Motif ID: AGUGCAA

Z-value: 0.970


Mature miRNA associated with seed AGUGCAA:

NamemiRBase Accession
hsa-miR-130a-3p MIMAT0000425
hsa-miR-130b-3p MIMAT0000691
hsa-miR-301a-3p MIMAT0000688
hsa-miR-301b-3p MIMAT0004958
hsa-miR-3666 MIMAT0018088
hsa-miR-4295 MIMAT0016844
hsa-miR-454-3p MIMAT0003885



Activity profile for motif AGUGCAA.

activity profile for motif AGUGCAA


Sorted Z-values histogram for motif AGUGCAA

Sorted Z-values for motif AGUGCAA



Network of associatons between targets according to the STRING database.



First level regulatory network of AGUGCAA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_178790057 1.289 ENST00000311417.2
ZMAT3
zinc finger, matrin-type 3
chr6_-_111136513 0.742 ENST00000368911.3
CDK19
cyclin-dependent kinase 19
chr3_+_4535025 0.716 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
ITPR1




inositol 1,4,5-trisphosphate receptor, type 1




chr9_+_101867359 0.685 ENST00000374994.4
TGFBR1
transforming growth factor, beta receptor 1
chr18_-_65184217 0.575 ENST00000310045.7
DSEL
dermatan sulfate epimerase-like
chr7_+_106809406 0.541 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HBP1



HMG-box transcription factor 1



chr7_+_116312411 0.495 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET


met proto-oncogene


chr9_-_140196703 0.478 ENST00000356628.2
NRARP
NOTCH-regulated ankyrin repeat protein
chr2_-_86564776 0.466 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1


receptor accessory protein 1


chr6_+_89790490 0.449 ENST00000336032.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr2_-_1748214 0.448 ENST00000433670.1
ENST00000425171.1
ENST00000252804.4
PXDN


peroxidasin homolog (Drosophila)


chr17_-_78450398 0.440 ENST00000306773.4
NPTX1
neuronal pentraxin I
chr3_-_141868357 0.414 ENST00000489671.1
ENST00000475734.1
ENST00000467072.1
ENST00000499676.2
TFDP2



transcription factor Dp-2 (E2F dimerization partner 2)



chr14_-_50698276 0.410 ENST00000216373.5
SOS2
son of sevenless homolog 2 (Drosophila)
chr16_-_87525651 0.407 ENST00000268616.4
ZCCHC14
zinc finger, CCHC domain containing 14
chr5_+_172068232 0.405 ENST00000520919.1
ENST00000522853.1
ENST00000369800.5
NEURL1B


neuralized E3 ubiquitin protein ligase 1B


chr6_-_16761678 0.398 ENST00000244769.4
ENST00000436367.1
ATXN1

ataxin 1

chr6_-_136871957 0.393 ENST00000354570.3
MAP7
microtubule-associated protein 7
chr12_+_56473628 0.393 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3


v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3


chr3_+_113666748 0.389 ENST00000330212.3
ENST00000498275.1
ZDHHC23

zinc finger, DHHC-type containing 23

chr1_+_12290121 0.389 ENST00000358136.3
ENST00000356315.4
VPS13D

vacuolar protein sorting 13 homolog D (S. cerevisiae)

chr4_-_140477928 0.387 ENST00000274031.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr1_+_36348790 0.387 ENST00000373204.4
AGO1
argonaute RISC catalytic component 1
chr4_+_184826418 0.383 ENST00000308497.4
ENST00000438269.1
STOX2

storkhead box 2

chr1_-_214724566 0.380 ENST00000366956.5
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr14_-_21493884 0.378 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG2






NDRG family member 2






chr5_+_122110691 0.367 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
SNX2


sorting nexin 2


chr2_-_180129484 0.358 ENST00000428443.3
SESTD1
SEC14 and spectrin domains 1
chr6_+_64281906 0.354 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr11_-_82782861 0.352 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
RAB30




RAB30, member RAS oncogene family




chr3_+_140950612 0.346 ENST00000286353.4
ENST00000502783.1
ENST00000393010.2
ENST00000514680.1
ACPL2



acid phosphatase-like 2



chr7_+_114562172 0.345 ENST00000393486.1
ENST00000257724.3
MDFIC

MyoD family inhibitor domain containing

chr2_+_192542850 0.342 ENST00000410026.2
NABP1
nucleic acid binding protein 1
chr2_-_2334888 0.341 ENST00000428368.2
ENST00000399161.2
MYT1L

myelin transcription factor 1-like

chr9_+_100263912 0.340 ENST00000259365.4
TMOD1
tropomodulin 1
chr19_-_17799008 0.338 ENST00000519716.2
UNC13A
unc-13 homolog A (C. elegans)
chr19_+_47421933 0.334 ENST00000404338.3
ARHGAP35
Rho GTPase activating protein 35
chr2_+_86947296 0.329 ENST00000283632.4
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr5_-_94620239 0.327 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr18_-_72921303 0.318 ENST00000322342.3
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr20_+_8112824 0.317 ENST00000378641.3
PLCB1
phospholipase C, beta 1 (phosphoinositide-specific)
chr5_+_112312416 0.316 ENST00000389063.2
DCP2
decapping mRNA 2
chr4_-_185747188 0.312 ENST00000507295.1
ENST00000504900.1
ENST00000281455.2
ENST00000454703.2
ACSL1



acyl-CoA synthetase long-chain family member 1



chr14_+_71374122 0.312 ENST00000304743.2
ENST00000238570.5
PCNX

pecanex homolog (Drosophila)

chr20_-_20693131 0.301 ENST00000202677.7
RALGAPA2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr17_-_76870222 0.300 ENST00000585421.1
TIMP2
TIMP metallopeptidase inhibitor 2
chr10_+_92980517 0.296 ENST00000336126.5
PCGF5
polycomb group ring finger 5
chr11_-_10315741 0.290 ENST00000256190.8
SBF2
SET binding factor 2
chr1_+_61547894 0.288 ENST00000403491.3
NFIA
nuclear factor I/A
chr1_-_95538492 0.288 ENST00000370205.5
ALG14
ALG14, UDP-N-acetylglucosaminyltransferase subunit
chr2_+_203879568 0.287 ENST00000449802.1
NBEAL1
neurobeachin-like 1
chrX_-_74376108 0.286 ENST00000339447.4
ENST00000373394.3
ENST00000529949.1
ENST00000534524.1
ENST00000253577.3
ABCB7




ATP-binding cassette, sub-family B (MDR/TAP), member 7




chrX_+_17393543 0.286 ENST00000380060.3
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr20_-_5591626 0.283 ENST00000379019.4
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr7_+_23636992 0.269 ENST00000307471.3
ENST00000409765.1
CCDC126

coiled-coil domain containing 126

chr6_+_136172820 0.267 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr4_-_89744457 0.267 ENST00000395002.2
FAM13A
family with sequence similarity 13, member A
chr2_-_106810783 0.265 ENST00000283148.7
UXS1
UDP-glucuronate decarboxylase 1
chr7_+_97736197 0.262 ENST00000297293.5
LMTK2
lemur tyrosine kinase 2
chr12_+_56367697 0.259 ENST00000553116.1
ENST00000360299.5
ENST00000548068.1
ENST00000549915.1
ENST00000551459.1
ENST00000448789.2
RAB5B





RAB5B, member RAS oncogene family





chr2_-_11484710 0.254 ENST00000315872.6
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chr3_-_176914238 0.251 ENST00000430069.1
ENST00000428970.1
TBL1XR1

transducin (beta)-like 1 X-linked receptor 1

chr8_-_116681221 0.248 ENST00000395715.3
TRPS1
trichorhinophalangeal syndrome I
chr10_+_95256356 0.246 ENST00000371485.3
CEP55
centrosomal protein 55kDa
chr14_-_34420259 0.243 ENST00000250457.3
ENST00000547327.2
EGLN3

egl-9 family hypoxia-inducible factor 3

chr8_+_59323823 0.243 ENST00000399598.2
UBXN2B
UBX domain protein 2B
chr16_-_18812746 0.242 ENST00000546206.2
ENST00000562819.1
ENST00000562234.2
ENST00000304414.7
ENST00000567078.2
ARL6IP1



RP11-1035H13.3
ADP-ribosylation factor-like 6 interacting protein 1



Uncharacterized protein
chr15_-_83316254 0.241 ENST00000567678.1
ENST00000450751.2
CPEB1

cytoplasmic polyadenylation element binding protein 1

chr14_-_35182994 0.238 ENST00000341223.3
CFL2
cofilin 2 (muscle)
chr4_-_53525406 0.236 ENST00000451218.2
ENST00000441222.3
USP46

ubiquitin specific peptidase 46

chrX_-_131352152 0.236 ENST00000342983.2
RAP2C
RAP2C, member of RAS oncogene family
chr8_+_42752053 0.235 ENST00000307602.4
HOOK3
hook microtubule-tethering protein 3
chrX_+_146993449 0.229 ENST00000218200.8
ENST00000370471.3
ENST00000370477.1
FMR1


fragile X mental retardation 1


chr6_+_139456226 0.228 ENST00000367658.2
HECA
headcase homolog (Drosophila)
chr10_-_102279586 0.226 ENST00000370345.3
ENST00000451524.1
ENST00000370329.5
SEC31B


SEC31 homolog B (S. cerevisiae)


chr5_+_96271141 0.225 ENST00000231368.5
LNPEP
leucyl/cystinyl aminopeptidase
chr1_-_22109682 0.220 ENST00000400301.1
ENST00000532737.1
USP48

ubiquitin specific peptidase 48

chr5_-_112630598 0.219 ENST00000302475.4
MCC
mutated in colorectal cancers
chr20_+_10199468 0.218 ENST00000254976.2
ENST00000304886.2
SNAP25

synaptosomal-associated protein, 25kDa

chrX_-_135056216 0.217 ENST00000305963.2
MMGT1
membrane magnesium transporter 1
chr8_+_17013515 0.217 ENST00000262096.8
ZDHHC2
zinc finger, DHHC-type containing 2
chr3_-_11762202 0.216 ENST00000445411.1
ENST00000404339.1
ENST00000273038.3
VGLL4


vestigial like 4 (Drosophila)


chr4_+_87856129 0.216 ENST00000395146.4
ENST00000507468.1
AFF1

AF4/FMR2 family, member 1

chr11_+_120894781 0.214 ENST00000529397.1
ENST00000528512.1
ENST00000422003.2
TBCEL


tubulin folding cofactor E-like


chr6_+_148663729 0.213 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr11_-_108093329 0.211 ENST00000278612.8
NPAT
nuclear protein, ataxia-telangiectasia locus
chr7_+_94139105 0.211 ENST00000297273.4
CASD1
CAS1 domain containing 1
chr12_+_65004292 0.211 ENST00000542104.1
ENST00000336061.2
RASSF3

Ras association (RalGDS/AF-6) domain family member 3

chr8_-_53626974 0.209 ENST00000435644.2
ENST00000518710.1
ENST00000025008.5
ENST00000517963.1
RB1CC1



RB1-inducible coiled-coil 1



chr18_+_9913977 0.207 ENST00000400000.2
ENST00000340541.4
VAPA

VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa

chr14_+_100705322 0.207 ENST00000262238.4
YY1
YY1 transcription factor
chr14_-_96830207 0.206 ENST00000359933.4
ATG2B
autophagy related 2B
chr12_-_50419177 0.200 ENST00000454520.2
ENST00000546595.1
ENST00000548824.1
ENST00000549777.1
ENST00000546723.1
ENST00000427314.2
ENST00000552157.1
ENST00000552310.1
ENST00000548644.1
ENST00000312377.5
ENST00000546786.1
ENST00000550149.1
ENST00000546764.1
ENST00000552004.1
ENST00000548320.1
ENST00000547905.1
ENST00000550651.1
ENST00000551145.1
ENST00000434422.1
ENST00000552921.1
RACGAP1



















Rac GTPase activating protein 1



















chr1_+_12227035 0.200 ENST00000376259.3
ENST00000536782.1
TNFRSF1B

tumor necrosis factor receptor superfamily, member 1B

chr8_+_11141925 0.199 ENST00000221086.3
MTMR9
myotubularin related protein 9
chrX_-_24045303 0.199 ENST00000328046.8
KLHL15
kelch-like family member 15
chr11_-_46940074 0.198 ENST00000378623.1
ENST00000534404.1
LRP4

low density lipoprotein receptor-related protein 4

chr11_+_32914579 0.197 ENST00000399302.2
QSER1
glutamine and serine rich 1
chr3_+_124223586 0.197 ENST00000393496.1
KALRN
kalirin, RhoGEF kinase
chr6_+_21593972 0.196 ENST00000244745.1
ENST00000543472.1
SOX4

SRY (sex determining region Y)-box 4

chr22_-_22221900 0.194 ENST00000215832.6
ENST00000398822.3
MAPK1

mitogen-activated protein kinase 1

chr3_-_87040233 0.189 ENST00000398399.2
VGLL3
vestigial like 3 (Drosophila)
chr18_+_19321281 0.189 ENST00000261537.6
MIB1
mindbomb E3 ubiquitin protein ligase 1
chr5_+_135468516 0.188 ENST00000507118.1
ENST00000511116.1
ENST00000545279.1
ENST00000545620.1
SMAD5



SMAD family member 5



chr14_-_57735528 0.187 ENST00000340918.7
ENST00000413566.2
EXOC5

exocyst complex component 5

chr20_-_32308028 0.186 ENST00000409299.3
ENST00000217398.3
ENST00000344022.3
PXMP4


peroxisomal membrane protein 4, 24kDa


chr2_-_101767715 0.186 ENST00000376840.4
ENST00000409318.1
TBC1D8

TBC1 domain family, member 8 (with GRAM domain)

chr7_-_139876812 0.186 ENST00000397560.2
JHDM1D
lysine (K)-specific demethylase 7A
chr14_-_47812321 0.185 ENST00000357362.3
ENST00000486952.2
ENST00000426342.1
MDGA2


MAM domain containing glycosylphosphatidylinositol anchor 2


chr9_-_27529726 0.180 ENST00000262244.5
MOB3B
MOB kinase activator 3B
chr1_-_68962782 0.179 ENST00000456315.2
DEPDC1
DEP domain containing 1
chr17_+_65821780 0.179 ENST00000321892.4
ENST00000335221.5
ENST00000306378.6
BPTF


bromodomain PHD finger transcription factor


chr12_-_122907091 0.177 ENST00000358808.2
ENST00000361654.4
ENST00000539080.1
ENST00000537178.1
CLIP1



CAP-GLY domain containing linker protein 1



chr5_-_133512683 0.176 ENST00000353411.6
SKP1
S-phase kinase-associated protein 1
chr2_+_173940442 0.176 ENST00000409176.2
ENST00000338983.3
ENST00000431503.2
MLTK


Mitogen-activated protein kinase kinase kinase MLT


chr20_+_11871371 0.175 ENST00000254977.3
BTBD3
BTB (POZ) domain containing 3
chr5_-_90679145 0.175 ENST00000265138.3
ARRDC3
arrestin domain containing 3
chr2_+_139259324 0.175 ENST00000280098.4
SPOPL
speckle-type POZ protein-like
chr9_+_74764340 0.173 ENST00000376986.1
ENST00000358399.3
GDA

guanine deaminase

chr2_-_172750733 0.173 ENST00000392592.4
ENST00000422440.2
SLC25A12

solute carrier family 25 (aspartate/glutamate carrier), member 12

chr11_+_120207787 0.173 ENST00000397843.2
ENST00000356641.3
ARHGEF12

Rho guanine nucleotide exchange factor (GEF) 12

chr4_+_153701081 0.172 ENST00000451320.2
ENST00000429148.2
ENST00000353617.2
ENST00000405727.2
ENST00000356064.3
ARFIP1




ADP-ribosylation factor interacting protein 1




chr12_-_51611477 0.172 ENST00000389243.4
POU6F1
POU class 6 homeobox 1
chr7_+_155089486 0.171 ENST00000340368.4
ENST00000344756.4
ENST00000425172.1
ENST00000342407.5
INSIG1



insulin induced gene 1



chr15_-_77363513 0.170 ENST00000267970.4
TSPAN3
tetraspanin 3
chr1_-_204380919 0.169 ENST00000367188.4
PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr7_+_91875508 0.168 ENST00000265742.3
ANKIB1
ankyrin repeat and IBR domain containing 1
chr18_-_51751132 0.167 ENST00000256429.3
MBD2
methyl-CpG binding domain protein 2
chr5_+_65222299 0.164 ENST00000284037.5
ERBB2IP
erbb2 interacting protein
chr10_-_124768300 0.164 ENST00000368886.5
IKZF5
IKAROS family zinc finger 5 (Pegasus)
chr8_+_38614807 0.163 ENST00000330691.6
ENST00000348567.4
TACC1

transforming, acidic coiled-coil containing protein 1

chr11_+_33278811 0.162 ENST00000303296.4
ENST00000379016.3
HIPK3

homeodomain interacting protein kinase 3

chr15_-_52030293 0.160 ENST00000560491.1
ENST00000267838.3
LYSMD2

LysM, putative peptidoglycan-binding, domain containing 2

chr10_-_105615164 0.158 ENST00000355946.2
ENST00000369774.4
SH3PXD2A

SH3 and PX domains 2A

chr10_-_73611046 0.158 ENST00000394934.1
ENST00000394936.3
PSAP

prosaposin

chr5_-_65017921 0.157 ENST00000381007.4
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr14_-_31676964 0.155 ENST00000553700.1
HECTD1
HECT domain containing E3 ubiquitin protein ligase 1
chr8_-_104427313 0.154 ENST00000297578.4
SLC25A32
solute carrier family 25 (mitochondrial folate carrier), member 32
chr14_-_75593708 0.154 ENST00000557673.1
ENST00000238616.5
NEK9

NIMA-related kinase 9

chr18_-_12657988 0.153 ENST00000410092.3
ENST00000409402.4
SPIRE1

spire-type actin nucleation factor 1

chr12_+_110906169 0.153 ENST00000377673.5
FAM216A
family with sequence similarity 216, member A
chr17_+_41177220 0.151 ENST00000587250.2
ENST00000544533.1
RND2

Rho family GTPase 2

chr1_+_145438469 0.150 ENST00000369317.4
TXNIP
thioredoxin interacting protein
chr11_-_110167352 0.149 ENST00000533991.1
ENST00000528498.1
ENST00000405097.1
ENST00000528900.1
ENST00000530301.1
ENST00000343115.4
RDX





radixin





chr2_-_86790593 0.147 ENST00000263856.4
ENST00000409225.2
CHMP3

charged multivesicular body protein 3

chr5_-_59189545 0.147 ENST00000340635.6
PDE4D
phosphodiesterase 4D, cAMP-specific
chr11_+_118307179 0.147 ENST00000534358.1
ENST00000531904.2
ENST00000389506.5
ENST00000354520.4
KMT2A



lysine (K)-specific methyltransferase 2A



chr5_+_80256453 0.144 ENST00000265080.4
RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr11_-_67980744 0.143 ENST00000401547.2
ENST00000453170.1
ENST00000304363.4
SUV420H1


suppressor of variegation 4-20 homolog 1 (Drosophila)


chr5_+_173315283 0.143 ENST00000265085.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr10_-_81205373 0.142 ENST00000372336.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr6_+_99282570 0.142 ENST00000328345.5
POU3F2
POU class 3 homeobox 2
chr3_+_179370517 0.140 ENST00000263966.3
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr2_+_196521458 0.138 ENST00000409086.3
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr8_-_17104356 0.138 ENST00000361272.4
ENST00000523917.1
CNOT7

CCR4-NOT transcription complex, subunit 7

chr15_+_50716576 0.138 ENST00000560297.1
ENST00000307179.4
ENST00000396444.3
ENST00000433963.1
ENST00000425032.3
USP8




ubiquitin specific peptidase 8




chr4_+_170541660 0.136 ENST00000513761.1
ENST00000347613.4
CLCN3

chloride channel, voltage-sensitive 3

chr17_-_7382834 0.136 ENST00000380599.4
ZBTB4
zinc finger and BTB domain containing 4
chr20_+_46130601 0.135 ENST00000341724.6
NCOA3
nuclear receptor coactivator 3
chr2_+_219745020 0.135 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr11_-_118661828 0.134 ENST00000264018.4
DDX6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr4_-_76598296 0.133 ENST00000395719.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr14_-_104029013 0.131 ENST00000299204.4
ENST00000557666.1
BAG5

BCL2-associated athanogene 5

chr1_+_78245303 0.131 ENST00000370791.3
ENST00000443751.2
FAM73A

family with sequence similarity 73, member A

chr1_+_110453203 0.131 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1


colony stimulating factor 1 (macrophage)


chr4_-_36246060 0.131 ENST00000303965.4
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr2_+_191273052 0.130 ENST00000417958.1
ENST00000432036.1
ENST00000392328.1
MFSD6


major facilitator superfamily domain containing 6


chr2_+_26256938 0.130 ENST00000264710.4
RAB10
RAB10, member RAS oncogene family
chr22_-_21213029 0.129 ENST00000572273.1
ENST00000255882.6
PI4KA

phosphatidylinositol 4-kinase, catalytic, alpha

chr13_+_52158610 0.129 ENST00000298125.5
WDFY2
WD repeat and FYVE domain containing 2
chr10_-_14590644 0.127 ENST00000378470.1
FAM107B
family with sequence similarity 107, member B
chr1_+_47799446 0.124 ENST00000371873.5
CMPK1
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr12_-_118541743 0.124 ENST00000359236.5
VSIG10
V-set and immunoglobulin domain containing 10
chr12_-_53893399 0.123 ENST00000267079.2
MAP3K12
mitogen-activated protein kinase kinase kinase 12
chr3_+_190231840 0.123 ENST00000072516.3
ENST00000443369.2
ENST00000412504.2
ENST00000439062.1
ENST00000447382.1
ENST00000422625.1
ENST00000422485.1
IL1RAP






interleukin 1 receptor accessory protein






chr18_-_19284724 0.122 ENST00000580981.1
ENST00000289119.2
ABHD3

abhydrolase domain containing 3

chr3_-_72496035 0.122 ENST00000477973.2
RYBP
RING1 and YY1 binding protein
chr9_-_107690420 0.121 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ABCA1


ATP-binding cassette, sub-family A (ABC1), member 1


chr4_+_86396265 0.121 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr2_+_173600671 0.119 ENST00000409036.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr6_-_99797522 0.117 ENST00000389677.5
FAXC
failed axon connections homolog (Drosophila)
chr5_-_40798263 0.116 ENST00000296800.4
ENST00000397128.2
PRKAA1

protein kinase, AMP-activated, alpha 1 catalytic subunit

chr10_+_89622870 0.115 ENST00000371953.3
PTEN
phosphatase and tensin homolog
chr1_-_52344471 0.114 ENST00000352171.7
ENST00000354831.7
NRD1

nardilysin (N-arginine dibasic convertase)

chr3_+_57261743 0.113 ENST00000288266.3
APPL1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr20_+_34700333 0.112 ENST00000441639.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr6_+_35182176 0.111 ENST00000394681.1
ENST00000274938.7
SCUBE3

signal peptide, CUB domain, EGF-like 3

chr12_+_70636765 0.109 ENST00000552231.1
ENST00000229195.3
ENST00000547780.1
ENST00000418359.3
CNOT2



CCR4-NOT transcription complex, subunit 2



chr6_-_170599561 0.109 ENST00000366756.3
DLL1
delta-like 1 (Drosophila)
chr2_-_200322723 0.109 ENST00000417098.1
SATB2
SATB homeobox 2
chr10_-_79686284 0.107 ENST00000372391.2
ENST00000372388.2
DLG5

discs, large homolog 5 (Drosophila)

chr2_-_225450013 0.107 ENST00000264414.4
CUL3
cullin 3
chr17_+_16284104 0.106 ENST00000577958.1
ENST00000302182.3
ENST00000577640.1
UBB


ubiquitin B


chr2_+_46926048 0.102 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chrX_-_153363188 0.102 ENST00000303391.6
MECP2
methyl CpG binding protein 2 (Rett syndrome)
chr11_-_31839488 0.102 ENST00000419022.1
ENST00000379132.3
ENST00000379129.2
PAX6


paired box 6


chr13_+_42846272 0.102 ENST00000025301.2
AKAP11
A kinase (PRKA) anchor protein 11
chr1_+_15943995 0.101 ENST00000480945.1
DDI2
DNA-damage inducible 1 homolog 2 (S. cerevisiae)
chr1_-_225615599 0.101 ENST00000421383.1
ENST00000272163.4
LBR

lamin B receptor

chr14_-_53417732 0.101 ENST00000399304.3
ENST00000395631.2
ENST00000341590.3
ENST00000343279.4
FERMT2



fermitin family member 2




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:1905075 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.1 0.7 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.3 GO:0080154 regulation of fertilization(GO:0080154)
0.1 0.6 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.3 GO:0033319 UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320)
0.1 0.2 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.2 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.1 0.4 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.5 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.3 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.1 0.4 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.2 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1 0.2 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.2 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 0.2 GO:0006147 guanine catabolic process(GO:0006147)
0.1 0.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.2 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 0.2 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.2 GO:0003357 noradrenergic neuron differentiation(GO:0003357) N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.2 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.3 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.2 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.4 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.2 GO:0015883 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.0 0.2 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.1 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.0 0.1 GO:1903984 negative regulation of ribosome biogenesis(GO:0090071) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.3 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.3 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:2000053 external genitalia morphogenesis(GO:0035261) canonical Wnt signaling pathway involved in neural crest cell differentiation(GO:0044335) Wnt signaling pathway involved in somitogenesis(GO:0090244) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.1 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.1 GO:1902228 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.4 GO:0060613 fat pad development(GO:0060613)
0.0 0.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.1 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.1 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.2 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.5 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.2 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.2 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.1 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.2 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.5 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.2 GO:0070649 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.1 GO:1990535 regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535)
0.0 0.4 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.4 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.3 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050) negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.0 0.2 GO:1903912 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.1 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.3 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.2 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.1 GO:0048698 regulation of collateral sprouting in absence of injury(GO:0048696) negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.0 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.0 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.1 GO:0046469 platelet activating factor metabolic process(GO:0046469)
0.0 0.3 GO:0072189 ureter development(GO:0072189)
0.0 0.0 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.3 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.3 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034657 GID complex(GO:0034657)
0.1 0.4 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.3 GO:0044305 calyx of Held(GO:0044305)
0.1 0.2 GO:1902737 dendritic filopodium(GO:1902737)
0.1 0.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.1 GO:0019034 viral replication complex(GO:0019034)
0.0 0.4 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.1 GO:0044094 host cell nuclear part(GO:0044094)
0.0 0.2 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0070876 SOSS complex(GO:0070876)
0.0 0.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.4 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0051286 cell tip(GO:0051286)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.6 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.3 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.6 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.4 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 0.3 GO:0048040 UDP-glucuronate decarboxylase activity(GO:0048040)
0.1 0.5 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.4 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.2 GO:0008892 guanine deaminase activity(GO:0008892)
0.1 0.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.3 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.0 0.2 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.1 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.1 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.1 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.0 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0071633 dihydroceramidase activity(GO:0071633)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.5 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.2 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.1 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 1.7 GO:0002039 p53 binding(GO:0002039)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.0 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.9 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.3 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.5 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 0.5 PID_ALK1_PATHWAY ALK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.1 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.3 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.5 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.4 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.5 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.1 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor