• All motifs sorted by activity significance
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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: CBFB

Z-value: 0.349

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_+_35856951	0.729	ENST00000303115.3 ENST00000343305.4 ENST00000506850.1 ENST00000511982.1	IL7R	interleukin 7 receptor
chr17_+_32582293	0.404	ENST00000580907.1 ENST00000225831.4	CCL2	chemokine (C-C motif) ligand 2
chr15_+_67390920	0.254	ENST00000559092.1 ENST00000560175.1	SMAD3	SMAD family member 3
chr1_-_179112173	0.186	ENST00000408940.3 ENST00000504405.1	ABL2	c-abl oncogene 2, non-receptor tyrosine kinase
chr1_-_179112189	0.182	ENST00000512653.1 ENST00000344730.3	ABL2	c-abl oncogene 2, non-receptor tyrosine kinase
chr13_+_76210448	0.174	ENST00000377499.5	LMO7	LIM domain 7
chr1_+_66796401	0.140	ENST00000528771.1	PDE4B	phosphodiesterase 4B, cAMP-specific
chr6_+_45296391	0.125	ENST00000371436.6 ENST00000576263.1	RUNX2	runt-related transcription factor 2
chr1_-_157014865	0.117	ENST00000361409.2	ARHGEF11	Rho guanine nucleotide exchange factor (GEF) 11
chr3_-_189840223	0.114	ENST00000427335.2	LEPREL1	leprecan-like 1
chr22_+_42665742	0.097	ENST00000332965.3 ENST00000415205.1 ENST00000446578.1	Z83851.3	Z83851.3
chrX_-_153718988	0.096	ENST00000263512.4 ENST00000393587.4 ENST00000453912.1	SLC10A3	solute carrier family 10, member 3
chr21_-_36421535	0.093	ENST00000416754.1 ENST00000437180.1 ENST00000455571.1	RUNX1	runt-related transcription factor 1
chr12_-_52585765	0.091	ENST00000313234.5 ENST00000394815.2	KRT80	keratin 80
chr2_+_173955327	0.090	ENST00000422149.1	MLTK	Mitogen-activated protein kinase kinase kinase MLT
chr2_-_64881018	0.088	ENST00000313349.3	SERTAD2	SERTA domain containing 2
chr1_-_184723942	0.087	ENST00000318130.8	EDEM3	ER degradation enhancer, mannosidase alpha-like 3
chr5_-_137878887	0.087	ENST00000507939.1 ENST00000572514.1 ENST00000499810.2 ENST00000360541.5	ETF1	eukaryotic translation termination factor 1
chr21_-_36421626	0.084	ENST00000300305.3	RUNX1	runt-related transcription factor 1
chr11_-_66104237	0.081	ENST00000530056.1	RIN1	Ras and Rab interactor 1
chr6_+_42847649	0.079	ENST00000424341.2 ENST00000602561.1	RPL7L1	ribosomal protein L7-like 1
chr6_-_75912508	0.075	ENST00000416123.2	COL12A1	collagen, type XII, alpha 1
chr11_-_66103932	0.070	ENST00000311320.4	RIN1	Ras and Rab interactor 1
chr14_-_61116168	0.068	ENST00000247182.6	SIX1	SIX homeobox 1
chr17_+_75316336	0.068	ENST00000591934.1	SEPT9	septin 9
chrX_+_68048803	0.063	ENST00000204961.4	EFNB1	ephrin-B1
chr6_+_27925019	0.063	ENST00000244623.1	OR2B6	olfactory receptor, family 2, subfamily B, member 6
chr10_-_29811456	0.059	ENST00000535393.1	SVIL	supervillin
chr19_+_10541462	0.055	ENST00000293683.5	PDE4A	phosphodiesterase 4A, cAMP-specific
chr3_+_156799587	0.046	ENST00000469196.1	RP11-6F2.5	RP11-6F2.5
chr11_-_9781068	0.046	ENST00000500698.1	RP11-540A21.2	RP11-540A21.2
chr11_-_66103867	0.044	ENST00000424433.2	RIN1	Ras and Rab interactor 1
chrX_-_19688475	0.042	ENST00000541422.1	SH3KBP1	SH3-domain kinase binding protein 1
chrX_-_49041242	0.042	ENST00000453382.1 ENST00000540849.1 ENST00000536904.1 ENST00000432913.1	PRICKLE3	prickle homolog 3 (Drosophila)
chr19_-_14048804	0.038	ENST00000254320.3 ENST00000586075.1	PODNL1	podocan-like 1
chr7_+_7196565	0.036	ENST00000429911.1	C1GALT1	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr11_-_58343319	0.035	ENST00000395074.2	LPXN	leupaxin
chr9_+_15422702	0.034	ENST00000380821.3 ENST00000421710.1	SNAPC3	small nuclear RNA activating complex, polypeptide 3, 50kDa
chr1_-_52499443	0.029	ENST00000371614.1	KTI12	KTI12 homolog, chromatin associated (S. cerevisiae)
chr17_+_1633755	0.026	ENST00000545662.1	WDR81	WD repeat domain 81
chr19_-_14049184	0.024	ENST00000339560.5	PODNL1	podocan-like 1
chr5_+_131409476	0.024	ENST00000296871.2	CSF2	colony stimulating factor 2 (granulocyte-macrophage)
chr2_+_68592305	0.023	ENST00000234313.7	PLEK	pleckstrin
chr16_+_53088885	0.023	ENST00000566029.1 ENST00000447540.1	CHD9	chromodomain helicase DNA binding protein 9
chr20_+_44637526	0.022	ENST00000372330.3	MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr6_-_152623231	0.021	ENST00000540663.1 ENST00000537033.1	SYNE1	spectrin repeat containing, nuclear envelope 1
chr2_+_103035102	0.021	ENST00000264260.2	IL18RAP	interleukin 18 receptor accessory protein
chr15_+_73976545	0.020	ENST00000318443.5 ENST00000537340.2 ENST00000318424.5	CD276	CD276 molecule
chr9_-_123342415	0.017	ENST00000349780.4 ENST00000360190.4 ENST00000360822.3 ENST00000359309.3	CDK5RAP2	CDK5 regulatory subunit associated protein 2
chr11_-_18343725	0.017	ENST00000531848.1	HPS5	Hermansky-Pudlak syndrome 5
chr6_+_30908747	0.016	ENST00000462446.1 ENST00000304311.2	DPCR1	diffuse panbronchiolitis critical region 1
chr8_-_28747424	0.015	ENST00000523436.1 ENST00000397363.4 ENST00000521777.1 ENST00000520184.1 ENST00000521022.1	INTS9	integrator complex subunit 9
chr20_-_22665932	0.014	ENST00000437696.1	RP11-359G22.2	RP11-359G22.2
chr20_+_54987168	0.014	ENST00000360314.3	CASS4	Cas scaffolding protein family member 4
chr8_+_67624653	0.013	ENST00000521198.2	SGK3	serum/glucocorticoid regulated kinase family, member 3
chr2_-_127977654	0.011	ENST00000409327.1	CYP27C1	cytochrome P450, family 27, subfamily C, polypeptide 1
chr14_-_24977457	0.009	ENST00000250378.3 ENST00000206446.4	CMA1	chymase 1, mast cell
chr1_+_89246647	0.009	ENST00000544045.1	PKN2	protein kinase N2
chr3_-_11610255	0.009	ENST00000424529.2	VGLL4	vestigial like 4 (Drosophila)
chr11_-_18343669	0.008	ENST00000396253.3 ENST00000349215.3 ENST00000438420.2	HPS5	Hermansky-Pudlak syndrome 5
chr22_+_23222886	0.006	ENST00000390319.2	IGLV3-1	immunoglobulin lambda variable 3-1
chr17_-_34417479	0.006	ENST00000225245.5	CCL3	chemokine (C-C motif) ligand 3
chr8_-_96281419	0.006	ENST00000286688.5	C8orf37	chromosome 8 open reading frame 37
chr5_+_131396222	0.006	ENST00000296870.2	IL3	interleukin 3 (colony-stimulating factor, multiple)
chr4_+_88896819	0.005	ENST00000237623.7 ENST00000395080.3 ENST00000508233.1 ENST00000360804.4	SPP1	secreted phosphoprotein 1
chr1_+_159770292	0.004	ENST00000536257.1 ENST00000321935.6	FCRL6	Fc receptor-like 6
chr12_+_15125954	0.003	ENST00000266395.2	PDE6H	phosphodiesterase 6H, cGMP-specific, cone, gamma
chr6_-_34524093	0.002	ENST00000544425.1	SPDEF	SAM pointed domain containing ETS transcription factor
chr8_-_134072593	0.001	ENST00000427060.2	SLA	Src-like-adaptor
chr1_-_184006829	0.001	ENST00000361927.4	COLGALT2	collagen beta(1-O)galactosyltransferase 2
chr6_-_113953705	0.001	ENST00000452675.1	RP11-367G18.1	RP11-367G18.1

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:2000502	T cell extravasation(GO:0072683) negative regulation of natural killer cell chemotaxis(GO:2000502)
0.1	0.7	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0	0.3	GO:0061767	negative regulation of lung blood pressure(GO:0061767)
0.0	0.2	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.0	0.1	GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0	0.2	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0097466	protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	GO:0005595	collagen type XII trimer(GO:0005595)
0.0	0.3	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0004917	interleukin-7 receptor activity(GO:0004917)
0.0	0.3	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.4	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.1	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.7	REACTOME_IL_7_SIGNALING	Genes involved in Interleukin-7 signaling

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