Motif ID: AR_NR3C2

Z-value: 0.477

Transcription factors associated with AR_NR3C2:

Gene SymbolEntrez IDGene Name
AR ENSG00000169083.11 AR
NR3C2 ENSG00000151623.10 NR3C2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ARhg19_v2_chrX_+_66764375_66764465-0.265.0e-01Click!
NR3C2hg19_v2_chr4_-_149363376_149363492-0.166.7e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of AR_NR3C2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_56642041 0.871 ENST00000245185.5
MT2A
metallothionein 2A
chr16_+_56642489 0.758 ENST00000561491.1
MT2A
metallothionein 2A
chr16_+_56716336 0.333 ENST00000394485.4
ENST00000562939.1
MT1X

metallothionein 1X

chr15_+_31658349 0.246 ENST00000558844.1
KLF13
Kruppel-like factor 13
chr16_-_787771 0.201 ENST00000568545.1
NARFL
nuclear prelamin A recognition factor-like
chr3_+_125985620 0.199 ENST00000511512.1
ENST00000512435.1
RP11-71E19.1

RP11-71E19.1

chr2_-_242576864 0.197 ENST00000407315.1
THAP4
THAP domain containing 4
chr16_-_787728 0.178 ENST00000567403.1
ENST00000562421.1
NARFL

nuclear prelamin A recognition factor-like

chr1_+_162335197 0.175 ENST00000431696.1
RP11-565P22.6
Uncharacterized protein
chr1_+_104104379 0.173 ENST00000435302.1
AMY2B
amylase, alpha 2B (pancreatic)
chr17_+_79071365 0.125 ENST00000576756.1
BAIAP2
BAI1-associated protein 2
chr8_-_145634666 0.118 ENST00000531042.1
CPSF1
cleavage and polyadenylation specific factor 1, 160kDa
chr2_-_75788424 0.116 ENST00000410071.1
EVA1A
eva-1 homolog A (C. elegans)
chr3_-_134093738 0.115 ENST00000506107.1
AMOTL2
angiomotin like 2
chr2_+_102953608 0.112 ENST00000311734.2
ENST00000409584.1
IL1RL1

interleukin 1 receptor-like 1

chr8_-_145634731 0.108 ENST00000349769.3
CPSF1
cleavage and polyadenylation specific factor 1, 160kDa
chr2_-_75788428 0.108 ENST00000432649.1
EVA1A
eva-1 homolog A (C. elegans)
chr11_-_506739 0.107 ENST00000529306.1
ENST00000438658.2
ENST00000527485.1
ENST00000397615.2
ENST00000397614.1
RNH1




ribonuclease/angiogenin inhibitor 1




chr19_+_56187987 0.105 ENST00000411543.2
EPN1
epsin 1
chr7_+_74379083 0.105 ENST00000361825.7
GATSL1
GATS protein-like 1
chr17_-_79304150 0.099 ENST00000574093.1
TMEM105
transmembrane protein 105
chr15_+_65204075 0.096 ENST00000380230.3
ENST00000357698.3
ENST00000395720.1
ENST00000496660.1
ENST00000319580.8
ANKDD1A




ankyrin repeat and death domain containing 1A




chr8_+_19759228 0.095 ENST00000520959.1
LPL
lipoprotein lipase
chr12_+_122241928 0.093 ENST00000604567.1
ENST00000542440.1
SETD1B

SET domain containing 1B

chr22_+_19939026 0.092 ENST00000406520.3
COMT
catechol-O-methyltransferase
chr19_-_42916499 0.085 ENST00000601189.1
ENST00000599211.1
LIPE

lipase, hormone-sensitive

chr11_-_506316 0.081 ENST00000532055.1
ENST00000531540.1
RNH1

ribonuclease/angiogenin inhibitor 1

chr19_-_3786354 0.076 ENST00000395040.2
ENST00000310132.6
MATK

megakaryocyte-associated tyrosine kinase

chr19_-_3786253 0.075 ENST00000585778.1
MATK
megakaryocyte-associated tyrosine kinase
chr14_-_23623577 0.075 ENST00000422941.2
ENST00000453702.1
SLC7A8

solute carrier family 7 (amino acid transporter light chain, L system), member 8

chr2_+_242577027 0.071 ENST00000402096.1
ENST00000404914.3
ATG4B

autophagy related 4B, cysteine peptidase

chr16_-_4852616 0.069 ENST00000591392.1
ENST00000587711.1
ROGDI

rogdi homolog (Drosophila)

chr2_+_242577097 0.063 ENST00000419606.1
ENST00000474739.2
ENST00000396411.3
ENST00000425239.1
ENST00000400771.3
ENST00000430617.2
ATG4B





autophagy related 4B, cysteine peptidase





chr10_+_60759378 0.063 ENST00000432535.1
LINC00844
long intergenic non-protein coding RNA 844
chr3_-_119396193 0.062 ENST00000484810.1
ENST00000497116.1
ENST00000261070.2
COX17


COX17 cytochrome c oxidase copper chaperone


chr3_+_13521665 0.057 ENST00000295757.3
ENST00000402259.1
ENST00000402271.1
ENST00000446613.2
ENST00000404548.1
ENST00000404040.1
HDAC11





histone deacetylase 11





chr13_-_40924439 0.057 ENST00000400432.3
RP11-172E9.2
RP11-172E9.2
chr19_-_14117074 0.056 ENST00000588885.1
ENST00000254325.4
RFX1

regulatory factor X, 1 (influences HLA class II expression)

chr19_+_54704610 0.056 ENST00000302907.4
RPS9
ribosomal protein S9
chr17_+_46918925 0.055 ENST00000502761.1
CALCOCO2
calcium binding and coiled-coil domain 2
chr9_-_35563896 0.053 ENST00000399742.2
FAM166B
family with sequence similarity 166, member B
chr16_-_67978016 0.051 ENST00000264005.5
LCAT
lecithin-cholesterol acyltransferase
chr11_-_114271139 0.051 ENST00000325636.4
C11orf71
chromosome 11 open reading frame 71
chr5_+_140186647 0.042 ENST00000512229.2
ENST00000356878.4
ENST00000530339.1
PCDHA4


protocadherin alpha 4


chr12_+_1099675 0.040 ENST00000545318.2
ERC1
ELKS/RAB6-interacting/CAST family member 1
chr4_+_186347388 0.039 ENST00000511138.1
ENST00000511581.1
C4orf47

chromosome 4 open reading frame 47

chr16_+_56672571 0.039 ENST00000290705.8
MT1A
metallothionein 1A
chr4_+_8442496 0.038 ENST00000389737.4
ENST00000504134.1
TRMT44

tRNA methyltransferase 44 homolog (S. cerevisiae)

chr1_-_27693349 0.037 ENST00000374040.3
ENST00000357582.2
ENST00000493901.1
MAP3K6


mitogen-activated protein kinase kinase kinase 6


chr19_-_14945933 0.035 ENST00000322301.3
OR7A5
olfactory receptor, family 7, subfamily A, member 5
chr12_-_56848426 0.035 ENST00000257979.4
MIP
major intrinsic protein of lens fiber
chr17_+_38498594 0.034 ENST00000394081.3
RARA
retinoic acid receptor, alpha
chr16_-_4852915 0.034 ENST00000322048.7
ROGDI
rogdi homolog (Drosophila)
chr8_-_110615669 0.033 ENST00000533394.1
SYBU
syntabulin (syntaxin-interacting)
chr12_-_122241812 0.033 ENST00000538335.1
AC084018.1
AC084018.1
chr17_-_3794021 0.032 ENST00000381769.2
CAMKK1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr19_-_8408139 0.031 ENST00000330915.3
ENST00000593649.1
ENST00000595639.1
KANK3


KN motif and ankyrin repeat domains 3


chr16_+_67207838 0.026 ENST00000566871.1
ENST00000268605.7
NOL3

nucleolar protein 3 (apoptosis repressor with CARD domain)

chr4_-_8442438 0.026 ENST00000356406.5
ENST00000413009.2
ACOX3

acyl-CoA oxidase 3, pristanoyl

chr12_-_106480587 0.026 ENST00000548902.1
NUAK1
NUAK family, SNF1-like kinase, 1
chr11_-_236326 0.024 ENST00000525237.1
ENST00000532956.1
ENST00000525319.1
ENST00000524564.1
ENST00000382743.4
SIRT3




sirtuin 3




chr13_+_113777105 0.024 ENST00000409306.1
ENST00000375551.3
ENST00000375559.3
F10


coagulation factor X


chr9_+_71650645 0.023 ENST00000396366.2
FXN
frataxin
chr5_-_149792295 0.022 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74



CD74 molecule, major histocompatibility complex, class II invariant chain



chr19_+_35741466 0.021 ENST00000599658.1
LSR
lipolysis stimulated lipoprotein receptor
chr2_-_73298802 0.021 ENST00000411783.1
ENST00000410065.1
ENST00000442582.1
ENST00000272433.2
SFXN5



sideroflexin 5



chr2_+_238395803 0.020 ENST00000264605.3
MLPH
melanophilin
chr12_+_52203789 0.018 ENST00000599343.1
AC068987.1
HCG1997999; cDNA FLJ33996 fis, clone DFNES2008881
chr16_+_67207872 0.018 ENST00000563258.1
ENST00000568146.1
NOL3

nucleolar protein 3 (apoptosis repressor with CARD domain)

chr2_-_27435634 0.017 ENST00000430186.1
SLC5A6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr4_+_37892682 0.017 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1


TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1


chr6_+_127898312 0.017 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr22_+_18632666 0.015 ENST00000215794.7
USP18
ubiquitin specific peptidase 18
chrX_+_2609317 0.015 ENST00000381187.3
ENST00000381184.1
CD99

CD99 molecule

chr6_+_123317116 0.015 ENST00000275162.5
CLVS2
clavesin 2
chr11_+_41736067 0.014 ENST00000528720.1
RP11-375D13.2
RP11-375D13.2
chr4_-_69215699 0.013 ENST00000510746.1
ENST00000344157.4
ENST00000355665.3
YTHDC1


YTH domain containing 1


chr19_+_1261106 0.013 ENST00000588411.1
CIRBP
cold inducible RNA binding protein
chrX_+_8432871 0.012 ENST00000381032.1
ENST00000453306.1
ENST00000444481.1
VCX3B


variable charge, X-linked 3B


chr2_-_27435390 0.012 ENST00000428518.1
SLC5A6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr8_-_23021533 0.011 ENST00000312584.3
TNFRSF10D
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr8_+_9046503 0.011 ENST00000512942.2
RP11-10A14.5
RP11-10A14.5
chr17_+_38333263 0.010 ENST00000456989.2
ENST00000543876.1
ENST00000544503.1
ENST00000264644.6
ENST00000538884.1
RAPGEFL1




Rap guanine nucleotide exchange factor (GEF)-like 1




chr1_-_10856694 0.010 ENST00000377022.3
ENST00000344008.5
CASZ1

castor zinc finger 1

chr4_-_76598052 0.010 ENST00000509100.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr10_+_48359344 0.009 ENST00000412534.1
ENST00000444585.1
ZNF488

zinc finger protein 488

chr17_-_14140166 0.008 ENST00000420162.2
ENST00000431716.2
CDRT15

CMT1A duplicated region transcript 15

chr14_+_105190514 0.008 ENST00000330877.2
ADSSL1
adenylosuccinate synthase like 1
chr11_+_236540 0.007 ENST00000532097.1
PSMD13
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr12_-_10251603 0.007 ENST00000457018.2
CLEC1A
C-type lectin domain family 1, member A
chr14_+_24616588 0.007 ENST00000324103.6
ENST00000559260.1
RNF31

ring finger protein 31

chr19_+_57874835 0.007 ENST00000282282.3
ENST00000543226.1
ENST00000596755.1
ENST00000597658.1
ZNF547
TRAPPC2P1

AC003002.4
zinc finger protein 547
trafficking protein particle complex 2 pseudogene 1

Uncharacterized protein
chr1_+_248524883 0.006 ENST00000366475.1
OR2T4
olfactory receptor, family 2, subfamily T, member 4
chr4_+_75311019 0.006 ENST00000502307.1
AREG
amphiregulin
chr3_+_52279737 0.005 ENST00000457351.2
PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr2_+_27435734 0.005 ENST00000419744.1
ATRAID
all-trans retinoic acid-induced differentiation factor
chr20_+_15177480 0.004 ENST00000402914.1
MACROD2
MACRO domain containing 2
chr10_-_375422 0.002 ENST00000434695.2
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr12_-_11002063 0.002 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
PRR4


proline rich 4 (lacrimal)


chrX_+_2609207 0.001 ENST00000381192.3
CD99
CD99 molecule
chrX_-_24045303 0.001 ENST00000328046.8
KLHL15
kelch-like family member 15
chr2_-_109605663 0.000 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
EDAR


ectodysplasin A receptor


chrX_+_2609356 0.000 ENST00000381180.3
ENST00000449611.1
CD99

CD99 molecule

chr4_-_69215467 0.000 ENST00000579690.1
YTHDC1
YTH domain containing 1
chr16_-_66584059 0.000 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
TK2





thymidine kinase 2, mitochondrial






Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 0.3 GO:0036018 cellular response to erythropoietin(GO:0036018)
0.0 0.4 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:0050668 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.0 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.0 0.1 GO:0034371 chylomicron remodeling(GO:0034371)
0.0 0.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0097361 CIA complex(GO:0097361)
0.0 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.2 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.2 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.1 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID_AP1_PATHWAY AP-1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.0 0.2 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate