Motif ID: DUXA

Z-value: 0.631


Transcription factors associated with DUXA:

Gene SymbolEntrez IDGene Name
DUXA ENSG00000258873.2 DUXA

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
DUXAhg19_v2_chr19_-_57678811_576788110.462.1e-01Click!


Activity profile for motif DUXA.

activity profile for motif DUXA


Sorted Z-values histogram for motif DUXA

Sorted Z-values for motif DUXA



Network of associatons between targets according to the STRING database.



First level regulatory network of DUXA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_19796381 1.227 ENST00000524029.1
ENST00000522701.1
ENST00000311322.8
LPL


lipoprotein lipase


chr7_+_135777671 0.584 ENST00000445293.2
ENST00000435996.1
AC009784.3

AC009784.3

chr6_-_32920794 0.524 ENST00000395305.3
ENST00000395303.3
ENST00000374843.4
ENST00000429234.1
HLA-DMA


XXbac-BPG181M17.5
major histocompatibility complex, class II, DM alpha


Uncharacterized protein
chr12_-_114211474 0.454 ENST00000550905.1
ENST00000547963.1
RP11-438N16.1

RP11-438N16.1

chr17_+_76494911 0.373 ENST00000598378.1
DNAH17-AS1
DNAH17 antisense RNA 1
chr22_+_31518938 0.357 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J






inositol polyphosphate-5-phosphatase J






chr9_-_23779367 0.347 ENST00000440102.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr9_-_5833027 0.301 ENST00000339450.5
ERMP1
endoplasmic reticulum metallopeptidase 1
chr4_-_112993808 0.286 ENST00000511219.1
RP11-269F21.3
RP11-269F21.3
chr18_+_44812072 0.285 ENST00000598649.1
ENST00000586905.2
CTD-2130O13.1

CTD-2130O13.1

chr6_-_134639235 0.278 ENST00000533224.1
SGK1
serum/glucocorticoid regulated kinase 1
chr12_-_114211444 0.261 ENST00000510694.2
ENST00000550223.1
RP11-438N16.1

RP11-438N16.1

chr7_-_137028534 0.256 ENST00000348225.2
PTN
pleiotrophin
chr4_-_110651143 0.248 ENST00000243501.5
PLA2G12A
phospholipase A2, group XIIA
chr7_-_137028498 0.234 ENST00000393083.2
PTN
pleiotrophin
chrX_+_64708615 0.233 ENST00000338957.4
ENST00000423889.3
ZC3H12B

zinc finger CCCH-type containing 12B

chr1_-_12908578 0.229 ENST00000317869.6
HNRNPCL1
heterogeneous nuclear ribonucleoprotein C-like 1
chrX_+_154444643 0.229 ENST00000286428.5
VBP1
von Hippel-Lindau binding protein 1
chr10_-_61900762 0.217 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr7_-_99277610 0.202 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
CYP3A5



cytochrome P450, family 3, subfamily A, polypeptide 5



chr6_-_75953484 0.199 ENST00000472311.2
ENST00000460985.1
ENST00000377978.3
ENST00000509698.1
ENST00000230459.4
ENST00000370089.2
COX7A2





cytochrome c oxidase subunit VIIa polypeptide 2 (liver)





chr7_+_135611542 0.195 ENST00000416501.1
AC015987.2
AC015987.2
chr2_-_231989808 0.187 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr15_+_101402041 0.181 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
RP11-66B24.1


RP11-66B24.1


chr11_+_28129795 0.180 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
METTL15



methyltransferase like 15



chr18_-_10787140 0.176 ENST00000383408.2
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr21_+_18811205 0.174 ENST00000440664.1
C21orf37
chromosome 21 open reading frame 37
chr12_-_54653313 0.174 ENST00000550411.1
ENST00000439541.2
CBX5

chromobox homolog 5

chr12_-_51422017 0.173 ENST00000394904.3
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chrX_+_69501943 0.171 ENST00000509895.1
ENST00000374473.2
ENST00000276066.4
RAB41


RAB41, member RAS oncogene family


chr11_+_114270752 0.169 ENST00000540163.1
RBM7
RNA binding motif protein 7
chr2_-_175629164 0.167 ENST00000409323.1
ENST00000261007.5
ENST00000348749.5
CHRNA1


cholinergic receptor, nicotinic, alpha 1 (muscle)


chr16_+_69221028 0.163 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr2_-_24299308 0.162 ENST00000233468.4
SF3B14
Pre-mRNA branch site protein p14
chr16_+_53412368 0.162 ENST00000565189.1
RP11-44F14.2
RP11-44F14.2
chr3_-_58419537 0.162 ENST00000474765.1
ENST00000485460.1
ENST00000302746.6
ENST00000383714.4
PDHB



pyruvate dehydrogenase (lipoamide) beta



chr19_+_52932435 0.158 ENST00000301085.4
ZNF534
zinc finger protein 534
chr5_+_154237778 0.156 ENST00000523698.1
ENST00000517876.1
ENST00000520472.1
CNOT8


CCR4-NOT transcription complex, subunit 8


chr12_+_25348139 0.151 ENST00000557540.2
ENST00000381356.4
LYRM5

LYR motif containing 5

chr6_+_26199737 0.151 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr1_-_72566613 0.150 ENST00000306821.3
NEGR1
neuronal growth regulator 1
chr8_-_10512569 0.147 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr7_-_77325545 0.145 ENST00000447009.1
ENST00000416650.1
ENST00000440088.1
ENST00000430801.1
ENST00000398043.2
RSBN1L-AS1




RSBN1L antisense RNA 1




chr2_+_86333340 0.144 ENST00000409783.2
ENST00000409277.3
PTCD3

pentatricopeptide repeat domain 3

chr18_+_20714525 0.144 ENST00000400473.2
CABLES1
Cdk5 and Abl enzyme substrate 1
chr10_+_180643 0.143 ENST00000509513.2
ENST00000397959.3
ZMYND11

zinc finger, MYND-type containing 11

chr12_-_56727676 0.142 ENST00000547572.1
ENST00000257931.5
ENST00000440411.3
PAN2


PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)


chrX_-_138724677 0.141 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF2


MCF.2 cell line derived transforming sequence


chr22_+_41956767 0.141 ENST00000306149.7
CSDC2
cold shock domain containing C2, RNA binding
chr3_+_118892362 0.140 ENST00000497685.1
ENST00000264234.3
UPK1B

uroplakin 1B

chr8_-_18744528 0.139 ENST00000523619.1
PSD3
pleckstrin and Sec7 domain containing 3
chr1_+_44514040 0.139 ENST00000431800.1
ENST00000437643.1
RP5-1198O20.4

RP5-1198O20.4

chr1_+_53480598 0.138 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
SCP2





sterol carrier protein 2





chr15_-_42749711 0.138 ENST00000565611.1
ENST00000263805.4
ENST00000565948.1
ZNF106


zinc finger protein 106


chrX_-_115085422 0.137 ENST00000430756.2
RP11-761E20.1
RP11-761E20.1
chr12_+_25348186 0.137 ENST00000555711.1
ENST00000556885.1
ENST00000554266.1
ENST00000556351.1
ENST00000556927.1
ENST00000556402.1
ENST00000553788.1
LYRM5






LYR motif containing 5






chr11_-_96076334 0.134 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr1_-_224624730 0.134 ENST00000445239.1
WDR26
WD repeat domain 26
chr6_+_52285046 0.133 ENST00000371068.5
EFHC1
EF-hand domain (C-terminal) containing 1
chr5_+_154238096 0.132 ENST00000517568.1
ENST00000524105.1
ENST00000285896.6
CNOT8


CCR4-NOT transcription complex, subunit 8


chr17_-_74733404 0.132 ENST00000508921.3
ENST00000583836.1
ENST00000358156.6
ENST00000392485.2
ENST00000359995.5
SRSF2




serine/arginine-rich splicing factor 2




chr6_-_26199499 0.132 ENST00000377831.5
HIST1H3D
histone cluster 1, H3d
chr2_+_54342574 0.131 ENST00000303536.4
ENST00000394666.3
ACYP2

acylphosphatase 2, muscle type

chr11_-_115158193 0.130 ENST00000543540.1
CADM1
cell adhesion molecule 1
chrX_-_55187588 0.130 ENST00000472571.2
ENST00000332132.4
ENST00000425133.2
ENST00000358460.4
FAM104B



family with sequence similarity 104, member B



chr5_+_154238149 0.130 ENST00000519430.1
ENST00000520671.1
ENST00000521583.1
ENST00000518028.1
ENST00000519404.1
ENST00000519394.1
ENST00000518775.1
CNOT8






CCR4-NOT transcription complex, subunit 8






chr12_+_72061563 0.129 ENST00000551238.1
THAP2
THAP domain containing, apoptosis associated protein 2
chr21_+_35107346 0.129 ENST00000456489.1
ITSN1
intersectin 1 (SH3 domain protein)
chr1_-_13452656 0.128 ENST00000376132.3
PRAMEF13
PRAME family member 13
chr5_+_154238042 0.128 ENST00000519211.1
ENST00000522458.1
ENST00000519903.1
ENST00000521450.1
ENST00000403027.2
CNOT8




CCR4-NOT transcription complex, subunit 8




chr17_-_5321549 0.127 ENST00000572809.1
NUP88
nucleoporin 88kDa
chr14_-_75536182 0.127 ENST00000555463.1
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr1_+_104159999 0.126 ENST00000414303.2
ENST00000423678.1
AMY2A

amylase, alpha 2A (pancreatic)

chr2_-_14541060 0.125 ENST00000418420.1
ENST00000417751.1
LINC00276

long intergenic non-protein coding RNA 276

chr16_-_15149917 0.124 ENST00000287706.3
NTAN1
N-terminal asparagine amidase
chr3_+_190333097 0.124 ENST00000412080.1
IL1RAP
interleukin 1 receptor accessory protein
chr7_+_132937820 0.123 ENST00000393161.2
ENST00000253861.4
EXOC4

exocyst complex component 4

chr13_-_31191642 0.120 ENST00000405805.1
HMGB1
high mobility group box 1
chr16_+_77756399 0.119 ENST00000564085.1
ENST00000268533.5
ENST00000568787.1
ENST00000437314.3
ENST00000563839.1
NUDT7




nudix (nucleoside diphosphate linked moiety X)-type motif 7




chr14_-_31926701 0.119 ENST00000310850.4
DTD2
D-tyrosyl-tRNA deacylase 2 (putative)
chr2_-_74570520 0.118 ENST00000394019.2
ENST00000346834.4
ENST00000359484.4
ENST00000423644.1
ENST00000377634.4
ENST00000436454.1
SLC4A5





solute carrier family 4 (sodium bicarbonate cotransporter), member 5





chr5_+_172571445 0.118 ENST00000231668.9
ENST00000351486.5
ENST00000352523.6
ENST00000393770.4
BNIP1



BCL2/adenovirus E1B 19kDa interacting protein 1



chr5_+_102201687 0.115 ENST00000304400.7
PAM
peptidylglycine alpha-amidating monooxygenase
chr1_-_220219775 0.115 ENST00000609181.1
EPRS
glutamyl-prolyl-tRNA synthetase
chr14_-_31926595 0.114 ENST00000547378.1
RP11-176H8.1
Uncharacterized protein
chrX_+_133733457 0.113 ENST00000440614.1
RP11-308B5.2
RP11-308B5.2
chr4_+_166794383 0.111 ENST00000061240.2
ENST00000507499.1
TLL1

tolloid-like 1

chr9_-_13279563 0.111 ENST00000541718.1
MPDZ
multiple PDZ domain protein
chr5_-_95297678 0.108 ENST00000237853.4
ELL2
elongation factor, RNA polymerase II, 2
chr1_+_180601139 0.107 ENST00000367590.4
ENST00000367589.3
XPR1

xenotropic and polytropic retrovirus receptor 1

chr6_+_73076432 0.107 ENST00000414192.2
RIMS1
regulating synaptic membrane exocytosis 1
chr2_-_114461655 0.107 ENST00000424612.1
AC017074.2
AC017074.2
chr1_+_219347203 0.106 ENST00000366927.3
LYPLAL1
lysophospholipase-like 1
chr1_-_220220000 0.106 ENST00000366923.3
EPRS
glutamyl-prolyl-tRNA synthetase
chrX_-_74376108 0.106 ENST00000339447.4
ENST00000373394.3
ENST00000529949.1
ENST00000534524.1
ENST00000253577.3
ABCB7




ATP-binding cassette, sub-family B (MDR/TAP), member 7




chr5_+_68513557 0.106 ENST00000256441.4
MRPS36
mitochondrial ribosomal protein S36
chr4_-_142134031 0.106 ENST00000420921.2
RNF150
ring finger protein 150
chr17_-_7145475 0.104 ENST00000571129.1
ENST00000571253.1
ENST00000573928.1
GABARAP


GABA(A) receptor-associated protein


chr5_+_102201722 0.104 ENST00000274392.9
ENST00000455264.2
PAM

peptidylglycine alpha-amidating monooxygenase

chr1_-_21377383 0.103 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr2_+_201994208 0.103 ENST00000440180.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr13_+_20268547 0.103 ENST00000601204.1
AL354808.2
AL354808.2
chr12_-_75784669 0.102 ENST00000552497.1
ENST00000551829.1
ENST00000436898.1
ENST00000442339.2
CAPS2



calcyphosine 2



chr5_+_68513622 0.102 ENST00000512880.1
ENST00000602380.1
MRPS36

mitochondrial ribosomal protein S36

chr13_-_81801115 0.102 ENST00000567258.1
LINC00564
long intergenic non-protein coding RNA 564
chr16_+_31724552 0.100 ENST00000539915.1
ENST00000316491.9
ENST00000399681.3
ENST00000398696.3
ENST00000534369.1
ZNF720




zinc finger protein 720




chr12_-_111395610 0.100 ENST00000548329.1
ENST00000546852.1
RP1-46F2.3

RP1-46F2.3

chr2_+_196313239 0.098 ENST00000413290.1
AC064834.1
AC064834.1
chr10_+_70661014 0.098 ENST00000373585.3
DDX50
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr15_+_101256294 0.097 ENST00000559755.1
RP11-66B24.5
RP11-66B24.5
chr2_+_131328402 0.096 ENST00000409793.1
ENST00000409982.1
AC140481.2

Uncharacterized protein

chr2_+_86333301 0.096 ENST00000254630.7
PTCD3
pentatricopeptide repeat domain 3
chr12_+_12878829 0.096 ENST00000326765.6
APOLD1
apolipoprotein L domain containing 1
chr14_-_31926623 0.096 ENST00000356180.4
DTD2
D-tyrosyl-tRNA deacylase 2 (putative)
chr19_+_32836499 0.095 ENST00000311921.4
ENST00000544431.1
ENST00000355898.5
ZNF507


zinc finger protein 507


chr10_-_33281363 0.095 ENST00000534049.1
ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr5_-_95297534 0.095 ENST00000513343.1
ENST00000431061.2
ELL2

elongation factor, RNA polymerase II, 2

chrX_-_55187531 0.093 ENST00000489298.1
ENST00000477847.2
FAM104B

family with sequence similarity 104, member B

chr1_+_17575584 0.093 ENST00000375460.3
PADI3
peptidyl arginine deiminase, type III
chrX_-_84363974 0.092 ENST00000395409.3
ENST00000332921.5
ENST00000509231.1
SATL1


spermidine/spermine N1-acetyl transferase-like 1


chr12_-_118796971 0.092 ENST00000542902.1
TAOK3
TAO kinase 3
chr1_+_170501270 0.092 ENST00000367763.3
ENST00000367762.1
GORAB

golgin, RAB6-interacting

chr5_-_70316537 0.091 ENST00000508426.2
NAIP
NLR family, apoptosis inhibitory protein
chr17_-_73401567 0.090 ENST00000392562.1
GRB2
growth factor receptor-bound protein 2
chr11_-_85376121 0.089 ENST00000527447.1
CREBZF
CREB/ATF bZIP transcription factor
chr6_-_75960024 0.089 ENST00000370081.2
COX7A2
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
chr4_+_169552748 0.088 ENST00000504519.1
ENST00000512127.1
PALLD

palladin, cytoskeletal associated protein

chr14_-_30766223 0.088 ENST00000549360.1
ENST00000508469.2
CTD-2251F13.1

CTD-2251F13.1

chr15_-_49912987 0.087 ENST00000560246.1
ENST00000558594.1
FAM227B

family with sequence similarity 227, member B

chr13_+_20207782 0.087 ENST00000414242.2
ENST00000361479.5
MPHOSPH8

M-phase phosphoprotein 8

chr1_-_42801540 0.087 ENST00000372573.1
FOXJ3
forkhead box J3
chr15_+_40544749 0.086 ENST00000559617.1
ENST00000560684.1
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr7_+_30589829 0.085 ENST00000579437.1
RP4-777O23.1
RP4-777O23.1
chr17_-_7145106 0.085 ENST00000577035.1
GABARAP
GABA(A) receptor-associated protein
chr3_-_149093499 0.083 ENST00000472441.1
TM4SF1
transmembrane 4 L six family member 1
chr2_-_175629135 0.083 ENST00000409542.1
ENST00000409219.1
CHRNA1

cholinergic receptor, nicotinic, alpha 1 (muscle)

chr4_-_14889791 0.083 ENST00000509654.1
ENST00000515031.1
ENST00000505089.2
LINC00504


long intergenic non-protein coding RNA 504


chr3_+_179280668 0.083 ENST00000429709.2
ENST00000450518.2
ENST00000392662.1
ENST00000490364.1
ACTL6A



actin-like 6A



chr15_-_49912944 0.082 ENST00000559905.1
FAM227B
family with sequence similarity 227, member B
chr12_-_56727487 0.081 ENST00000548043.1
ENST00000425394.2
PAN2

PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

chr3_+_135969148 0.081 ENST00000251654.4
ENST00000490504.1
ENST00000483687.1
ENST00000468777.1
ENST00000462637.1
ENST00000466072.1
ENST00000482086.1
ENST00000471595.1
ENST00000469217.1
ENST00000465423.1
ENST00000478469.1
PCCB










propionyl CoA carboxylase, beta polypeptide










chr16_-_70323422 0.081 ENST00000261772.8
AARS
alanyl-tRNA synthetase
chr21_+_47013566 0.080 ENST00000441095.1
ENST00000424569.1
AL133493.2

AL133493.2

chrX_-_122756660 0.080 ENST00000441692.1
THOC2
THO complex 2
chr18_+_39766626 0.079 ENST00000593234.1
ENST00000585627.1
ENST00000591199.1
ENST00000586990.1
ENST00000593051.1
ENST00000593316.1
ENST00000591381.1
ENST00000585639.1
ENST00000589068.1
LINC00907








long intergenic non-protein coding RNA 907








chr1_+_78383813 0.078 ENST00000342754.5
NEXN
nexilin (F actin binding protein)
chr2_+_101437487 0.077 ENST00000427413.1
ENST00000542504.1
NPAS2

neuronal PAS domain protein 2

chr8_-_62602327 0.077 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH









aspartate beta-hydroxylase









chr20_-_17539456 0.077 ENST00000544874.1
ENST00000377868.2
BFSP1

beaded filament structural protein 1, filensin

chr6_-_134639180 0.077 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr19_-_3061397 0.075 ENST00000586839.1
AES
amino-terminal enhancer of split
chr1_+_95616933 0.075 ENST00000604203.1
RP11-57H12.6
TMEM56-RWDD3 readthrough
chr4_-_89951028 0.075 ENST00000506913.1
FAM13A
family with sequence similarity 13, member A
chr17_-_57158523 0.075 ENST00000581468.1
TRIM37
tripartite motif containing 37
chr5_-_150537279 0.075 ENST00000517486.1
ENST00000377751.5
ENST00000356496.5
ENST00000521512.1
ENST00000517757.1
ENST00000354546.5
ANXA6





annexin A6





chr12_+_120740119 0.074 ENST00000536460.1
ENST00000202967.4
SIRT4

sirtuin 4

chr11_-_5526834 0.073 ENST00000380252.1
ENST00000380237.1
ENST00000396895.1
HBG2
HBE1

hemoglobin, gamma G
hemoglobin, epsilon 1

chr14_-_102552659 0.073 ENST00000441629.2
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr22_+_45725524 0.073 ENST00000405548.3
FAM118A
family with sequence similarity 118, member A
chr5_-_140700322 0.073 ENST00000313368.5
TAF7
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
chr1_-_13673511 0.073 ENST00000344998.3
ENST00000334600.6
PRAMEF14

PRAME family member 14

chr10_+_18689637 0.073 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr14_+_21566980 0.072 ENST00000418511.2
ENST00000554329.2
TMEM253

transmembrane protein 253

chr10_+_90424196 0.072 ENST00000394375.3
ENST00000608620.1
ENST00000238983.4
ENST00000355843.2
LIPF



lipase, gastric



chr2_-_10587897 0.072 ENST00000405333.1
ENST00000443218.1
ODC1

ornithine decarboxylase 1

chr5_-_70316737 0.071 ENST00000194097.4
NAIP
NLR family, apoptosis inhibitory protein
chr15_-_38519066 0.071 ENST00000561320.1
ENST00000561161.1
RP11-346D14.1

RP11-346D14.1

chr17_+_57408994 0.071 ENST00000312655.4
YPEL2
yippee-like 2 (Drosophila)
chr4_+_22999152 0.071 ENST00000511453.1
RP11-412P11.1
RP11-412P11.1
chr16_-_21875424 0.071 ENST00000541674.1
NPIPB4
nuclear pore complex interacting protein family, member B4
chr4_+_77941685 0.070 ENST00000506731.1
SEPT11
septin 11
chr11_-_95522907 0.070 ENST00000358780.5
ENST00000542135.1
FAM76B

family with sequence similarity 76, member B

chr11_+_118230287 0.069 ENST00000252108.3
ENST00000431736.2
UBE4A

ubiquitination factor E4A

chr6_+_135502466 0.069 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr5_-_180665195 0.069 ENST00000509148.1
GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr20_-_33999766 0.068 ENST00000349714.5
ENST00000438533.1
ENST00000359226.2
ENST00000374384.2
ENST00000374377.5
ENST00000407996.2
ENST00000424405.1
ENST00000542501.1
ENST00000397554.1
ENST00000540457.1
ENST00000374380.2
ENST00000374385.5
UQCC1











ubiquinol-cytochrome c reductase complex assembly factor 1











chr2_-_161350305 0.068 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr11_-_95522639 0.068 ENST00000536839.1
FAM76B
family with sequence similarity 76, member B
chr6_-_134639042 0.068 ENST00000461976.2
SGK1
serum/glucocorticoid regulated kinase 1
chr3_-_120461378 0.067 ENST00000273375.3
RABL3
RAB, member of RAS oncogene family-like 3
chr11_+_4116054 0.067 ENST00000423050.2
RRM1
ribonucleotide reductase M1
chr3_-_93781750 0.066 ENST00000314636.2
DHFRL1
dihydrofolate reductase-like 1
chr15_+_71228826 0.066 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
LRRC49




leucine rich repeat containing 49




chr6_+_89791507 0.066 ENST00000354922.3
PNRC1
proline-rich nuclear receptor coactivator 1
chrX_+_77166172 0.066 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A


ATPase, Cu++ transporting, alpha polypeptide


chr15_+_44719790 0.065 ENST00000558791.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chrX_-_72347916 0.065 ENST00000373518.1
NAP1L6
nucleosome assembly protein 1-like 6
chr20_-_44298878 0.065 ENST00000324384.3
ENST00000356562.2
WFDC11

WAP four-disulfide core domain 11

chr2_+_228678550 0.065 ENST00000409189.3
ENST00000358813.4
CCL20

chemokine (C-C motif) ligand 20

chr12_-_15815626 0.065 ENST00000540613.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr17_-_59668550 0.065 ENST00000521764.1
NACA2
nascent polypeptide-associated complex alpha subunit 2
chr15_-_34880646 0.065 ENST00000543376.1
GOLGA8A
golgin A8 family, member A
chr5_-_1882858 0.063 ENST00000511126.1
ENST00000231357.2
IRX4

iroquois homeobox 4

chr8_-_86575726 0.063 ENST00000379010.2
REXO1L1
REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1, pseudogene
chr17_+_79031415 0.062 ENST00000572073.1
ENST00000573677.1
BAIAP2

BAI1-associated protein 2

chr2_-_55237484 0.062 ENST00000394609.2
RTN4
reticulon 4
chr6_+_130339710 0.062 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3


l(3)mbt-like 3 (Drosophila)


chr16_+_6533729 0.061 ENST00000551752.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr7_+_134331550 0.060 ENST00000344924.3
ENST00000418040.1
ENST00000393132.2
BPGM


2,3-bisphosphoglycerate mutase


chr3_+_157827841 0.060 ENST00000295930.3
ENST00000471994.1
ENST00000464171.1
ENST00000312179.6
ENST00000475278.2
RSRC1




arginine/serine-rich coiled-coil 1





Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.2 0.5 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.2 1.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890) chylomicron remodeling(GO:0034371)
0.1 0.2 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.1 0.2 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
0.0 0.0 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.0 0.2 GO:0007210 serotonin receptor signaling pathway(GO:0007210) positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.2 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0 0.2 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.2 GO:0015692 lead ion transport(GO:0015692)
0.0 0.3 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.0 0.4 GO:0060453 regulation of gastric acid secretion(GO:0060453)
0.0 0.1 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.1 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.1 GO:0071284 cellular response to lead ion(GO:0071284)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.2 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0021943 regulation of collagen catabolic process(GO:0010710) formation of radial glial scaffolds(GO:0021943)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.2 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.0 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.8 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.1 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0 0.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.0 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.1 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.0 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 0.4 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.0 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0042627 chylomicron(GO:0042627)
0.1 0.2 GO:0031251 PAN complex(GO:0031251)
0.1 0.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0017129 triglyceride binding(GO:0017129)
0.1 0.5 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.2 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.1 0.2 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.2 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.1 GO:0019808 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.0 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.4 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.1 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.6 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0032767 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.0 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.0 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.0 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.2 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 0.2 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.0 0.5 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA