360579.7
ENST00000549970.1
ENST00000549578.1
VPS29




vacuolar protein sorting 29 homolog (S. cerevisiae)




chr17_-_15165825 0.043 ENST00000426385.3
PMP22
peripheral myelin protein 22
chr9_-_140484917 0.043 ENST00000298585.2
ZMYND19
zinc finger, MYND-type containing 19
chr1_+_7844312 0.043 ENST00000377541.1
PER3
period circadian clock 3
chr7_+_116593568 0.043 ENST00000446490.1
ST7
suppression of tumorigenicity 7
chr2_-_20251744 0.043 ENST00000175091.4
LAPTM4A
lysosomal protein transmembrane 4 alpha
chr4_-_57844989 0.042 ENST00000264230.4
NOA1
nitric oxide associated 1
chr1_+_17248418 0.042 ENST00000375541.5
CROCC
ciliary rootlet coiled-coil, rootletin
chrX_-_55020511 0.042 ENST00000375006.3
ENST00000374992.2
PFKFB1

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

chr1_-_110052302 0.042 ENST00000369864.4
ENST00000369862.1
AMIGO1

adhesion molecule with Ig-like domain 1

chr16_+_67198683 0.041 ENST00000517685.1
ENST00000521374.1
ENST00000584272.1
HSF4


heat shock transcription factor 4


chr14_-_23388338 0.041 ENST00000555209.1
ENST00000554256.1
ENST00000557403.1
ENST00000557549.1
ENST00000555676.1
ENST00000557571.1
ENST00000557464.1
ENST00000554618.1
ENST00000556862.1
ENST00000555722.1
ENST00000346528.5
ENST00000542016.2
ENST00000399922.2
ENST00000557227.1
ENST00000359890.3
RBM23














RNA binding motif protein 23














chr4_-_140223614 0.041 ENST00000394223.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr19_+_19144384 0.040 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
ARMC6










armadillo repeat containing 6










chr8_+_145065705 0.040 ENST00000533044.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr19_+_37464440 0.040 ENST00000455817.1
ENST00000588596.1
ZNF568

zinc finger protein 568

chr5_-_58882219 0.040 ENST00000505453.1
ENST00000360047.5
PDE4D

phosphodiesterase 4D, cAMP-specific

chr17_-_61819121 0.039 ENST00000245865.5
ENST00000375840.4
ENST00000582137.1
ENST00000579549.1
ENST00000582030.1
ENST00000584110.1
ENST00000580288.1
ENST00000336174.6
ENST00000579340.1
ENST00000580338.1
STRADA









STE20-related kinase adaptor alpha









chr3_+_70048881 0.038 ENST00000483525.1
RP11-460N16.1
RP11-460N16.1
chr13_-_19755975 0.038 ENST00000400113.3
TUBA3C
tubulin, alpha 3c
chr1_-_89458287 0.038 ENST00000370485.2
CCBL2
cysteine conjugate-beta lyase 2
chr16_-_28937027 0.038 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr5_+_31532373 0.037 ENST00000325366.9
ENST00000355907.3
ENST00000507818.2
C5orf22


chromosome 5 open reading frame 22


chr5_-_180242576 0.037 ENST00000514438.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr17_+_29815013 0.037 ENST00000394744.2
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr19_+_16296191 0.037 ENST00000589852.1
ENST00000263384.7
ENST00000588367.1
ENST00000587351.1
FAM32A



family with sequence similarity 32, member A



chr1_+_33283043 0.036 ENST00000373476.1
ENST00000373475.5
ENST00000529027.1
ENST00000398243.3
S100PBP



S100P binding protein



chr15_+_44719996 0.036 ENST00000559793.1
ENST00000558968.1
CTDSPL2

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2

chr7_+_100136811 0.036 ENST00000300176.4
ENST00000262935.4
AGFG2

ArfGAP with FG repeats 2

chr4_-_1713977 0.036 ENST00000318386.4
SLBP
stem-loop binding protein
chr9_+_130186653 0.034 ENST00000342483.5
ENST00000543471.1
ZNF79

zinc finger protein 79

chr4_+_108910870 0.034 ENST00000403312.1
ENST00000603302.1
ENST00000309522.3
HADH


hydroxyacyl-CoA dehydrogenase


chr7_-_56118981 0.034 ENST00000419984.2
ENST00000413218.1
ENST00000424596.1
PSPH


phosphoserine phosphatase


chr3_+_127317066 0.034 ENST00000265056.7
MCM2
minichromosome maintenance complex component 2
chr12_+_56522001 0.034 ENST00000267113.4
ENST00000541590.1
ESYT1

extended synaptotagmin-like protein 1

chr6_-_149806105 0.033 ENST00000389942.5
ENST00000416573.2
ENST00000542614.1
ENST00000409806.3
ZC3H12D



zinc finger CCCH-type containing 12D



chr10_-_104178857 0.033 ENST00000020673.5
PSD
pleckstrin and Sec7 domain containing
chr1_-_111682662 0.033 ENST00000286692.4
DRAM2
DNA-damage regulated autophagy modulator 2
chr12_-_16761007 0.032 ENST00000354662.1
ENST00000441439.2
LMO3

LIM domain only 3 (rhombotin-like 2)

chr15_+_44719394 0.032 ENST00000260327.4
ENST00000396780.1
CTDSPL2

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2

chr10_-_12237836 0.032 ENST00000444732.1
ENST00000378940.3
NUDT5

nudix (nucleoside diphosphate linked moiety X)-type motif 5

chr17_-_2614927 0.032 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr12_+_56521840 0.032 ENST00000394048.5
ESYT1
extended synaptotagmin-like protein 1
chr4_-_113558014 0.032 ENST00000503172.1
ENST00000505019.1
ENST00000309071.5
C4orf21


chromosome 4 open reading frame 21


chr3_+_197677047 0.031 ENST00000448864.1
RPL35A
ribosomal protein L35a
chr6_+_26251835 0.031 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.2 0.7 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.2 0.6 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.1 0.5 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 0.3 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.6 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.3 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.2 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.0 0.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 1.3 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.1 GO:2000612 pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) thyroid-stimulating hormone secretion(GO:0070460) kidney field specification(GO:0072004) DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0 0.1 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.1 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.1 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.0 0.1 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0 0.1 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677) negative regulation of immunological synapse formation(GO:2000521)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.0 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.1 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.0 0.0 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 0.1 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.0 GO:0060629 regulation of homologous chromosome segregation(GO:0060629)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.6 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.0 GO:1903450 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.0 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.1 1.2 GO:0042555 MCM complex(GO:0042555)
0.1 1.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.6 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 0.8 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.2 GO:0004458 D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.0 0.3 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.5 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.1 GO:0004040 amidase activity(GO:0004040)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.1 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.1 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 0.1 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.0 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 1.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.3 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.8 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.6 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.4 REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND Genes involved in Processive synthesis on the lagging strand
0.0 0.3 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.7 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions