Motif ID: BCL6B

Z-value: 0.296


Transcription factors associated with BCL6B:

Gene SymbolEntrez IDGene Name
BCL6B ENSG00000161940.6 BCL6B

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
BCL6Bhg19_v2_chr17_+_6926381_69264210.571.1e-01Click!


Activity profile for motif BCL6B.

activity profile for motif BCL6B


Sorted Z-values histogram for motif BCL6B

Sorted Z-values for motif BCL6B



Network of associatons between targets according to the STRING database.



First level regulatory network of BCL6B

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_76957214 0.539 ENST00000306621.3
 CXCL11
chemokine (C-X-C motif) ligand 11
chr12_+_104324112 0.237 ENST00000299767.5
 HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr4_+_89378261 0.212 ENST00000264350.3
 HERC5
HECT and RLD domain containing E3 ubiquitin protein ligase 5
chr6_-_28973037 0.110 ENST00000377179.3
 ZNF311
zinc finger protein 311
chr10_+_81065975 0.108 ENST00000446377.2
 ZMIZ1
zinc finger, MIZ-type containing 1
chr17_+_77021702 0.105 ENST00000392445.2
ENST00000354124.3
 C1QTNF1

C1q and tumor necrosis factor related protein 1

chr17_-_9694614 0.103 ENST00000330255.5
ENST00000571134.1
 DHRS7C

dehydrogenase/reductase (SDR family) member 7C

chr12_-_123187890 0.102 ENST00000328880.5
 HCAR2
hydroxycarboxylic acid receptor 2
chr12_-_48276710 0.102 ENST00000550314.1
 VDR
vitamin D (1,25- dihydroxyvitamin D3) receptor
chr12_-_123201337 0.100 ENST00000528880.2
 HCAR3
hydroxycarboxylic acid receptor 3
chr11_+_58912240 0.090 ENST00000527629.1
ENST00000361723.3
ENST00000531408.1
 FAM111A


family with sequence similarity 111, member A


chr1_-_8000872 0.089 ENST00000377507.3
 TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr8_-_81787006 0.084 ENST00000327835.3
 ZNF704
zinc finger protein 704
chr13_-_30160925 0.083 ENST00000450494.1
 SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr6_-_28304152 0.078 ENST00000435857.1
 ZSCAN31
zinc finger and SCAN domain containing 31
chr3_+_158787041 0.077 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
 IQCJ-SCHIP1


IQCJ-SCHIP1 readthrough


chr6_-_28303901 0.076 ENST00000439158.1
ENST00000446474.1
ENST00000414431.1
ENST00000344279.6
ENST00000453745.1
 ZSCAN31




zinc finger and SCAN domain containing 31




chr7_+_28452130 0.072 ENST00000357727.2
 CREB5
cAMP responsive element binding protein 5
chr14_+_39944025 0.070 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
 RP11-111A21.1


RP11-111A21.1


chr3_-_112329110 0.070 ENST00000479368.1
 CCDC80
coiled-coil domain containing 80
chr1_-_150669604 0.069 ENST00000427665.1
ENST00000540514.1
 GOLPH3L

golgi phosphoprotein 3-like

chrX_-_54209640 0.063 ENST00000375180.2
ENST00000328235.4
ENST00000477084.1
 FAM120C


family with sequence similarity 120C


chr17_-_48474828 0.062 ENST00000576448.1
ENST00000225972.7
 LRRC59

leucine rich repeat containing 59

chr3_+_156799587 0.060 ENST00000469196.1
 RP11-6F2.5
RP11-6F2.5
chr12_+_93964746 0.059 ENST00000536696.2
 SOCS2
suppressor of cytokine signaling 2
chr11_+_120081475 0.059 ENST00000328965.4
 OAF
OAF homolog (Drosophila)
chr19_+_11200038 0.058 ENST00000558518.1
ENST00000557933.1
ENST00000455727.2
ENST00000535915.1
ENST00000545707.1
ENST00000558013.1
 LDLR





low density lipoprotein receptor





chr11_+_61159832 0.054 ENST00000334888.5
ENST00000398979.3
 TMEM216

transmembrane protein 216

chr12_-_11002063 0.054 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
 PRR4


proline rich 4 (lacrimal)


chr19_-_13227534 0.052 ENST00000588229.1
ENST00000357720.4
 TRMT1

tRNA methyltransferase 1 homolog (S. cerevisiae)

chr18_-_52989525 0.051 ENST00000457482.3
 TCF4
transcription factor 4
chr7_+_2636522 0.051 ENST00000423196.1
 IQCE
IQ motif containing E
chr18_+_72167096 0.050 ENST00000324301.8
 CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr14_+_61449076 0.049 ENST00000526105.1
 SLC38A6
solute carrier family 38, member 6
chr12_+_79371565 0.048 ENST00000551304.1
 SYT1
synaptotagmin I
chr19_-_13227514 0.047 ENST00000587487.1
ENST00000592814.1
 TRMT1

tRNA methyltransferase 1 homolog (S. cerevisiae)

chr19_-_13227463 0.046 ENST00000437766.1
ENST00000221504.8
 TRMT1

tRNA methyltransferase 1 homolog (S. cerevisiae)

chr16_-_75498308 0.045 ENST00000569540.1
 TMEM170A
transmembrane protein 170A
chr22_-_30642728 0.043 ENST00000403987.3
 LIF
leukemia inhibitory factor
chr16_-_18441131 0.043 ENST00000339303.5
 NPIPA8
nuclear pore complex interacting protein family, member A8
chr6_+_42584847 0.042 ENST00000372883.3
 UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr3_-_23958402 0.040 ENST00000415901.2
ENST00000416026.2
ENST00000412028.1
ENST00000388759.3
ENST00000437230.1
 NKIRAS1




NFKB inhibitor interacting Ras-like 1




chr11_+_74303612 0.039 ENST00000527458.1
ENST00000532497.1
ENST00000530511.1
 POLD3


polymerase (DNA-directed), delta 3, accessory subunit


chr12_+_31812121 0.039 ENST00000395763.3
 METTL20
methyltransferase like 20
chr1_-_54405773 0.039 ENST00000371376.1
 HSPB11
heat shock protein family B (small), member 11
chr6_+_125540951 0.039 ENST00000524679.1
 TPD52L1
tumor protein D52-like 1
chr3_+_102153859 0.037 ENST00000306176.1
ENST00000466937.1
 ZPLD1

zona pellucida-like domain containing 1

chr3_+_44690211 0.037 ENST00000396056.2
ENST00000432115.2
ENST00000415571.2
ENST00000399560.2
ENST00000296092.3
ENST00000542250.1
ENST00000453164.1
 ZNF35






zinc finger protein 35






chr6_-_32083106 0.037 ENST00000442721.1
 TNXB
tenascin XB
chr14_-_100046444 0.036 ENST00000554996.1
 CCDC85C
coiled-coil domain containing 85C
chr19_+_39786962 0.036 ENST00000333625.2
 IFNL1
interferon, lambda 1
chr9_+_97766409 0.036 ENST00000425634.2
 C9orf3
chromosome 9 open reading frame 3
chr14_-_80678512 0.035 ENST00000553968.1
 DIO2
deiodinase, iodothyronine, type II
chr1_-_108735440 0.035 ENST00000370041.4
 SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr2_+_87754989 0.033 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
 LINC00152



long intergenic non-protein coding RNA 152



chr12_-_49581152 0.032 ENST00000550811.1
 TUBA1A
tubulin, alpha 1a
chr7_+_872107 0.031 ENST00000405266.1
ENST00000401592.1
ENST00000403868.1
ENST00000425407.2
 SUN1



Sad1 and UNC84 domain containing 1



chr19_-_4831701 0.031 ENST00000248244.5
 TICAM1
toll-like receptor adaptor molecule 1
chr3_-_23958506 0.029 ENST00000425478.2
 NKIRAS1
NFKB inhibitor interacting Ras-like 1
chr11_+_58874701 0.029 ENST00000529618.1
ENST00000534403.1
ENST00000343597.3
 FAM111B


family with sequence similarity 111, member B


chr1_-_150669500 0.029 ENST00000271732.3
 GOLPH3L
golgi phosphoprotein 3-like
chr14_-_21567009 0.028 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
 ZNF219



zinc finger protein 219



chr19_+_10197463 0.028 ENST00000590378.1
ENST00000397881.3
 C19orf66

chromosome 19 open reading frame 66

chr19_+_44037546 0.027 ENST00000601282.1
 ZNF575
zinc finger protein 575
chr12_-_49245916 0.027 ENST00000552512.1
ENST00000551468.1
 DDX23

DEAD (Asp-Glu-Ala-Asp) box polypeptide 23

chr22_-_50699701 0.026 ENST00000395780.1
 MAPK12
mitogen-activated protein kinase 12
chr9_+_97766469 0.025 ENST00000433691.2
 C9orf3
chromosome 9 open reading frame 3
chr1_+_221051699 0.025 ENST00000366903.6
 HLX
H2.0-like homeobox
chr6_+_7541845 0.025 ENST00000418664.2
 DSP
desmoplakin
chr12_-_12674032 0.025 ENST00000298573.4
 DUSP16
dual specificity phosphatase 16
chr18_+_66382428 0.025 ENST00000578970.1
ENST00000582371.1
ENST00000584775.1
 CCDC102B


coiled-coil domain containing 102B


chr2_+_239756671 0.024 ENST00000448943.2
 TWIST2
twist family bHLH transcription factor 2
chr17_-_42907564 0.024 ENST00000592524.1
 GJC1
gap junction protein, gamma 1, 45kDa
chr19_+_44037334 0.024 ENST00000314228.5
 ZNF575
zinc finger protein 575
chr20_+_43990576 0.024 ENST00000372727.1
ENST00000414310.1
 SYS1

SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)

chr5_-_58295712 0.023 ENST00000317118.8
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr21_+_17909594 0.023 ENST00000441820.1
ENST00000602280.1
 LINC00478

long intergenic non-protein coding RNA 478

chr6_+_31588478 0.023 ENST00000376007.4
ENST00000376033.2
 PRRC2A

proline-rich coiled-coil 2A

chr13_-_33112823 0.023 ENST00000504114.1
 N4BP2L2
NEDD4 binding protein 2-like 2
chr5_-_145214848 0.022 ENST00000505416.1
ENST00000334744.4
ENST00000358004.2
ENST00000511435.1
 PRELID2



PRELI domain containing 2



chr6_+_7541808 0.021 ENST00000379802.3
 DSP
desmoplakin
chr22_-_31503490 0.020 ENST00000400299.2
 SELM
Selenoprotein M
chr17_+_38497640 0.020 ENST00000394086.3
 RARA
retinoic acid receptor, alpha
chr19_-_47616992 0.019 ENST00000253048.5
 ZC3H4
zinc finger CCCH-type containing 4
chr3_-_69101413 0.019 ENST00000398559.2
 TMF1
TATA element modulatory factor 1
chr13_-_28194541 0.019 ENST00000316334.3
 LNX2
ligand of numb-protein X 2
chr4_+_95972822 0.019 ENST00000509540.1
ENST00000440890.2
 BMPR1B

bone morphogenetic protein receptor, type IB

chr3_-_123603137 0.018 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
 MYLK



myosin light chain kinase



chr3_+_177534653 0.018 ENST00000436078.1
 RP11-91K9.1
RP11-91K9.1
chr5_+_72251857 0.017 ENST00000507345.2
ENST00000512348.1
ENST00000287761.6
 FCHO2


FCH domain only 2


chrX_+_153775821 0.017 ENST00000263518.6
ENST00000470142.1
ENST00000393549.2
ENST00000455588.2
ENST00000369602.3
 IKBKG




inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma




chr3_-_69101461 0.017 ENST00000543976.1
 TMF1
TATA element modulatory factor 1
chr16_+_14396121 0.016 ENST00000570945.1
 RP11-65J21.3
RP11-65J21.3
chr14_-_69262789 0.016 ENST00000557022.1
 ZFP36L1
ZFP36 ring finger protein-like 1
chr1_-_74663825 0.016 ENST00000370911.3
ENST00000370909.2
ENST00000354431.4
 LRRIQ3


leucine-rich repeats and IQ motif containing 3


chrX_+_153775869 0.015 ENST00000424839.1
 IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr2_-_157186630 0.015 ENST00000406048.2
 NR4A2
nuclear receptor subfamily 4, group A, member 2
chr9_+_88556036 0.015 ENST00000361671.5
ENST00000416045.1
 NAA35

N(alpha)-acetyltransferase 35, NatC auxiliary subunit

chr5_-_38845812 0.015 ENST00000513480.1
ENST00000512519.1
 CTD-2127H9.1

CTD-2127H9.1

chr8_-_102216925 0.014 ENST00000517844.1
 ZNF706
zinc finger protein 706
chr4_+_86699834 0.014 ENST00000395183.2
 ARHGAP24
Rho GTPase activating protein 24
chr13_-_41345277 0.013 ENST00000323563.6
 MRPS31
mitochondrial ribosomal protein S31
chr11_-_104480019 0.013 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
 RP11-886D15.1


RP11-886D15.1


chr13_+_44596471 0.013 ENST00000592085.1
ENST00000591799.1
 LINC00284

long intergenic non-protein coding RNA 284

chr16_+_58283814 0.012 ENST00000443128.2
ENST00000219299.4
 CCDC113

coiled-coil domain containing 113

chr3_-_123512688 0.012 ENST00000475616.1
 MYLK
myosin light chain kinase
chr19_+_45147098 0.012 ENST00000425690.3
ENST00000344956.4
ENST00000403059.4
 PVR


poliovirus receptor


chr5_+_127039075 0.012 ENST00000514853.2
 CTC-228N24.1
CTC-228N24.1
chr1_+_209878182 0.011 ENST00000367027.3
 HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr21_+_44394742 0.010 ENST00000432907.2
 PKNOX1
PBX/knotted 1 homeobox 1
chr13_-_44980021 0.010 ENST00000432701.2
ENST00000607312.1
 LINC01071

long intergenic non-protein coding RNA 1071

chr4_+_86396265 0.010 ENST00000395184.1
 ARHGAP24
Rho GTPase activating protein 24
chr2_-_216257849 0.009 ENST00000456923.1
 FN1
fibronectin 1
chr18_-_66382289 0.009 ENST00000443099.2
ENST00000562706.1
ENST00000544714.2
 TMX3


thioredoxin-related transmembrane protein 3


chr1_+_84609944 0.009 ENST00000370685.3
 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr15_+_65843130 0.009 ENST00000569894.1
 PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr2_+_87754887 0.009 ENST00000409054.1
ENST00000331944.6
ENST00000409139.1
 LINC00152


long intergenic non-protein coding RNA 152


chr18_-_46895066 0.009 ENST00000583225.1
ENST00000584983.1
ENST00000583280.1
ENST00000581738.1
 DYM



dymeclin



chr2_-_69098566 0.009 ENST00000295379.1
 BMP10
bone morphogenetic protein 10
chr5_+_140480083 0.008 ENST00000231130.2
 PCDHB3
protocadherin beta 3
chr5_+_75904918 0.008 ENST00000514001.1
ENST00000396234.3
ENST00000509074.1
 IQGAP2


IQ motif containing GTPase activating protein 2


chr5_+_72251793 0.008 ENST00000430046.2
ENST00000341845.6
 FCHO2

FCH domain only 2

chr5_-_145214893 0.007 ENST00000394450.2
 PRELID2
PRELI domain containing 2
chr3_-_152058779 0.007 ENST00000408960.3
 TMEM14E
transmembrane protein 14E
chr5_+_75904950 0.007 ENST00000502745.1
 IQGAP2
IQ motif containing GTPase activating protein 2
chr11_+_107643129 0.007 ENST00000447610.1
 AP001024.2
Uncharacterized protein
chr7_-_29152509 0.007 ENST00000448959.1
 CPVL
carboxypeptidase, vitellogenic-like
chr14_+_21566980 0.006 ENST00000418511.2
ENST00000554329.2
 TMEM253

transmembrane protein 253

chr20_-_4229721 0.006 ENST00000379453.4
 ADRA1D
adrenoceptor alpha 1D
chrX_+_135570046 0.006 ENST00000370648.3
 BRS3
bombesin-like receptor 3
chr8_-_91095099 0.005 ENST00000265431.3
 CALB1
calbindin 1, 28kDa
chr1_-_41131326 0.005 ENST00000372684.3
 RIMS3
regulating synaptic membrane exocytosis 3
chr4_+_86396321 0.005 ENST00000503995.1
 ARHGAP24
Rho GTPase activating protein 24
chr12_+_16500037 0.005 ENST00000536371.1
ENST00000010404.2
 MGST1

microsomal glutathione S-transferase 1

chr19_+_45147313 0.005 ENST00000406449.4
 PVR
poliovirus receptor
chr15_+_69854027 0.005 ENST00000498938.2
 RP11-279F6.1
RP11-279F6.1
chr13_-_72441315 0.005 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
 DACH1


dachshund homolog 1 (Drosophila)


chr11_-_128775592 0.004 ENST00000310799.3
 C11orf45
chromosome 11 open reading frame 45
chr18_+_55018044 0.004 ENST00000324000.3
 ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr2_+_87755054 0.004 ENST00000423846.1
 LINC00152
long intergenic non-protein coding RNA 152
chr12_-_10601963 0.004 ENST00000543893.1
 KLRC1
killer cell lectin-like receptor subfamily C, member 1
chr17_-_42908155 0.003 ENST00000426548.1
ENST00000590758.1
ENST00000591424.1
 GJC1


gap junction protein, gamma 1, 45kDa


chr3_+_48413709 0.003 ENST00000296438.5
ENST00000436231.1
ENST00000445170.1
ENST00000415155.1
 FBXW12



F-box and WD repeat domain containing 12



chr4_+_76995855 0.003 ENST00000355810.4
ENST00000349321.3
 ART3

ADP-ribosyltransferase 3

chr12_-_62997214 0.003 ENST00000408887.2
 C12orf61
chromosome 12 open reading frame 61
chr12_+_20522179 0.003 ENST00000359062.3
 PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr17_+_47439733 0.002 ENST00000507337.1
 RP11-1079K10.3
RP11-1079K10.3
chr8_-_130799134 0.002 ENST00000276708.4
 GSDMC
gasdermin C
chr3_+_50649302 0.002 ENST00000446044.1
 MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr3_-_50649192 0.002 ENST00000443053.2
ENST00000348721.3
 CISH

cytokine inducible SH2-containing protein

chr7_+_23719749 0.001 ENST00000409192.3
ENST00000344962.4
ENST00000409653.1
ENST00000409994.3
 FAM221A



family with sequence similarity 221, member A



chr8_+_67039131 0.001 ENST00000315962.4
ENST00000353317.5
 TRIM55

tripartite motif containing 55

chr6_+_150690028 0.001 ENST00000229447.5
ENST00000344419.3
 IYD

iodotyrosine deiodinase

chr9_-_117880477 0.001 ENST00000534839.1
ENST00000340094.3
ENST00000535648.1
ENST00000346706.3
ENST00000345230.3
ENST00000350763.4
 TNC





tenascin C





chr15_-_75871589 0.001 ENST00000306726.2
 PTPN9
protein tyrosine phosphatase, non-receptor type 9
chr15_-_49913126 0.001 ENST00000561064.1
ENST00000299338.6
 FAM227B

family with sequence similarity 227, member B

chr17_+_66539369 0.000 ENST00000600820.1
 AC079210.1
Uncharacterized protein; cDNA FLJ45097 fis, clone BRAWH3031054
chrX_+_95939638 0.000 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
 DIAPH2


diaphanous-related formin 2



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.1 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.0 0.5 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:1903519 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.0 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:1903979 negative regulation of microglial cell activation(GO:1903979)
0.0 0.1 GO:2001183 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:1903826 arginine transmembrane transport(GO:1903826)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.0 GO:0032002 interleukin-28 receptor complex(GO:0032002)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.0 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR