Motif ID: DLX1_HOXA3_BARX2

Z-value: 0.483

Transcription factors associated with DLX1_HOXA3_BARX2:

Gene SymbolEntrez IDGene Name
BARX2 ENSG00000043039.5 BARX2
DLX1 ENSG00000144355.10 DLX1
HOXA3 ENSG00000105997.18 HOXA3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
DLX1hg19_v2_chr2_+_172950227_172950264-0.501.7e-01Click!
BARX2hg19_v2_chr11_+_129245796_129245835-0.491.8e-01Click!
HOXA3hg19_v2_chr7_-_27153454_271534690.393.0e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of DLX1_HOXA3_BARX2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_186570679 1.073 ENST00000451974.1
SORBS2
sorbin and SH3 domain containing 2
chr6_-_87804815 0.860 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chrX_-_13835147 0.722 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr17_+_67498538 0.538 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr2_+_191221240 0.507 ENST00000409027.1
ENST00000458193.1
INPP1

inositol polyphosphate-1-phosphatase

chr4_-_186696425 0.487 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2


sorbin and SH3 domain containing 2


chr10_+_18549645 0.383 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chrX_-_18690210 0.315 ENST00000379984.3
RS1
retinoschisin 1
chr18_-_33709268 0.299 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6


solute carrier family 39 (zinc transporter), member 6


chr2_-_43266680 0.274 ENST00000425212.1
ENST00000422351.1
ENST00000449766.1
AC016735.2


AC016735.2


chr12_+_7013897 0.262 ENST00000007969.8
ENST00000323702.5
LRRC23

leucine rich repeat containing 23

chr6_-_116866773 0.258 ENST00000368602.3
TRAPPC3L
trafficking protein particle complex 3-like
chr19_-_3557570 0.254 ENST00000355415.2
MFSD12
major facilitator superfamily domain containing 12
chr1_-_151798546 0.246 ENST00000356728.6
RORC
RAR-related orphan receptor C
chr4_-_186696561 0.234 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2





sorbin and SH3 domain containing 2





chr3_-_98235962 0.233 ENST00000513873.1
CLDND1
claudin domain containing 1
chr4_-_112993808 0.223 ENST00000511219.1
RP11-269F21.3
RP11-269F21.3
chr12_+_7014064 0.223 ENST00000443597.2
LRRC23
leucine rich repeat containing 23
chr11_+_112047087 0.219 ENST00000526088.1
ENST00000532593.1
ENST00000531169.1
BCO2


beta-carotene oxygenase 2


chr11_-_111649074 0.213 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr14_-_47351391 0.210 ENST00000399222.3
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr8_+_70476088 0.208 ENST00000525999.1
SULF1
sulfatase 1
chr17_+_48823896 0.189 ENST00000511974.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr8_+_70404996 0.187 ENST00000402687.4
ENST00000419716.3
SULF1

sulfatase 1

chr11_-_111649015 0.187 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr1_-_212965104 0.184 ENST00000422588.2
ENST00000366975.6
ENST00000366977.3
ENST00000366976.1
NSL1



NSL1, MIS12 kinetochore complex component



chr15_-_55657428 0.181 ENST00000568543.1
CCPG1
cell cycle progression 1
chr18_+_32173276 0.181 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA








dystrobrevin, alpha








chr2_-_183387064 0.181 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A



phosphodiesterase 1A, calmodulin-dependent



chr5_-_22853429 0.178 ENST00000504376.2
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr12_-_10605929 0.175 ENST00000347831.5
ENST00000359151.3
KLRC1

killer cell lectin-like receptor subfamily C, member 1

chr11_-_128894053 0.173 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr7_-_124569991 0.171 ENST00000446993.1
ENST00000357628.3
ENST00000393329.1
POT1


protection of telomeres 1


chr6_+_160542821 0.168 ENST00000366963.4
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr3_-_105587879 0.166 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
CBLB


Cbl proto-oncogene B, E3 ubiquitin protein ligase


chr1_+_197237352 0.165 ENST00000538660.1
ENST00000367400.3
ENST00000367399.2
CRB1


crumbs homolog 1 (Drosophila)


chr6_-_116833500 0.162 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr11_+_115498761 0.162 ENST00000424313.2
AP000997.1
AP000997.1
chr1_-_151804314 0.154 ENST00000318247.6
RORC
RAR-related orphan receptor C
chr5_+_36606700 0.150 ENST00000416645.2
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_-_105588231 0.150 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB




Cbl proto-oncogene B, E3 ubiquitin protein ligase




chr16_-_55866997 0.148 ENST00000360526.3
ENST00000361503.4
CES1

carboxylesterase 1

chr11_-_64684672 0.147 ENST00000377264.3
ENST00000421419.2
ATG2A

autophagy related 2A

chr20_-_50419055 0.144 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr14_-_92413353 0.143 ENST00000556154.1
FBLN5
fibulin 5
chr6_+_26440700 0.143 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3









butyrophilin, subfamily 3, member A3









chr1_-_201140673 0.141 ENST00000367333.2
TMEM9
transmembrane protein 9
chr4_-_186696515 0.141 ENST00000456596.1
ENST00000414724.1
SORBS2

sorbin and SH3 domain containing 2

chr6_+_26365443 0.140 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2





butyrophilin, subfamily 3, member A2





chr14_-_23426270 0.138 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS4



HAUS augmin-like complex, subunit 4



chr14_-_23426337 0.136 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS4






HAUS augmin-like complex, subunit 4






chr18_-_48351743 0.133 ENST00000588444.1
ENST00000256425.2
ENST00000428869.2
MRO


maestro


chr4_-_119759795 0.132 ENST00000419654.2
SEC24D
SEC24 family member D
chr1_+_70876926 0.131 ENST00000370938.3
ENST00000346806.2
CTH

cystathionase (cystathionine gamma-lyase)

chr12_-_719573 0.129 ENST00000397265.3
NINJ2
ninjurin 2
chr6_+_160542870 0.129 ENST00000324965.4
ENST00000457470.2
SLC22A1

solute carrier family 22 (organic cation transporter), member 1

chr6_+_26402517 0.127 ENST00000414912.2
BTN3A1
butyrophilin, subfamily 3, member A1
chr11_-_63376013 0.127 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr16_+_53412368 0.125 ENST00000565189.1
RP11-44F14.2
RP11-44F14.2
chr6_+_26365387 0.125 ENST00000532865.1
ENST00000530653.1
ENST00000527417.1
BTN3A2


butyrophilin, subfamily 3, member A2


chr12_-_8088871 0.125 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr20_-_50418947 0.125 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr20_-_50418972 0.124 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr16_-_30122717 0.123 ENST00000566613.1
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr17_-_73663245 0.123 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
RECQL5



RecQ protein-like 5



chr1_+_70876891 0.123 ENST00000411986.2
CTH
cystathionase (cystathionine gamma-lyase)
chr6_+_26402465 0.123 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1





butyrophilin, subfamily 3, member A1





chr14_-_23426322 0.123 ENST00000555367.1
HAUS4
HAUS augmin-like complex, subunit 4
chr14_-_23426231 0.121 ENST00000556915.1
HAUS4
HAUS augmin-like complex, subunit 4
chr2_-_183387430 0.120 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr5_+_36608280 0.120 ENST00000513646.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_-_171528227 0.120 ENST00000356327.5
ENST00000342215.6
ENST00000340989.4
ENST00000351298.4
PLD1



phospholipase D1, phosphatidylcholine-specific



chr8_+_107738343 0.119 ENST00000521592.1
OXR1
oxidation resistance 1
chr8_-_66474884 0.119 ENST00000520902.1
CTD-3025N20.2
CTD-3025N20.2
chr17_+_62223320 0.118 ENST00000580828.1
ENST00000582965.1
SNORA76

small nucleolar RNA, H/ACA box 76

chr18_-_48346415 0.116 ENST00000431965.2
ENST00000436348.2
MRO

maestro

chr21_+_40752378 0.116 ENST00000398753.1
ENST00000442773.1
WRB

tryptophan rich basic protein

chr6_+_160693591 0.113 ENST00000419196.1
RP1-276N6.2
RP1-276N6.2
chr12_+_7014126 0.113 ENST00000415834.1
ENST00000436789.1
LRRC23

leucine rich repeat containing 23

chr17_+_67498295 0.111 ENST00000589295.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr10_-_93392811 0.111 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr15_+_43985725 0.110 ENST00000413453.2
CKMT1A
creatine kinase, mitochondrial 1A
chr8_-_49834299 0.110 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr2_-_183387283 0.109 ENST00000435564.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr7_+_99717230 0.109 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chr15_+_41057818 0.109 ENST00000558467.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr7_-_111032971 0.106 ENST00000450877.1
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr2_+_202047596 0.103 ENST00000286186.6
ENST00000360132.3
CASP10

caspase 10, apoptosis-related cysteine peptidase

chr6_-_119670898 0.103 ENST00000368466.2
MAN1A1
mannosidase, alpha, class 1A, member 1
chr4_-_109541539 0.103 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34-AS1


RPL34 antisense RNA 1 (head to head)


chr3_+_151591422 0.102 ENST00000362032.5
SUCNR1
succinate receptor 1
chr18_+_46065393 0.099 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr3_+_111630451 0.099 ENST00000495180.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr3_-_98619999 0.099 ENST00000449482.1
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr15_+_43886057 0.098 ENST00000441322.1
ENST00000413657.2
ENST00000453733.1
CKMT1B


creatine kinase, mitochondrial 1B


chr5_+_115177178 0.098 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr3_-_191000172 0.098 ENST00000427544.2
UTS2B
urotensin 2B
chr11_-_129062093 0.098 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr1_+_196743943 0.097 ENST00000471440.2
ENST00000391985.3
CFHR3

complement factor H-related 3

chr2_+_202047843 0.096 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
CASP10




caspase 10, apoptosis-related cysteine peptidase




chr12_-_8088773 0.095 ENST00000544291.1
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr9_-_5830768 0.095 ENST00000381506.3
ERMP1
endoplasmic reticulum metallopeptidase 1
chr17_-_8198636 0.094 ENST00000577745.1
ENST00000579192.1
ENST00000396278.1
SLC25A35


solute carrier family 25, member 35


chr11_+_112041253 0.093 ENST00000532612.1
AP002884.3
AP002884.3
chr7_+_100860949 0.093 ENST00000305105.2
ZNHIT1
zinc finger, HIT-type containing 1
chr18_-_48346298 0.092 ENST00000398439.3
MRO
maestro
chr3_-_141747950 0.091 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr5_+_139554227 0.090 ENST00000261811.4
CYSTM1
cysteine-rich transmembrane module containing 1
chr17_+_67498396 0.089 ENST00000588110.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr7_-_28220354 0.089 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr10_-_97200772 0.088 ENST00000371241.1
ENST00000354106.3
ENST00000371239.1
ENST00000361941.3
ENST00000277982.5
ENST00000371245.3
SORBS1





sorbin and SH3 domain containing 1





chr6_+_24667257 0.088 ENST00000537591.1
ENST00000230048.4
ACOT13

acyl-CoA thioesterase 13

chr17_-_73663168 0.088 ENST00000578201.1
ENST00000423245.2
RECQL5

RecQ protein-like 5

chr19_+_9296279 0.088 ENST00000344248.2
OR7D2
olfactory receptor, family 7, subfamily D, member 2
chr7_+_142982023 0.087 ENST00000359333.3
ENST00000409244.1
ENST00000409541.1
ENST00000410004.1
TMEM139



transmembrane protein 139



chr8_+_105602961 0.087 ENST00000521923.1
RP11-127H5.1
Uncharacterized protein
chrX_-_138790348 0.085 ENST00000414978.1
ENST00000519895.1
MCF2

MCF.2 cell line derived transforming sequence

chr5_-_41794313 0.084 ENST00000512084.1
OXCT1
3-oxoacid CoA transferase 1
chr1_+_160370344 0.084 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr1_+_180601139 0.083 ENST00000367590.4
ENST00000367589.3
XPR1

xenotropic and polytropic retrovirus receptor 1

chr16_-_28634874 0.083 ENST00000395609.1
ENST00000350842.4
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr12_-_10282742 0.083 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A


C-type lectin domain family 7, member A


chr2_+_234826016 0.083 ENST00000324695.4
ENST00000433712.2
TRPM8

transient receptor potential cation channel, subfamily M, member 8

chr8_+_27238147 0.082 ENST00000412793.1
PTK2B
protein tyrosine kinase 2 beta
chr11_+_66276550 0.081 ENST00000419755.3
CTD-3074O7.11
Bardet-Biedl syndrome 1 protein
chr11_+_62496114 0.080 ENST00000532583.1
TTC9C
tetratricopeptide repeat domain 9C
chr12_-_10282836 0.079 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A


C-type lectin domain family 7, member A


chr22_-_29107919 0.079 ENST00000434810.1
ENST00000456369.1
CHEK2

checkpoint kinase 2

chr14_-_90085458 0.079 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3


forkhead box N3


chr1_+_207277632 0.078 ENST00000421786.1
C4BPA
complement component 4 binding protein, alpha
chr1_+_207277590 0.078 ENST00000367070.3
C4BPA
complement component 4 binding protein, alpha
chr10_+_35484793 0.077 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM




cAMP responsive element modulator




chr12_-_12714025 0.076 ENST00000539940.1
DUSP16
dual specificity phosphatase 16
chr11_-_8857248 0.076 ENST00000534248.1
ENST00000530959.1
ENST00000531578.1
ENST00000533225.1
ST5



suppression of tumorigenicity 5



chrX_-_16887963 0.076 ENST00000380084.4
RBBP7
retinoblastoma binding protein 7
chr12_-_10959892 0.075 ENST00000240615.2
TAS2R8
taste receptor, type 2, member 8
chr19_-_4535233 0.074 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5


perilipin 5


chr12_+_64798095 0.074 ENST00000332707.5
XPOT
exportin, tRNA
chr7_-_99717463 0.074 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr7_+_12544025 0.074 ENST00000443874.1
ENST00000424453.1
AC005281.1

AC005281.1

chr17_+_73452545 0.072 ENST00000314256.7
KIAA0195
KIAA0195
chr15_+_43885799 0.071 ENST00000449946.1
ENST00000417289.1
CKMT1B

creatine kinase, mitochondrial 1B

chr2_-_224467002 0.071 ENST00000421386.1
ENST00000433889.1
SCG2

secretogranin II

chr17_+_43238438 0.070 ENST00000593138.1
ENST00000586681.1
HEXIM2

hexamethylene bis-acetamide inducible 2

chr14_-_78083112 0.069 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr1_+_44679113 0.068 ENST00000361745.6
ENST00000446292.1
ENST00000440641.1
ENST00000436069.1
ENST00000437511.1
DMAP1




DNA methyltransferase 1 associated protein 1




chr5_+_36608422 0.068 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr12_-_14924056 0.067 ENST00000539745.1
HIST4H4
histone cluster 4, H4
chr1_+_62439037 0.067 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr7_+_120628731 0.067 ENST00000310396.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr16_-_25122735 0.066 ENST00000563176.1
RP11-449H11.1
RP11-449H11.1
chr12_+_48592134 0.066 ENST00000595310.1
DKFZP779L1853
DKFZP779L1853
chr6_-_38670897 0.066 ENST00000373365.4
GLO1
glyoxalase I
chrM_+_10053 0.066 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr5_-_141030943 0.066 ENST00000522783.1
ENST00000519800.1
ENST00000435817.2
FCHSD1


FCH and double SH3 domains 1


chr11_+_12399071 0.066 ENST00000539723.1
ENST00000550549.1
PARVA

parvin, alpha

chr8_+_101349823 0.065 ENST00000519566.1
KB-1991G8.1
KB-1991G8.1
chr6_+_125540951 0.065 ENST00000524679.1
TPD52L1
tumor protein D52-like 1
chr17_+_42264556 0.065 ENST00000319511.6
ENST00000589785.1
ENST00000592825.1
ENST00000589184.1
TMUB2



transmembrane and ubiquitin-like domain containing 2



chr5_+_140625147 0.064 ENST00000231173.3
PCDHB15
protocadherin beta 15
chr19_+_9203855 0.064 ENST00000429566.3
OR1M1
olfactory receptor, family 1, subfamily M, member 1
chr20_-_33735070 0.064 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2


ER degradation enhancer, mannosidase alpha-like 2


chr11_+_7618413 0.064 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr19_-_35264089 0.064 ENST00000588760.1
ENST00000329285.8
ENST00000587354.2
ZNF599


zinc finger protein 599


chr4_+_86396265 0.063 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr19_+_21579908 0.063 ENST00000596302.1
ENST00000392288.2
ENST00000594390.1
ENST00000355504.4
ZNF493



zinc finger protein 493



chr15_+_43986069 0.063 ENST00000415044.1
CKMT1A
creatine kinase, mitochondrial 1A
chr11_+_124134723 0.063 ENST00000524943.2
OR8G5
olfactory receptor, family 8, subfamily G, member 5
chr4_-_120243545 0.063 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr7_+_30589829 0.062 ENST00000579437.1
RP4-777O23.1
RP4-777O23.1
chr10_+_5135981 0.062 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr7_+_138915102 0.062 ENST00000486663.1
UBN2
ubinuclein 2
chr2_-_201729284 0.061 ENST00000434813.2
CLK1
CDC-like kinase 1
chr6_+_88106840 0.060 ENST00000369570.4
C6orf164
chromosome 6 open reading frame 164
chr7_-_99716952 0.060 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6










TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa










chr11_-_111794446 0.060 ENST00000527950.1
CRYAB
crystallin, alpha B
chr17_+_73539339 0.060 ENST00000581713.1
LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr17_+_79953310 0.059 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr19_+_40873617 0.059 ENST00000599353.1
PLD3
phospholipase D family, member 3
chr3_-_157217328 0.058 ENST00000392832.2
ENST00000543418.1
VEPH1

ventricular zone expressed PH domain-containing 1

chr19_-_49314269 0.057 ENST00000545387.2
ENST00000316273.6
ENST00000402551.1
ENST00000598162.1
ENST00000599246.1
BCAT2




branched chain amino-acid transaminase 2, mitochondrial




chr17_-_19364269 0.056 ENST00000421796.2
ENST00000585389.1
ENST00000609249.1
AC004448.5


AC004448.5


chr11_+_118398178 0.055 ENST00000302783.4
ENST00000539546.1
TTC36

tetratricopeptide repeat domain 36

chr9_+_125133467 0.055 ENST00000426608.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr8_-_116504448 0.055 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chr3_+_158519654 0.054 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
MFSD1


major facilitator superfamily domain containing 1


chr13_+_111748183 0.054 ENST00000422994.1
LINC00368
long intergenic non-protein coding RNA 368
chr2_-_201729393 0.054 ENST00000321356.4
CLK1
CDC-like kinase 1
chr11_-_327537 0.054 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chrX_-_138724994 0.054 ENST00000536274.1
MCF2
MCF.2 cell line derived transforming sequence
chr3_-_160823040 0.054 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
B3GALNT1






beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)






chr9_+_34652164 0.053 ENST00000441545.2
ENST00000553620.1
IL11RA

interleukin 11 receptor, alpha

chr5_+_66300464 0.053 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr11_+_76092353 0.053 ENST00000530460.1
ENST00000321844.4
RP11-111M22.2

Homo sapiens putative uncharacterized protein FLJ37770-like (LOC100506127), mRNA.

chr2_+_226273597 0.053 ENST00000409269.2
NYAP2
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr4_+_146539415 0.052 ENST00000281317.5
MMAA
methylmalonic aciduria (cobalamin deficiency) cblA type
chr4_-_109541610 0.051 ENST00000510212.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr16_-_25122785 0.051 ENST00000563962.1
ENST00000569920.1
RP11-449H11.1

RP11-449H11.1

chr9_-_28670283 0.051 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr15_+_49462397 0.050 ENST00000396509.2
GALK2
galactokinase 2

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.3 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.3 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 0.3 GO:0048241 epinephrine transport(GO:0048241)
0.1 0.2 GO:0042214 terpene metabolic process(GO:0042214)
0.1 0.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.2 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.1 0.7 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.2 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.4 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of high voltage-gated calcium channel activity(GO:1901843) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 2.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.3 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.1 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.0 0.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.0 0.1 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.1 GO:0006550 isoleucine catabolic process(GO:0006550)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.1 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0 0.1 GO:0006714 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.9 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.1 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.5 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.2 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.0 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.0 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.0 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.4 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.1 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.1 GO:1904177 ether lipid metabolic process(GO:0046485) regulation of adipose tissue development(GO:1904177)
0.0 0.0 GO:0035948 N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.0 GO:0061324 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.0 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.1 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.0 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 0.3 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.2 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 1.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.0 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.4 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0045550 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.0 0.1 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.0 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.0 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.8 REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10