Motif ID: CEBPE_CEBPD

Z-value: 0.689

Transcription factors associated with CEBPE_CEBPD:

Gene SymbolEntrez IDGene Name
CEBPD ENSG00000221869.4 CEBPD
CEBPE ENSG00000092067.5 CEBPE

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
CEBPEhg19_v2_chr14_-_23588816_235888360.412.8e-01Click!
CEBPDhg19_v2_chr8_-_48651648_486516480.186.5e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of CEBPE_CEBPD

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_22766766 2.448 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6






interleukin 6 (interferon, beta 2)






chr6_+_31895467 1.253 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr15_+_45926919 1.245 ENST00000561735.1
ENST00000260324.7
SQRDL

sulfide quinone reductase-like (yeast)

chr6_+_31895480 1.140 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2

CFB
complement component 2

Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr11_+_18287801 0.775 ENST00000532858.1
ENST00000405158.2
SAA1

serum amyloid A1

chrX_-_15620192 0.758 ENST00000427411.1
ACE2
angiotensin I converting enzyme 2
chr2_-_101925055 0.725 ENST00000295317.3
RNF149
ring finger protein 149
chr11_+_18287721 0.578 ENST00000356524.4
SAA1
serum amyloid A1
chr12_-_123201337 0.561 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr12_-_123187890 0.559 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr2_-_113594279 0.474 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B


interleukin 1, beta


chr11_-_18270182 0.451 ENST00000528349.1
ENST00000526900.1
ENST00000529528.1
ENST00000414546.2
ENST00000256733.4
SAA2




serum amyloid A2




chr5_+_36608422 0.413 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr20_-_17662878 0.387 ENST00000377813.1
ENST00000377807.2
ENST00000360807.4
ENST00000398782.2
RRBP1



ribosome binding protein 1



chr8_+_124194752 0.385 ENST00000318462.6
FAM83A
family with sequence similarity 83, member A
chr12_+_102271436 0.370 ENST00000544152.1
DRAM1
DNA-damage regulated autophagy modulator 1
chrX_-_73511908 0.359 ENST00000455395.1
FTX
FTX transcript, XIST regulator (non-protein coding)
chr8_+_124194875 0.349 ENST00000522648.1
ENST00000276699.6
FAM83A

family with sequence similarity 83, member A

chr12_+_102271129 0.316 ENST00000258534.8
DRAM1
DNA-damage regulated autophagy modulator 1
chr1_+_169079823 0.297 ENST00000367813.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr1_+_90308981 0.289 ENST00000527156.1
LRRC8D
leucine rich repeat containing 8 family, member D
chr2_-_61245363 0.276 ENST00000316752.6
PUS10
pseudouridylate synthase 10
chr5_+_95998070 0.258 ENST00000421689.2
ENST00000510756.1
ENST00000512620.1
CAST


calpastatin


chr5_+_95997885 0.249 ENST00000511097.2
CAST
calpastatin
chr3_-_148939835 0.248 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr9_-_130712995 0.235 ENST00000373084.4
FAM102A
family with sequence similarity 102, member A
chr12_-_12491608 0.228 ENST00000545735.1
MANSC1
MANSC domain containing 1
chr17_+_57287228 0.227 ENST00000578922.1
ENST00000300917.5
SMG8

SMG8 nonsense mediated mRNA decay factor

chr18_+_32621324 0.227 ENST00000300249.5
ENST00000538170.2
ENST00000588910.1
MAPRE2


microtubule-associated protein, RP/EB family, member 2


chr5_+_95997769 0.224 ENST00000338252.3
ENST00000508830.1
CAST

calpastatin

chr8_+_110552831 0.221 ENST00000530629.1
EBAG9
estrogen receptor binding site associated, antigen, 9
chr22_-_20731541 0.220 ENST00000292729.8
USP41
ubiquitin specific peptidase 41
chr8_+_77318769 0.211 ENST00000518732.1
RP11-706J10.1
long intergenic non-protein coding RNA 1111
chr10_+_17270214 0.207 ENST00000544301.1
VIM
vimentin
chr7_-_73153178 0.207 ENST00000437775.2
ENST00000222800.3
ABHD11

abhydrolase domain containing 11

chr5_-_131630931 0.201 ENST00000431054.1
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
chr3_+_11314072 0.194 ENST00000444619.1
ATG7
autophagy related 7
chr6_+_31515337 0.191 ENST00000376148.4
ENST00000376145.4
NFKBIL1

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1

chr21_+_33671264 0.182 ENST00000339944.4
MRAP
melanocortin 2 receptor accessory protein
chr17_-_61850894 0.180 ENST00000403162.3
ENST00000582252.1
ENST00000225726.5
CCDC47


coiled-coil domain containing 47


chr3_+_11314099 0.179 ENST00000446450.2
ENST00000354956.5
ENST00000354449.3
ENST00000419112.1
ATG7



autophagy related 7



chr14_+_20937538 0.178 ENST00000361505.5
ENST00000553591.1
PNP

purine nucleoside phosphorylase

chr5_+_95997918 0.174 ENST00000395812.2
ENST00000395813.1
ENST00000359176.4
ENST00000325674.7
CAST



calpastatin



chr11_+_62495997 0.173 ENST00000316461.4
TTC9C
tetratricopeptide repeat domain 9C
chr8_-_11324273 0.170 ENST00000284486.4
FAM167A
family with sequence similarity 167, member A
chr6_-_113754604 0.168 ENST00000421737.1
RP1-124C6.1
RP1-124C6.1
chr21_+_35736302 0.163 ENST00000290310.3
KCNE2
potassium voltage-gated channel, Isk-related family, member 2
chr8_+_110552337 0.161 ENST00000337573.5
EBAG9
estrogen receptor binding site associated, antigen, 9
chr15_+_63050785 0.160 ENST00000472902.1
TLN2
talin 2
chr3_+_11313995 0.159 ENST00000451513.1
ENST00000435760.1
ENST00000451830.1
ATG7


autophagy related 7


chr10_+_14880364 0.159 ENST00000441647.1
HSPA14
heat shock 70kDa protein 14
chr10_+_14880157 0.158 ENST00000378372.3
HSPA14
heat shock 70kDa protein 14
chr12_+_72058130 0.155 ENST00000547843.1
THAP2
THAP domain containing, apoptosis associated protein 2
chr11_+_62495541 0.152 ENST00000530625.1
ENST00000513247.2
TTC9C

tetratricopeptide repeat domain 9C

chr19_-_15443318 0.150 ENST00000360016.5
BRD4
bromodomain containing 4
chr16_-_84651647 0.148 ENST00000564057.1
COTL1
coactosin-like 1 (Dictyostelium)
chr10_-_22498950 0.147 ENST00000422359.2
EBLN1
endogenous Bornavirus-like nucleoprotein 1
chr4_-_139163491 0.146 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr16_-_84651673 0.145 ENST00000262428.4
COTL1
coactosin-like 1 (Dictyostelium)
chr11_+_82868030 0.145 ENST00000298281.4
ENST00000530660.1
PCF11

PCF11 cleavage and polyadenylation factor subunit

chr14_-_38028689 0.130 ENST00000553425.1
RP11-356O9.2
RP11-356O9.2
chr7_-_33080506 0.127 ENST00000381626.2
ENST00000409467.1
ENST00000449201.1
NT5C3A


5'-nucleotidase, cytosolic IIIA


chr17_-_2117600 0.125 ENST00000572369.1
SMG6
SMG6 nonsense mediated mRNA decay factor
chr8_-_102216925 0.125 ENST00000517844.1
ZNF706
zinc finger protein 706
chr19_-_1155118 0.125 ENST00000590998.1
SBNO2
strawberry notch homolog 2 (Drosophila)
chr17_+_61851504 0.122 ENST00000359353.5
ENST00000389924.2
DDX42

DEAD (Asp-Glu-Ala-Asp) box helicase 42

chr6_+_1389989 0.120 ENST00000259806.1
FOXF2
forkhead box F2
chr9_+_33290491 0.120 ENST00000379540.3
ENST00000379521.4
ENST00000318524.6
NFX1


nuclear transcription factor, X-box binding 1


chr10_+_90750493 0.119 ENST00000357339.2
ENST00000355279.2
FAS

Fas cell surface death receptor

chr2_-_216300784 0.119 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1













fibronectin 1













chr20_+_18125727 0.117 ENST00000489634.2
CSRP2BP
CSRP2 binding protein
chr2_-_68694390 0.116 ENST00000377957.3
FBXO48
F-box protein 48
chr9_+_110045418 0.116 ENST00000419616.1
RAD23B
RAD23 homolog B (S. cerevisiae)
chr19_-_15442701 0.115 ENST00000594841.1
ENST00000601941.1
BRD4

bromodomain containing 4

chr3_+_12392971 0.114 ENST00000287820.6
PPARG
peroxisome proliferator-activated receptor gamma
chr17_-_79817091 0.112 ENST00000570907.1
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr17_+_61851157 0.112 ENST00000578681.1
ENST00000583590.1
DDX42

DEAD (Asp-Glu-Ala-Asp) box helicase 42

chr17_+_7462031 0.111 ENST00000380535.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr11_+_82868185 0.111 ENST00000530304.1
ENST00000533018.1
PCF11

PCF11 cleavage and polyadenylation factor subunit

chrX_-_135962923 0.111 ENST00000565438.1
RBMX
RNA binding motif protein, X-linked
chr3_+_88188254 0.104 ENST00000309495.5
ZNF654
zinc finger protein 654
chrX_-_40506766 0.104 ENST00000378421.1
ENST00000440784.2
ENST00000327877.5
ENST00000378426.1
ENST00000378418.2
CXorf38




chromosome X open reading frame 38




chr2_-_157186630 0.101 ENST00000406048.2
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr10_+_90750378 0.099 ENST00000355740.2
ENST00000352159.4
FAS

Fas cell surface death receptor

chr12_-_96390108 0.097 ENST00000538703.1
ENST00000261208.3
HAL

histidine ammonia-lyase

chr6_+_108977520 0.096 ENST00000540898.1
FOXO3
forkhead box O3
chr21_-_39870339 0.095 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
ERG




v-ets avian erythroblastosis virus E26 oncogene homolog




chrX_-_135962876 0.089 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RBMX



RNA binding motif protein, X-linked



chr11_-_104905840 0.089 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1










caspase 1, apoptosis-related cysteine peptidase










chr7_-_105221898 0.088 ENST00000486180.1
ENST00000485614.1
ENST00000480514.1
EFCAB10


EF-hand calcium binding domain 10


chr2_+_102721023 0.088 ENST00000409589.1
ENST00000409329.1
IL1R1

interleukin 1 receptor, type I

chr10_-_14880002 0.087 ENST00000465530.1
CDNF
cerebral dopamine neurotrophic factor
chr9_-_99381660 0.084 ENST00000375240.3
ENST00000463569.1
CDC14B

cell division cycle 14B

chr7_-_73153161 0.084 ENST00000395147.4
ABHD11
abhydrolase domain containing 11
chr2_+_68694678 0.083 ENST00000303795.4
APLF
aprataxin and PNKP like factor
chr17_+_7462103 0.082 ENST00000396545.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr7_-_73153122 0.080 ENST00000458339.1
ABHD11
abhydrolase domain containing 11
chr15_+_81293254 0.080 ENST00000267984.2
MESDC1
mesoderm development candidate 1
chr2_+_87754989 0.080 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
LINC00152



long intergenic non-protein coding RNA 152



chr17_+_7477040 0.078 ENST00000581384.1
ENST00000577929.1
EIF4A1

eukaryotic translation initiation factor 4A1

chr21_+_38792602 0.077 ENST00000398960.2
ENST00000398956.2
DYRK1A

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

chr14_+_45464658 0.077 ENST00000555874.1
FAM179B
family with sequence similarity 179, member B
chr2_-_191878162 0.074 ENST00000540176.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr17_+_7461849 0.071 ENST00000338784.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr12_+_13197218 0.070 ENST00000197268.8
KIAA1467
KIAA1467
chr1_-_186649543 0.068 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr17_-_47755436 0.067 ENST00000505581.1
ENST00000514121.1
ENST00000393328.2
ENST00000509079.1
ENST00000393331.3
ENST00000347630.2
ENST00000504102.1
SPOP






speckle-type POZ protein






chr10_+_30723105 0.065 ENST00000375322.2
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr12_+_110940005 0.064 ENST00000409246.1
ENST00000392672.4
ENST00000409300.1
ENST00000409425.1
RAD9B



RAD9 homolog B (S. pombe)



chr1_-_156721502 0.062 ENST00000357325.5
HDGF
hepatoma-derived growth factor
chr8_-_42397037 0.062 ENST00000342228.3
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr1_-_6614565 0.061 ENST00000377705.5
NOL9
nucleolar protein 9
chr3_+_16306691 0.061 ENST00000285083.5
ENST00000605932.1
ENST00000435829.2
OXNAD1


oxidoreductase NAD-binding domain containing 1


chr13_+_41635617 0.060 ENST00000542082.1
WBP4
WW domain binding protein 4
chr6_-_86353510 0.060 ENST00000444272.1
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr11_-_8739383 0.060 ENST00000531060.1
ST5
suppression of tumorigenicity 5
chr17_+_7461781 0.060 ENST00000349228.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr11_-_10315741 0.060 ENST00000256190.8
SBF2
SET binding factor 2
chr12_+_26111823 0.059 ENST00000381352.3
ENST00000535907.1
ENST00000405154.2
RASSF8


Ras association (RalGDS/AF-6) domain family (N-terminal) member 8


chr17_-_77813186 0.058 ENST00000448310.1
ENST00000269397.4
CBX4

chromobox homolog 4

chr19_+_56989609 0.057 ENST00000601875.1
ZNF667-AS1
ZNF667 antisense RNA 1 (head to head)
chr11_-_77185094 0.055 ENST00000278568.4
ENST00000356341.3
PAK1

p21 protein (Cdc42/Rac)-activated kinase 1

chr17_+_73089382 0.055 ENST00000538213.2
ENST00000584118.1
SLC16A5

solute carrier family 16 (monocarboxylate transporter), member 5

chr19_+_45174724 0.054 ENST00000358777.4
CEACAM19
carcinoembryonic antigen-related cell adhesion molecule 19
chrX_-_73512177 0.054 ENST00000603672.1
ENST00000418855.1
FTX

FTX transcript, XIST regulator (non-protein coding)

chr9_+_110045537 0.054 ENST00000358015.3
RAD23B
RAD23 homolog B (S. cerevisiae)
chr14_+_61201445 0.053 ENST00000261245.4
ENST00000539616.2
MNAT1

MNAT CDK-activating kinase assembly factor 1

chr3_+_16306837 0.052 ENST00000606098.1
OXNAD1
oxidoreductase NAD-binding domain containing 1
chr14_+_36295504 0.052 ENST00000216807.7
BRMS1L
breast cancer metastasis-suppressor 1-like
chr11_-_47447767 0.051 ENST00000530651.1
ENST00000524447.2
ENST00000531051.2
ENST00000526993.1
ENST00000602866.1
PSMC3




proteasome (prosome, macropain) 26S subunit, ATPase, 3




chr16_+_3507985 0.051 ENST00000421765.3
ENST00000360862.5
ENST00000414063.2
ENST00000610180.1
ENST00000608993.1
NAA60


NAA60

N(alpha)-acetyltransferase 60, NatF catalytic subunit


N-alpha-acetyltransferase 60

chr17_+_72426891 0.051 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr11_-_104972158 0.051 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1



CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase



caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr4_+_95128996 0.050 ENST00000457823.2
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr6_+_37321748 0.050 ENST00000373479.4
ENST00000394443.4
RNF8

ring finger protein 8, E3 ubiquitin protein ligase

chr16_-_30457048 0.050 ENST00000500504.2
ENST00000542752.1
SEPHS2

selenophosphate synthetase 2

chr19_+_48949087 0.049 ENST00000598711.1
GRWD1
glutamate-rich WD repeat containing 1
chr17_+_27181956 0.049 ENST00000254928.5
ENST00000580917.2
ERAL1

Era-like 12S mitochondrial rRNA chaperone 1

chr3_+_130569429 0.049 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1



ATPase, Ca++ transporting, type 2C, member 1



chr13_-_24471641 0.049 ENST00000382145.1
C1QTNF9B
C1q and tumor necrosis factor related protein 9B
chr11_-_47447970 0.047 ENST00000298852.3
ENST00000530912.1
PSMC3

proteasome (prosome, macropain) 26S subunit, ATPase, 3

chr17_-_60142609 0.047 ENST00000397786.2
MED13
mediator complex subunit 13
chr20_-_33732952 0.045 ENST00000541621.1
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr4_+_95129061 0.045 ENST00000354268.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr3_-_10547192 0.045 ENST00000360273.2
ENST00000343816.4
ATP2B2

ATPase, Ca++ transporting, plasma membrane 2

chr17_+_72427477 0.045 ENST00000342648.5
ENST00000481232.1
GPRC5C

G protein-coupled receptor, family C, group 5, member C

chr10_+_60028818 0.045 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr19_-_41945804 0.043 ENST00000221943.9
ENST00000597457.1
ENST00000589970.1
ENST00000595425.1
ENST00000438807.3
ENST00000589102.1
ENST00000592922.2
ATP5SL






ATP5S-like






chr1_+_162531294 0.043 ENST00000367926.4
ENST00000271469.3
UAP1

UDP-N-acteylglucosamine pyrophosphorylase 1

chr17_-_41277370 0.042 ENST00000476777.1
ENST00000491747.2
ENST00000478531.1
ENST00000477152.1
ENST00000357654.3
ENST00000493795.1
ENST00000493919.1
BRCA1






breast cancer 1, early onset






chrX_-_73512411 0.041 ENST00000602576.1
ENST00000429124.1
FTX

FTX transcript, XIST regulator (non-protein coding)

chr19_+_48949030 0.041 ENST00000253237.5
GRWD1
glutamate-rich WD repeat containing 1
chr2_+_87755054 0.041 ENST00000423846.1
LINC00152
long intergenic non-protein coding RNA 152
chr4_+_95128748 0.040 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr8_-_25315905 0.039 ENST00000221200.4
KCTD9
potassium channel tetramerization domain containing 9
chr5_-_10761206 0.038 ENST00000432074.2
ENST00000230895.6
DAP

death-associated protein

chr7_-_121944491 0.037 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1


FEZ family zinc finger 1


chr8_+_71485681 0.037 ENST00000391684.1
AC120194.1
AC120194.1
chr17_-_41277467 0.037 ENST00000494123.1
ENST00000346315.3
ENST00000309486.4
ENST00000468300.1
ENST00000354071.3
ENST00000352993.3
ENST00000471181.2
BRCA1






breast cancer 1, early onset






chr13_-_46679144 0.037 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr14_-_70263979 0.037 ENST00000216540.4
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr11_-_105948129 0.037 ENST00000526793.1
KBTBD3
kelch repeat and BTB (POZ) domain containing 3
chr1_+_207262170 0.036 ENST00000367078.3
C4BPB
complement component 4 binding protein, beta
chr8_+_8559406 0.036 ENST00000519106.1
CLDN23
claudin 23
chr12_+_32638897 0.035 ENST00000531134.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr10_-_92681033 0.034 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr10_+_43916052 0.034 ENST00000442526.2
RP11-517P14.2
RP11-517P14.2
chr2_+_87754887 0.034 ENST00000409054.1
ENST00000331944.6
ENST00000409139.1
LINC00152


long intergenic non-protein coding RNA 152


chr20_-_60294804 0.032 ENST00000317652.1
RP11-429E11.3
Uncharacterized protein
chr14_+_58765103 0.032 ENST00000355431.3
ENST00000348476.3
ENST00000395168.3
ARID4A


AT rich interactive domain 4A (RBP1-like)


chr19_+_39903185 0.031 ENST00000409794.3
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr1_+_196743912 0.030 ENST00000367425.4
CFHR3
complement factor H-related 3
chr1_+_40862501 0.030 ENST00000539317.1
SMAP2
small ArfGAP2
chr17_-_41277317 0.030 ENST00000497488.1
ENST00000489037.1
ENST00000470026.1
ENST00000586385.1
ENST00000591534.1
ENST00000591849.1
BRCA1





breast cancer 1, early onset





chr12_-_96390063 0.029 ENST00000541929.1
HAL
histidine ammonia-lyase
chr4_-_114682224 0.028 ENST00000342666.5
ENST00000515496.1
ENST00000514328.1
ENST00000508738.1
ENST00000379773.2
CAMK2D




calcium/calmodulin-dependent protein kinase II delta




chr3_+_136649311 0.028 ENST00000469404.1
ENST00000467911.1
NCK1

NCK adaptor protein 1

chr4_-_103746683 0.027 ENST00000504211.1
ENST00000508476.1
UBE2D3

ubiquitin-conjugating enzyme E2D 3

chr3_+_101504200 0.027 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr13_-_46679185 0.026 ENST00000439329.3
CPB2
carboxypeptidase B2 (plasma)
chr3_-_158450231 0.026 ENST00000479756.1
RARRES1
retinoic acid receptor responder (tazarotene induced) 1
chr3_+_158450143 0.026 ENST00000491804.1
MFSD1
major facilitator superfamily domain containing 1
chr1_+_161087873 0.025 ENST00000368009.2
ENST00000368007.4
ENST00000368008.1
ENST00000392190.5
NIT1



nitrilase 1



chr4_-_103746924 0.025 ENST00000505207.1
ENST00000502404.1
ENST00000507845.1
UBE2D3


ubiquitin-conjugating enzyme E2D 3


chr12_+_110940111 0.024 ENST00000409778.3
RAD9B
RAD9 homolog B (S. pombe)
chr2_-_191885686 0.022 ENST00000432058.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr1_-_151032040 0.022 ENST00000540998.1
ENST00000357235.5
CDC42SE1

CDC42 small effector 1

chr20_-_39946237 0.020 ENST00000441102.2
ENST00000559234.1
ZHX3

zinc fingers and homeoboxes 3

chrX_-_119445306 0.019 ENST00000371369.4
ENST00000440464.1
ENST00000519908.1
TMEM255A


transmembrane protein 255A


chr8_+_24151553 0.019 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28


ADAM metallopeptidase domain 28


chr3_-_122233723 0.019 ENST00000493510.1
ENST00000344337.6
ENST00000476916.1
ENST00000465882.1
KPNA1



karyopherin alpha 1 (importin alpha 5)



chr17_+_7348658 0.019 ENST00000570557.1
ENST00000536404.2
ENST00000576360.1
CHRNB1


cholinergic receptor, nicotinic, beta 1 (muscle)


chr20_+_32150140 0.019 ENST00000344201.3
ENST00000346541.3
ENST00000397800.1
ENST00000397798.2
ENST00000492345.1
CBFA2T2




core-binding factor, runt domain, alpha subunit 2; translocated to, 2




chr17_+_2699697 0.019 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
RAP1GAP2


RAP1 GTPase activating protein 2


chr19_+_56989485 0.019 ENST00000585445.1
ENST00000586091.1
ENST00000594783.1
ENST00000592146.1
ENST00000588158.1
ENST00000299997.4
ENST00000591797.1
ZNF667-AS1






ZNF667 antisense RNA 1 (head to head)






chr1_+_245133278 0.019 ENST00000366522.2
EFCAB2
EF-hand calcium binding domain 2
chr1_-_67519782 0.019 ENST00000235345.5
SLC35D1
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
chr2_-_191878681 0.018 ENST00000409465.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr19_+_859425 0.018 ENST00000327726.6
CFD
complement factor D (adipsin)
chr4_+_96012614 0.017 ENST00000264568.4
BMPR1B
bone morphogenetic protein receptor, type IB

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.2 0.5 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521)
0.2 0.8 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.1 2.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.0 GO:0070162 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
0.1 0.2 GO:0046495 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.1 0.9 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1 0.3 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.3 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.0 0.4 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.2 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.0 0.1 GO:1904235 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.0 0.1 GO:0070512 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.1 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.1 GO:2000697 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.1 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.2 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 1.3 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.0 0.1 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.3 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of fibroblast growth factor production(GO:0090271) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.0 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.3 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.2 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.1 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.1 GO:2000674 regulation of type B pancreatic cell apoptotic process(GO:2000674)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 1.3 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.2 GO:0071942 XPC complex(GO:0071942)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.1 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 0.5 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 0.8 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.9 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 2.2 GO:0001848 complement binding(GO:0001848)
0.1 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.1 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.0 0.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 1.7 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.7 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.1 GO:0070996 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783) type 1 melanocortin receptor binding(GO:0070996)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.0 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.5 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.0 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 ST_STAT3_PATHWAY STAT3 Pathway
0.1 2.4 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 1.4 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.6 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 0.1 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.9 REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.4 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 1.2 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism