Motif ID: DMBX1

Z-value: 0.292


Transcription factors associated with DMBX1:

Gene SymbolEntrez IDGene Name
DMBX1 ENSG00000197587.6 DMBX1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
DMBX1hg19_v2_chr1_+_46972668_46972669-0.393.0e-01Click!


Activity profile for motif DMBX1.

activity profile for motif DMBX1


Sorted Z-values histogram for motif DMBX1

Sorted Z-values for motif DMBX1



Network of associatons between targets according to the STRING database.



First level regulatory network of DMBX1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_103986085 0.355 ENST00000370005.3
 ELOVL3
ELOVL fatty acid elongase 3
chr11_+_58938903 0.162 ENST00000532982.1
 DTX4
deltex homolog 4 (Drosophila)
chr16_-_31076332 0.161 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
 ZNF668


zinc finger protein 668


chr1_-_165414414 0.159 ENST00000359842.5
 RXRG
retinoid X receptor, gamma
chr5_-_54988448 0.136 ENST00000503817.1
ENST00000512595.1
 SLC38A9

solute carrier family 38, member 9

chr19_+_41284121 0.126 ENST00000594800.1
ENST00000357052.2
ENST00000602173.1
 RAB4B


RAB4B, member RAS oncogene family


chr16_-_31076273 0.125 ENST00000426488.2
 ZNF668
zinc finger protein 668
chr11_-_45940343 0.114 ENST00000532681.1
 PEX16
peroxisomal biogenesis factor 16
chr2_+_223725723 0.093 ENST00000535678.1
 ACSL3
acyl-CoA synthetase long-chain family member 3
chr3_+_99986036 0.092 ENST00000471098.1
 TBC1D23
TBC1 domain family, member 23
chr3_+_49057876 0.085 ENST00000326912.4
 NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr8_-_23282797 0.079 ENST00000524144.1
 LOXL2
lysyl oxidase-like 2
chr6_-_33297013 0.078 ENST00000453407.1
 DAXX
death-domain associated protein
chr5_-_54988559 0.078 ENST00000502247.1
 SLC38A9
solute carrier family 38, member 9
chr8_-_23282820 0.074 ENST00000520871.1
 LOXL2
lysyl oxidase-like 2
chr2_+_223725652 0.071 ENST00000357430.3
ENST00000392066.3
 ACSL3

acyl-CoA synthetase long-chain family member 3

chr1_-_47655686 0.069 ENST00000294338.2
 PDZK1IP1
PDZK1 interacting protein 1
chr3_+_49058444 0.066 ENST00000326925.6
ENST00000395458.2
 NDUFAF3

NADH dehydrogenase (ubiquinone) complex I, assembly factor 3

chr17_+_16945820 0.066 ENST00000577514.1
 MPRIP
myosin phosphatase Rho interacting protein
chr11_+_61248583 0.065 ENST00000432063.2
ENST00000338608.2
 PPP1R32

protein phosphatase 1, regulatory subunit 32

chr1_-_16563641 0.056 ENST00000375599.3
 RSG1
REM2 and RAB-like small GTPase 1
chr3_-_10362725 0.053 ENST00000397109.3
ENST00000428626.1
ENST00000445064.1
ENST00000431352.1
ENST00000397117.1
ENST00000337354.4
ENST00000383801.2
ENST00000432213.1
ENST00000350697.3
 SEC13








SEC13 homolog (S. cerevisiae)








chr9_-_21995249 0.053 ENST00000494262.1
 CDKN2A
cyclin-dependent kinase inhibitor 2A
chr15_-_61521495 0.052 ENST00000335670.6
 RORA
RAR-related orphan receptor A
chr9_-_21995300 0.047 ENST00000498628.2
 CDKN2A
cyclin-dependent kinase inhibitor 2A
chr3_+_111393501 0.043 ENST00000393934.3
 PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr5_+_50678921 0.040 ENST00000230658.7
 ISL1
ISL LIM homeobox 1
chr2_-_70780770 0.039 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
 TGFA


transforming growth factor, alpha


chr5_+_50679506 0.038 ENST00000511384.1
 ISL1
ISL LIM homeobox 1
chr6_-_26250835 0.037 ENST00000446824.2
 HIST1H3F
histone cluster 1, H3f
chr1_-_94586651 0.036 ENST00000535735.1
ENST00000370225.3
 ABCA4

ATP-binding cassette, sub-family A (ABC1), member 4

chr19_-_17186229 0.034 ENST00000253669.5
ENST00000448593.2
 HAUS8

HAUS augmin-like complex, subunit 8

chr8_+_86999516 0.032 ENST00000521564.1
 ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr10_+_74451883 0.031 ENST00000373053.3
ENST00000357157.6
 MCU

mitochondrial calcium uniporter

chr12_-_10959892 0.030 ENST00000240615.2
 TAS2R8
taste receptor, type 2, member 8
chrX_-_48931648 0.030 ENST00000376386.3
ENST00000376390.4
 PRAF2

PRA1 domain family, member 2

chr11_-_36619771 0.029 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
 RAG2


recombination activating gene 2


chr6_-_138893661 0.028 ENST00000427025.2
 NHSL1
NHS-like 1
chr7_+_1727755 0.027 ENST00000424383.2
 ELFN1
extracellular leucine-rich repeat and fibronectin type III domain containing 1
chr12_-_56321649 0.025 ENST00000454792.2
ENST00000408946.2
 WIBG

within bgcn homolog (Drosophila)

chr19_+_17448348 0.025 ENST00000324894.8
ENST00000358792.7
ENST00000600625.1
 GTPBP3


GTP binding protein 3 (mitochondrial)


chr9_-_21994344 0.024 ENST00000530628.2
ENST00000361570.3
 CDKN2A

cyclin-dependent kinase inhibitor 2A

chr20_+_34556488 0.024 ENST00000373973.3
ENST00000349339.1
ENST00000538900.1
 CNBD2


cyclic nucleotide binding domain containing 2


chr2_-_175711133 0.023 ENST00000409597.1
ENST00000413882.1
 CHN1

chimerin 1

chr8_-_125577940 0.023 ENST00000519168.1
ENST00000395508.2
 MTSS1

metastasis suppressor 1

chr19_-_17185848 0.022 ENST00000593360.1
 HAUS8
HAUS augmin-like complex, subunit 8
chr17_-_38859996 0.020 ENST00000264651.2
 KRT24
keratin 24
chr2_-_220252068 0.020 ENST00000430206.1
ENST00000429013.1
 DNPEP

aspartyl aminopeptidase

chr17_-_48207157 0.020 ENST00000330175.4
ENST00000503131.1
 SAMD14

sterile alpha motif domain containing 14

chr14_+_50234309 0.020 ENST00000298307.5
 KLHDC2
kelch domain containing 2
chr12_-_21487829 0.019 ENST00000445053.1
ENST00000452078.1
ENST00000458504.1
ENST00000422327.1
ENST00000421294.1
 SLCO1A2




solute carrier organic anion transporter family, member 1A2




chr2_+_97454321 0.019 ENST00000540067.1
 CNNM4
cyclin M4
chr17_-_19651654 0.018 ENST00000395555.3
 ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr9_-_21994597 0.018 ENST00000579755.1
 CDKN2A
cyclin-dependent kinase inhibitor 2A
chr7_-_48068671 0.018 ENST00000297325.4
 SUN3
Sad1 and UNC84 domain containing 3
chr3_-_137851220 0.017 ENST00000236709.3
 A4GNT
alpha-1,4-N-acetylglucosaminyltransferase
chr17_-_19651668 0.017 ENST00000494157.2
ENST00000225740.6
 ALDH3A1

aldehyde dehydrogenase 3 family, member A1

chr1_+_180875711 0.016 ENST00000434447.1
 RP11-46A10.2
RP11-46A10.2
chr9_+_74920335 0.015 ENST00000451596.2
ENST00000436054.1
 RP11-63P12.6

RP11-63P12.6

chr3_-_16524357 0.014 ENST00000432519.1
 RFTN1
raftlin, lipid raft linker 1
chr14_-_23395623 0.014 ENST00000556043.1
 PRMT5
protein arginine methyltransferase 5
chr15_+_93443419 0.013 ENST00000557381.1
ENST00000420239.2
 CHD2

chromodomain helicase DNA binding protein 2

chr3_+_136649311 0.013 ENST00000469404.1
ENST00000467911.1
 NCK1

NCK adaptor protein 1

chr7_+_143747461 0.012 ENST00000408906.2
 OR2A5
olfactory receptor, family 2, subfamily A, member 5
chr17_-_12921270 0.012 ENST00000578071.1
ENST00000426905.3
ENST00000395962.2
ENST00000583371.1
ENST00000338034.4
 ELAC2




elaC ribonuclease Z 2




chr15_+_53408561 0.012 ENST00000559915.1
 RP11-209E8.1
RP11-209E8.1
chr12_-_118628315 0.011 ENST00000540561.1
 TAOK3
TAO kinase 3
chr7_-_48068643 0.011 ENST00000453192.2
 SUN3
Sad1 and UNC84 domain containing 3
chr12_+_53693812 0.011 ENST00000549488.1
 C12orf10
chromosome 12 open reading frame 10
chr3_+_111393659 0.011 ENST00000477665.1
 PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chrX_-_32173579 0.010 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
 DMD




dystrophin




chr4_+_41937131 0.010 ENST00000504986.1
ENST00000508448.1
ENST00000513702.1
ENST00000325094.5
 TMEM33



transmembrane protein 33



chr17_+_68100989 0.010 ENST00000585558.1
ENST00000392670.1
 KCNJ16

potassium inwardly-rectifying channel, subfamily J, member 16

chr21_-_35016231 0.009 ENST00000438788.1
 CRYZL1
crystallin, zeta (quinone reductase)-like 1
chr4_-_170679024 0.009 ENST00000393381.2
 C4orf27
chromosome 4 open reading frame 27
chr12_-_49581152 0.008 ENST00000550811.1
 TUBA1A
tubulin, alpha 1a
chr9_+_74920408 0.008 ENST00000451152.1
 RP11-63P12.6
RP11-63P12.6
chr19_-_6459746 0.007 ENST00000301454.4
ENST00000334510.5
 SLC25A23

solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23

chr4_+_108815402 0.007 ENST00000503385.1
 SGMS2
sphingomyelin synthase 2
chr7_-_142181009 0.006 ENST00000390368.2
 TRBV6-5
T cell receptor beta variable 6-5
chr17_-_19651598 0.006 ENST00000570414.1
 ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr2_-_165811756 0.005 ENST00000409662.1
 SLC38A11
solute carrier family 38, member 11
chr19_+_36157715 0.004 ENST00000379013.2
ENST00000222275.2
 UPK1A

uroplakin 1A

chr3_-_49058479 0.004 ENST00000440857.1
 DALRD3
DALR anticodon binding domain containing 3
chr18_-_35145593 0.004 ENST00000334919.5
ENST00000591282.1
ENST00000588597.1
 CELF4


CUGBP, Elav-like family member 4


chr16_-_54304608 0.003 ENST00000561336.1
 RP11-324D17.1
HCG2045435; Uncharacterized protein
chr5_+_71403280 0.003 ENST00000511641.2
 MAP1B
microtubule-associated protein 1B
chr10_-_35104185 0.002 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
 PARD3










par-3 family cell polarity regulator










chr2_-_70780572 0.002 ENST00000450929.1
 TGFA
transforming growth factor, alpha
chr1_+_162351503 0.001 ENST00000458626.2
 C1orf226
chromosome 1 open reading frame 226
chr3_-_179692042 0.001 ENST00000468741.1
 PEX5L
peroxisomal biogenesis factor 5-like
chr18_-_35145689 0.001 ENST00000591287.1
ENST00000601019.1
ENST00000601392.1
 CELF4


CUGBP, Elav-like family member 4


chr12_-_56321397 0.001 ENST00000557259.1
ENST00000549939.1
 WIBG

within bgcn homolog (Drosophila)

chr6_+_89791507 0.001 ENST00000354922.3
 PNRC1
proline-rich nuclear receptor coactivator 1
chr1_+_109756523 0.000 ENST00000234677.2
ENST00000369923.4
 SARS

seryl-tRNA synthetase


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.0 0.2 GO:0018277 protein deamination(GO:0018277)
0.0 0.1 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0060913 cardiac cell fate determination(GO:0060913)
0.0 0.1 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.0 0.1 GO:2000111 senescence-associated heterochromatin focus assembly(GO:0035986) positive regulation of macrophage apoptotic process(GO:2000111)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.4 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs