Motif ID: AGCACCA
Z-value: 1.188
Mature miRNA associated with seed AGCACCA:
| Name | miRBase Accession |
|---|---|
| hsa-miR-29a-3p | MIMAT0000086 |
| hsa-miR-29b-3p | MIMAT0000100 |
| hsa-miR-29c-3p | MIMAT0000681 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 2.1 | GO:0044691 | tooth eruption(GO:0044691) |
| 0.5 | 1.6 | GO:0070408 | carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718) |
| 0.3 | 0.8 | GO:0060981 | cell migration involved in coronary angiogenesis(GO:0060981) |
| 0.3 | 1.0 | GO:1990927 | vesicle-mediated cholesterol transport(GO:0090119) short-term synaptic potentiation(GO:1990926) calcium ion regulated lysosome exocytosis(GO:1990927) |
| 0.2 | 0.4 | GO:0060921 | sinoatrial node development(GO:0003163) sinoatrial node cell differentiation(GO:0060921) |
| 0.2 | 0.6 | GO:0071879 | positive regulation of adrenergic receptor signaling pathway(GO:0071879) |
| 0.2 | 0.5 | GO:1990709 | presynaptic active zone organization(GO:1990709) |
| 0.2 | 0.5 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.2 | 0.3 | GO:0060940 | epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) |
| 0.2 | 0.6 | GO:0070837 | dehydroascorbic acid transport(GO:0070837) |
| 0.2 | 1.4 | GO:0070235 | regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.2 | 1.2 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) chylomicron remodeling(GO:0034371) |
| 0.1 | 1.0 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 0.1 | 1.0 | GO:0072675 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 0.1 | 0.4 | GO:1904761 | negative regulation of myofibroblast differentiation(GO:1904761) |
| 0.1 | 0.5 | GO:2000302 | positive regulation of synaptic vesicle exocytosis(GO:2000302) |
| 0.1 | 0.3 | GO:1901860 | positive regulation of mitochondrial DNA metabolic process(GO:1901860) |
| 0.1 | 0.5 | GO:0002528 | regulation of vascular permeability involved in acute inflammatory response(GO:0002528) |
| 0.1 | 1.4 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.1 | 0.3 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
| 0.1 | 0.5 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 0.1 | 0.3 | GO:0006154 | adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103) |
| 0.1 | 0.4 | GO:0072255 | metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936) |
| 0.1 | 0.2 | GO:0032290 | peripheral nervous system myelin formation(GO:0032290) |
| 0.1 | 1.6 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.1 | 0.4 | GO:0060024 | rhythmic synaptic transmission(GO:0060024) |
| 0.1 | 0.6 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.1 | 0.3 | GO:0021823 | cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) |
| 0.1 | 1.2 | GO:0021542 | dentate gyrus development(GO:0021542) |
| 0.1 | 0.7 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
| 0.1 | 0.3 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
| 0.1 | 0.3 | GO:0016240 | autophagosome docking(GO:0016240) |
| 0.1 | 0.7 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.1 | 0.1 | GO:1903595 | positive regulation of histamine secretion by mast cell(GO:1903595) |
| 0.1 | 0.3 | GO:1901073 | N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073) |
| 0.1 | 0.5 | GO:0090116 | C-5 methylation of cytosine(GO:0090116) |
| 0.1 | 0.7 | GO:0071374 | cellular response to parathyroid hormone stimulus(GO:0071374) |
| 0.1 | 0.5 | GO:0044854 | plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836) |
| 0.1 | 0.2 | GO:2000588 | positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588) |
| 0.1 | 0.2 | GO:0033242 | regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283) |
| 0.1 | 0.3 | GO:0008050 | female courtship behavior(GO:0008050) negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
| 0.1 | 0.7 | GO:0033227 | dsRNA transport(GO:0033227) |
| 0.1 | 0.2 | GO:1904339 | negative regulation of dopaminergic neuron differentiation(GO:1904339) |
| 0.1 | 0.2 | GO:0010360 | negative regulation of anion channel activity(GO:0010360) Golgi to plasma membrane CFTR protein transport(GO:0043000) |
| 0.1 | 0.2 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.1 | 1.1 | GO:0044331 | cell-cell adhesion mediated by cadherin(GO:0044331) |
| 0.1 | 0.7 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.0 | 0.4 | GO:0034141 | positive regulation of toll-like receptor 3 signaling pathway(GO:0034141) |
| 0.0 | 0.2 | GO:0044028 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
| 0.0 | 0.3 | GO:0021943 | regulation of collagen catabolic process(GO:0010710) formation of radial glial scaffolds(GO:0021943) |
| 0.0 | 0.3 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 0.0 | 0.3 | GO:1903435 | positive regulation of constitutive secretory pathway(GO:1903435) |
| 0.0 | 0.4 | GO:1903912 | negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912) |
| 0.0 | 0.2 | GO:0035617 | stress granule disassembly(GO:0035617) |
| 0.0 | 0.2 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
| 0.0 | 0.1 | GO:0098972 | dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972) |
| 0.0 | 0.4 | GO:0060159 | regulation of dopamine receptor signaling pathway(GO:0060159) |
| 0.0 | 0.1 | GO:0010621 | negative regulation of transcription by transcription factor localization(GO:0010621) |
| 0.0 | 0.4 | GO:0046886 | positive regulation of hormone biosynthetic process(GO:0046886) |
| 0.0 | 0.4 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 0.0 | 0.4 | GO:1904179 | positive regulation of adipose tissue development(GO:1904179) |
| 0.0 | 0.6 | GO:1902514 | regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514) |
| 0.0 | 0.8 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.0 | 0.1 | GO:0031056 | regulation of histone modification(GO:0031056) regulation of histone acetylation(GO:0035065) |
| 0.0 | 0.7 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
| 0.0 | 0.1 | GO:2000053 | regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053) |
| 0.0 | 0.2 | GO:0044805 | late nucleophagy(GO:0044805) |
| 0.0 | 0.5 | GO:0030043 | actin filament fragmentation(GO:0030043) |
| 0.0 | 0.2 | GO:0038172 | interleukin-33-mediated signaling pathway(GO:0038172) |
| 0.0 | 0.5 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 0.0 | 0.3 | GO:0001661 | conditioned taste aversion(GO:0001661) |
| 0.0 | 0.4 | GO:0070294 | renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294) |
| 0.0 | 0.1 | GO:0036093 | male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093) |
| 0.0 | 0.2 | GO:0035624 | receptor transactivation(GO:0035624) |
| 0.0 | 0.1 | GO:0019072 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 0.0 | 0.1 | GO:0019085 | early viral transcription(GO:0019085) |
| 0.0 | 0.1 | GO:1900222 | negative regulation of beta-amyloid clearance(GO:1900222) |
| 0.0 | 0.2 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
| 0.0 | 0.2 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
| 0.0 | 0.9 | GO:0042744 | hydrogen peroxide catabolic process(GO:0042744) |
| 0.0 | 0.2 | GO:0043418 | homocysteine catabolic process(GO:0043418) |
| 0.0 | 0.4 | GO:0014877 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.0 | 0.1 | GO:0072356 | chromosome passenger complex localization to kinetochore(GO:0072356) |
| 0.0 | 0.0 | GO:0015798 | myo-inositol transport(GO:0015798) |
| 0.0 | 0.2 | GO:0035494 | SNARE complex disassembly(GO:0035494) |
| 0.0 | 0.2 | GO:1904885 | beta-catenin destruction complex assembly(GO:1904885) |
| 0.0 | 0.3 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.0 | 0.3 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.0 | 0.1 | GO:0097327 | response to antineoplastic agent(GO:0097327) negative regulation of synaptic vesicle exocytosis(GO:2000301) |
| 0.0 | 0.1 | GO:0035526 | retrograde transport, plasma membrane to Golgi(GO:0035526) |
| 0.0 | 0.5 | GO:1904886 | beta-catenin destruction complex disassembly(GO:1904886) |
| 0.0 | 0.1 | GO:1902309 | regulation of peptidyl-serine dephosphorylation(GO:1902308) negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 0.0 | 0.2 | GO:0045824 | negative regulation of innate immune response(GO:0045824) |
| 0.0 | 0.2 | GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) |
| 0.0 | 0.1 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
| 0.0 | 0.4 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
| 0.0 | 0.4 | GO:0072189 | ureter development(GO:0072189) |
| 0.0 | 0.1 | GO:0090625 | mRNA cleavage involved in gene silencing by siRNA(GO:0090625) |
| 0.0 | 0.1 | GO:0090296 | regulation of mitochondrial DNA replication(GO:0090296) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) |
| 0.0 | 0.1 | GO:1900239 | phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239) |
| 0.0 | 0.0 | GO:0010716 | negative regulation of extracellular matrix disassembly(GO:0010716) |
| 0.0 | 0.2 | GO:1902019 | regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019) |
| 0.0 | 0.1 | GO:0001544 | initiation of primordial ovarian follicle growth(GO:0001544) |
| 0.0 | 0.1 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) |
| 0.0 | 0.1 | GO:1903778 | protein localization to vacuolar membrane(GO:1903778) |
| 0.0 | 0.1 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
| 0.0 | 0.4 | GO:0036148 | phosphatidylglycerol acyl-chain remodeling(GO:0036148) |
| 0.0 | 0.6 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
| 0.0 | 0.8 | GO:0042994 | cytoplasmic sequestering of transcription factor(GO:0042994) |
| 0.0 | 0.1 | GO:0032877 | positive regulation of DNA endoreduplication(GO:0032877) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930) |
| 0.0 | 0.1 | GO:0043323 | regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323) |
| 0.0 | 0.2 | GO:1902219 | negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219) |
| 0.0 | 0.2 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.0 | 0.1 | GO:1903028 | positive regulation of opsonization(GO:1903028) |
| 0.0 | 0.3 | GO:0043401 | steroid hormone mediated signaling pathway(GO:0043401) |
| 0.0 | 0.6 | GO:1904659 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.0 | 0.1 | GO:0048549 | positive regulation of pinocytosis(GO:0048549) |
| 0.0 | 0.4 | GO:0032464 | positive regulation of protein homooligomerization(GO:0032464) |
| 0.0 | 0.1 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
| 0.0 | 0.3 | GO:0036295 | cellular response to increased oxygen levels(GO:0036295) |
| 0.0 | 0.1 | GO:0060011 | Sertoli cell proliferation(GO:0060011) |
| 0.0 | 0.2 | GO:0086042 | cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) |
| 0.0 | 0.8 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 0.1 | GO:0048664 | neuron fate determination(GO:0048664) epithelial-mesenchymal cell signaling(GO:0060684) |
| 0.0 | 0.0 | GO:0002372 | myeloid dendritic cell cytokine production(GO:0002372) |
| 0.0 | 0.9 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.0 | 0.3 | GO:0051901 | positive regulation of mitochondrial depolarization(GO:0051901) |
| 0.0 | 0.1 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.0 | 0.3 | GO:0036152 | phosphatidylethanolamine acyl-chain remodeling(GO:0036152) |
| 0.0 | 0.3 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.0 | 0.1 | GO:0045829 | negative regulation of isotype switching(GO:0045829) |
| 0.0 | 0.0 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
| 0.0 | 0.9 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.0 | 0.3 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
| 0.0 | 0.3 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 0.1 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.0 | 0.0 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
| 0.0 | 0.5 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
| 0.0 | 0.2 | GO:0060385 | axonogenesis involved in innervation(GO:0060385) |
| 0.0 | 0.1 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.0 | 0.2 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.0 | 0.1 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
| 0.0 | 0.5 | GO:0035728 | response to hepatocyte growth factor(GO:0035728) |
| 0.0 | 0.1 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.0 | 0.1 | GO:0035973 | aggrephagy(GO:0035973) |
| 0.0 | 0.1 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
| 0.0 | 0.2 | GO:0001514 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.0 | 1.1 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.0 | 0.3 | GO:0006853 | carnitine shuttle(GO:0006853) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 1.6 | GO:0005584 | collagen type I trimer(GO:0005584) |
| 0.2 | 1.5 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.2 | 0.6 | GO:0042272 | nuclear RNA export factor complex(GO:0042272) |
| 0.1 | 0.5 | GO:0031251 | PAN complex(GO:0031251) |
| 0.1 | 1.5 | GO:0032009 | early phagosome(GO:0032009) |
| 0.1 | 0.3 | GO:0034677 | integrin alpha7-beta1 complex(GO:0034677) |
| 0.1 | 0.4 | GO:0030934 | anchoring collagen complex(GO:0030934) |
| 0.1 | 0.3 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.1 | 0.1 | GO:0098651 | basement membrane collagen trimer(GO:0098651) |
| 0.1 | 0.3 | GO:0070931 | Golgi-associated vesicle lumen(GO:0070931) |
| 0.1 | 1.2 | GO:0042627 | chylomicron(GO:0042627) |
| 0.1 | 0.7 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.0 | 0.1 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 0.0 | 0.2 | GO:0031905 | early endosome lumen(GO:0031905) |
| 0.0 | 0.5 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.0 | 0.4 | GO:0005683 | U7 snRNP(GO:0005683) |
| 0.0 | 0.7 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.0 | 0.4 | GO:0005583 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.0 | 0.9 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.0 | 0.1 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.0 | 0.1 | GO:0097635 | extrinsic component of autophagosome membrane(GO:0097635) |
| 0.0 | 0.1 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.0 | 0.3 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.0 | 0.2 | GO:0070695 | FHF complex(GO:0070695) |
| 0.0 | 0.3 | GO:0030868 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 0.0 | 0.4 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.0 | 0.4 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.0 | 0.5 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 0.0 | 0.1 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.0 | 0.1 | GO:0097629 | extrinsic component of omegasome membrane(GO:0097629) |
| 0.0 | 1.4 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.4 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 0.3 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.0 | 0.3 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.0 | 0.2 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 0.1 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 0.0 | 0.4 | GO:0043220 | Schmidt-Lanterman incisure(GO:0043220) |
| 0.0 | 0.4 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.0 | 0.2 | GO:0031462 | Cul2-RING ubiquitin ligase complex(GO:0031462) |
| 0.0 | 0.1 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.0 | 0.1 | GO:1990851 | Wnt-Frizzled-LRP5/6 complex(GO:1990851) |
| 0.0 | 0.4 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.0 | 0.2 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.0 | 0.4 | GO:0031011 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 0.0 | 0.2 | GO:0061673 | mitotic spindle astral microtubule(GO:0061673) |
| 0.0 | 0.3 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.0 | 1.2 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.1 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 0.0 | 0.5 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.0 | 0.4 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.0 | 0.4 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.0 | 1.9 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.0 | 0.3 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.0 | 1.6 | GO:0005776 | autophagosome(GO:0005776) |
| 0.0 | 1.2 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.0 | 0.3 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 0.2 | GO:0010369 | chromocenter(GO:0010369) |
| 0.0 | 0.1 | GO:0017119 | Golgi transport complex(GO:0017119) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.6 | GO:0004087 | carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
| 0.3 | 1.2 | GO:0017129 | triglyceride binding(GO:0017129) |
| 0.3 | 0.9 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 0.2 | 0.7 | GO:0047389 | glycerophosphocholine phosphodiesterase activity(GO:0047389) |
| 0.2 | 0.8 | GO:0005019 | platelet-derived growth factor beta-receptor activity(GO:0005019) |
| 0.2 | 0.9 | GO:0005152 | interleukin-1 receptor antagonist activity(GO:0005152) |
| 0.2 | 0.7 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.2 | 2.4 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.2 | 0.6 | GO:0033300 | dehydroascorbic acid transporter activity(GO:0033300) |
| 0.2 | 1.4 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 0.1 | 1.2 | GO:0043426 | MRF binding(GO:0043426) |
| 0.1 | 0.7 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.1 | 1.0 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 0.1 | 0.3 | GO:0004947 | bradykinin receptor activity(GO:0004947) |
| 0.1 | 1.4 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.1 | 0.7 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.1 | 0.4 | GO:0071209 | U7 snRNA binding(GO:0071209) |
| 0.1 | 0.2 | GO:0045155 | electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155) |
| 0.1 | 0.5 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 0.1 | 0.7 | GO:0001025 | RNA polymerase III transcription factor binding(GO:0001025) |
| 0.1 | 0.6 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
| 0.1 | 0.3 | GO:0044378 | non-sequence-specific DNA binding, bending(GO:0044378) |
| 0.1 | 0.5 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.1 | 0.2 | GO:0004366 | glycerol-3-phosphate O-acyltransferase activity(GO:0004366) |
| 0.1 | 0.2 | GO:0036487 | nitric-oxide synthase inhibitor activity(GO:0036487) |
| 0.1 | 0.4 | GO:0031750 | D3 dopamine receptor binding(GO:0031750) |
| 0.1 | 0.2 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
| 0.1 | 0.7 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.1 | 0.2 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 0.1 | 0.3 | GO:0008798 | beta-aspartyl-peptidase activity(GO:0008798) |
| 0.0 | 0.6 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.0 | 0.3 | GO:0098639 | collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 0.0 | 0.3 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.0 | 1.2 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 0.1 | GO:0015439 | heme-transporting ATPase activity(GO:0015439) |
| 0.0 | 1.1 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.0 | 0.4 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
| 0.0 | 0.6 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.0 | 0.6 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.0 | 0.1 | GO:0030350 | iron-responsive element binding(GO:0030350) |
| 0.0 | 0.3 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.0 | 0.5 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.0 | 0.2 | GO:0002114 | interleukin-33 receptor activity(GO:0002114) |
| 0.0 | 0.8 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.0 | 0.3 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.0 | 0.2 | GO:0008457 | beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256) |
| 0.0 | 0.3 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) ER retention sequence binding(GO:0046923) |
| 0.0 | 0.1 | GO:0051800 | phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800) |
| 0.0 | 0.1 | GO:0070326 | very-low-density lipoprotein particle receptor binding(GO:0070326) |
| 0.0 | 0.4 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 0.0 | 0.1 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
| 0.0 | 0.1 | GO:0031752 | D5 dopamine receptor binding(GO:0031752) |
| 0.0 | 0.1 | GO:0031896 | vasopressin receptor binding(GO:0031893) V2 vasopressin receptor binding(GO:0031896) |
| 0.0 | 0.4 | GO:0047144 | 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144) |
| 0.0 | 0.3 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.0 | 0.1 | GO:0005169 | neurotrophin TRKB receptor binding(GO:0005169) |
| 0.0 | 0.2 | GO:0004800 | thyroxine 5'-deiodinase activity(GO:0004800) |
| 0.0 | 0.6 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.0 | 0.1 | GO:1904928 | coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928) |
| 0.0 | 0.2 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.0 | 0.4 | GO:0042301 | phosphate ion binding(GO:0042301) |
| 0.0 | 0.2 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.0 | 0.3 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.0 | 0.1 | GO:0044736 | acid-sensing ion channel activity(GO:0044736) |
| 0.0 | 0.1 | GO:0032427 | GBD domain binding(GO:0032427) |
| 0.0 | 0.2 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 0.1 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
| 0.0 | 0.3 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.0 | 0.3 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.0 | 0.2 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.0 | 0.3 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
| 0.0 | 0.3 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.0 | 1.0 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.0 | 0.6 | GO:0031690 | adrenergic receptor binding(GO:0031690) |
| 0.0 | 0.1 | GO:0098811 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
| 0.0 | 0.9 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.0 | 0.2 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.0 | 0.4 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
| 0.0 | 0.3 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 0.0 | 0.1 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 0.0 | 0.1 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.0 | 0.3 | GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) |
| 0.0 | 0.3 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.0 | 0.3 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.0 | 0.3 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
| 0.0 | 0.0 | GO:0004119 | cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) |
| 0.0 | 0.3 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 1.3 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 0.1 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 0.0 | 0.4 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.0 | 0.2 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.0 | 0.5 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.0 | 0.1 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 0.0 | 0.8 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.0 | 0.1 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 0.0 | 0.0 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
| 0.0 | 0.9 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.0 | GO:0031626 | beta-endorphin binding(GO:0031626) |
| 0.0 | 0.5 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.0 | 0.1 | GO:0008565 | protein transporter activity(GO:0008565) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.2 | PID_SYNDECAN_1_PATHWAY | Syndecan-1-mediated signaling events |
| 0.0 | 1.1 | PID_S1P_S1P1_PATHWAY | S1P1 pathway |
| 0.0 | 0.7 | PID_RANBP2_PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.0 | 1.1 | PID_PRL_SIGNALING_EVENTS_PATHWAY | Signaling events mediated by PRL |
| 0.0 | 0.2 | PID_ER_NONGENOMIC_PATHWAY | Plasma membrane estrogen receptor signaling |
| 0.0 | 0.2 | PID_S1P_S1P4_PATHWAY | S1P4 pathway |
| 0.0 | 0.5 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 1.9 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 1.3 | PID_AURORA_B_PATHWAY | Aurora B signaling |
| 0.0 | 0.4 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 0.4 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.9 | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.0 | 2.8 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 1.1 | REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.0 | 0.7 | REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.0 | 0.7 | REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 1.2 | REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.0 | 0.9 | REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.0 | 0.4 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.0 | 0.6 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.0 | 0.9 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 0.1 | REACTOME_ARMS_MEDIATED_ACTIVATION | Genes involved in ARMS-mediated activation |
| 0.0 | 0.2 | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.0 | 0.4 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PG | Genes involved in Acyl chain remodelling of PG |
| 0.0 | 0.4 | REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.0 | 1.3 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 0.5 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 0.5 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.0 | 0.5 | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.0 | 0.6 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.0 | 0.2 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.0 | 0.5 | REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.0 | 0.5 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.0 | 0.1 | REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR | Genes involved in Thromboxane signalling through TP receptor |
| 0.0 | 0.3 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.0 | 0.3 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
| 0.0 | 0.7 | REACTOME_GLYCOSPHINGOLIPID_METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.0 | 0.2 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.0 | 0.3 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.0 | 0.4 | REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR | Genes involved in Signaling by constitutively active EGFR |
