Motif ID: DLX4_HOXD8

Z-value: 0.804

Transcription factors associated with DLX4_HOXD8:

Gene SymbolEntrez IDGene Name
DLX4 ENSG00000108813.9 DLX4
HOXD8 ENSG00000175879.7 HOXD8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXD8hg19_v2_chr2_+_176994408_176994641-0.826.9e-03Click!
DLX4hg19_v2_chr17_+_48046538_48046575-0.827.4e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of DLX4_HOXD8

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_183538319 5.263 ENST00000420553.1
ENST00000419402.1
NCF2

neutrophil cytosolic factor 2

chr4_-_76957214 2.750 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr1_-_183559693 2.539 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
NCF2


neutrophil cytosolic factor 2


chr1_-_183560011 2.125 ENST00000367536.1
NCF2
neutrophil cytosolic factor 2
chr10_+_91152303 1.917 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr4_+_75174180 1.522 ENST00000413830.1
EPGN
epithelial mitogen
chr3_-_124653579 1.078 ENST00000478191.1
ENST00000311075.3
MUC13

mucin 13, cell surface associated

chr5_+_35852797 1.072 ENST00000508941.1
IL7R
interleukin 7 receptor
chr2_+_69201705 0.983 ENST00000377938.2
GKN1
gastrokine 1
chr4_+_75174204 0.898 ENST00000332112.4
ENST00000514968.1
ENST00000503098.1
ENST00000502358.1
ENST00000509145.1
ENST00000505212.1
EPGN





epithelial mitogen





chr1_+_79115503 0.888 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44


interferon-induced protein 44


chr4_-_169239921 0.851 ENST00000514995.1
ENST00000393743.3
DDX60

DEAD (Asp-Glu-Ala-Asp) box polypeptide 60

chr12_-_15114603 0.837 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chrX_-_1331527 0.816 ENST00000381567.3
ENST00000381566.1
ENST00000400841.2
CRLF2


cytokine receptor-like factor 2


chr9_+_130911723 0.769 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2


lipocalin 2


chr11_+_35201826 0.766 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr9_-_32526299 0.759 ENST00000379882.1
ENST00000379883.2
DDX58

DEAD (Asp-Glu-Ala-Asp) box polypeptide 58

chr22_-_36556821 0.757 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
APOL3


apolipoprotein L, 3


chr4_-_39033963 0.751 ENST00000381938.3
TMEM156
transmembrane protein 156
chr4_+_79472673 0.711 ENST00000264908.6
ANXA3
annexin A3
chr22_+_50981079 0.704 ENST00000609268.1
CTA-384D8.34
CTA-384D8.34
chr7_-_92777606 0.702 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L






sterile alpha motif domain containing 9-like






chr13_+_49551020 0.672 ENST00000541916.1
FNDC3A
fibronectin type III domain containing 3A
chr2_+_102413726 0.665 ENST00000350878.4
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr2_+_228736321 0.615 ENST00000309931.2
DAW1
dynein assembly factor with WDR repeat domains 1
chr9_+_130911770 0.590 ENST00000372998.1
LCN2
lipocalin 2
chr5_-_35938674 0.587 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
CAPSL



calcyphosine-like



chr12_-_15114658 0.585 ENST00000542276.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr8_+_38261880 0.571 ENST00000527175.1
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr18_+_52385068 0.552 ENST00000586570.1
RAB27B
RAB27B, member RAS oncogene family
chr11_-_59633951 0.552 ENST00000257264.3
TCN1
transcobalamin I (vitamin B12 binding protein, R binder family)
chr11_+_35222629 0.539 ENST00000526553.1
CD44
CD44 molecule (Indian blood group)
chr2_+_158114051 0.535 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr4_+_56815102 0.525 ENST00000257287.4
CEP135
centrosomal protein 135kDa
chr1_-_27998689 0.525 ENST00000339145.4
ENST00000362020.4
ENST00000361157.6
IFI6


interferon, alpha-inducible protein 6


chr16_-_71323617 0.491 ENST00000563876.1
CMTR2
cap methyltransferase 2
chr12_+_78359999 0.490 ENST00000550503.1
NAV3
neuron navigator 3
chr12_+_113344755 0.488 ENST00000550883.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr20_+_43803517 0.478 ENST00000243924.3
PI3
peptidase inhibitor 3, skin-derived
chr6_+_112668524 0.468 ENST00000441065.2
RFPL4B
ret finger protein-like 4B
chr12_+_113354341 0.460 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr10_-_28623368 0.451 ENST00000441595.2
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr3_-_151034734 0.448 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr12_-_70093111 0.444 ENST00000548658.1
ENST00000476098.1
ENST00000331471.4
ENST00000393365.1
BEST3



bestrophin 3



chr12_-_10321754 0.442 ENST00000539518.1
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr5_+_157158205 0.435 ENST00000231198.7
THG1L
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr15_+_59903975 0.429 ENST00000560585.1
ENST00000396065.1
GCNT3

glucosaminyl (N-acetyl) transferase 3, mucin type

chr5_+_89770664 0.416 ENST00000503973.1
ENST00000399107.1
POLR3G

polymerase (RNA) III (DNA directed) polypeptide G (32kD)

chr9_-_115095229 0.409 ENST00000210227.4
PTBP3
polypyrimidine tract binding protein 3
chr2_+_172309634 0.403 ENST00000339506.3
DCAF17
DDB1 and CUL4 associated factor 17
chr2_+_102456277 0.403 ENST00000421882.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr2_-_151395525 0.400 ENST00000439275.1
RND3
Rho family GTPase 3
chr7_-_149158187 0.400 ENST00000247930.4
ZNF777
zinc finger protein 777
chr17_-_29645836 0.394 ENST00000578584.1
CTD-2370N5.3
CTD-2370N5.3
chr4_+_110736659 0.392 ENST00000394631.3
ENST00000226796.6
GAR1

GAR1 ribonucleoprotein

chr1_-_205091115 0.384 ENST00000264515.6
ENST00000367164.1
RBBP5

retinoblastoma binding protein 5

chr5_-_94417186 0.383 ENST00000312216.8
ENST00000512425.1
MCTP1

multiple C2 domains, transmembrane 1

chr5_+_142286887 0.378 ENST00000451259.1
ARHGAP26
Rho GTPase activating protein 26
chr2_+_228736335 0.376 ENST00000440997.1
ENST00000545118.1
DAW1

dynein assembly factor with WDR repeat domains 1

chr10_+_90660832 0.372 ENST00000371924.1
STAMBPL1
STAM binding protein-like 1
chr16_-_30621663 0.371 ENST00000287461.3
ZNF689
zinc finger protein 689
chr14_+_52164820 0.368 ENST00000554167.1
FRMD6
FERM domain containing 6
chr12_-_92536433 0.367 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
C12orf79


chromosome 12 open reading frame 79


chr22_-_29107919 0.365 ENST00000434810.1
ENST00000456369.1
CHEK2

checkpoint kinase 2

chr16_-_66864806 0.364 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NAE1






NEDD8 activating enzyme E1 subunit 1






chr1_-_33430286 0.360 ENST00000373456.7
ENST00000356990.5
ENST00000235150.4
RNF19B


ring finger protein 19B


chr1_-_162381907 0.358 ENST00000367929.2
ENST00000359567.3
SH2D1B

SH2 domain containing 1B

chr2_+_201450591 0.357 ENST00000374700.2
AOX1
aldehyde oxidase 1
chr6_-_150346607 0.349 ENST00000367341.1
ENST00000286380.2
RAET1L

retinoic acid early transcript 1L

chr1_+_41448820 0.349 ENST00000372616.1
CTPS1
CTP synthase 1
chr16_+_81772633 0.344 ENST00000565054.1
ENST00000566191.1
ENST00000565272.1
ENST00000563954.1
PLCG2
RP11-960L18.1


phospholipase C, gamma 2 (phosphatidylinositol-specific)
RP11-960L18.1


chr12_-_123187890 0.342 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr12_-_123201337 0.342 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr7_-_139763521 0.337 ENST00000263549.3
PARP12
poly (ADP-ribose) polymerase family, member 12
chr19_-_39523165 0.334 ENST00000509137.2
ENST00000292853.4
FBXO27

F-box protein 27

chr1_+_64014588 0.333 ENST00000371086.2
ENST00000340052.3
DLEU2L

deleted in lymphocytic leukemia 2-like

chr2_+_102314161 0.330 ENST00000425019.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr2_-_225811747 0.329 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr14_-_100841670 0.326 ENST00000557297.1
ENST00000555813.1
ENST00000557135.1
ENST00000556698.1
ENST00000554509.1
ENST00000555410.1
WARS





tryptophanyl-tRNA synthetase





chr3_+_149191723 0.320 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr16_+_15489603 0.319 ENST00000287594.7
ENST00000568766.1
MPV17L
RP11-1021N1.1
MPV17 mitochondrial membrane protein-like
Uncharacterized protein
chr3_+_101504200 0.317 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr9_-_115095123 0.310 ENST00000458258.1
PTBP3
polypyrimidine tract binding protein 3
chr17_-_33760164 0.307 ENST00000445092.1
ENST00000394562.1
ENST00000447040.2
SLFN12


schlafen family member 12


chr3_+_158787041 0.305 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1


IQCJ-SCHIP1 readthrough


chr6_+_106988986 0.303 ENST00000457437.1
ENST00000535438.1
AIM1

absent in melanoma 1

chr12_-_10320190 0.302 ENST00000543993.1
ENST00000339968.6
OLR1

oxidized low density lipoprotein (lectin-like) receptor 1

chr8_+_27631903 0.302 ENST00000305188.8
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr5_+_147582348 0.302 ENST00000514389.1
SPINK6
serine peptidase inhibitor, Kazal type 6
chr4_+_123653807 0.299 ENST00000314218.3
ENST00000542236.1
BBS12

Bardet-Biedl syndrome 12

chr2_+_29320571 0.295 ENST00000401605.1
ENST00000401617.2
CLIP4

CAP-GLY domain containing linker protein family, member 4

chr12_-_15114492 0.292 ENST00000541546.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr8_-_101571933 0.290 ENST00000520311.1
ANKRD46
ankyrin repeat domain 46
chr5_+_179135246 0.287 ENST00000508787.1
CANX
calnexin
chr15_+_63188009 0.287 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr19_+_4247070 0.286 ENST00000262962.7
CCDC94
coiled-coil domain containing 94
chr1_+_68150744 0.286 ENST00000370986.4
ENST00000370985.3
GADD45A

growth arrest and DNA-damage-inducible, alpha

chr1_+_66820058 0.282 ENST00000480109.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr5_+_125798031 0.278 ENST00000502348.1
GRAMD3
GRAM domain containing 3
chr16_+_22517166 0.275 ENST00000356156.3
NPIPB5
nuclear pore complex interacting protein family, member B5
chr4_-_15939963 0.274 ENST00000259988.2
FGFBP1
fibroblast growth factor binding protein 1
chr16_-_66764119 0.273 ENST00000569320.1
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr12_-_12503156 0.271 ENST00000543314.1
ENST00000396349.3
MANSC1

MANSC domain containing 1

chr19_-_57678811 0.269 ENST00000554048.2
DUXA
double homeobox A
chr10_-_104866395 0.269 ENST00000458345.1
NT5C2
5'-nucleotidase, cytosolic II
chr16_+_24549014 0.269 ENST00000564314.1
ENST00000567686.1
RBBP6

retinoblastoma binding protein 6

chr5_+_89770696 0.265 ENST00000504930.1
ENST00000514483.1
POLR3G

polymerase (RNA) III (DNA directed) polypeptide G (32kD)

chr11_+_17281900 0.264 ENST00000530527.1
NUCB2
nucleobindin 2
chr8_+_92114060 0.264 ENST00000518304.1
LRRC69
leucine rich repeat containing 69
chr12_+_76653611 0.262 ENST00000550380.1
RP11-54A9.1
RP11-54A9.1
chr8_+_92114873 0.262 ENST00000343709.3
ENST00000448384.2
LRRC69

leucine rich repeat containing 69

chr2_-_101925055 0.262 ENST00000295317.3
RNF149
ring finger protein 149
chr19_-_47291843 0.260 ENST00000542575.2
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr15_+_89164560 0.254 ENST00000379231.3
ENST00000559528.1
AEN

apoptosis enhancing nuclease

chr6_+_71104588 0.253 ENST00000418403.1
RP11-462G2.1
RP11-462G2.1
chr1_+_81106951 0.252 ENST00000443565.1
RP5-887A10.1
RP5-887A10.1
chr11_-_104827425 0.252 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr11_-_47546220 0.251 ENST00000528538.1
CELF1
CUGBP, Elav-like family member 1
chr3_-_194188956 0.251 ENST00000256031.4
ENST00000446356.1
ATP13A3

ATPase type 13A3

chr15_+_89164520 0.247 ENST00000332810.3
AEN
apoptosis enhancing nuclease
chr8_-_101571964 0.247 ENST00000520552.1
ENST00000521345.1
ENST00000523000.1
ENST00000335659.3
ENST00000358990.3
ENST00000519597.1
ANKRD46





ankyrin repeat domain 46





chr9_+_125133315 0.245 ENST00000223423.4
ENST00000362012.2
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr21_-_35016231 0.245 ENST00000438788.1
CRYZL1
crystallin, zeta (quinone reductase)-like 1
chr15_+_73976545 0.242 ENST00000318443.5
ENST00000537340.2
ENST00000318424.5
CD276


CD276 molecule


chr21_-_33957805 0.242 ENST00000300258.3
ENST00000472557.1
TCP10L

t-complex 10-like

chr3_-_156272872 0.241 ENST00000476217.1
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr12_+_14572070 0.240 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP




activating transcription factor 7 interacting protein




chr19_-_36822551 0.240 ENST00000591372.1
LINC00665
long intergenic non-protein coding RNA 665
chr2_-_151344172 0.238 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3


Rho family GTPase 3


chr20_+_30102231 0.237 ENST00000335574.5
ENST00000340852.5
ENST00000398174.3
ENST00000376127.3
ENST00000344042.5
HM13




histocompatibility (minor) 13




chr15_+_89631647 0.237 ENST00000569550.1
ENST00000565066.1
ENST00000565973.1
ABHD2


abhydrolase domain containing 2


chr4_+_79567057 0.236 ENST00000503259.1
ENST00000507802.1
RP11-792D21.2

long intergenic non-protein coding RNA 1094

chr8_-_30670384 0.235 ENST00000221138.4
ENST00000518243.1
PPP2CB

protein phosphatase 2, catalytic subunit, beta isozyme

chr1_-_146989697 0.233 ENST00000437831.1
LINC00624
long intergenic non-protein coding RNA 624
chr11_+_101983176 0.230 ENST00000524575.1
YAP1
Yes-associated protein 1
chr19_+_35417939 0.230 ENST00000601142.1
ENST00000426813.2
ZNF30

zinc finger protein 30

chr12_-_102224457 0.230 ENST00000549165.1
ENST00000549940.1
ENST00000392919.4
GNPTAB


N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits


chr1_+_43291220 0.229 ENST00000372514.3
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr6_-_24646249 0.229 ENST00000430948.2
ENST00000537886.1
ENST00000535378.1
ENST00000378214.3
KIAA0319



KIAA0319



chrX_+_21958674 0.228 ENST00000404933.2
SMS
spermine synthase
chr10_-_128110441 0.223 ENST00000456514.1
LINC00601
long intergenic non-protein coding RNA 601
chr9_-_86955598 0.223 ENST00000376238.4
SLC28A3
solute carrier family 28 (concentrative nucleoside transporter), member 3
chr17_-_15554940 0.222 ENST00000455584.2
RP11-385D13.1
Uncharacterized protein
chr9_+_108463234 0.221 ENST00000374688.1
TMEM38B
transmembrane protein 38B
chr10_-_28571015 0.220 ENST00000375719.3
ENST00000375732.1
MPP7

membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)

chr1_+_160370344 0.220 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chrX_+_1387721 0.220 ENST00000419094.1
ENST00000381509.3
ENST00000494969.2
ENST00000355805.2
ENST00000355432.3
CSF2RA




colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)




chr3_-_37216055 0.220 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr2_+_161993412 0.220 ENST00000259075.2
ENST00000432002.1
TANK

TRAF family member-associated NFKB activator

chrX_+_1387693 0.219 ENST00000381529.3
ENST00000432318.2
ENST00000361536.3
ENST00000501036.2
ENST00000381524.3
ENST00000412290.1
CSF2RA





colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)





chr9_+_125132803 0.219 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr11_-_3400330 0.219 ENST00000427810.2
ENST00000005082.9
ENST00000534569.1
ENST00000438262.2
ENST00000528796.1
ENST00000528410.1
ENST00000529678.1
ENST00000354599.6
ENST00000526601.1
ENST00000525502.1
ENST00000533036.1
ENST00000399602.4
ZNF195











zinc finger protein 195











chr12_-_70093190 0.219 ENST00000330891.5
BEST3
bestrophin 3
chr6_-_138060103 0.218 ENST00000411615.1
ENST00000419220.1
RP11-356I2.1

RP11-356I2.1

chr7_+_138943265 0.217 ENST00000483726.1
UBN2
ubinuclein 2
chr5_-_96518907 0.217 ENST00000508447.1
ENST00000283109.3
RIOK2

RIO kinase 2

chr16_+_15489629 0.216 ENST00000396385.3
MPV17L
MPV17 mitochondrial membrane protein-like
chr14_-_106926724 0.216 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr1_-_156571254 0.216 ENST00000438976.2
ENST00000334588.7
ENST00000368232.4
ENST00000415314.2
GPATCH4



G patch domain containing 4



chr5_-_94417314 0.215 ENST00000505208.1
MCTP1
multiple C2 domains, transmembrane 1
chr18_+_61445205 0.214 ENST00000431370.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr6_-_112575687 0.213 ENST00000521398.1
ENST00000424408.2
ENST00000243219.3
LAMA4


laminin, alpha 4


chr3_+_156799587 0.213 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr4_+_100737954 0.212 ENST00000296414.7
ENST00000512369.1
DAPP1

dual adaptor of phosphotyrosine and 3-phosphoinositides

chrX_+_55744166 0.211 ENST00000374941.4
ENST00000414239.1
RRAGB

Ras-related GTP binding B

chr11_+_35198243 0.209 ENST00000528455.1
CD44
CD44 molecule (Indian blood group)
chr12_+_113344811 0.209 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
OAS1


2'-5'-oligoadenylate synthetase 1, 40/46kDa


chr12_+_75874984 0.209 ENST00000550491.1
GLIPR1
GLI pathogenesis-related 1
chr5_+_68860949 0.209 ENST00000507595.1
GTF2H2C
general transcription factor IIH, polypeptide 2C
chr10_+_51549498 0.208 ENST00000358559.2
ENST00000298239.6
MSMB

microseminoprotein, beta-

chr16_+_14805546 0.207 ENST00000552140.1
NPIPA3
nuclear pore complex interacting protein family, member A3
chr11_-_4414880 0.206 ENST00000254436.7
ENST00000543625.1
TRIM21

tripartite motif containing 21

chr8_-_62559366 0.206 ENST00000522919.1
ASPH
aspartate beta-hydroxylase
chr1_-_109618566 0.206 ENST00000338366.5
TAF13
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr12_-_102224704 0.205 ENST00000299314.7
GNPTAB
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr19_-_22379753 0.205 ENST00000397121.2
ZNF676
zinc finger protein 676
chrX_+_55744228 0.204 ENST00000262850.7
RRAGB
Ras-related GTP binding B
chr8_-_90996837 0.204 ENST00000519426.1
ENST00000265433.3
NBN

nibrin

chr12_+_20963632 0.203 ENST00000540853.1
ENST00000261196.2
SLCO1B3

solute carrier organic anion transporter family, member 1B3

chr1_-_207226313 0.203 ENST00000367084.1
YOD1
YOD1 deubiquitinase
chr7_-_33102399 0.203 ENST00000242210.7
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr1_-_193075180 0.202 ENST00000367440.3
GLRX2
glutaredoxin 2
chr6_-_112575758 0.202 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
LAMA4



laminin, alpha 4



chr2_-_86333244 0.201 ENST00000263857.6
ENST00000409681.1
POLR1A

polymerase (RNA) I polypeptide A, 194kDa

chr1_+_158978768 0.200 ENST00000447473.2
IFI16
interferon, gamma-inducible protein 16
chr4_+_78829479 0.200 ENST00000504901.1
MRPL1
mitochondrial ribosomal protein L1
chr17_-_40170506 0.200 ENST00000589773.1
ENST00000590348.1
DNAJC7

DnaJ (Hsp40) homolog, subfamily C, member 7

chr14_+_62164340 0.199 ENST00000557538.1
ENST00000539097.1
HIF1A

hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

chr3_+_10206545 0.199 ENST00000256458.4
IRAK2
interleukin-1 receptor-associated kinase 2
chr3_-_107099454 0.198 ENST00000593837.1
ENST00000599431.1
RP11-446H18.5

RP11-446H18.5

chr17_+_7482785 0.198 ENST00000250092.6
ENST00000380498.6
ENST00000584502.1
CD68


CD68 molecule


chr11_+_29181503 0.198 ENST00000530960.1
RP11-466I1.1
RP11-466I1.1
chrM_+_10464 0.197 ENST00000361335.1
MT-ND4L
mitochondrially encoded NADH dehydrogenase 4L
chr2_+_228735763 0.197 ENST00000373666.2
DAW1
dynein assembly factor with WDR repeat domains 1
chr14_+_65878565 0.197 ENST00000556518.1
ENST00000557164.1
FUT8

fucosyltransferase 8 (alpha (1,6) fucosyltransferase)

chr17_+_41132564 0.196 ENST00000361677.1
ENST00000589705.1
RUNDC1

RUN domain containing 1

chr6_-_112575912 0.196 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4


laminin, alpha 4


chr15_-_78913628 0.196 ENST00000348639.3
CHRNA3
cholinergic receptor, nicotinic, alpha 3 (neuronal)
chr11_-_124670550 0.196 ENST00000239614.4
MSANTD2
Myb/SANT-like DNA-binding domain containing 2
chr11_+_125462690 0.194 ENST00000392708.4
ENST00000529196.1
ENST00000531491.1
STT3A


STT3A, subunit of the oligosaccharyltransferase complex (catalytic)



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.5 1.4 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.3 10.2 GO:0045730 respiratory burst(GO:0045730)
0.2 1.7 GO:0071461 cellular response to redox state(GO:0071461)
0.2 2.8 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.2 0.6 GO:0036451 cap mRNA methylation(GO:0036451)
0.2 0.8 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.2 1.5 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.4 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 2.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.9 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.4 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 0.4 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.4 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 0.5 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.3 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.1 0.3 GO:0071790 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.1 0.8 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.4 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.1 0.4 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.1 GO:0030316 osteoclast differentiation(GO:0030316)
0.1 1.1 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 0.3 GO:0002316 follicular B cell differentiation(GO:0002316)
0.1 0.5 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.2 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 0.4 GO:0043686 co-translational protein modification(GO:0043686)
0.1 0.1 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.1 0.2 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.3 GO:0036071 N-glycan fucosylation(GO:0036071)
0.1 0.3 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.7 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.3 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 0.2 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 0.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.4 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.4 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.2 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.2 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.1 0.1 GO:0043467 regulation of cellular respiration(GO:0043457) regulation of generation of precursor metabolites and energy(GO:0043467)
0.1 0.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.2 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.1 0.5 GO:0003383 apical constriction(GO:0003383)
0.1 0.3 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.3 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.2 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.1 0.6 GO:0015889 cobalamin transport(GO:0015889)
0.0 1.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.5 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.0 0.7 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.2 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.2 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.3 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.4 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.2 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.1 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.0 0.6 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.3 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.9 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0052214 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.6 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.0 0.2 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.1 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.1 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.0 0.2 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101) RNA repair(GO:0042245)
0.0 0.2 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:0097114 NMDA glutamate receptor clustering(GO:0097114)
0.0 0.2 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.0 0.1 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.1 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.4 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.3 GO:0042262 DNA protection(GO:0042262)
0.0 0.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.2 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.2 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.0 GO:0006789 bilirubin conjugation(GO:0006789)
0.0 0.5 GO:0007620 copulation(GO:0007620)
0.0 0.1 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.2 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.0 GO:0072025 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.0 0.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.6 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.2 GO:0034699 response to luteinizing hormone(GO:0034699)
0.0 0.2 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0033864 positive regulation of NAD(P)H oxidase activity(GO:0033864) flavin-containing compound biosynthetic process(GO:0042727)
0.0 0.0 GO:0001960 negative regulation of cytokine-mediated signaling pathway(GO:0001960) negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804) negative regulation of response to cytokine stimulus(GO:0060761)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.1 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.2 GO:0050893 sensory processing(GO:0050893)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.0 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.1 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0 0.1 GO:0007037 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.0 0.1 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0 0.6 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.4 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.0 GO:0006203 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 0.0 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.1 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.0 0.2 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.1 GO:1904585 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.8 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.1 GO:1904685 positive regulation of metalloendopeptidase activity(GO:1904685)
0.0 0.3 GO:0001780 neutrophil homeostasis(GO:0001780)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.0 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.0 0.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.1 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.2 GO:0010911 phosphatidylserine biosynthetic process(GO:0006659) regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.0 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.0 0.1 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.6 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.5 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.2 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.1 GO:0032916 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) negative regulation of lung blood pressure(GO:0061767)
0.0 0.2 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.0 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.1 GO:0046495 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.1 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.0 0.0 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.2 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.0 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.0 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.0 0.2 GO:0009615 response to virus(GO:0009615)
0.0 0.1 GO:0042335 cuticle development(GO:0042335)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:0071047 nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.0 0.2 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0034776 response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.0 0.4 GO:0042755 eating behavior(GO:0042755)
0.0 0.0 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.2 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.2 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.0 0.0 GO:0070972 protein localization to endoplasmic reticulum(GO:0070972)
0.0 0.4 GO:0016246 RNA interference(GO:0016246)
0.0 0.1 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.2 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.0 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:0016050 vesicle organization(GO:0016050)
0.0 0.0 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 1.3 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.2 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.0 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.4 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.1 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.1 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.6 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.1 GO:1903333 negative regulation of protein folding(GO:1903333)
0.0 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.2 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.0 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.0 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.0 0.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.0 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.0 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.3 GO:0006413 translational initiation(GO:0006413)
0.0 0.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.0 GO:0021896 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897) gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.1 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.1 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.0 GO:2000674 regulation of type B pancreatic cell apoptotic process(GO:2000674)
0.0 0.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.1 GO:0033504 floor plate development(GO:0033504)
0.0 0.2 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.0 GO:0021522 cell differentiation in spinal cord(GO:0021515) ventral spinal cord development(GO:0021517) spinal cord motor neuron differentiation(GO:0021522)
0.0 0.2 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.0 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:0001765 membrane raft assembly(GO:0001765)
0.0 0.4 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 9.9 GO:0032010 phagolysosome(GO:0032010)
0.2 1.5 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.3 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.1 0.4 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 0.6 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.1 0.2 GO:0070993 translation preinitiation complex(GO:0070993)
0.1 0.4 GO:0044194 cytolytic granule(GO:0044194)
0.1 0.2 GO:1990423 RZZ complex(GO:1990423)
0.0 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.1 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.0 0.2 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.6 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.3 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.1 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.7 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.4 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 2.3 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.0 GO:0035101 FACT complex(GO:0035101)
0.0 1.8 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.6 GO:0005605 basal lamina(GO:0005605)
0.0 0.1 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0090543 Flemming body(GO:0090543)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.0 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.0 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.6 9.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3 1.1 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.2 0.6 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.2 1.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.4 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.1 0.4 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 1.4 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.4 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 0.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.4 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.3 GO:0016768 spermine synthase activity(GO:0016768)
0.1 0.8 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 1.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.3 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.1 0.4 GO:0015389 pyrimidine nucleobase transmembrane transporter activity(GO:0005350) pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.1 0.4 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.9 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.3 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.3 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1 0.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.2 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 0.4 GO:0042835 BRE binding(GO:0042835)
0.1 0.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.2 GO:1904854 proteasome core complex binding(GO:1904854)
0.1 0.2 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.3 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 0.2 GO:0070283 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.1 0.2 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.2 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.0 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.6 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.3 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 2.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.0 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.0 0.4 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.2 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.3 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.3 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0019808 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.0 0.2 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0070996 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783) type 1 melanocortin receptor binding(GO:0070996)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.1 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.0 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.0 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.0 0.9 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.0 GO:0080084 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) 5S rDNA binding(GO:0080084)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0005115 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.0 0.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.0 GO:0005503 all-trans retinal binding(GO:0005503)
0.0 0.0 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0000182 rDNA binding(GO:0000182)
0.0 0.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.3 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.0 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 1.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.4 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.8 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 1.5 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.8 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 0.3 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 1.3 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 0.3 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.0 0.5 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 1.8 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 1.1 PID_ATM_PATHWAY ATM pathway
0.0 0.8 PID_GMCSF_PATHWAY GMCSF-mediated signaling events
0.0 0.2 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.1 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.1 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.5 ST_G_ALPHA_I_PATHWAY G alpha i Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.3 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.4 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.1 REACTOME_SIGNALING_BY_FGFR_IN_DISEASE Genes involved in Signaling by FGFR in disease
0.0 1.4 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.1 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 3.2 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 2.3 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.5 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.7 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.1 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 0.4 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.6 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.2 REACTOME_OPSINS Genes involved in Opsins
0.0 0.3 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.5 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.2 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.4 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks