Motif ID: AGCAGCA

Z-value: 1.120


Mature miRNA associated with seed AGCAGCA:

NamemiRBase Accession
hsa-miR-15a-5p MIMAT0000068
hsa-miR-15b-5p MIMAT0000417
hsa-miR-16-5p MIMAT0000069
hsa-miR-195-5p MIMAT0000461
hsa-miR-424-5p MIMAT0001341
hsa-miR-497-5p MIMAT0002820
hsa-miR-6838-5p MIMAT0027578



Activity profile for motif AGCAGCA.

activity profile for motif AGCAGCA


Sorted Z-values histogram for motif AGCAGCA

Sorted Z-values for motif AGCAGCA



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCAGCA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_65613217 1.317 ENST00000545314.1
AK4
adenylate kinase 4
chr1_-_156786530 0.608 ENST00000368198.3
SH2D2A
SH2 domain containing 2A
chr8_-_67525473 0.563 ENST00000522677.3
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr15_+_67358163 0.523 ENST00000327367.4
SMAD3
SMAD family member 3
chr9_+_78505581 0.511 ENST00000376767.3
ENST00000376752.4
PCSK5

proprotein convertase subtilisin/kexin type 5

chr1_-_109940550 0.506 ENST00000256637.6
SORT1
sortilin 1
chr7_+_36429409 0.503 ENST00000265748.2
ANLN
anillin, actin binding protein
chr1_-_159869912 0.486 ENST00000368099.4
CCDC19
coiled-coil domain containing 19
chr3_-_66551351 0.477 ENST00000273261.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr17_+_57232690 0.445 ENST00000262293.4
PRR11
proline rich 11
chr7_-_95225768 0.426 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr7_-_92463210 0.421 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr4_+_123747834 0.406 ENST00000264498.3
FGF2
fibroblast growth factor 2 (basic)
chr8_+_87354945 0.403 ENST00000517970.1
WWP1
WW domain containing E3 ubiquitin protein ligase 1
chr3_-_120068143 0.395 ENST00000295628.3
LRRC58
leucine rich repeat containing 58
chr12_-_49449107 0.391 ENST00000301067.7
KMT2D
lysine (K)-specific methyltransferase 2D
chr1_+_171454659 0.391 ENST00000367742.3
ENST00000338920.4
PRRC2C

proline-rich coiled-coil 2C

chr14_+_31028329 0.384 ENST00000206595.6
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr11_-_65667884 0.367 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1


FOS-like antigen 1


chr1_+_36348790 0.360 ENST00000373204.4
AGO1
argonaute RISC catalytic component 1
chr1_-_120612240 0.356 ENST00000256646.2
NOTCH2
notch 2
chr8_+_25316489 0.354 ENST00000330560.3
CDCA2
cell division cycle associated 2
chr15_+_98503922 0.352 ENST00000268042.6
ARRDC4
arrestin domain containing 4
chr12_+_100967420 0.347 ENST00000266754.5
ENST00000547754.1
GAS2L3

growth arrest-specific 2 like 3

chr6_-_75915757 0.343 ENST00000322507.8
COL12A1
collagen, type XII, alpha 1
chr2_+_112812778 0.339 ENST00000283206.4
TMEM87B
transmembrane protein 87B
chr3_+_187930719 0.338 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr13_-_27745936 0.337 ENST00000282344.6
USP12
ubiquitin specific peptidase 12
chr12_+_68042495 0.335 ENST00000344096.3
DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr15_+_38544476 0.330 ENST00000299084.4
SPRED1
sprouty-related, EVH1 domain containing 1
chr1_+_78245303 0.326 ENST00000370791.3
ENST00000443751.2
FAM73A

family with sequence similarity 73, member A

chr21_+_35445827 0.313 ENST00000381151.3
ENST00000608209.1
SLC5A3
SLC5A3
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
sodium/myo-inositol cotransporter
chr15_+_69706585 0.312 ENST00000559279.1
ENST00000395392.2
KIF23

kinesin family member 23

chr2_-_217236750 0.311 ENST00000273067.4
MARCH4
membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
chr2_+_36582857 0.308 ENST00000280527.2
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr1_-_179198702 0.307 ENST00000502732.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr1_+_16174280 0.306 ENST00000375759.3
SPEN
spen family transcriptional repressor
chr17_-_65241281 0.302 ENST00000358691.5
ENST00000580168.1
HELZ

helicase with zinc finger

chr12_-_112037306 0.302 ENST00000535949.1
ENST00000542287.2
ENST00000377617.3
ENST00000550104.1
ATXN2



ataxin 2



chr10_-_119134918 0.298 ENST00000334464.5
PDZD8
PDZ domain containing 8
chr5_-_141704566 0.298 ENST00000344120.4
ENST00000434127.2
SPRY4

sprouty homolog 4 (Drosophila)

chr19_-_39523165 0.298 ENST00000509137.2
ENST00000292853.4
FBXO27

F-box protein 27

chr18_+_12947981 0.292 ENST00000262124.11
SEH1L
SEH1-like (S. cerevisiae)
chr5_+_127419449 0.291 ENST00000262461.2
ENST00000343225.4
SLC12A2

solute carrier family 12 (sodium/potassium/chloride transporter), member 2

chr2_+_110371905 0.287 ENST00000356454.3
SOWAHC
sosondowah ankyrin repeat domain family member C
chr11_+_118307179 0.285 ENST00000534358.1
ENST00000531904.2
ENST00000389506.5
ENST00000354520.4
KMT2A



lysine (K)-specific methyltransferase 2A



chr3_+_101504200 0.282 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr16_-_73082274 0.281 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr20_+_18447771 0.277 ENST00000377603.4
POLR3F
polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
chrX_-_109561294 0.276 ENST00000372059.2
ENST00000262844.5
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr1_-_225840747 0.275 ENST00000366843.2
ENST00000366844.3
ENAH

enabled homolog (Drosophila)

chr4_-_111119804 0.274 ENST00000394607.3
ENST00000302274.3
ELOVL6

ELOVL fatty acid elongase 6

chr3_-_72496035 0.268 ENST00000477973.2
RYBP
RING1 and YY1 binding protein
chr16_-_23160591 0.267 ENST00000219689.7
USP31
ubiquitin specific peptidase 31
chr7_+_140774032 0.267 ENST00000565468.1
TMEM178B
transmembrane protein 178B
chr17_+_65821780 0.267 ENST00000321892.4
ENST00000335221.5
ENST00000306378.6
BPTF


bromodomain PHD finger transcription factor


chr9_-_3525968 0.266 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
RFX3


regulatory factor X, 3 (influences HLA class II expression)


chr6_-_90529418 0.264 ENST00000439638.1
ENST00000369393.3
ENST00000428876.1
MDN1


MDN1, midasin homolog (yeast)


chr20_-_13765526 0.263 ENST00000202816.1
ESF1
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr9_-_127905736 0.262 ENST00000336505.6
ENST00000373549.4
SCAI

suppressor of cancer cell invasion

chr7_-_92219698 0.259 ENST00000438306.1
ENST00000445716.1
FAM133B

family with sequence similarity 133, member B

chr1_+_46668994 0.256 ENST00000371980.3
LURAP1
leucine rich adaptor protein 1
chr10_+_18948311 0.251 ENST00000377275.3
ARL5B
ADP-ribosylation factor-like 5B
chr11_-_89956461 0.251 ENST00000320585.6
CHORDC1
cysteine and histidine-rich domain (CHORD) containing 1
chr2_-_11484710 0.251 ENST00000315872.6
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chr22_+_45559722 0.248 ENST00000347635.4
ENST00000407019.2
ENST00000424634.1
ENST00000417702.1
ENST00000425733.2
ENST00000430547.1
NUP50





nucleoporin 50kDa





chr3_+_171758344 0.248 ENST00000336824.4
ENST00000423424.1
FNDC3B

fibronectin type III domain containing 3B

chr1_-_85666688 0.246 ENST00000341460.5
SYDE2
synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
chr16_+_30710462 0.246 ENST00000262518.4
ENST00000395059.2
ENST00000344771.4
SRCAP


Snf2-related CREBBP activator protein


chr13_-_30881621 0.245 ENST00000380615.3
KATNAL1
katanin p60 subunit A-like 1
chr2_-_161350305 0.244 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr1_+_10271674 0.244 ENST00000377086.1
KIF1B
kinesin family member 1B
chr12_-_63328817 0.243 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr18_+_29671812 0.236 ENST00000261593.3
ENST00000578914.1
RNF138

ring finger protein 138, E3 ubiquitin protein ligase

chr3_-_37217756 0.236 ENST00000440230.1
ENST00000421276.2
ENST00000421307.1
ENST00000354379.4
LRRFIP2



leucine rich repeat (in FLII) interacting protein 2



chr16_+_84853580 0.235 ENST00000262424.5
ENST00000566151.1
ENST00000567845.1
ENST00000564567.1
ENST00000569090.1
CRISPLD2




cysteine-rich secretory protein LCCL domain containing 2




chr1_-_154531095 0.234 ENST00000292211.4
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr1_+_2160134 0.230 ENST00000378536.4
SKI
v-ski avian sarcoma viral oncogene homolog
chr9_-_140196703 0.229 ENST00000356628.2
NRARP
NOTCH-regulated ankyrin repeat protein
chr15_-_66649010 0.227 ENST00000367709.4
ENST00000261881.4
TIPIN

TIMELESS interacting protein

chr2_-_227664474 0.226 ENST00000305123.5
IRS1
insulin receptor substrate 1
chr4_+_140222609 0.226 ENST00000296543.5
ENST00000398947.1
NAA15

N(alpha)-acetyltransferase 15, NatA auxiliary subunit

chr2_+_26568965 0.226 ENST00000260585.7
ENST00000447170.1
EPT1

ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)

chr13_-_21476900 0.225 ENST00000400602.2
ENST00000255305.6
XPO4

exportin 4

chr13_+_42846272 0.225 ENST00000025301.2
AKAP11
A kinase (PRKA) anchor protein 11
chr1_+_64239657 0.224 ENST00000371080.1
ENST00000371079.1
ROR1

receptor tyrosine kinase-like orphan receptor 1

chrX_+_119495934 0.223 ENST00000218008.3
ENST00000361319.3
ENST00000539306.1
ATP1B4


ATPase, Na+/K+ transporting, beta 4 polypeptide


chr14_-_100070363 0.222 ENST00000380243.4
CCDC85C
coiled-coil domain containing 85C
chr16_+_81348528 0.220 ENST00000568107.2
GAN
gigaxonin
chr10_-_120840309 0.215 ENST00000369144.3
EIF3A
eukaryotic translation initiation factor 3, subunit A
chrX_+_118108571 0.215 ENST00000304778.7
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr3_+_49977440 0.214 ENST00000442092.1
ENST00000266022.4
ENST00000443081.1
RBM6


RNA binding motif protein 6


chr4_+_128703295 0.213 ENST00000296464.4
ENST00000508549.1
HSPA4L

heat shock 70kDa protein 4-like

chr16_-_47007545 0.213 ENST00000317089.5
DNAJA2
DnaJ (Hsp40) homolog, subfamily A, member 2
chr12_-_112819896 0.212 ENST00000377560.5
ENST00000430131.2
ENST00000550722.1
ENST00000550724.1
HECTD4



HECT domain containing E3 ubiquitin protein ligase 4



chr3_-_42846021 0.210 ENST00000321331.7
HIGD1A
HIG1 hypoxia inducible domain family, member 1A
chrX_+_24483338 0.210 ENST00000379162.4
ENST00000441463.2
PDK3

pyruvate dehydrogenase kinase, isozyme 3

chrX_+_128674213 0.206 ENST00000371113.4
ENST00000357121.5
OCRL

oculocerebrorenal syndrome of Lowe

chr15_-_78526942 0.204 ENST00000258873.4
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr11_-_117186946 0.203 ENST00000313005.6
ENST00000528053.1
BACE1

beta-site APP-cleaving enzyme 1

chr1_-_109584608 0.202 ENST00000400794.3
ENST00000528747.1
ENST00000369962.3
ENST00000361054.3
WDR47



WD repeat domain 47



chr17_+_29421900 0.201 ENST00000358273.4
ENST00000356175.3
NF1

neurofibromin 1

chr4_+_166794383 0.201 ENST00000061240.2
ENST00000507499.1
TLL1

tolloid-like 1

chr10_+_105156364 0.199 ENST00000369797.3
PDCD11
programmed cell death 11
chr2_-_46385 0.198 ENST00000327669.4
FAM110C
family with sequence similarity 110, member C
chrX_+_150565653 0.198 ENST00000330374.6
VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr15_+_78441663 0.198 ENST00000299518.2
ENST00000558554.1
ENST00000557826.1
ENST00000561279.1
ENST00000559186.1
ENST00000560770.1
ENST00000559881.1
ENST00000559205.1
ENST00000441490.2
IDH3A








isocitrate dehydrogenase 3 (NAD+) alpha








chr7_+_99613195 0.196 ENST00000324306.6
ZKSCAN1
zinc finger with KRAB and SCAN domains 1
chr16_-_30798492 0.196 ENST00000262525.4
ZNF629
zinc finger protein 629
chr16_+_9185450 0.195 ENST00000327827.7
C16orf72
chromosome 16 open reading frame 72
chr8_+_22457127 0.195 ENST00000289989.5
C8orf58
chromosome 8 open reading frame 58
chr3_+_47324424 0.194 ENST00000437353.1
ENST00000232766.5
ENST00000455924.2
KLHL18


kelch-like family member 18


chr15_-_65809581 0.193 ENST00000341861.5
DPP8
dipeptidyl-peptidase 8
chrX_-_108976521 0.190 ENST00000469796.2
ENST00000502391.1
ENST00000508092.1
ENST00000340800.2
ENST00000348502.6
ACSL4




acyl-CoA synthetase long-chain family member 4




chr18_+_60190226 0.190 ENST00000269499.5
ZCCHC2
zinc finger, CCHC domain containing 2
chr11_+_101981169 0.189 ENST00000526343.1
ENST00000282441.5
ENST00000537274.1
ENST00000345877.2
YAP1



Yes-associated protein 1



chr6_-_130031358 0.189 ENST00000368149.2
ARHGAP18
Rho GTPase activating protein 18
chr2_-_128643496 0.187 ENST00000272647.5
AMMECR1L
AMMECR1-like
chr1_-_205719295 0.186 ENST00000367142.4
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chrX_+_21958674 0.186 ENST00000404933.2
SMS
spermine synthase
chr6_+_47445467 0.186 ENST00000359314.5
CD2AP
CD2-associated protein
chr12_-_31479045 0.185 ENST00000539409.1
ENST00000395766.1
FAM60A

family with sequence similarity 60, member A

chr1_+_113615794 0.184 ENST00000361127.5
LRIG2
leucine-rich repeats and immunoglobulin-like domains 2
chr1_-_19536744 0.183 ENST00000375267.2
ENST00000375217.2
ENST00000375226.2
ENST00000375254.3
UBR4



ubiquitin protein ligase E3 component n-recognin 4



chr12_-_39837192 0.182 ENST00000361961.3
ENST00000395670.3
KIF21A

kinesin family member 21A

chr1_-_23495340 0.180 ENST00000418342.1
LUZP1
leucine zipper protein 1
chr2_-_166060571 0.179 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr11_+_77300669 0.177 ENST00000313578.3
AQP11
aquaporin 11
chr19_+_47421933 0.177 ENST00000404338.3
ARHGAP35
Rho GTPase activating protein 35
chr12_-_12419703 0.177 ENST00000543091.1
ENST00000261349.4
LRP6

low density lipoprotein receptor-related protein 6

chr12_+_74931551 0.176 ENST00000519948.2
ATXN7L3B
ataxin 7-like 3B
chr9_-_123639600 0.175 ENST00000373896.3
PHF19
PHD finger protein 19
chr6_+_143929307 0.175 ENST00000427704.2
ENST00000305766.6
PHACTR2

phosphatase and actin regulator 2

chr3_+_196466710 0.175 ENST00000327134.3
PAK2
p21 protein (Cdc42/Rac)-activated kinase 2
chr1_+_47799446 0.174 ENST00000371873.5
CMPK1
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr1_-_156721502 0.174 ENST00000357325.5
HDGF
hepatoma-derived growth factor
chrX_-_24045303 0.173 ENST00000328046.8
KLHL15
kelch-like family member 15
chr7_+_32535060 0.171 ENST00000318709.4
ENST00000409301.1
ENST00000404479.1
AVL9


AVL9 homolog (S. cerevisiase)


chr8_+_37594130 0.171 ENST00000518526.1
ENST00000523887.1
ENST00000276461.5
ERLIN2


ER lipid raft associated 2


chr20_-_50159198 0.171 ENST00000371564.3
ENST00000396009.3
ENST00000610033.1
NFATC2


nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2


chr7_-_152133059 0.170 ENST00000262189.6
ENST00000355193.2
KMT2C

lysine (K)-specific methyltransferase 2C

chr3_-_53381539 0.169 ENST00000606822.1
ENST00000294241.6
ENST00000607628.1
DCP1A


decapping mRNA 1A


chr2_-_219925189 0.169 ENST00000295731.6
IHH
indian hedgehog
chrX_+_16804544 0.168 ENST00000380122.5
ENST00000398155.4
TXLNG

taxilin gamma

chr10_+_115614370 0.168 ENST00000369301.3
NHLRC2
NHL repeat containing 2
chr16_+_70148230 0.167 ENST00000398122.3
ENST00000568530.1
PDPR

pyruvate dehydrogenase phosphatase regulatory subunit

chr7_+_90032667 0.167 ENST00000496677.1
ENST00000287916.4
ENST00000535571.1
ENST00000394604.1
ENST00000394605.2
CLDN12




claudin 12




chr2_-_208030647 0.167 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr6_+_160390102 0.166 ENST00000356956.1
IGF2R
insulin-like growth factor 2 receptor
chr3_-_48229846 0.166 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
CDC25A


cell division cycle 25A


chr2_+_204571198 0.165 ENST00000374481.3
ENST00000458610.2
ENST00000324106.8
CD28


CD28 molecule


chr10_+_62538089 0.165 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
CDK1


cyclin-dependent kinase 1


chr4_+_15004165 0.164 ENST00000538197.1
ENST00000541112.1
ENST00000442003.2
CPEB2


cytoplasmic polyadenylation element binding protein 2


chr10_+_95256356 0.164 ENST00000371485.3
CEP55
centrosomal protein 55kDa
chr20_+_49348081 0.164 ENST00000371610.2
PARD6B
par-6 family cell polarity regulator beta
chr4_+_174089904 0.164 ENST00000265000.4
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr11_-_118023490 0.163 ENST00000324727.4
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chr14_+_37667118 0.161 ENST00000556615.1
ENST00000327441.7
ENST00000536774.1
MIPOL1


mirror-image polydactyly 1


chr5_-_95297678 0.161 ENST00000237853.4
ELL2
elongation factor, RNA polymerase II, 2
chr4_+_77870856 0.161 ENST00000264893.6
ENST00000502584.1
ENST00000510641.1
SEPT11


septin 11


chr8_-_124286735 0.161 ENST00000395571.3
ZHX1
zinc fingers and homeoboxes 1
chr17_+_56160768 0.160 ENST00000579991.2
DYNLL2
dynein, light chain, LC8-type 2
chr13_+_26828275 0.160 ENST00000381527.3
CDK8
cyclin-dependent kinase 8
chr11_+_69455855 0.160 ENST00000227507.2
ENST00000536559.1
CCND1

cyclin D1

chr2_+_108443388 0.160 ENST00000354986.4
ENST00000408999.3
RGPD4

RANBP2-like and GRIP domain containing 4

chr11_+_6411636 0.159 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
SMPD1


sphingomyelin phosphodiesterase 1, acid lysosomal


chr4_-_99851766 0.159 ENST00000450253.2
EIF4E
eukaryotic translation initiation factor 4E
chr3_+_196594727 0.158 ENST00000445299.2
ENST00000323460.5
ENST00000419026.1
SENP5


SUMO1/sentrin specific peptidase 5


chr5_+_52285144 0.158 ENST00000296585.5
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr17_+_40834580 0.155 ENST00000264638.4
CNTNAP1
contactin associated protein 1
chr5_-_132299313 0.155 ENST00000265343.5
AFF4
AF4/FMR2 family, member 4
chr9_-_138799070 0.155 ENST00000389532.4
ENST00000409386.3
CAMSAP1

calmodulin regulated spectrin-associated protein 1

chr2_-_55237484 0.154 ENST00000394609.2
RTN4
reticulon 4
chr16_+_53088885 0.153 ENST00000566029.1
ENST00000447540.1
CHD9

chromodomain helicase DNA binding protein 9

chr12_+_125478241 0.152 ENST00000341446.8
BRI3BP
BRI3 binding protein
chr14_-_74253948 0.152 ENST00000394071.2
ELMSAN1
ELM2 and Myb/SANT-like domain containing 1
chr12_+_122242597 0.151 ENST00000267197.5
SETD1B
SET domain containing 1B
chr14_-_104029013 0.150 ENST00000299204.4
ENST00000557666.1
BAG5

BCL2-associated athanogene 5

chr1_-_36235529 0.150 ENST00000318121.3
ENST00000373220.3
ENST00000520551.1
CLSPN


claspin


chr7_-_32931387 0.149 ENST00000304056.4
KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chr8_+_38614807 0.149 ENST00000330691.6
ENST00000348567.4
TACC1

transforming, acidic coiled-coil containing protein 1

chr12_+_22778009 0.149 ENST00000266517.4
ENST00000335148.3
ETNK1

ethanolamine kinase 1

chr18_+_67956135 0.149 ENST00000397942.3
SOCS6
suppressor of cytokine signaling 6
chr1_+_233463507 0.149 ENST00000366623.3
ENST00000366624.3
MLK4

Mitogen-activated protein kinase kinase kinase MLK4

chr6_+_30539153 0.149 ENST00000326195.8
ENST00000376545.3
ENST00000396515.4
ENST00000441867.1
ENST00000468958.1
ABCF1




ATP-binding cassette, sub-family F (GCN20), member 1




chr1_+_162467595 0.148 ENST00000538489.1
ENST00000489294.1
UHMK1

U2AF homology motif (UHM) kinase 1

chr15_-_49447835 0.148 ENST00000388901.5
ENST00000299259.6
COPS2

COP9 signalosome subunit 2

chr19_+_16771936 0.147 ENST00000187762.2
ENST00000599479.1
TMEM38A

transmembrane protein 38A

chr4_+_126237554 0.147 ENST00000394329.3
FAT4
FAT atypical cadherin 4
chr13_-_30169807 0.147 ENST00000380752.5
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr17_-_45266542 0.146 ENST00000531206.1
ENST00000527547.1
ENST00000446365.2
ENST00000575483.1
ENST00000066544.3
CDC27




cell division cycle 27




chr14_-_77843390 0.145 ENST00000216468.7
TMED8
transmembrane emp24 protein transport domain containing 8
chr15_+_59063478 0.145 ENST00000559228.1
ENST00000450403.2
FAM63B

family with sequence similarity 63, member B

chr12_-_14956396 0.144 ENST00000535328.1
ENST00000261167.2
WBP11

WW domain binding protein 11

chr17_+_68165657 0.143 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr10_-_28034989 0.143 ENST00000375790.5
MKX
mohawk homeobox
chr17_-_5487768 0.141 ENST00000269280.4
ENST00000345221.3
ENST00000262467.5
NLRP1


NLR family, pyrin domain containing 1


chr16_+_14726672 0.141 ENST00000261658.2
ENST00000563971.1
BFAR

bifunctional apoptosis regulator

chr16_-_74700737 0.140 ENST00000576652.1
ENST00000572337.1
ENST00000571750.1
ENST00000572990.1
ENST00000361070.4
RFWD3




ring finger and WD repeat domain 3




chr5_+_65440032 0.140 ENST00000334121.6
SREK1
splicing regulatory glutamine/lysine-rich protein 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0031106 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.1 1.5 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.1 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 0.4 GO:0042660 positive regulation of cell fate specification(GO:0042660)
0.1 0.1 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.1 0.3 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.5 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.3 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.1 0.3 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.5 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.3 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.3 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 0.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.4 GO:0001555 oocyte growth(GO:0001555)
0.1 0.3 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 0.2 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.1 0.2 GO:1904647 response to rotenone(GO:1904647)
0.1 0.2 GO:0021503 neural fold bending(GO:0021503)
0.1 0.2 GO:2000053 external genitalia morphogenesis(GO:0035261) canonical Wnt signaling pathway involved in neural crest cell differentiation(GO:0044335) Wnt signaling pathway involved in somitogenesis(GO:0090244) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1 0.5 GO:0001999 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001)
0.1 0.2 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 0.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.2 GO:0033341 regulation of collagen binding(GO:0033341)
0.0 0.1 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.0 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.4 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.3 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.3 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.8 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.2 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.0 0.4 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.3 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.3 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.0 0.2 GO:0015840 urea transport(GO:0015840)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.0 0.0 GO:0021896 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.1 GO:2001301 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.1 GO:0051029 rRNA transport(GO:0051029)
0.0 0.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 0.2 GO:0048478 replication fork protection(GO:0048478)
0.0 0.2 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.3 GO:0060413 atrial septum morphogenesis(GO:0060413)
0.0 0.2 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.2 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.0 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.1 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.0 GO:0071484 cellular response to light intensity(GO:0071484)
0.0 0.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.3 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.2 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.3 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.0 GO:0043618 positive regulation of transcription from RNA polymerase II promoter in response to stress(GO:0036003) positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091) regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618) regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.1 GO:1901090 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.2 GO:0002863 positive regulation of inflammatory response to antigenic stimulus(GO:0002863)
0.0 0.1 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.3 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.1 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.0 0.4 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.3 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.1 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.2 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.2 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.1 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.0 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:0010273 detoxification of copper ion(GO:0010273) regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759) stress response to copper ion(GO:1990169)
0.0 0.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.2 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.0 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.0 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.0 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.2 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.0 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.2 GO:0071205 protein localization to paranode region of axon(GO:0002175) protein localization to juxtaparanode region of axon(GO:0071205)
0.0 0.0 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.0 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413)
0.0 0.1 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.1 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.1 GO:0007440 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005595 collagen type XII trimer(GO:0005595)
0.1 0.5 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.2 GO:0043614 multi-eIF complex(GO:0043614)
0.1 0.3 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.2 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.0 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.1 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.2 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.0 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.1 GO:0035838 growing cell tip(GO:0035838)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.1 GO:0072517 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873) kinesin II complex(GO:0016939)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.0 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.2 GO:0033010 paranodal junction(GO:0033010)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.2 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 0.5 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.4 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.3 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.1 0.5 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.3 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.2 GO:0016768 spermine synthase activity(GO:0016768)
0.1 0.2 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.0 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 1.0 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.4 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.2 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.2 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0032767 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.2 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.2 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0003700 transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.2 GO:0005113 patched binding(GO:0005113)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.3 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.1 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.4 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 0.2 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.5 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.0 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 0.7 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.6 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.6 REACTOME_SOS_MEDIATED_SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.3 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.1 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 1.1 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.2 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.5 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.1 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.2 REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.3 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.2 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.6 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus