Motif ID: ATF2_ATF1_ATF3

Z-value: 0.967

Transcription factors associated with ATF2_ATF1_ATF3:

Gene SymbolEntrez IDGene Name
ATF1 ENSG00000123268.4 ATF1
ATF2 ENSG00000115966.12 ATF2
ATF3 ENSG00000162772.12 ATF3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ATF2hg19_v2_chr2_-_176032843_176032941-0.771.5e-02Click!
ATF3hg19_v2_chr1_+_212738676_2127387550.771.6e-02Click!
ATF1hg19_v2_chr12_+_51158263_51158395-0.029.6e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of ATF2_ATF1_ATF3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_39781054 2.230 ENST00000463128.1
KRT17
keratin 17
chr17_-_39780819 2.227 ENST00000311208.8
KRT17
keratin 17
chr17_-_39780634 2.204 ENST00000577817.2
KRT17
keratin 17
chr2_+_70142232 1.518 ENST00000540449.1
MXD1
MAX dimerization protein 1
chr18_+_57567180 1.514 ENST00000316660.6
ENST00000269518.9
PMAIP1

phorbol-12-myristate-13-acetate-induced protein 1

chrX_+_92929192 1.458 ENST00000332647.4
FAM133A
family with sequence similarity 133, member A
chr2_+_70142189 1.358 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr15_+_89182178 1.298 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr4_+_75310851 1.242 ENST00000395748.3
ENST00000264487.2
AREG

amphiregulin

chr2_-_220408430 1.224 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr15_+_89182156 1.211 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr19_-_50979981 1.211 ENST00000595790.1
ENST00000600100.1
FAM71E1

family with sequence similarity 71, member E1

chr3_-_124653579 1.196 ENST00000478191.1
ENST00000311075.3
MUC13

mucin 13, cell surface associated

chr15_+_89181974 1.177 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr5_-_133304473 1.166 ENST00000231512.3
C5orf15
chromosome 5 open reading frame 15
chr16_+_3068393 1.144 ENST00000573001.1
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr8_+_38243967 1.138 ENST00000524874.1
ENST00000379957.4
ENST00000523983.2
LETM2


leucine zipper-EF-hand containing transmembrane protein 2


chr3_-_64211112 1.134 ENST00000295902.6
PRICKLE2
prickle homolog 2 (Drosophila)
chr11_+_3819049 1.126 ENST00000396986.2
ENST00000300730.6
ENST00000532535.1
ENST00000396993.4
ENST00000396991.2
ENST00000532523.1
ENST00000459679.1
ENST00000464261.1
ENST00000464906.2
ENST00000464441.1
PGAP2









post-GPI attachment to proteins 2









chr4_+_75311019 1.097 ENST00000502307.1
AREG
amphiregulin
chr19_+_45504688 1.027 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB


v-rel avian reticuloendotheliosis viral oncogene homolog B


chr1_+_228327943 1.025 ENST00000366726.1
ENST00000312726.4
ENST00000366728.2
ENST00000453943.1
ENST00000366723.1
ENST00000366722.1
ENST00000435153.1
ENST00000366721.1
GUK1







guanylate kinase 1







chr1_+_228327923 1.017 ENST00000391865.3
GUK1
guanylate kinase 1
chr17_-_49198216 0.968 ENST00000262013.7
ENST00000357122.4
SPAG9

sperm associated antigen 9

chr8_+_38243951 0.943 ENST00000297720.5
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chrX_+_44732757 0.932 ENST00000377967.4
ENST00000536777.1
ENST00000382899.4
ENST00000543216.1
KDM6A



lysine (K)-specific demethylase 6A



chr10_+_112257596 0.920 ENST00000369583.3
DUSP5
dual specificity phosphatase 5
chr4_+_75480629 0.910 ENST00000380846.3
AREGB
amphiregulin B
chr17_-_8059638 0.901 ENST00000584202.1
ENST00000354903.5
ENST00000577253.1
PER1


period circadian clock 1


chr6_+_32812568 0.884 ENST00000414474.1
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr3_-_134092561 0.864 ENST00000510560.1
ENST00000504234.1
ENST00000515172.1
AMOTL2


angiomotin like 2


chr1_-_183538319 0.859 ENST00000420553.1
ENST00000419402.1
NCF2

neutrophil cytosolic factor 2

chr17_-_49124230 0.856 ENST00000510283.1
ENST00000510855.1
SPAG9

sperm associated antigen 9

chr19_+_1941117 0.854 ENST00000255641.8
CSNK1G2
casein kinase 1, gamma 2
chr12_+_13044787 0.849 ENST00000534831.1
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr14_-_100841794 0.838 ENST00000556295.1
ENST00000554820.1
WARS

tryptophanyl-tRNA synthetase

chr16_+_29973351 0.828 ENST00000602948.1
ENST00000279396.6
ENST00000575829.2
ENST00000561899.2
TMEM219



transmembrane protein 219



chr14_-_100841670 0.806 ENST00000557297.1
ENST00000555813.1
ENST00000557135.1
ENST00000556698.1
ENST00000554509.1
ENST00000555410.1
WARS





tryptophanyl-tRNA synthetase





chr1_-_16482554 0.795 ENST00000358432.5
EPHA2
EPH receptor A2
chr14_-_100841930 0.785 ENST00000555031.1
ENST00000553395.1
ENST00000553545.1
ENST00000344102.5
ENST00000556338.1
ENST00000392882.2
ENST00000553934.1
WARS






tryptophanyl-tRNA synthetase






chr22_+_24236191 0.781 ENST00000215754.7
MIF
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr14_+_105219437 0.773 ENST00000329967.6
ENST00000347067.5
ENST00000553810.1
SIVA1


SIVA1, apoptosis-inducing factor


chr12_+_10365082 0.744 ENST00000545859.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr6_-_30181156 0.743 ENST00000418026.1
ENST00000416596.1
ENST00000453195.1
TRIM26


tripartite motif containing 26


chr16_+_31044413 0.734 ENST00000394998.1
STX4
syntaxin 4
chr17_-_49198095 0.727 ENST00000505279.1
SPAG9
sperm associated antigen 9
chr6_-_30181133 0.725 ENST00000454678.2
ENST00000434785.1
TRIM26

tripartite motif containing 26

chr1_+_35220613 0.710 ENST00000338513.1
GJB5
gap junction protein, beta 5, 31.1kDa
chr19_+_36203830 0.706 ENST00000262630.3
ZBTB32
zinc finger and BTB domain containing 32
chr2_-_220408260 0.700 ENST00000373891.2
CHPF
chondroitin polymerizing factor
chr1_+_156698743 0.694 ENST00000524343.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr7_-_944631 0.687 ENST00000453175.2
ADAP1
ArfGAP with dual PH domains 1
chr11_+_66610883 0.670 ENST00000309657.3
ENST00000524506.1
RCE1

Ras converting CAAX endopeptidase 1

chr19_+_42580274 0.669 ENST00000359044.4
ZNF574
zinc finger protein 574
chr5_-_66492562 0.661 ENST00000256447.4
CD180
CD180 molecule
chr6_-_3157760 0.651 ENST00000333628.3
TUBB2A
tubulin, beta 2A class IIa
chr9_-_128003606 0.645 ENST00000324460.6
HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr16_+_2022036 0.614 ENST00000568546.1
TBL3
transducin (beta)-like 3
chr12_+_54378849 0.605 ENST00000515593.1
HOXC10
homeobox C10
chr11_+_60609537 0.598 ENST00000227520.5
CCDC86
coiled-coil domain containing 86
chr1_+_36396791 0.582 ENST00000246314.6
AGO3
argonaute RISC catalytic component 3
chr9_-_130477912 0.579 ENST00000543175.1
PTRH1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr6_-_31671058 0.574 ENST00000538874.1
ENST00000395952.3
ABHD16A

abhydrolase domain containing 16A

chr19_-_47616992 0.570 ENST00000253048.5
ZC3H4
zinc finger CCCH-type containing 4
chr7_-_105926058 0.566 ENST00000417537.1
NAMPT
nicotinamide phosphoribosyltransferase
chr6_-_31670723 0.565 ENST00000440843.2
ENST00000375842.4
ABHD16A

abhydrolase domain containing 16A

chr21_-_44299626 0.560 ENST00000330317.2
ENST00000398208.2
WDR4

WD repeat domain 4

chr12_+_7282795 0.554 ENST00000266546.6
CLSTN3
calsyntenin 3
chr1_+_36554470 0.554 ENST00000373178.4
ADPRHL2
ADP-ribosylhydrolase like 2
chr8_+_94929168 0.552 ENST00000518107.1
ENST00000396200.3
PDP1

pyruvate dehyrogenase phosphatase catalytic subunit 1

chr11_+_65337901 0.548 ENST00000309328.3
ENST00000531405.1
ENST00000527920.1
ENST00000526877.1
ENST00000533115.1
ENST00000526433.1
SSSCA1





Sjogren syndrome/scleroderma autoantigen 1





chr8_+_94929110 0.544 ENST00000520728.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr7_-_45026159 0.540 ENST00000584327.1
ENST00000438705.3
SNHG15

small nucleolar RNA host gene 15 (non-protein coding)

chr8_+_94929077 0.539 ENST00000297598.4
ENST00000520614.1
PDP1

pyruvate dehyrogenase phosphatase catalytic subunit 1

chrX_-_77150985 0.535 ENST00000358075.6
MAGT1
magnesium transporter 1
chr1_+_36396677 0.531 ENST00000373191.4
ENST00000397828.2
AGO3

argonaute RISC catalytic component 3

chr8_+_23386557 0.530 ENST00000523930.1
SLC25A37
solute carrier family 25 (mitochondrial iron transporter), member 37
chr19_-_54974894 0.527 ENST00000333834.4
LENG9
leukocyte receptor cluster (LRC) member 9
chr1_+_36396313 0.524 ENST00000324350.5
AGO3
argonaute RISC catalytic component 3
chr12_+_56915713 0.524 ENST00000262031.5
ENST00000552247.2
RBMS2

RNA binding motif, single stranded interacting protein 2

chr17_-_4607335 0.524 ENST00000570571.1
ENST00000575101.1
ENST00000436683.2
ENST00000574876.1
PELP1



proline, glutamate and leucine rich protein 1



chr21_-_43430440 0.522 ENST00000398505.3
ENST00000310826.5
ENST00000449949.1
ENST00000398499.1
ENST00000398497.2
ENST00000398511.3
ZBTB21





zinc finger and BTB domain containing 21





chrX_-_77150911 0.521 ENST00000373336.3
MAGT1
magnesium transporter 1
chr12_+_56915776 0.518 ENST00000550726.1
ENST00000542360.1
RBMS2

RNA binding motif, single stranded interacting protein 2

chr2_+_220408724 0.517 ENST00000421791.1
ENST00000373883.3
ENST00000451952.1
TMEM198


transmembrane protein 198


chr1_-_1284730 0.513 ENST00000378888.5
DVL1
dishevelled segment polarity protein 1
chr8_+_17104401 0.509 ENST00000324815.3
ENST00000518038.1
VPS37A

vacuolar protein sorting 37 homolog A (S. cerevisiae)

chr11_-_68039364 0.505 ENST00000533310.1
ENST00000304271.6
ENST00000527280.1
C11orf24


chromosome 11 open reading frame 24


chr20_-_39317868 0.503 ENST00000373313.2
MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr8_+_94929273 0.500 ENST00000518573.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr21_-_35899113 0.498 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1


regulator of calcineurin 1


chr7_-_45026200 0.491 ENST00000577700.1
ENST00000580458.1
ENST00000579383.1
ENST00000584686.1
ENST00000585030.1
ENST00000582727.1
SNHG15





small nucleolar RNA host gene 15 (non-protein coding)





chr3_+_101546827 0.488 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ


nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta


chr16_+_67694849 0.482 ENST00000602551.1
ENST00000458121.2
ENST00000219255.3
PARD6A


par-6 family cell polarity regulator alpha


chr17_-_77813186 0.481 ENST00000448310.1
ENST00000269397.4
CBX4

chromobox homolog 4

chr17_-_15902951 0.477 ENST00000472495.1
ZSWIM7
zinc finger, SWIM-type containing 7
chr1_+_100503643 0.473 ENST00000370152.3
HIAT1
hippocampus abundant transcript 1
chr22_+_17082732 0.455 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
TPTEP1





transmembrane phosphatase with tensin homology pseudogene 1





chr15_+_59903975 0.450 ENST00000560585.1
ENST00000396065.1
GCNT3

glucosaminyl (N-acetyl) transferase 3, mucin type

chr11_-_65429891 0.449 ENST00000527874.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chrX_+_49832231 0.447 ENST00000376108.3
CLCN5
chloride channel, voltage-sensitive 5
chr12_+_131438496 0.445 ENST00000543826.1
GPR133
G protein-coupled receptor 133
chr19_-_19030157 0.440 ENST00000349893.4
ENST00000351079.4
ENST00000600932.1
ENST00000262812.4
COPE



coatomer protein complex, subunit epsilon



chr7_-_92777606 0.439 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L






sterile alpha motif domain containing 9-like






chr6_+_31916733 0.438 ENST00000483004.1
CFB
complement factor B
chr4_+_123747979 0.436 ENST00000608478.1
FGF2
fibroblast growth factor 2 (basic)
chr12_+_75874984 0.435 ENST00000550491.1
GLIPR1
GLI pathogenesis-related 1
chr12_+_113344755 0.435 ENST00000550883.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_-_102455846 0.435 ENST00000545679.1
CCDC53
coiled-coil domain containing 53
chr15_-_73075964 0.431 ENST00000563907.1
ADPGK
ADP-dependent glucokinase
chr8_-_103876340 0.431 ENST00000518353.1
AZIN1
antizyme inhibitor 1
chr1_-_89488510 0.430 ENST00000564665.1
ENST00000370481.4
GBP3

guanylate binding protein 3

chr2_+_113403434 0.429 ENST00000272542.3
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr11_-_119599794 0.424 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr4_+_119512928 0.422 ENST00000567913.2
RP11-384K6.6
RP11-384K6.6
chr7_+_138915102 0.417 ENST00000486663.1
UBN2
ubinuclein 2
chr15_+_59910132 0.414 ENST00000559200.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr19_+_45349630 0.414 ENST00000252483.5
PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr12_-_102455902 0.413 ENST00000240079.6
CCDC53
coiled-coil domain containing 53
chr14_+_61447832 0.412 ENST00000354886.2
ENST00000267488.4
SLC38A6

solute carrier family 38, member 6

chr2_+_241375069 0.411 ENST00000264039.2
GPC1
glypican 1
chr5_-_43313269 0.405 ENST00000511774.1
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr12_+_113344582 0.404 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
OAS1


2'-5'-oligoadenylate synthetase 1, 40/46kDa


chr14_-_23623577 0.403 ENST00000422941.2
ENST00000453702.1
SLC7A8

solute carrier family 7 (amino acid transporter light chain, L system), member 8

chr19_+_45349432 0.399 ENST00000252485.4
PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chrX_-_153237258 0.399 ENST00000310441.7
HCFC1
host cell factor C1 (VP16-accessory protein)
chr12_+_131438443 0.399 ENST00000261654.5
GPR133
G protein-coupled receptor 133
chr10_+_13203543 0.396 ENST00000378714.3
ENST00000479669.1
ENST00000484800.2
MCM10


minichromosome maintenance complex component 10


chr7_-_140624499 0.395 ENST00000288602.6
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr11_-_66056596 0.388 ENST00000471387.2
ENST00000359461.6
ENST00000376901.4
YIF1A


Yip1 interacting factor homolog A (S. cerevisiae)


chr4_+_123747834 0.388 ENST00000264498.3
FGF2
fibroblast growth factor 2 (basic)
chr4_+_111397216 0.387 ENST00000265162.5
ENPEP
glutamyl aminopeptidase (aminopeptidase A)
chr4_+_47487285 0.384 ENST00000273859.3
ENST00000504445.1
ATP10D

ATPase, class V, type 10D

chr17_-_47785504 0.378 ENST00000514907.1
ENST00000503334.1
ENST00000508520.1
SLC35B1


solute carrier family 35, member B1


chr17_+_26662679 0.377 ENST00000578158.1
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr19_-_42759300 0.376 ENST00000222329.4
ERF
Ets2 repressor factor
chr17_-_47785265 0.376 ENST00000511763.1
ENST00000515850.1
ENST00000415270.2
ENST00000240333.6
SLC35B1



solute carrier family 35, member B1



chr7_-_45026419 0.375 ENST00000578968.1
ENST00000580528.1
SNHG15

small nucleolar RNA host gene 15 (non-protein coding)

chr12_-_6982442 0.373 ENST00000523102.1
ENST00000524270.1
ENST00000519357.1
SPSB2


splA/ryanodine receptor domain and SOCS box containing 2


chr12_+_75874580 0.372 ENST00000456650.3
GLIPR1
GLI pathogenesis-related 1
chr19_+_59055814 0.370 ENST00000594806.1
ENST00000253024.5
ENST00000341753.6
TRIM28


tripartite motif containing 28


chr4_+_144434584 0.370 ENST00000283131.3
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr11_-_9482010 0.366 ENST00000596206.1
AC132192.1
LOC644656 protein; Uncharacterized protein
chr17_-_71308119 0.366 ENST00000439510.2
ENST00000581014.1
ENST00000579611.1
CDC42EP4


CDC42 effector protein (Rho GTPase binding) 4


chr16_+_4666475 0.363 ENST00000591895.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr15_-_74284613 0.362 ENST00000316911.6
ENST00000564777.1
ENST00000566081.1
ENST00000316900.5
STOML1



stomatin (EPB72)-like 1



chr11_-_64889649 0.362 ENST00000434372.2
FAU
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
chrX_-_153236819 0.358 ENST00000354233.3
HCFC1
host cell factor C1 (VP16-accessory protein)
chr9_-_123676827 0.357 ENST00000546084.1
TRAF1
TNF receptor-associated factor 1
chr19_-_50528584 0.355 ENST00000594092.1
ENST00000443401.2
ENST00000594948.1
ENST00000377011.2
ENST00000593919.1
ENST00000601324.1
ENST00000316763.3
ENST00000601341.1
ENST00000600259.1
VRK3








vaccinia related kinase 3








chr22_-_39096661 0.355 ENST00000216039.5
JOSD1
Josephin domain containing 1
chr9_+_34989638 0.354 ENST00000453597.3
ENST00000335998.3
ENST00000312316.5
DNAJB5


DnaJ (Hsp40) homolog, subfamily B, member 5


chr16_+_3115611 0.351 ENST00000530890.1
ENST00000444393.3
ENST00000533097.2
ENST00000008180.9
ENST00000396890.2
ENST00000525228.1
ENST00000548652.1
ENST00000525377.2
ENST00000530538.2
ENST00000549213.1
ENST00000552936.1
ENST00000548476.1
ENST00000552664.1
ENST00000552356.1
ENST00000551513.1
ENST00000382213.3
ENST00000548246.1
IL32
















interleukin 32
















chr5_-_43313574 0.351 ENST00000325110.6
ENST00000433297.2
HMGCS1

3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)

chr17_+_6915902 0.347 ENST00000570898.1
ENST00000552842.1
RNASEK

ribonuclease, RNase K

chr21_+_45209394 0.346 ENST00000497547.1
RRP1
ribosomal RNA processing 1
chr17_+_685513 0.345 ENST00000304478.4
RNMTL1
RNA methyltransferase like 1
chr14_+_61447927 0.340 ENST00000451406.1
SLC38A6
solute carrier family 38, member 6
chr16_-_67694597 0.338 ENST00000393919.4
ENST00000219251.8
ACD

adrenocortical dysplasia homolog (mouse)

chr7_-_65958525 0.337 ENST00000450353.1
ENST00000412091.1
GS1-124K5.3

GS1-124K5.3

chr19_-_49362621 0.332 ENST00000594195.1
ENST00000595867.1
PLEKHA4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr9_+_97488939 0.332 ENST00000277198.2
ENST00000297979.5
C9orf3

chromosome 9 open reading frame 3

chr17_-_43568062 0.329 ENST00000421073.2
ENST00000584420.1
ENST00000589780.1
ENST00000430334.3
PLEKHM1



pleckstrin homology domain containing, family M (with RUN domain) member 1



chr22_+_39101728 0.329 ENST00000216044.5
ENST00000484657.1
GTPBP1

GTP binding protein 1

chr14_+_88852059 0.328 ENST00000045347.7
SPATA7
spermatogenesis associated 7
chr22_-_19132154 0.326 ENST00000252137.6
DGCR14
DiGeorge syndrome critical region gene 14
chr10_+_104154229 0.324 ENST00000428099.1
ENST00000369966.3
NFKB2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

chr3_+_43328004 0.322 ENST00000454177.1
ENST00000429705.2
ENST00000296088.7
ENST00000437827.1
SNRK



SNF related kinase



chr17_-_43210580 0.322 ENST00000538093.1
ENST00000590644.1
PLCD3

phospholipase C, delta 3

chr19_+_4402659 0.321 ENST00000301280.5
ENST00000585854.1
CHAF1A

chromatin assembly factor 1, subunit A (p150)

chr14_+_88851874 0.318 ENST00000393545.4
ENST00000356583.5
ENST00000555401.1
ENST00000553885.1
SPATA7



spermatogenesis associated 7



chr19_+_18043810 0.316 ENST00000445755.2
CCDC124
coiled-coil domain containing 124
chr22_-_39096925 0.312 ENST00000456626.1
ENST00000412832.1
JOSD1

Josephin domain containing 1

chr1_+_173837488 0.310 ENST00000427304.1
ENST00000432989.1
ENST00000367702.1
ZBTB37


zinc finger and BTB domain containing 37


chr12_+_132628963 0.307 ENST00000330579.1
NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae)
chr17_-_73781567 0.306 ENST00000586607.1
H3F3B
H3 histone, family 3B (H3.3B)
chr12_-_10324716 0.306 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
OLR1



oxidized low density lipoprotein (lectin-like) receptor 1



chr22_-_39097527 0.305 ENST00000417712.1
JOSD1
Josephin domain containing 1
chr20_+_43992094 0.304 ENST00000453003.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr6_-_32098013 0.301 ENST00000375156.3
FKBPL
FK506 binding protein like
chr9_+_115983808 0.299 ENST00000374210.6
ENST00000374212.4
SLC31A1

solute carrier family 31 (copper transporter), member 1

chr2_+_74781828 0.299 ENST00000340004.6
DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr10_-_31320860 0.298 ENST00000436087.2
ENST00000442986.1
ENST00000413025.1
ENST00000452305.1
ZNF438



zinc finger protein 438



chr16_+_29911666 0.297 ENST00000563177.1
ENST00000483405.1
ASPHD1

aspartate beta-hydroxylase domain containing 1

chr13_+_49822041 0.297 ENST00000538056.1
ENST00000251108.6
ENST00000444959.1
ENST00000429346.1
CDADC1



cytidine and dCMP deaminase domain containing 1



chr16_+_3115378 0.296 ENST00000529550.1
ENST00000551122.1
ENST00000525643.2
ENST00000548807.1
ENST00000528163.2
IL32




interleukin 32




chr1_-_32110467 0.296 ENST00000440872.2
ENST00000373703.4
PEF1

penta-EF-hand domain containing 1

chr19_+_13056663 0.293 ENST00000541222.1
ENST00000316856.3
ENST00000586534.1
ENST00000592268.1
RAD23A



RAD23 homolog A (S. cerevisiae)



chr11_-_60719213 0.293 ENST00000227880.3
SLC15A3
solute carrier family 15 (oligopeptide transporter), member 3
chr18_+_77439775 0.292 ENST00000299543.7
ENST00000075430.7
CTDP1

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1

chr7_+_100464760 0.290 ENST00000200457.4
TRIP6
thyroid hormone receptor interactor 6
chr14_-_55369525 0.289 ENST00000543643.2
ENST00000536224.2
ENST00000395514.1
ENST00000491895.2
GCH1



GTP cyclohydrolase 1



chr12_+_27396901 0.288 ENST00000541191.1
ENST00000389032.3
STK38L

serine/threonine kinase 38 like

chr6_+_31783291 0.287 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
HSPA1A


heat shock 70kDa protein 1A


chr16_+_2563871 0.287 ENST00000330398.4
ENST00000568562.1
ENST00000569317.1
ATP6V0C

ATP6C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c

Uncharacterized protein
chr11_-_1593150 0.284 ENST00000397374.3
DUSP8
dual specificity phosphatase 8
chr11_-_65667884 0.284 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1


FOS-like antigen 1


chr4_-_2010562 0.284 ENST00000411649.1
ENST00000542778.1
ENST00000411638.2
ENST00000431323.1
NELFA



negative elongation factor complex member A



chr15_-_73076030 0.279 ENST00000311669.8
ADPGK
ADP-dependent glucokinase
chr11_+_111750206 0.279 ENST00000530214.1
ENST00000530799.1
C11orf1

chromosome 11 open reading frame 1


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.7 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.5 2.0 GO:0009183 purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
0.5 3.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.4 2.4 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.4 2.3 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.3 0.9 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.3 1.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.3 0.8 GO:0042660 positive regulation of cell fate specification(GO:0042660)
0.3 0.8 GO:0048320 axial mesoderm formation(GO:0048320)
0.3 0.8 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.2 0.7 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.2 6.6 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.2 0.7 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.2 0.9 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.2 1.5 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 1.5 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.2 0.8 GO:0036483 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.2 0.6 GO:1990108 protein linear deubiquitination(GO:1990108)
0.2 0.8 GO:0019046 release from viral latency(GO:0019046)
0.2 0.8 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.2 0.7 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 0.5 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.2 0.5 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2 0.8 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.1 0.6 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 1.2 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 0.6 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 0.3 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.1 0.1 GO:0051604 protein maturation(GO:0051604)
0.1 0.1 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.1 1.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 2.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.5 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.4 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.1 0.4 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264)
0.1 0.6 GO:1902728 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1 0.3 GO:0060381 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.1 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.5 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.1 0.7 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.6 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.3 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521)
0.1 0.3 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.1 0.3 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.2 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.1 0.5 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.3 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 0.7 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.4 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 0.3 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 0.3 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.1 0.6 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.1 0.3 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.1 1.4 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.1 0.4 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 0.3 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 0.3 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 0.4 GO:0002318 myeloid progenitor cell differentiation(GO:0002318) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.2 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1 0.8 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.2 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.1 0.2 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1 0.2 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.1 1.4 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.1 0.2 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.2 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.1 0.5 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.1 0.1 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 0.3 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.1 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.1 0.2 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 0.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.1 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.1 0.2 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.1 1.1 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.4 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 0.2 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 0.2 GO:0009182 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
0.1 0.3 GO:0030035 microspike assembly(GO:0030035)
0.1 0.3 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.1 0.2 GO:0060032 notochord regression(GO:0060032)
0.1 0.4 GO:0032202 telomere assembly(GO:0032202)
0.0 0.6 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.2 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.5 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.4 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.0 0.5 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.4 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.2 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.0 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.2 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0070512 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.0 0.1 GO:1904744 positive regulation of telomeric DNA binding(GO:1904744)
0.0 0.1 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.0 0.3 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.3 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 1.1 GO:0009642 response to light intensity(GO:0009642)
0.0 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.3 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.3 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.3 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.2 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.2 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.3 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.7 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.1 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.1 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.2 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.4 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.4 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.6 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.1 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.0 1.9 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.2 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.0 0.2 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.3 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.3 GO:0015677 copper ion import(GO:0015677) cellular response to cisplatin(GO:0072719)
0.0 0.2 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.0 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.0 0.1 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0071288 carbon dioxide transmembrane transport(GO:0035378) cellular response to mercury ion(GO:0071288)
0.0 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.7 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.0 0.4 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.1 GO:0060323 head morphogenesis(GO:0060323)
0.0 0.1 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.1 GO:0045658 eosinophil differentiation(GO:0030222) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.1 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 0.9 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.2 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0 0.6 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.6 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.1 GO:0046967 cytosol to ER transport(GO:0046967)
0.0 0.2 GO:0045743 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033) positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 1.4 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221) olfactory nerve development(GO:0021553)
0.0 0.2 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.4 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.4 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.0 0.1 GO:0097368 membrane to membrane docking(GO:0022614) establishment of Sertoli cell barrier(GO:0097368)
0.0 0.1 GO:0051958 methotrexate transport(GO:0051958)
0.0 0.0 GO:0043491 protein kinase B signaling(GO:0043491)
0.0 0.2 GO:0006116 NADH oxidation(GO:0006116)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.9 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.2 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.8 GO:0045730 respiratory burst(GO:0045730)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.4 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:1903939 regulation of TORC2 signaling(GO:1903939)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.0 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.4 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:1903517 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.6 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.3 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.1 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.0 0.1 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.2 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.1 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.2 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.2 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.0 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.3 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.1 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
0.0 0.1 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674) negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.1 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.1 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.0 0.3 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.1 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.0 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.0 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.0 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.7 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0035936 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.0 0.7 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.0 GO:0060492 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0 0.1 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.0 0.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.1 GO:1990441 negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
0.0 0.0 GO:0003165 Purkinje myocyte development(GO:0003165)
0.0 0.3 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.3 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.0 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.0 0.0 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.0 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.2 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.2 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.0 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.3 GO:0031033 myosin filament organization(GO:0031033)
0.0 0.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.0 0.0 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.0 0.0 GO:0052214 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) multi-organism catabolic process(GO:0044035) development involved in symbiotic interaction(GO:0044111) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.2 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.1 GO:0042713 sperm ejaculation(GO:0042713) Sertoli cell proliferation(GO:0060011)
0.0 0.4 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.2 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.0 GO:0007499 ectoderm and mesoderm interaction(GO:0007499) female genitalia morphogenesis(GO:0048807) cloacal septation(GO:0060197) positive regulation of somatic stem cell population maintenance(GO:1904674)
0.0 1.0 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 1.7 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.1 GO:2000765 regulation of cytoplasmic translation(GO:2000765) positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.1 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.0 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.0 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.0 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0 0.1 GO:0090344 negative regulation of cell aging(GO:0090344)
0.0 0.0 GO:0002188 translation reinitiation(GO:0002188)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.2 0.9 GO:0097196 Shu complex(GO:0097196)
0.1 1.5 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 0.9 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.3 GO:0030689 Noc complex(GO:0030689)
0.1 0.6 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 1.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.4 GO:0031213 RSF complex(GO:0031213)
0.1 0.9 GO:0032010 phagolysosome(GO:0032010)
0.1 1.1 GO:0000322 storage vacuole(GO:0000322)
0.1 0.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.3 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.5 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 1.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.9 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.4 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.1 0.3 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 0.3 GO:0001652 granular component(GO:0001652)
0.1 0.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.3 GO:0044393 microspike(GO:0044393)
0.0 1.0 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.6 GO:0070187 telosome(GO:0070187)
0.0 0.3 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 1.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0032021 NELF complex(GO:0032021)
0.0 0.5 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.3 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 7.2 GO:0005882 intermediate filament(GO:0005882)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.5 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.3 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.3 GO:1990393 3M complex(GO:1990393)
0.0 0.1 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 2.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.4 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.5 GO:1990909 Wnt signalosome(GO:1990909)
0.0 2.7 GO:0015030 Cajal body(GO:0015030)
0.0 0.4 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 1.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.8 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0030681 multimeric ribonuclease P complex(GO:0030681)
0.0 0.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.1 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.6 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.1 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.0 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 1.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 1.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 1.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.0 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.0 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.1 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.7 GO:0097542 ciliary tip(GO:0097542)
0.0 0.0 GO:0070993 translation preinitiation complex(GO:0070993)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0008859 exoribonuclease II activity(GO:0008859)
1.1 6.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.5 1.9 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.4 2.4 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.3 2.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3 0.9 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.3 0.8 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.2 1.5 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 0.8 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 0.6 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.2 2.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 0.8 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 1.0 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.5 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.1 0.8 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.1 0.4 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.1 0.4 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.1 0.9 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.3 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.3 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 0.5 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 1.0 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 1.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.5 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.3 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.1 0.3 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.1 0.7 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.7 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.4 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.1 0.2 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 0.3 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 1.0 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.2 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 1.1 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.6 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 1.4 GO:0035198 miRNA binding(GO:0035198)
0.1 0.2 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.1 0.5 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.2 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.0 0.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.2 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.5 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.4 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.8 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.2 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.0 0.1 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.0 0.3 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.6 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.2 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.3 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.3 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.9 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 0.7 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 2.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 1.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.2 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.7 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 2.8 GO:0043022 ribosome binding(GO:0043022)
0.0 0.5 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.7 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 1.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.2 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
0.0 0.1 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.0 0.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.2 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0070283 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 1.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0015350 methotrexate transporter activity(GO:0015350)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.6 GO:0032183 SUMO binding(GO:0032183)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.2 GO:0005497 androgen binding(GO:0005497)
0.0 0.2 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.6 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.0 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.3 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.5 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.0 GO:0015081 sodium ion transmembrane transporter activity(GO:0015081)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.0 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.9 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 0.2 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.0 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.1 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.0 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 2.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.0 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 1.5 GO:0051087 chaperone binding(GO:0051087)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 1.3 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 2.2 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.5 ST_STAT3_PATHWAY STAT3 Pathway
0.0 5.2 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 1.1 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 2.9 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 3.2 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.8 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 1.1 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.7 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.7 PID_IL12_2PATHWAY IL12-mediated signaling events
0.0 0.6 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.5 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.7 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 0.2 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 1.1 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.3 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.9 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.9 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.0 0.4 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 1.0 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.2 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.0 0.2 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 0.7 PID_NFAT_3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.0 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.6 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 0.8 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 0.6 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.5 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.9 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 4.4 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.0 REACTOME_DAG_AND_IP3_SIGNALING Genes involved in DAG and IP3 signaling
0.0 1.6 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.7 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 1.5 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.1 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.2 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.7 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.8 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 2.1 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.4 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.3 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.4 REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.2 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.1 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.4 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.5 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.8 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.9 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.4 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.6 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.1 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.8 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME_ER_PHAGOSOME_PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.4 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.2 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.6 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins