Motif ID: BARHL2

Z-value: 1.254


Transcription factors associated with BARHL2:

Gene SymbolEntrez IDGene Name
BARHL2 ENSG00000143032.7 BARHL2



Activity profile for motif BARHL2.

activity profile for motif BARHL2


Sorted Z-values histogram for motif BARHL2

Sorted Z-values for motif BARHL2



Network of associatons between targets according to the STRING database.



First level regulatory network of BARHL2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_165555200 3.866 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE



butyrylcholinesterase



chr6_-_64029879 3.089 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN


lengsin, lens protein with glutamine synthetase domain


chr4_-_186570679 2.082 ENST00000451974.1
SORBS2
sorbin and SH3 domain containing 2
chr7_-_137028534 2.080 ENST00000348225.2
PTN
pleiotrophin
chr7_-_137028498 1.927 ENST00000393083.2
PTN
pleiotrophin
chr18_-_33702078 1.816 ENST00000586829.1
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr16_-_46797149 1.663 ENST00000536476.1
MYLK3
myosin light chain kinase 3
chr13_+_30002741 1.589 ENST00000380808.2
MTUS2
microtubule associated tumor suppressor candidate 2
chr4_-_110723194 1.587 ENST00000394635.3
CFI
complement factor I
chr16_-_46782221 1.562 ENST00000394809.4
MYLK3
myosin light chain kinase 3
chr2_-_183387064 1.557 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A



phosphodiesterase 1A, calmodulin-dependent



chr13_+_30002846 1.502 ENST00000542829.1
MTUS2
microtubule associated tumor suppressor candidate 2
chr1_+_186265399 1.485 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
PRG4






proteoglycan 4






chr6_-_116833500 1.445 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr8_+_19796381 1.444 ENST00000524029.1
ENST00000522701.1
ENST00000311322.8
LPL


lipoprotein lipase


chr8_+_128426535 1.430 ENST00000465342.2
POU5F1B
POU class 5 homeobox 1B
chr18_-_48351743 1.359 ENST00000588444.1
ENST00000256425.2
ENST00000428869.2
MRO


maestro


chr2_-_183387430 1.357 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr10_+_18629628 1.299 ENST00000377329.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr7_-_138363824 1.291 ENST00000419765.3
SVOPL
SVOP-like
chr19_+_39687596 1.274 ENST00000339852.4
NCCRP1
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chr18_-_33709268 1.269 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6


solute carrier family 39 (zinc transporter), member 6


chr12_-_91576561 1.233 ENST00000547568.2
ENST00000552962.1
DCN

decorin

chr3_+_167453493 1.109 ENST00000295777.5
ENST00000472747.2
SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

chr2_-_183387283 1.061 ENST00000435564.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chrX_+_77154935 1.054 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb
chr5_-_24645078 1.044 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr4_-_90756769 1.038 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA


synuclein, alpha (non A4 component of amyloid precursor)


chr3_+_154798162 1.035 ENST00000360490.2
MME
membrane metallo-endopeptidase
chr3_+_154801678 0.977 ENST00000462837.1
MME
membrane metallo-endopeptidase
chr10_-_61900762 0.969 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr6_-_134639235 0.925 ENST00000533224.1
SGK1
serum/glucocorticoid regulated kinase 1
chr3_+_154801312 0.917 ENST00000497890.1
MME
membrane metallo-endopeptidase
chr5_-_41794313 0.916 ENST00000512084.1
OXCT1
3-oxoacid CoA transferase 1
chr12_-_71551868 0.908 ENST00000247829.3
TSPAN8
tetraspanin 8
chr22_-_36013368 0.879 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB



myoglobin



chr7_+_101460882 0.865 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
CUX1




cut-like homeobox 1




chr18_+_32173276 0.850 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA








dystrobrevin, alpha








chr6_-_99873145 0.820 ENST00000369239.5
ENST00000438806.1
PNISR

PNN-interacting serine/arginine-rich protein

chr11_+_12308447 0.809 ENST00000256186.2
MICALCL
MICAL C-terminal like
chrX_+_135252050 0.803 ENST00000449474.1
ENST00000345434.3
FHL1

four and a half LIM domains 1

chr17_-_47045949 0.793 ENST00000357424.2
GIP
gastric inhibitory polypeptide
chr8_-_128231299 0.788 ENST00000500112.1
CCAT1
colon cancer associated transcript 1 (non-protein coding)
chr7_-_111032971 0.785 ENST00000450877.1
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr8_+_101349823 0.755 ENST00000519566.1
KB-1991G8.1
KB-1991G8.1
chr1_-_151804222 0.752 ENST00000392697.3
RORC
RAR-related orphan receptor C
chr20_+_12989596 0.738 ENST00000434210.1
ENST00000399002.2
SPTLC3

serine palmitoyltransferase, long chain base subunit 3

chr2_-_188419078 0.727 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI



tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)



chr14_+_32798547 0.716 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6


A kinase (PRKA) anchor protein 6


chr21_+_22519416 0.709 ENST00000535285.1
NCAM2
neural cell adhesion molecule 2
chrX_+_135251783 0.703 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr1_-_220263096 0.700 ENST00000463953.1
ENST00000354807.3
ENST00000414869.2
ENST00000498237.2
ENST00000498791.2
ENST00000544404.1
ENST00000480959.2
ENST00000322067.7
BPNT1







3'(2'), 5'-bisphosphate nucleotidase 1







chr18_-_3220106 0.687 ENST00000356443.4
ENST00000400569.3
MYOM1

myomesin 1

chr14_-_70883708 0.669 ENST00000256366.4
SYNJ2BP
synaptojanin 2 binding protein
chrX_-_15511438 0.660 ENST00000380420.5
PIR
pirin (iron-binding nuclear protein)
chr4_-_186578674 0.649 ENST00000438278.1
SORBS2
sorbin and SH3 domain containing 2
chr1_+_104159999 0.645 ENST00000414303.2
ENST00000423678.1
AMY2A

amylase, alpha 2A (pancreatic)

chr5_-_79950775 0.645 ENST00000439211.2
DHFR
dihydrofolate reductase
chr19_-_6690723 0.644 ENST00000601008.1
C3
complement component 3
chr1_+_196788887 0.643 ENST00000367421.3
ENST00000320493.5
ENST00000367424.4
CFHR2
CFHR1

complement factor H-related 2
complement factor H-related 1

chr15_+_55700741 0.640 ENST00000569691.1
C15orf65
chromosome 15 open reading frame 65
chr17_-_7307358 0.629 ENST00000535512.1
ENST00000576017.1
ENST00000302422.3
TMEM256-PLSCR3
TMEM256

TMEM256-PLSCR3 readthrough (NMD candidate)
transmembrane protein 256

chr1_+_84767289 0.628 ENST00000394834.3
ENST00000370669.1
SAMD13

sterile alpha motif domain containing 13

chr10_-_50970382 0.627 ENST00000419399.1
ENST00000432695.1
OGDHL

oxoglutarate dehydrogenase-like

chr12_-_91505608 0.619 ENST00000266718.4
LUM
lumican
chr8_-_124553437 0.607 ENST00000517956.1
ENST00000443022.2
FBXO32

F-box protein 32

chr1_+_47489240 0.606 ENST00000371901.3
CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1
chr4_-_186732892 0.604 ENST00000451958.1
ENST00000439914.1
ENST00000428330.1
ENST00000429056.1
SORBS2



sorbin and SH3 domain containing 2



chr6_+_73076432 0.602 ENST00000414192.2
RIMS1
regulating synaptic membrane exocytosis 1
chr5_+_95066823 0.595 ENST00000506817.1
ENST00000379982.3
RHOBTB3

Rho-related BTB domain containing 3

chr15_-_64385981 0.579 ENST00000557835.1
ENST00000380290.3
ENST00000559950.1
FAM96A


family with sequence similarity 96, member A


chr9_-_5830768 0.573 ENST00000381506.3
ERMP1
endoplasmic reticulum metallopeptidase 1
chr4_+_183065793 0.572 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr9_-_5833027 0.570 ENST00000339450.5
ERMP1
endoplasmic reticulum metallopeptidase 1
chr6_+_26087509 0.564 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
HFE









hemochromatosis









chr18_+_21452804 0.549 ENST00000269217.6
LAMA3
laminin, alpha 3
chr18_+_21452964 0.547 ENST00000587184.1
LAMA3
laminin, alpha 3
chr8_-_97247759 0.541 ENST00000518406.1
ENST00000523920.1
ENST00000287022.5
UQCRB


ubiquinol-cytochrome c reductase binding protein


chr2_-_71454185 0.535 ENST00000244221.8
PAIP2B
poly(A) binding protein interacting protein 2B
chrX_-_15288154 0.533 ENST00000380483.3
ENST00000380485.3
ENST00000380488.4
ASB9


ankyrin repeat and SOCS box containing 9


chr11_+_64018955 0.531 ENST00000279230.6
ENST00000540288.1
ENST00000325234.5
PLCB3


phospholipase C, beta 3 (phosphatidylinositol-specific)


chr3_+_140981456 0.527 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr11_+_72983246 0.526 ENST00000393590.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr2_-_44550441 0.511 ENST00000420756.1
ENST00000444696.1
PREPL

prolyl endopeptidase-like

chr8_-_49833978 0.511 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr12_-_91576429 0.510 ENST00000552145.1
ENST00000546745.1
DCN

decorin

chr11_-_115158193 0.509 ENST00000543540.1
CADM1
cell adhesion molecule 1
chr22_-_31688431 0.508 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1



phosphoinositide-3-kinase interacting protein 1



chr3_-_98241358 0.504 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1



claudin domain containing 1



chrX_+_123097014 0.503 ENST00000394478.1
STAG2
stromal antigen 2
chr6_+_106546808 0.500 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chrX_-_117107680 0.500 ENST00000447671.2
ENST00000262820.3
KLHL13

kelch-like family member 13

chr6_+_43968306 0.499 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223


chromosome 6 open reading frame 223


chr14_+_73706308 0.497 ENST00000554301.1
ENST00000555445.1
PAPLN

papilin, proteoglycan-like sulfated glycoprotein

chrM_+_10053 0.490 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr12_-_102591604 0.489 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr12_-_71551652 0.489 ENST00000546561.1
TSPAN8
tetraspanin 8
chr3_-_157221128 0.485 ENST00000392833.2
ENST00000362010.2
VEPH1

ventricular zone expressed PH domain-containing 1

chr8_-_49834299 0.476 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr12_-_51422017 0.464 ENST00000394904.3
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr18_+_21529811 0.463 ENST00000588004.1
LAMA3
laminin, alpha 3
chr2_+_120189422 0.446 ENST00000306406.4
TMEM37
transmembrane protein 37
chrX_-_117107542 0.446 ENST00000371878.1
KLHL13
kelch-like family member 13
chrX_+_135251835 0.440 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr11_-_111649074 0.436 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr1_+_155278539 0.436 ENST00000447866.1
FDPS
farnesyl diphosphate synthase
chr12_-_75784669 0.435 ENST00000552497.1
ENST00000551829.1
ENST00000436898.1
ENST00000442339.2
CAPS2



calcyphosine 2



chr3_-_160117035 0.435 ENST00000489004.1
ENST00000496589.1
IFT80

intraflagellar transport 80 homolog (Chlamydomonas)

chr11_+_7618413 0.427 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr19_-_18654828 0.423 ENST00000609656.1
ENST00000597611.3
FKBP8

FK506 binding protein 8, 38kDa

chr12_+_110011571 0.422 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK


mevalonate kinase


chr14_-_23426337 0.421 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS4






HAUS augmin-like complex, subunit 4






chr9_-_28670283 0.418 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr9_-_7800067 0.418 ENST00000358227.4
TMEM261
transmembrane protein 261
chr6_-_75960024 0.410 ENST00000370081.2
COX7A2
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
chr5_+_136070614 0.409 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chr14_-_23426270 0.408 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS4



HAUS augmin-like complex, subunit 4



chr15_-_64386120 0.407 ENST00000300030.3
FAM96A
family with sequence similarity 96, member A
chr3_+_9944492 0.406 ENST00000383814.3
ENST00000454190.2
ENST00000454992.1
IL17RE


interleukin 17 receptor E


chr12_-_772901 0.403 ENST00000305108.4
NINJ2
ninjurin 2
chr12_-_54694807 0.402 ENST00000435572.2
NFE2
nuclear factor, erythroid 2
chr6_-_136788001 0.399 ENST00000544465.1
MAP7
microtubule-associated protein 7
chr10_-_50970322 0.399 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr6_-_134639180 0.395 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr1_-_244006528 0.394 ENST00000336199.5
ENST00000263826.5
AKT3

v-akt murine thymoma viral oncogene homolog 3

chr16_-_80926457 0.393 ENST00000563626.1
ENST00000562231.1
RP11-314O13.1

RP11-314O13.1

chr1_+_118148556 0.388 ENST00000369448.3
FAM46C
family with sequence similarity 46, member C
chr17_+_61151306 0.385 ENST00000580068.1
ENST00000580466.1
TANC2

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2

chr1_-_151762943 0.383 ENST00000368825.3
ENST00000368823.1
ENST00000458431.2
ENST00000368827.6
ENST00000368824.3
TDRKH




tudor and KH domain containing




chr5_+_81601166 0.382 ENST00000439350.1
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr16_+_53483983 0.376 ENST00000544545.1
RBL2
retinoblastoma-like 2 (p130)
chr1_+_32666188 0.375 ENST00000421922.2
CCDC28B
coiled-coil domain containing 28B
chr11_-_115127611 0.371 ENST00000545094.1
CADM1
cell adhesion molecule 1
chr11_-_111649015 0.371 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr2_+_135596180 0.369 ENST00000283054.4
ENST00000392928.1
ACMSD

aminocarboxymuconate semialdehyde decarboxylase

chr14_-_23426322 0.369 ENST00000555367.1
HAUS4
HAUS augmin-like complex, subunit 4
chr9_+_21409146 0.368 ENST00000380205.1
IFNA8
interferon, alpha 8
chr1_-_32801825 0.367 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr1_+_153747746 0.364 ENST00000368661.3
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr11_+_6411636 0.363 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
SMPD1


sphingomyelin phosphodiesterase 1, acid lysosomal


chr16_+_53412368 0.361 ENST00000565189.1
RP11-44F14.2
RP11-44F14.2
chr6_+_106534192 0.357 ENST00000369091.2
ENST00000369096.4
PRDM1

PR domain containing 1, with ZNF domain

chr14_-_23426231 0.354 ENST00000556915.1
HAUS4
HAUS augmin-like complex, subunit 4
chr18_-_21977748 0.345 ENST00000399441.4
ENST00000319481.3
OSBPL1A

oxysterol binding protein-like 1A

chr16_+_50300427 0.341 ENST00000394697.2
ENST00000566433.2
ENST00000538642.1
ADCY7


adenylate cyclase 7


chr5_-_74162605 0.337 ENST00000389156.4
ENST00000510496.1
ENST00000380515.3
FAM169A


family with sequence similarity 169, member A


chr6_+_26199737 0.337 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr7_+_16793160 0.336 ENST00000262067.4
TSPAN13
tetraspanin 13
chr1_+_207277590 0.333 ENST00000367070.3
C4BPA
complement component 4 binding protein, alpha
chr11_+_112041253 0.329 ENST00000532612.1
AP002884.3
AP002884.3
chr12_+_25205446 0.329 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP


lymphoid-restricted membrane protein


chr3_-_149095652 0.324 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chrX_+_119384607 0.324 ENST00000326624.2
ENST00000557385.1
ZBTB33

zinc finger and BTB domain containing 33

chr1_+_104104379 0.324 ENST00000435302.1
AMY2B
amylase, alpha 2B (pancreatic)
chr9_-_34620440 0.322 ENST00000421919.1
ENST00000378911.3
ENST00000477738.2
ENST00000341694.2
ENST00000259632.7
ENST00000378913.2
ENST00000378916.4
ENST00000447983.2
DCTN3







dynactin 3 (p22)







chr2_+_135596106 0.317 ENST00000356140.5
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr15_+_91411810 0.317 ENST00000268171.3
FURIN
furin (paired basic amino acid cleaving enzyme)
chr4_+_130017268 0.316 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
C4orf33


chromosome 4 open reading frame 33


chr4_-_22444733 0.315 ENST00000508133.1
GPR125
G protein-coupled receptor 125
chr3_-_178984759 0.311 ENST00000349697.2
ENST00000497599.1
KCNMB3

potassium large conductance calcium-activated channel, subfamily M beta member 3

chr11_+_6411670 0.309 ENST00000530395.1
ENST00000527275.1
SMPD1

sphingomyelin phosphodiesterase 1, acid lysosomal

chr18_-_3219847 0.307 ENST00000261606.7
MYOM1
myomesin 1
chr12_-_54694758 0.307 ENST00000553070.1
NFE2
nuclear factor, erythroid 2
chr18_+_29027696 0.306 ENST00000257189.4
DSG3
desmoglein 3
chr1_+_207277632 0.305 ENST00000421786.1
C4BPA
complement component 4 binding protein, alpha
chrM_+_9207 0.304 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr1_+_186798073 0.303 ENST00000367466.3
ENST00000442353.2
PLA2G4A

phospholipase A2, group IVA (cytosolic, calcium-dependent)

chrX_+_591524 0.302 ENST00000554971.1
ENST00000381575.1
SHOX

short stature homeobox

chr17_-_39093672 0.301 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23


keratin 23 (histone deacetylase inducible)


chr8_-_109260897 0.300 ENST00000521297.1
ENST00000519030.1
ENST00000521440.1
ENST00000518345.1
ENST00000519627.1
ENST00000220849.5
EIF3E





eukaryotic translation initiation factor 3, subunit E





chr15_-_55657428 0.300 ENST00000568543.1
CCPG1
cell cycle progression 1
chr1_-_190446759 0.300 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chrX_-_115594160 0.298 ENST00000371894.4
CXorf61
cancer/testis antigen 83
chr1_-_170043709 0.296 ENST00000367767.1
ENST00000361580.2
ENST00000538366.1
KIFAP3


kinesin-associated protein 3


chr8_-_116681221 0.293 ENST00000395715.3
TRPS1
trichorhinophalangeal syndrome I
chr1_+_109265033 0.291 ENST00000445274.1
FNDC7
fibronectin type III domain containing 7
chr15_+_76016293 0.284 ENST00000332145.2
ODF3L1
outer dense fiber of sperm tails 3-like 1
chr1_+_2066252 0.282 ENST00000466352.1
PRKCZ
protein kinase C, zeta
chr14_-_30766223 0.281 ENST00000549360.1
ENST00000508469.2
CTD-2251F13.1

CTD-2251F13.1

chr6_-_112081113 0.280 ENST00000517419.1
FYN
FYN oncogene related to SRC, FGR, YES
chr12_+_52056548 0.278 ENST00000545061.1
ENST00000355133.3
SCN8A

sodium channel, voltage gated, type VIII, alpha subunit

chr3_-_149093499 0.277 ENST00000472441.1
TM4SF1
transmembrane 4 L six family member 1
chr13_-_41706864 0.275 ENST00000379485.1
ENST00000499385.2
KBTBD6

kelch repeat and BTB (POZ) domain containing 6

chr7_-_130080977 0.273 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr17_-_55162360 0.271 ENST00000576871.1
ENST00000576313.1
RP11-166P13.3

RP11-166P13.3

chr5_+_150639360 0.271 ENST00000523004.1
GM2A
GM2 ganglioside activator
chr5_+_118788182 0.270 ENST00000515320.1
ENST00000510025.1
HSD17B4

hydroxysteroid (17-beta) dehydrogenase 4

chr5_-_78281623 0.265 ENST00000521117.1
ARSB
arylsulfatase B
chr2_+_173724771 0.264 ENST00000538974.1
ENST00000540783.1
RAPGEF4

Rap guanine nucleotide exchange factor (GEF) 4

chr12_+_56367697 0.262 ENST00000553116.1
ENST00000360299.5
ENST00000548068.1
ENST00000549915.1
ENST00000551459.1
ENST00000448789.2
RAB5B





RAB5B, member RAS oncogene family





chr4_-_122148620 0.262 ENST00000509841.1
TNIP3
TNFAIP3 interacting protein 3
chrX_+_22056165 0.262 ENST00000535894.1
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr20_+_11898507 0.261 ENST00000378226.2
BTBD3
BTB (POZ) domain containing 3
chr8_-_125486755 0.261 ENST00000499418.2
ENST00000530778.1
RNF139-AS1

RNF139 antisense RNA 1 (head to head)

chr4_-_170897045 0.257 ENST00000508313.1
RP11-205M3.3
RP11-205M3.3
chr12_-_91573132 0.256 ENST00000550563.1
ENST00000546370.1
DCN

decorin

chr12_-_10605929 0.256 ENST00000347831.5
ENST00000359151.3
KLRC1

killer cell lectin-like receptor subfamily C, member 1

chr6_+_135502501 0.255 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB






v-myb avian myeloblastosis viral oncogene homolog






chr7_+_99717230 0.255 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chr3_-_180397256 0.255 ENST00000442201.2
CCDC39
coiled-coil domain containing 39

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.8 3.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.6 3.2 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.4 3.9 GO:0009820 alkaloid metabolic process(GO:0009820)
0.3 1.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.3 0.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 0.9 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.3 2.9 GO:0071492 cellular response to UV-A(GO:0071492)
0.3 0.8 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 0.6 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.2 1.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.2 1.0 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.2 4.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 1.5 GO:0034371 chylomicron remodeling(GO:0034371)
0.2 0.6 GO:1903989 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.2 0.9 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2 1.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.2 1.3 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of high voltage-gated calcium channel activity(GO:1901843) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.2 1.0 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 0.6 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 0.4 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 2.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 3.1 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.8 GO:0010269 response to selenium ion(GO:0010269) regulation of glucagon secretion(GO:0070092)
0.1 0.3 GO:0061580 colon epithelial cell migration(GO:0061580)
0.1 0.7 GO:0015692 lead ion transport(GO:0015692)
0.1 0.9 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.9 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.9 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.3 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1 0.7 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 1.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.3 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.7 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.3 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 0.6 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.4 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 0.3 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.3 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 0.7 GO:0023021 termination of signal transduction(GO:0023021)
0.1 0.3 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 3.3 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.2 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.1 0.4 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.6 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 0.6 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.1 0.2 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.2 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 0.6 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1 0.2 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
0.1 1.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.2 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.5 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.6 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 0.2 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.3 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.4 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.5 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.8 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.2 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.7 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.2 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.3 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 0.7 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0045726 regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.2 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.1 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.2 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.0 1.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.0 0.2 GO:0007210 serotonin receptor signaling pathway(GO:0007210) positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.5 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.2 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.2 GO:0034370 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.7 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.9 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.3 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 1.0 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.2 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.1 GO:1903625 negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.1 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.2 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.2 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.0 0.1 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.3 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.6 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.7 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.4 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.2 GO:0046541 saliva secretion(GO:0046541)
0.0 0.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0060125 negative regulation of growth hormone secretion(GO:0060125) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.3 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 1.2 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 1.0 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.2 GO:0015846 polyamine transport(GO:0015846)
0.0 0.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.5 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 1.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.9 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.7 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.7 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.5 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.1 GO:0036343 psychomotor behavior(GO:0036343) motor behavior(GO:0061744)
0.0 0.1 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.0 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.0 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.0 0.1 GO:0003356 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356)
0.0 0.3 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.2 GO:0001763 morphogenesis of a branching structure(GO:0001763)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0032875 regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0021678 third ventricle development(GO:0021678)
0.0 0.1 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.0 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.2 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.0 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0035728 response to hepatocyte growth factor(GO:0035728)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 1.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.2 3.9 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 1.6 GO:0005610 laminin-5 complex(GO:0005610)
0.1 2.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.7 GO:0070826 paraferritin complex(GO:0070826)
0.1 1.6 GO:0070652 HAUS complex(GO:0070652)
0.1 0.5 GO:0071547 piP-body(GO:0071547)
0.1 1.0 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 1.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.4 GO:0030008 TRAPP complex(GO:0030008)
0.1 1.5 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 0.3 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.6 GO:1990357 terminal web(GO:1990357)
0.1 0.8 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.9 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 1.3 GO:0042627 chylomicron(GO:0042627)
0.1 1.5 GO:0043194 axon initial segment(GO:0043194)
0.1 0.5 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.3 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.1 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.6 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.7 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 4.1 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 3.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.7 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 1.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.3 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 3.5 GO:0044306 neuron projection terminus(GO:0044306)
0.0 0.0 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.2 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.9 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 1.0 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.0 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
1.0 3.9 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.8 3.2 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.6 4.0 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.4 1.4 GO:0017129 triglyceride binding(GO:0017129)
0.3 3.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 0.7 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.2 0.9 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.2 1.0 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.2 0.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.2 1.0 GO:0004556 alpha-amylase activity(GO:0004556)
0.2 1.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 1.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.8 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.7 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.6 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.7 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.6 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.4 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.3 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 0.3 GO:0031862 prostanoid receptor binding(GO:0031862)
0.1 0.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.3 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.5 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.2 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.1 3.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.5 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 3.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.2 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.8 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.6 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 1.9 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 1.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.2 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.1 0.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.3 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 1.1 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 1.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.2 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.5 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.2 GO:0050436 microfibril binding(GO:0050436)
0.0 0.4 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.6 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 3.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0004040 amidase activity(GO:0004040)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 1.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.7 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.4 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.5 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.6 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 1.0 GO:0030507 spectrin binding(GO:0030507)
0.0 0.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 2.9 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.5 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0050610 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.0 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.0 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.6 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 1.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.0 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.5 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 3.7 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.6 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.6 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 0.6 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.4 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.1 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.2 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 0.5 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.5 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.0 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.6 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.3 PID_ENDOTHELIN_PATHWAY Endothelins
0.0 0.2 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.4 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.9 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.0 0.9 PID_AURORA_B_PATHWAY Aurora B signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 4.4 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 3.1 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 2.8 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.1 2.4 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 1.6 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.0 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 0.7 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.9 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.2 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME_ADP_SIGNALLING_THROUGH_P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.8 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 1.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.0 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.2 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.7 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.6 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.2 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.0 1.1 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 1.8 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.2 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.7 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.5 REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.5 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.8 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.0 0.5 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR