Motif ID: BPTF

Z-value: 0.745


Transcription factors associated with BPTF:

Gene SymbolEntrez IDGene Name
BPTF ENSG00000171634.12 BPTF

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
BPTFhg19_v2_chr17_+_65821636_65821641-0.265.0e-01Click!


Activity profile for motif BPTF.

activity profile for motif BPTF


Sorted Z-values histogram for motif BPTF

Sorted Z-values for motif BPTF



Network of associatons between targets according to the STRING database.



First level regulatory network of BPTF

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_110723194 0.512 ENST00000394635.3
CFI
complement factor I
chr2_+_36923933 0.407 ENST00000497382.1
ENST00000404084.1
ENST00000379241.3
ENST00000401530.1
VIT



vitrin



chr2_+_36923830 0.375 ENST00000379242.3
ENST00000389975.3
VIT

vitrin

chr6_-_13290684 0.365 ENST00000606393.1
RP1-257A7.5
RP1-257A7.5
chr2_-_183291741 0.344 ENST00000351439.5
ENST00000409365.1
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chr2_+_36923901 0.343 ENST00000457137.2
VIT
vitrin
chr6_-_64029879 0.341 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN


lengsin, lens protein with glutamine synthetase domain


chr4_-_110723134 0.334 ENST00000510800.1
ENST00000512148.1
CFI

complement factor I

chr1_-_12677714 0.330 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr3_+_151591422 0.329 ENST00000362032.5
SUCNR1
succinate receptor 1
chr6_-_116866773 0.318 ENST00000368602.3
TRAPPC3L
trafficking protein particle complex 3-like
chr3_+_154741907 0.315 ENST00000492661.1
MME
membrane metallo-endopeptidase
chr12_-_8815404 0.312 ENST00000359478.2
ENST00000396549.2
MFAP5

microfibrillar associated protein 5

chr4_-_110723335 0.307 ENST00000394634.2
CFI
complement factor I
chr3_+_4535155 0.305 ENST00000544951.1
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr15_-_31521567 0.299 ENST00000560812.1
ENST00000559853.1
ENST00000558109.1
RP11-16E12.2


RP11-16E12.2


chr12_-_719573 0.284 ENST00000397265.3
NINJ2
ninjurin 2
chr4_-_186877806 0.276 ENST00000355634.5
SORBS2
sorbin and SH3 domain containing 2
chr4_-_90759440 0.268 ENST00000336904.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr2_-_36779411 0.261 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr12_+_7169887 0.259 ENST00000542978.1
C1S
complement component 1, s subcomponent
chr13_-_20357057 0.252 ENST00000338910.4
PSPC1
paraspeckle component 1
chr12_-_71148413 0.244 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
PTPRR


protein tyrosine phosphatase, receptor type, R


chr19_+_47813110 0.240 ENST00000355085.3
C5AR1
complement component 5a receptor 1
chr12_-_8815215 0.234 ENST00000544889.1
ENST00000543369.1
MFAP5

microfibrillar associated protein 5

chr19_+_15783879 0.231 ENST00000551607.1
CYP4F12
cytochrome P450, family 4, subfamily F, polypeptide 12
chr20_+_23168759 0.231 ENST00000411595.1
RP4-737E23.2
RP4-737E23.2
chr3_+_140981456 0.231 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr12_-_8815477 0.231 ENST00000433590.2
MFAP5
microfibrillar associated protein 5
chr5_+_32788945 0.226 ENST00000326958.1
AC026703.1
AC026703.1
chr7_+_106810165 0.222 ENST00000468401.1
ENST00000497535.1
ENST00000485846.1
HBP1


HMG-box transcription factor 1


chr1_-_24151903 0.221 ENST00000436439.2
ENST00000374490.3
HMGCL

3-hydroxymethyl-3-methylglutaryl-CoA lyase

chr17_+_4855053 0.219 ENST00000518175.1
ENO3
enolase 3 (beta, muscle)
chr12_+_120740119 0.208 ENST00000536460.1
ENST00000202967.4
SIRT4

sirtuin 4

chr1_+_93297582 0.207 ENST00000370321.3
RPL5
ribosomal protein L5
chr4_-_186696561 0.206 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2





sorbin and SH3 domain containing 2





chr2_+_211342400 0.205 ENST00000417946.1
ENST00000518043.1
ENST00000523702.1
CPS1


carbamoyl-phosphate synthase 1, mitochondrial


chr16_+_89628778 0.205 ENST00000472354.1
RPL13
ribosomal protein L13
chr5_+_53751445 0.203 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr9_-_34710066 0.200 ENST00000378792.1
ENST00000259607.2
CCL21

chemokine (C-C motif) ligand 21

chr17_-_41465674 0.198 ENST00000592135.1
ENST00000587874.1
ENST00000588654.1
ENST00000592094.1
LINC00910



long intergenic non-protein coding RNA 910



chr19_-_39322299 0.198 ENST00000601094.1
ENST00000595567.1
ENST00000602115.1
ENST00000601778.1
ENST00000597205.1
ENST00000595470.1
ECH1





enoyl CoA hydratase 1, peroxisomal





chr3_-_93692781 0.197 ENST00000394236.3
PROS1
protein S (alpha)
chr11_+_12308447 0.196 ENST00000256186.2
MICALCL
MICAL C-terminal like
chr18_-_48351743 0.194 ENST00000588444.1
ENST00000256425.2
ENST00000428869.2
MRO


maestro


chr4_-_186696425 0.194 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2


sorbin and SH3 domain containing 2


chr11_+_107650219 0.188 ENST00000398067.1
AP001024.1
Uncharacterized protein
chr6_-_37467628 0.186 ENST00000373408.3
CCDC167
coiled-coil domain containing 167
chr12_-_71148357 0.186 ENST00000378778.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr12_-_8815299 0.185 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr16_-_46782221 0.185 ENST00000394809.4
MYLK3
myosin light chain kinase 3
chr2_+_85661918 0.184 ENST00000340326.2
SH2D6
SH2 domain containing 6
chr9_+_67977438 0.183 ENST00000456982.1
RP11-195B21.3
Protein LOC644249
chr4_+_157997273 0.183 ENST00000541722.1
ENST00000512619.1
GLRB

glycine receptor, beta

chr19_-_13030071 0.180 ENST00000293695.7
SYCE2
synaptonemal complex central element protein 2
chr1_+_93297622 0.180 ENST00000315741.5
RPL5
ribosomal protein L5
chr15_+_55611128 0.180 ENST00000164305.5
ENST00000539642.1
PIGB

phosphatidylinositol glycan anchor biosynthesis, class B

chr12_-_112847354 0.179 ENST00000550566.2
ENST00000553213.2
ENST00000424576.2
ENST00000202773.9
RPL6



ribosomal protein L6



chr15_-_44069741 0.177 ENST00000319359.3
ELL3
elongation factor RNA polymerase II-like 3
chr19_-_57656570 0.175 ENST00000269834.1
ZIM3
zinc finger, imprinted 3
chr3_+_154801678 0.175 ENST00000462837.1
MME
membrane metallo-endopeptidase
chr5_-_24645078 0.175 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr2_-_211341411 0.175 ENST00000233714.4
ENST00000443314.1
ENST00000441020.3
ENST00000450366.2
ENST00000431941.2
LANCL1




LanC lantibiotic synthetase component C-like 1 (bacterial)




chr17_-_7167279 0.172 ENST00000571932.2
CLDN7
claudin 7
chr1_+_44514040 0.172 ENST00000431800.1
ENST00000437643.1
RP5-1198O20.4

RP5-1198O20.4

chrX_-_134953994 0.171 ENST00000420087.2
ENST00000463085.2
ENST00000370724.3
CT45A4
CT45A5

cancer/testis antigen family 45, member A4
cancer/testis antigen family 45, member A5

chr2_+_46844290 0.171 ENST00000238892.3
CRIPT
cysteine-rich PDZ-binding protein
chr19_+_11708229 0.170 ENST00000361113.5
ZNF627
zinc finger protein 627
chr7_-_138348969 0.170 ENST00000436657.1
SVOPL
SVOP-like
chr1_-_117021430 0.169 ENST00000423907.1
ENST00000434879.1
ENST00000443219.1
RP4-655J12.4


RP4-655J12.4


chr3_+_52017454 0.167 ENST00000476854.1
ENST00000476351.1
ENST00000494103.1
ENST00000404366.2
ENST00000469863.1
ACY1




aminoacylase 1




chr6_-_134639235 0.167 ENST00000533224.1
SGK1
serum/glucocorticoid regulated kinase 1
chr17_-_7166500 0.167 ENST00000575313.1
ENST00000397317.4
CLDN7

claudin 7

chr17_+_27046988 0.167 ENST00000496182.1
RPL23A
ribosomal protein L23a
chr2_+_30370382 0.167 ENST00000402708.1
YPEL5
yippee-like 5 (Drosophila)
chr4_+_78079450 0.164 ENST00000395640.1
ENST00000512918.1
CCNG2

cyclin G2

chr1_-_170043709 0.164 ENST00000367767.1
ENST00000361580.2
ENST00000538366.1
KIFAP3


kinesin-associated protein 3


chr14_-_47351391 0.163 ENST00000399222.3
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr12_+_47610315 0.162 ENST00000548348.1
ENST00000549500.1
PCED1B

PC-esterase domain containing 1B

chr9_+_137987825 0.161 ENST00000545657.1
OLFM1
olfactomedin 1
chr14_+_70918874 0.160 ENST00000603540.1
ADAM21
ADAM metallopeptidase domain 21
chr18_-_33702078 0.159 ENST00000586829.1
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr12_-_108991778 0.159 ENST00000549447.1
TMEM119
transmembrane protein 119
chr4_+_78079570 0.159 ENST00000509972.1
CCNG2
cyclin G2
chr15_+_55611401 0.158 ENST00000566999.1
PIGB
phosphatidylinositol glycan anchor biosynthesis, class B
chr19_-_45996465 0.158 ENST00000430715.2
RTN2
reticulon 2
chr10_-_69597915 0.157 ENST00000225171.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr15_+_41624892 0.154 ENST00000260359.6
ENST00000450318.1
ENST00000450592.2
ENST00000559596.1
ENST00000414849.2
ENST00000560747.1
ENST00000560177.1
NUSAP1






nucleolar and spindle associated protein 1






chr3_+_4535025 0.153 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
ITPR1




inositol 1,4,5-trisphosphate receptor, type 1




chr5_+_53686658 0.153 ENST00000512618.1
LINC01033
long intergenic non-protein coding RNA 1033
chr1_+_234509413 0.153 ENST00000366613.1
ENST00000366612.1
COA6

cytochrome c oxidase assembly factor 6 homolog (S. cerevisiae)

chr1_+_197237352 0.153 ENST00000538660.1
ENST00000367400.3
ENST00000367399.2
CRB1


crumbs homolog 1 (Drosophila)


chr4_-_186696515 0.153 ENST00000456596.1
ENST00000414724.1
SORBS2

sorbin and SH3 domain containing 2

chr15_-_55657428 0.152 ENST00000568543.1
CCPG1
cell cycle progression 1
chr11_+_63998006 0.152 ENST00000355040.4
DNAJC4
DnaJ (Hsp40) homolog, subfamily C, member 4
chr5_+_32710736 0.151 ENST00000415685.2
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr12_-_110888103 0.150 ENST00000426440.1
ENST00000228825.7
ARPC3

actin related protein 2/3 complex, subunit 3, 21kDa

chr1_-_6260896 0.150 ENST00000497965.1
RPL22
ribosomal protein L22
chr3_-_192445289 0.149 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
FGF12



fibroblast growth factor 12



chr6_+_62284008 0.148 ENST00000544932.1
MTRNR2L9
MT-RNR2-like 9 (pseudogene)
chr14_+_74318611 0.148 ENST00000555976.1
ENST00000267568.4
PTGR2

prostaglandin reductase 2

chr10_-_102790852 0.148 ENST00000470414.1
ENST00000370215.3
PDZD7

PDZ domain containing 7

chr12_+_51318513 0.148 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr4_+_78078304 0.146 ENST00000316355.5
ENST00000354403.5
ENST00000502280.1
CCNG2


cyclin G2


chr1_-_235098935 0.146 ENST00000423175.1
RP11-443B7.1
RP11-443B7.1
chr12_+_16064106 0.145 ENST00000428559.2
DERA
deoxyribose-phosphate aldolase (putative)
chr17_+_27047244 0.144 ENST00000394938.4
ENST00000394935.3
ENST00000355731.4
RPL23A


ribosomal protein L23a


chr16_+_77756399 0.144 ENST00000564085.1
ENST00000268533.5
ENST00000568787.1
ENST00000437314.3
ENST00000563839.1
NUDT7




nudix (nucleoside diphosphate linked moiety X)-type motif 7




chr11_+_107992243 0.142 ENST00000265838.4
ENST00000299355.6
ACAT1

acetyl-CoA acetyltransferase 1

chr17_-_10633291 0.142 ENST00000578345.1
ENST00000455996.2
TMEM220

transmembrane protein 220

chr10_-_25241499 0.141 ENST00000376378.1
ENST00000376376.3
ENST00000320152.6
PRTFDC1


phosphoribosyl transferase domain containing 1


chr12_-_89918982 0.141 ENST00000549504.1
POC1B
POC1 centriolar protein B
chr12_+_51317788 0.141 ENST00000550502.1
METTL7A
methyltransferase like 7A
chr5_-_10249990 0.141 ENST00000511437.1
ENST00000280330.8
ENST00000510047.1
FAM173B


family with sequence similarity 173, member B


chr2_+_233243233 0.140 ENST00000392027.2
ALPP
alkaline phosphatase, placental
chr19_+_54135310 0.140 ENST00000376650.1
DPRX
divergent-paired related homeobox
chr13_+_28519343 0.139 ENST00000381026.3
ATP5EP2
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2
chr4_+_170581213 0.139 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr11_-_88070920 0.138 ENST00000524463.1
ENST00000227266.5
CTSC

cathepsin C

chr20_+_55099542 0.138 ENST00000371328.3
FAM209A
family with sequence similarity 209, member A
chr10_-_69597828 0.137 ENST00000339758.7
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr5_+_139027877 0.136 ENST00000302517.3
CXXC5
CXXC finger protein 5
chr7_-_38305279 0.136 ENST00000443402.2
TRGC1
T cell receptor gamma constant 1
chr21_+_39493560 0.136 ENST00000400477.3
ENST00000357704.4
DSCR8

Down syndrome critical region gene 8

chr8_+_29952914 0.136 ENST00000321250.8
ENST00000518001.1
ENST00000520682.1
ENST00000442880.2
ENST00000523116.1
LEPROTL1




leptin receptor overlapping transcript-like 1




chr1_-_220263096 0.136 ENST00000463953.1
ENST00000354807.3
ENST00000414869.2
ENST00000498237.2
ENST00000498791.2
ENST00000544404.1
ENST00000480959.2
ENST00000322067.7
BPNT1







3'(2'), 5'-bisphosphate nucleotidase 1







chr3_-_98235962 0.135 ENST00000513873.1
CLDND1
claudin domain containing 1
chr5_+_159848854 0.135 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
PTTG1


pituitary tumor-transforming 1


chr2_-_152118276 0.135 ENST00000409092.1
RBM43
RNA binding motif protein 43
chrX_-_57147902 0.135 ENST00000275988.5
ENST00000434397.1
ENST00000333933.3
ENST00000374912.5
SPIN2B



spindlin family, member 2B



chr12_-_8088871 0.134 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr4_-_90758227 0.134 ENST00000506691.1
ENST00000394986.1
ENST00000506244.1
ENST00000394989.2
ENST00000394991.3
SNCA




synuclein, alpha (non A4 component of amyloid precursor)




chr18_+_21572737 0.134 ENST00000304621.6
TTC39C
tetratricopeptide repeat domain 39C
chr8_+_128427857 0.133 ENST00000391675.1
POU5F1B
POU class 5 homeobox 1B
chr1_+_32379174 0.133 ENST00000391369.1
AL136115.1
HCG2032337; PRO1848; Uncharacterized protein
chr14_-_55658323 0.133 ENST00000554067.1
ENST00000247191.2
DLGAP5

discs, large (Drosophila) homolog-associated protein 5

chr7_+_101460882 0.133 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
CUX1




cut-like homeobox 1




chr11_-_111794446 0.133 ENST00000527950.1
CRYAB
crystallin, alpha B
chr19_-_29704448 0.132 ENST00000304863.4
UQCRFS1
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr12_-_54689532 0.132 ENST00000540264.2
ENST00000312156.4
NFE2

nuclear factor, erythroid 2

chr19_-_45457264 0.132 ENST00000591646.1
CTB-129P6.11
Uncharacterized protein
chr4_+_41614909 0.132 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1


LIM and calponin homology domains 1


chr9_+_74764340 0.132 ENST00000376986.1
ENST00000358399.3
GDA

guanine deaminase

chr19_+_42055879 0.131 ENST00000407170.2
ENST00000601116.1
ENST00000595395.1
CEACAM21
AC006129.2

carcinoembryonic antigen-related cell adhesion molecule 21
AC006129.2

chr3_+_154801312 0.131 ENST00000497890.1
MME
membrane metallo-endopeptidase
chr19_-_6690723 0.130 ENST00000601008.1
C3
complement component 3
chr4_+_57845024 0.129 ENST00000431623.2
ENST00000441246.2
POLR2B

polymerase (RNA) II (DNA directed) polypeptide B, 140kDa

chr8_+_128426535 0.129 ENST00000465342.2
POU5F1B
POU class 5 homeobox 1B
chr7_-_95064264 0.129 ENST00000536183.1
ENST00000433091.2
ENST00000222572.3
PON2


paraoxonase 2


chr10_-_16563870 0.128 ENST00000298943.3
C1QL3
complement component 1, q subcomponent-like 3
chr17_+_62461569 0.128 ENST00000603557.1
ENST00000605096.1
MILR1

mast cell immunoglobulin-like receptor 1

chr21_+_38593701 0.127 ENST00000440629.1
AP001432.14
AP001432.14
chr3_-_57260377 0.127 ENST00000495160.2
HESX1
HESX homeobox 1
chr1_+_241695424 0.127 ENST00000366558.3
ENST00000366559.4
KMO

kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)

chr14_+_61449197 0.127 ENST00000533744.2
SLC38A6
solute carrier family 38, member 6
chr6_+_89790490 0.126 ENST00000336032.3
PNRC1
proline-rich nuclear receptor coactivator 1
chrX_-_80457385 0.126 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
HMGN5


high mobility group nucleosome binding domain 5


chr10_-_13350447 0.126 ENST00000429930.1
AL138764.1
Uncharacterized protein
chr4_-_186570679 0.126 ENST00000451974.1
SORBS2
sorbin and SH3 domain containing 2
chr3_-_4508925 0.125 ENST00000534863.1
ENST00000383843.5
ENST00000458465.2
ENST00000405420.2
ENST00000272902.5
SUMF1




sulfatase modifying factor 1




chr8_-_123706338 0.125 ENST00000521608.1
RP11-973F15.1
long intergenic non-protein coding RNA 1151
chr1_+_241695670 0.124 ENST00000366557.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr3_-_157217328 0.124 ENST00000392832.2
ENST00000543418.1
VEPH1

ventricular zone expressed PH domain-containing 1

chr17_-_6554747 0.123 ENST00000574128.1
MED31
mediator complex subunit 31
chr1_-_165667545 0.122 ENST00000538148.1
ALDH9A1
aldehyde dehydrogenase 9 family, member A1
chr3_-_52569023 0.121 ENST00000307076.4
NT5DC2
5'-nucleotidase domain containing 2
chr17_-_74547256 0.121 ENST00000589145.1
CYGB
cytoglobin
chr6_-_133119649 0.121 ENST00000367918.1
SLC18B1
solute carrier family 18, subfamily B, member 1
chr2_+_196440692 0.121 ENST00000458054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr17_+_74261277 0.121 ENST00000327490.6
UBALD2
UBA-like domain containing 2
chrX_+_24483338 0.120 ENST00000379162.4
ENST00000441463.2
PDK3

pyruvate dehydrogenase kinase, isozyme 3

chrX_-_153775047 0.119 ENST00000433845.1
ENST00000439227.1
G6PD

glucose-6-phosphate dehydrogenase

chr6_-_133119668 0.119 ENST00000275227.4
ENST00000538764.1
SLC18B1

solute carrier family 18, subfamily B, member 1

chr2_-_211342292 0.119 ENST00000448951.1
LANCL1
LanC lantibiotic synthetase component C-like 1 (bacterial)
chr11_+_63997750 0.118 ENST00000321685.3
DNAJC4
DnaJ (Hsp40) homolog, subfamily C, member 4
chrX_-_138724677 0.118 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF2


MCF.2 cell line derived transforming sequence


chr4_-_89744365 0.117 ENST00000513837.1
ENST00000503556.1
FAM13A

family with sequence similarity 13, member A

chr17_-_5321549 0.117 ENST00000572809.1
NUP88
nucleoporin 88kDa
chr15_-_96590126 0.117 ENST00000561051.1
RP11-4G2.1
RP11-4G2.1
chr14_+_74035763 0.117 ENST00000238651.5
ACOT2
acyl-CoA thioesterase 2
chr3_+_10157276 0.117 ENST00000530758.1
ENST00000256463.6
BRK1

BRICK1, SCAR/WAVE actin-nucleating complex subunit

chr4_+_25162253 0.116 ENST00000512921.1
PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr9_+_107526443 0.116 ENST00000374762.3
NIPSNAP3B
nipsnap homolog 3B (C. elegans)
chr12_-_25150373 0.116 ENST00000549828.1
C12orf77
chromosome 12 open reading frame 77
chr6_-_99842041 0.116 ENST00000254759.3
ENST00000369242.1
COQ3

coenzyme Q3 methyltransferase

chr1_-_1624083 0.116 ENST00000378662.1
ENST00000234800.6
SLC35E2B

solute carrier family 35, member E2B

chr20_+_43343476 0.115 ENST00000372868.2
WISP2
WNT1 inducible signaling pathway protein 2
chr14_-_88282595 0.115 ENST00000554519.1
RP11-1152H15.1
RP11-1152H15.1
chr19_+_49838653 0.115 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37





CD37 molecule





chr11_+_62652649 0.115 ENST00000539507.1
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chrX_-_19533379 0.115 ENST00000338883.4
MAP3K15
mitogen-activated protein kinase kinase kinase 15
chr11_-_88070896 0.115 ENST00000529974.1
ENST00000527018.1
CTSC

cathepsin C

chr12_-_25150409 0.115 ENST00000549262.1
C12orf77
chromosome 12 open reading frame 77
chr4_-_186697044 0.114 ENST00000437304.2
SORBS2
sorbin and SH3 domain containing 2
chr16_-_18801643 0.114 ENST00000322989.4
ENST00000563390.1
RPS15A

ribosomal protein S15a

chr18_+_32290218 0.114 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
DTNA


dystrobrevin, alpha


chr1_+_229440129 0.113 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr17_+_58018269 0.113 ENST00000591035.1
RP11-178C3.1
Uncharacterized protein
chr17_-_76628125 0.113 ENST00000586185.1
ENST00000591384.1
CTD-2357A8.3

CTD-2357A8.3

chr1_-_15850676 0.112 ENST00000440484.1
ENST00000333868.5
CASP9

caspase 9, apoptosis-related cysteine peptidase


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.4 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.4 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.1 0.3 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
0.1 0.2 GO:0003095 pressure natriuresis(GO:0003095)
0.1 0.2 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.1 0.5 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.2 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.1 0.2 GO:0070408 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.1 0.2 GO:0006147 guanine catabolic process(GO:0006147)
0.1 0.2 GO:2000547 mesangial cell-matrix adhesion(GO:0035759) regulation of dendritic cell dendrite assembly(GO:2000547)
0.1 0.4 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.2 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.1 0.3 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.1 0.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 0.6 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.2 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.3 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 0.3 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.2 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.4 GO:0000075 cell cycle checkpoint(GO:0000075)
0.0 0.1 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.0 0.3 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.1 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.0 0.4 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0 0.1 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.2 GO:0061056 sclerotome development(GO:0061056)
0.0 0.1 GO:1990641 response to iron ion starvation(GO:1990641)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0006550 isoleucine catabolic process(GO:0006550)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.3 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.2 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 1.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0046203 spermidine catabolic process(GO:0046203)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.0 0.2 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.2 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.2 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.1 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.1 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.0 0.1 GO:1903860 negative regulation of dendrite extension(GO:1903860)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.0 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.2 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 0.1 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.1 GO:0006844 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.0 0.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.5 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.1 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.0 0.1 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.2 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 0.1 GO:0050993 dimethylallyl diphosphate biosynthetic process(GO:0050992) dimethylallyl diphosphate metabolic process(GO:0050993)
0.0 1.7 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.8 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:0060356 leucine import(GO:0060356)
0.0 0.3 GO:1903012 positive regulation of bone development(GO:1903012)
0.0 0.0 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:0051167 glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159)
0.0 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.0 GO:0010446 response to alkaline pH(GO:0010446)
0.0 0.0 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.1 GO:0039506 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.0 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.1 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.0 0.2 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.0 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.1 GO:0019427 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.0 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0002415 immune response in mucosal-associated lymphoid tissue(GO:0002386) immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.0 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.0 0.2 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.0 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.0 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.1 GO:0070541 response to platinum ion(GO:0070541)
0.0 0.0 GO:0072553 terminal button organization(GO:0072553)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0061740 protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.1 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.0 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.0 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:0015755 fructose transport(GO:0015755)
0.0 0.2 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.1 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.0 0.5 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0 0.5 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.0 GO:0044691 tooth eruption(GO:0044691)
0.0 0.1 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.1 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.0 GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.0 GO:0003357 noradrenergic neuron differentiation(GO:0003357) N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.0 GO:1901536 negative regulation of DNA demethylation(GO:1901536)
0.0 0.1 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 0.0 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.0 0.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.1 GO:1900194 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.0 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.1 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.0 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.1 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.1 0.2 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 1.1 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.0 1.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0097637 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.0 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.3 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.1 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.0 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.0 GO:0072563 endothelial microparticle(GO:0072563)
0.0 0.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.0 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.0 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.2 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.1 GO:0044423 virion(GO:0019012) virion part(GO:0044423)
0.0 0.0 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.3 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.1 0.5 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.4 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.2 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.1 0.2 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.1 0.2 GO:0008892 guanine deaminase activity(GO:0008892)
0.1 0.3 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.1 0.2 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 0.6 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.2 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.2 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.2 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.2 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.3 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.0 0.3 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.3 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.2 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.1 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.0 0.1 GO:0051908 double-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0051908)
0.0 0.1 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.3 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.0 GO:0032554 deoxyribonucleotide binding(GO:0032552) purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.2 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.2 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 1.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.1 GO:0019144 ADP-sugar diphosphatase activity(GO:0019144)
0.0 0.1 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.1 GO:0035326 enhancer binding(GO:0035326)
0.0 0.1 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.1 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.0 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226) acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.1 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0008169 C-methyltransferase activity(GO:0008169)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0004325 ferrochelatase activity(GO:0004325)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.0 0.3 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.0 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.5 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.5 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.0 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.0 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.0 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.0 GO:0016296 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.0 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.1 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.0 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 0.0 GO:0071633 dihydroceramidase activity(GO:0071633)
0.0 0.0 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.0 0.0 GO:0070698 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617) type I activin receptor binding(GO:0070698)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.0 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.4 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.4 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 2.2 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.4 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis