Motif ID: DLX5

Z-value: 0.210


Transcription factors associated with DLX5:

Gene SymbolEntrez IDGene Name
DLX5 ENSG00000105880.4 DLX5



Activity profile for motif DLX5.

activity profile for motif DLX5


Sorted Z-values histogram for motif DLX5

Sorted Z-values for motif DLX5



Network of associatons between targets according to the STRING database.



First level regulatory network of DLX5

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_33709268 0.287 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
 SLC39A6


solute carrier family 39 (zinc transporter), member 6


chr2_-_183387430 0.265 ENST00000410103.1
 PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr2_-_183387064 0.261 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
 PDE1A



phosphodiesterase 1A, calmodulin-dependent



chr2_-_183387283 0.199 ENST00000435564.1
 PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr3_-_52567792 0.147 ENST00000307092.4
ENST00000422318.2
ENST00000459839.1
 NT5DC2


5'-nucleotidase domain containing 2


chr11_+_115498761 0.147 ENST00000424313.2
 AP000997.1
AP000997.1
chr2_+_30369807 0.138 ENST00000379520.3
ENST00000379519.3
ENST00000261353.4
 YPEL5


yippee-like 5 (Drosophila)


chr2_+_30369859 0.129 ENST00000402003.3
 YPEL5
yippee-like 5 (Drosophila)
chr8_-_124553437 0.128 ENST00000517956.1
ENST00000443022.2
 FBXO32

F-box protein 32

chrX_+_150565653 0.111 ENST00000330374.6
 VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr12_-_57039739 0.104 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
 ATP5B





ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide





chr17_-_37009882 0.100 ENST00000378096.3
ENST00000394332.1
ENST00000394333.1
ENST00000577407.1
ENST00000479035.2
 RPL23




ribosomal protein L23




chr6_-_27860956 0.092 ENST00000359611.2
 HIST1H2AM
histone cluster 1, H2am
chr7_+_97736197 0.086 ENST00000297293.5
 LMTK2
lemur tyrosine kinase 2
chrX_-_16887963 0.079 ENST00000380084.4
 RBBP7
retinoblastoma binding protein 7
chr3_-_180397256 0.075 ENST00000442201.2
 CCDC39
coiled-coil domain containing 39
chr4_-_89442940 0.069 ENST00000527353.1
 PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr5_-_58571935 0.068 ENST00000503258.1
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_-_44550441 0.061 ENST00000420756.1
ENST00000444696.1
 PREPL

prolyl endopeptidase-like

chr14_+_32798547 0.060 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
 AKAP6


A kinase (PRKA) anchor protein 6


chr7_-_86849883 0.059 ENST00000433078.1
 TMEM243
transmembrane protein 243, mitochondrial
chr9_+_34646651 0.059 ENST00000378842.3
 GALT
galactose-1-phosphate uridylyltransferase
chr1_-_23670817 0.059 ENST00000478691.1
 HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr1_+_61547894 0.054 ENST00000403491.3
 NFIA
nuclear factor I/A
chr7_+_99717230 0.053 ENST00000262932.3
 CNPY4
canopy FGF signaling regulator 4
chr1_-_28969517 0.051 ENST00000263974.4
ENST00000373824.4
 TAF12

TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa

chrX_+_100645812 0.051 ENST00000427805.2
ENST00000553110.3
ENST00000392994.3
ENST00000409338.1
ENST00000409170.3
 RPL36A


RPL36A-HNRNPH2

ribosomal protein L36a


RPL36A-HNRNPH2 readthrough

chr1_-_23670813 0.049 ENST00000374612.1
 HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr6_+_27861190 0.049 ENST00000303806.4
 HIST1H2BO
histone cluster 1, H2bo
chr9_+_34646624 0.045 ENST00000450095.2
ENST00000556278.1
 GALT
GALT
galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr9_+_116225999 0.044 ENST00000317613.6
 RGS3
regulator of G-protein signaling 3
chr17_+_28268623 0.043 ENST00000394835.3
ENST00000320856.5
ENST00000394832.2
ENST00000378738.3
 EFCAB5



EF-hand calcium binding domain 5



chr1_-_23670752 0.043 ENST00000302271.6
ENST00000426846.2
ENST00000427764.2
ENST00000606561.1
ENST00000374616.3
 HNRNPR




heterogeneous nuclear ribonucleoprotein R




chr3_-_105587879 0.042 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
 CBLB


Cbl proto-oncogene B, E3 ubiquitin protein ligase


chr5_+_173930676 0.042 ENST00000504512.1
 RP11-267A15.1
RP11-267A15.1
chr12_-_50616382 0.040 ENST00000552783.1
 LIMA1
LIM domain and actin binding 1
chr8_-_10512569 0.040 ENST00000382483.3
 RP1L1
retinitis pigmentosa 1-like 1
chr1_-_197115818 0.035 ENST00000367409.4
ENST00000294732.7
 ASPM

asp (abnormal spindle) homolog, microcephaly associated (Drosophila)

chr16_+_58010339 0.032 ENST00000290871.5
ENST00000441824.2
 TEPP

testis, prostate and placenta expressed

chr3_+_158519654 0.031 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
 MFSD1


major facilitator superfamily domain containing 1


chr6_-_33160231 0.029 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
 COL11A2









collagen, type XI, alpha 2









chr7_-_99716914 0.029 ENST00000431404.2
 TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr11_+_73498973 0.029 ENST00000537007.1
 MRPL48
mitochondrial ribosomal protein L48
chr6_-_112194484 0.029 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
 FYN






FYN oncogene related to SRC, FGR, YES






chr14_+_96000930 0.028 ENST00000331334.4
 GLRX5
glutaredoxin 5
chr11_+_76092353 0.027 ENST00000530460.1
ENST00000321844.4
 RP11-111M22.2

Homo sapiens putative uncharacterized protein FLJ37770-like (LOC100506127), mRNA.

chr6_-_38670897 0.027 ENST00000373365.4
 GLO1
glyoxalase I
chr2_+_196313239 0.026 ENST00000413290.1
 AC064834.1
AC064834.1
chr2_+_95963052 0.025 ENST00000295225.5
 KCNIP3
Kv channel interacting protein 3, calsenilin
chr1_-_151762900 0.025 ENST00000440583.2
 TDRKH
tudor and KH domain containing
chr3_+_186560476 0.023 ENST00000320741.2
ENST00000444204.2
 ADIPOQ

adiponectin, C1Q and collagen domain containing

chrX_+_100224676 0.021 ENST00000450049.2
 ARL13A
ADP-ribosylation factor-like 13A
chr12_-_53171128 0.019 ENST00000332411.2
 KRT76
keratin 76
chr13_-_36788718 0.018 ENST00000317764.6
ENST00000379881.3
 SOHLH2

spermatogenesis and oogenesis specific basic helix-loop-helix 2

chr4_-_7069760 0.017 ENST00000264954.4
 GRPEL1
GrpE-like 1, mitochondrial (E. coli)
chr11_+_73498898 0.017 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
 MRPL48





mitochondrial ribosomal protein L48





chr3_+_186560462 0.017 ENST00000412955.2
 ADIPOQ
adiponectin, C1Q and collagen domain containing
chr13_+_111748183 0.014 ENST00000422994.1
 LINC00368
long intergenic non-protein coding RNA 368
chr12_+_7014126 0.014 ENST00000415834.1
ENST00000436789.1
 LRRC23

leucine rich repeat containing 23

chr22_-_30960876 0.014 ENST00000401975.1
ENST00000428682.1
ENST00000423299.1
 GAL3ST1


galactose-3-O-sulfotransferase 1


chr19_+_58570605 0.014 ENST00000359978.6
ENST00000401053.4
ENST00000439855.2
ENST00000313434.5
ENST00000511556.1
ENST00000506786.1
 ZNF135





zinc finger protein 135





chr11_-_71823715 0.013 ENST00000545944.1
ENST00000502597.2
 ANAPC15

anaphase promoting complex subunit 15

chr19_-_14785698 0.013 ENST00000344373.4
ENST00000595472.1
 EMR3

egf-like module containing, mucin-like, hormone receptor-like 3

chr10_-_99205607 0.013 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
 EXOSC1





exosome component 1





chr1_+_202317815 0.012 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
 PPP1R12B


protein phosphatase 1, regulatory subunit 12B


chr8_+_32579271 0.011 ENST00000518084.1
 NRG1
neuregulin 1
chr22_-_32860427 0.011 ENST00000534972.1
ENST00000397450.1
ENST00000397452.1
 BPIFC


BPI fold containing family C


chr4_+_169575875 0.009 ENST00000503457.1
 PALLD
palladin, cytoskeletal associated protein
chr10_-_128110441 0.009 ENST00000456514.1
 LINC00601
long intergenic non-protein coding RNA 601
chr5_+_110559312 0.008 ENST00000508074.1
 CAMK4
calcium/calmodulin-dependent protein kinase IV
chr1_-_201140673 0.008 ENST00000367333.2
 TMEM9
transmembrane protein 9
chr12_+_54378923 0.008 ENST00000303460.4
 HOXC10
homeobox C10
chr12_+_7456880 0.008 ENST00000399422.4
 ACSM4
acyl-CoA synthetase medium-chain family member 4
chr11_+_118398178 0.008 ENST00000302783.4
ENST00000539546.1
 TTC36

tetratricopeptide repeat domain 36

chr2_+_105050794 0.008 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
 AC013402.2


long intergenic non-protein coding RNA 1102


chr5_+_173930710 0.008 ENST00000511707.1
 RP11-267A15.1
RP11-267A15.1
chr6_+_130339710 0.008 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
 L3MBTL3


l(3)mbt-like 3 (Drosophila)


chr1_+_54569968 0.007 ENST00000391366.1
 AL161915.1
Uncharacterized protein
chr15_+_96904487 0.007 ENST00000600790.1
 AC087477.1
Uncharacterized protein
chr12_+_64798826 0.006 ENST00000540203.1
 XPOT
exportin, tRNA
chr8_+_32579321 0.006 ENST00000522402.1
 NRG1
neuregulin 1
chr14_+_32798462 0.006 ENST00000280979.4
 AKAP6
A kinase (PRKA) anchor protein 6
chr11_-_102651343 0.005 ENST00000279441.4
ENST00000539681.1
 MMP10

matrix metallopeptidase 10 (stromelysin 2)

chr19_-_14785674 0.004 ENST00000253673.5
 EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr11_-_26743546 0.004 ENST00000280467.6
ENST00000396005.3
 SLC5A12

solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12

chr19_-_14785622 0.003 ENST00000443157.2
 EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr14_+_24540046 0.001 ENST00000397016.2
ENST00000537691.1
ENST00000560356.1
ENST00000558450.1
 CPNE6



copine VI (neuronal)



chr20_+_58571419 0.000 ENST00000244049.3
ENST00000350849.6
ENST00000456106.1
 CDH26


cadherin 26


chr12_+_52695617 0.000 ENST00000293525.5
 KRT86
keratin 86

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.0 0.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.0 GO:2000583 renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.0 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects