Motif ID: ACAUUCA

Z-value: 1.308


Mature miRNA associated with seed ACAUUCA:

NamemiRBase Accession
hsa-miR-181a-5p MIMAT0000256
hsa-miR-181b-5p MIMAT0000257
hsa-miR-181c-5p MIMAT0000258
hsa-miR-181d-5p MIMAT0002821
hsa-miR-4262 MIMAT0016894



Activity profile for motif ACAUUCA.

activity profile for motif ACAUUCA


Sorted Z-values histogram for motif ACAUUCA

Sorted Z-values for motif ACAUUCA



Network of associatons between targets according to the STRING database.



First level regulatory network of ACAUUCA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_86046433 0.630 ENST00000451137.2
CYR61
cysteine-rich, angiogenic inducer, 61
chr2_+_36582857 0.602 ENST00000280527.2
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr5_+_173315283 0.521 ENST00000265085.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr1_+_27320176 0.516 ENST00000522111.2
TRNP1
TMF1-regulated nuclear protein 1
chr10_-_15210666 0.493 ENST00000378165.4
NMT2
N-myristoyltransferase 2
chr8_-_67525473 0.490 ENST00000522677.3
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr5_-_132073210 0.437 ENST00000378735.1
ENST00000378746.4
KIF3A

kinesin family member 3A

chr4_-_125633876 0.434 ENST00000504087.1
ENST00000515641.1
ANKRD50

ankyrin repeat domain 50

chr12_+_68042495 0.417 ENST00000344096.3
DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr14_-_95786200 0.409 ENST00000298912.4
CLMN
calmin (calponin-like, transmembrane)
chr10_-_52008313 0.409 ENST00000329428.6
ENST00000395526.4
ENST00000447815.1
ASAH2


N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2


chr4_+_39046615 0.409 ENST00000261425.3
ENST00000508137.2
KLHL5

kelch-like family member 5

chr12_-_80084862 0.401 ENST00000328827.4
PAWR
PRKC, apoptosis, WT1, regulator
chr3_+_150804676 0.400 ENST00000474524.1
ENST00000273432.4
MED12L

mediator complex subunit 12-like

chr1_-_225840747 0.398 ENST00000366843.2
ENST00000366844.3
ENAH

enabled homolog (Drosophila)

chr17_-_76356148 0.398 ENST00000587578.1
ENST00000330871.2
SOCS3

suppressor of cytokine signaling 3

chr2_+_200775971 0.378 ENST00000319974.5
C2orf69
chromosome 2 open reading frame 69
chr7_-_27224795 0.374 ENST00000006015.3
HOXA11
homeobox A11
chr1_-_120612240 0.373 ENST00000256646.2
NOTCH2
notch 2
chr4_+_6911171 0.368 ENST00000448507.1
TBC1D14
TBC1 domain family, member 14
chr11_+_118307179 0.365 ENST00000534358.1
ENST00000531904.2
ENST00000389506.5
ENST00000354520.4
KMT2A



lysine (K)-specific methyltransferase 2A



chr5_-_141704566 0.361 ENST00000344120.4
ENST00000434127.2
SPRY4

sprouty homolog 4 (Drosophila)

chrX_-_77395186 0.358 ENST00000341864.5
TAF9B
TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
chr2_-_64881018 0.357 ENST00000313349.3
SERTAD2
SERTA domain containing 2
chr1_+_164528866 0.357 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr5_-_137368708 0.356 ENST00000033079.3
FAM13B
family with sequence similarity 13, member B
chr12_-_109125285 0.350 ENST00000552871.1
ENST00000261401.3
CORO1C

coronin, actin binding protein, 1C

chr7_-_95225768 0.339 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr3_+_187930719 0.333 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr12_-_22697343 0.304 ENST00000446597.1
ENST00000536386.1
ENST00000396028.2
ENST00000545552.1
ENST00000544930.1
ENST00000333957.4
C2CD5





C2 calcium-dependent domain containing 5





chr13_+_98605902 0.300 ENST00000460070.1
ENST00000481455.1
ENST00000261574.5
ENST00000493281.1
ENST00000463157.1
ENST00000471898.1
ENST00000489058.1
ENST00000481689.1
IPO5







importin 5







chr4_-_114900831 0.288 ENST00000315366.7
ARSJ
arylsulfatase family, member J
chr18_-_12377283 0.287 ENST00000269143.3
AFG3L2
AFG3-like AAA ATPase 2
chr11_+_32914579 0.287 ENST00000399302.2
QSER1
glutamine and serine rich 1
chr16_-_87525651 0.285 ENST00000268616.4
ZCCHC14
zinc finger, CCHC domain containing 14
chr5_+_68462837 0.282 ENST00000256442.5
CCNB1
cyclin B1
chr2_-_225450013 0.279 ENST00000264414.4
CUL3
cullin 3
chrX_-_18372792 0.276 ENST00000251900.4
SCML2
sex comb on midleg-like 2 (Drosophila)
chr3_-_195270162 0.273 ENST00000438848.1
ENST00000328432.3
PPP1R2

protein phosphatase 1, regulatory (inhibitor) subunit 2

chr18_-_12657988 0.273 ENST00000410092.3
ENST00000409402.4
SPIRE1

spire-type actin nucleation factor 1

chr3_-_179169330 0.268 ENST00000232564.3
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chrX_-_130037198 0.268 ENST00000370935.1
ENST00000338144.3
ENST00000394363.1
ENOX2


ecto-NOX disulfide-thiol exchanger 2


chr6_-_136610911 0.265 ENST00000530767.1
ENST00000527759.1
ENST00000527536.1
ENST00000529826.1
ENST00000531224.1
ENST00000353331.4
BCLAF1





BCL2-associated transcription factor 1





chr16_+_50187556 0.264 ENST00000561678.1
ENST00000357464.3
PAPD5

PAP associated domain containing 5

chr2_+_191273052 0.263 ENST00000417958.1
ENST00000432036.1
ENST00000392328.1
MFSD6


major facilitator superfamily domain containing 6


chr5_+_65018017 0.261 ENST00000380985.5
ENST00000502464.1
NLN

neurolysin (metallopeptidase M3 family)

chr2_+_74881355 0.261 ENST00000357877.2
SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr10_+_70480963 0.260 ENST00000265872.6
ENST00000535016.1
ENST00000538031.1
ENST00000543719.1
ENST00000539539.1
ENST00000543225.1
ENST00000536012.1
ENST00000494903.2
CCAR1







cell division cycle and apoptosis regulator 1







chr2_+_153191706 0.258 ENST00000288670.9
FMNL2
formin-like 2
chr18_+_18943554 0.257 ENST00000580732.2
GREB1L
growth regulation by estrogen in breast cancer-like
chr17_+_65821780 0.252 ENST00000321892.4
ENST00000335221.5
ENST00000306378.6
BPTF


bromodomain PHD finger transcription factor


chr5_+_102455853 0.252 ENST00000515845.1
ENST00000321521.9
ENST00000507921.1
PPIP5K2


diphosphoinositol pentakisphosphate kinase 2


chr20_-_50159198 0.248 ENST00000371564.3
ENST00000396009.3
ENST00000610033.1
NFATC2


nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2


chr19_-_36909528 0.247 ENST00000392161.3
ENST00000392171.1
ZFP82

ZFP82 zinc finger protein

chr1_-_85156216 0.247 ENST00000342203.3
ENST00000370612.4
SSX2IP

synovial sarcoma, X breakpoint 2 interacting protein

chr9_-_3525968 0.244 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
RFX3


regulatory factor X, 3 (influences HLA class II expression)


chr2_-_208030647 0.239 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr1_+_210406121 0.239 ENST00000367012.3
SERTAD4
SERTA domain containing 4
chr4_+_48343339 0.238 ENST00000264313.6
SLAIN2
SLAIN motif family, member 2
chr3_-_192635943 0.235 ENST00000392452.2
MB21D2
Mab-21 domain containing 2
chr15_+_79724858 0.230 ENST00000305428.3
KIAA1024
KIAA1024
chr8_+_11141925 0.229 ENST00000221086.3
MTMR9
myotubularin related protein 9
chr6_-_110500905 0.226 ENST00000392587.2
WASF1
WAS protein family, member 1
chr11_-_85780086 0.225 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
PICALM


phosphatidylinositol binding clathrin assembly protein


chr3_+_152017181 0.224 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
MBNL1



muscleblind-like splicing regulator 1



chr14_+_100259666 0.223 ENST00000262233.6
ENST00000334192.4
EML1

echinoderm microtubule associated protein like 1

chr16_-_46865047 0.222 ENST00000394806.2
C16orf87
chromosome 16 open reading frame 87
chr6_-_90062543 0.219 ENST00000435041.2
UBE2J1
ubiquitin-conjugating enzyme E2, J1
chr7_+_140774032 0.217 ENST00000565468.1
TMEM178B
transmembrane protein 178B
chr7_+_97736197 0.217 ENST00000297293.5
LMTK2
lemur tyrosine kinase 2
chr12_-_56848426 0.216 ENST00000257979.4
MIP
major intrinsic protein of lens fiber
chr3_-_195163803 0.215 ENST00000326793.6
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr11_-_46940074 0.215 ENST00000378623.1
ENST00000534404.1
LRP4

low density lipoprotein receptor-related protein 4

chr10_+_60144782 0.215 ENST00000487519.1
TFAM
transcription factor A, mitochondrial
chr11_+_107879459 0.214 ENST00000393094.2
CUL5
cullin 5
chr4_+_37892682 0.213 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1


TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1


chr3_+_32147997 0.213 ENST00000282541.5
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr5_+_172068232 0.213 ENST00000520919.1
ENST00000522853.1
ENST00000369800.5
NEURL1B


neuralized E3 ubiquitin protein ligase 1B


chr1_+_93811438 0.212 ENST00000370272.4
ENST00000370267.1
DR1

down-regulator of transcription 1, TBP-binding (negative cofactor 2)

chr1_-_38325256 0.211 ENST00000373036.4
MTF1
metal-regulatory transcription factor 1
chr2_-_152684977 0.210 ENST00000428992.2
ENST00000295087.8
ARL5A

ADP-ribosylation factor-like 5A

chr8_-_91658303 0.210 ENST00000458549.2
TMEM64
transmembrane protein 64
chr4_+_99916765 0.209 ENST00000296411.6
METAP1
methionyl aminopeptidase 1
chr7_-_27135591 0.205 ENST00000343060.4
ENST00000355633.5
HOXA1

homeobox A1

chr22_+_24666763 0.205 ENST00000437398.1
ENST00000421374.1
ENST00000314328.9
ENST00000541492.1
SPECC1L



sperm antigen with calponin homology and coiled-coil domains 1-like



chrX_+_153665248 0.204 ENST00000447750.2
GDI1
GDP dissociation inhibitor 1
chr1_-_205719295 0.201 ENST00000367142.4
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr11_-_128392085 0.201 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
ETS1




v-ets avian erythroblastosis virus E26 oncogene homolog 1




chr16_+_69599861 0.199 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr8_-_18871159 0.199 ENST00000327040.8
ENST00000440756.2
PSD3

pleckstrin and Sec7 domain containing 3

chr14_+_67707826 0.199 ENST00000261681.4
MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr9_-_74980113 0.198 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
ZFAND5


zinc finger, AN1-type domain 5


chr4_+_7045042 0.198 ENST00000310074.7
ENST00000512388.1
TADA2B

transcriptional adaptor 2B

chrX_+_122993827 0.197 ENST00000371199.3
XIAP
X-linked inhibitor of apoptosis
chr5_+_145826867 0.196 ENST00000296702.5
ENST00000394421.2
TCERG1

transcription elongation regulator 1

chr12_-_118498958 0.196 ENST00000315436.3
WSB2
WD repeat and SOCS box containing 2
chr7_-_121036337 0.193 ENST00000426156.1
ENST00000359943.3
ENST00000412653.1
FAM3C


family with sequence similarity 3, member C


chr15_+_45879321 0.193 ENST00000220531.3
ENST00000567461.1
BLOC1S6

biogenesis of lysosomal organelles complex-1, subunit 6, pallidin

chr1_+_171454659 0.193 ENST00000367742.3
ENST00000338920.4
PRRC2C

proline-rich coiled-coil 2C

chr7_-_75988321 0.193 ENST00000307630.3
YWHAG
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
chr2_+_32582086 0.192 ENST00000421745.2
BIRC6
baculoviral IAP repeat containing 6
chr13_-_77601282 0.192 ENST00000355619.5
FBXL3
F-box and leucine-rich repeat protein 3
chr12_+_65563329 0.192 ENST00000308330.2
LEMD3
LEM domain containing 3
chr8_-_119634141 0.191 ENST00000409003.4
ENST00000526328.1
ENST00000314727.4
ENST00000526765.1
SAMD12



sterile alpha motif domain containing 12



chr13_-_110438914 0.189 ENST00000375856.3
IRS2
insulin receptor substrate 2
chr15_-_49447835 0.189 ENST00000388901.5
ENST00000299259.6
COPS2

COP9 signalosome subunit 2

chrX_+_40944871 0.188 ENST00000378308.2
ENST00000324545.8
USP9X

ubiquitin specific peptidase 9, X-linked

chr1_-_225615599 0.186 ENST00000421383.1
ENST00000272163.4
LBR

lamin B receptor

chr3_-_33481835 0.185 ENST00000283629.3
UBP1
upstream binding protein 1 (LBP-1a)
chr12_-_76425368 0.184 ENST00000602540.1
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr3_+_69812877 0.183 ENST00000457080.1
ENST00000328528.6
MITF

microphthalmia-associated transcription factor

chr1_+_244816237 0.183 ENST00000302550.11
DESI2
desumoylating isopeptidase 2
chr2_-_69870835 0.182 ENST00000409085.4
ENST00000406297.3
AAK1

AP2 associated kinase 1

chr17_-_18585541 0.179 ENST00000285274.5
ENST00000545289.1
ENST00000580145.1
ZNF286B


zinc finger protein 286B


chr7_+_100770328 0.179 ENST00000223095.4
ENST00000445463.2
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr4_+_77870856 0.178 ENST00000264893.6
ENST00000502584.1
ENST00000510641.1
SEPT11


septin 11


chrX_-_24045303 0.177 ENST00000328046.8
KLHL15
kelch-like family member 15
chr12_-_66524482 0.176 ENST00000446587.2
ENST00000266604.2
LLPH

LLP homolog, long-term synaptic facilitation (Aplysia)

chr12_+_32112340 0.176 ENST00000540924.1
ENST00000312561.4
KIAA1551

KIAA1551

chr2_-_206950781 0.175 ENST00000403263.1
INO80D
INO80 complex subunit D
chr15_+_77223960 0.173 ENST00000394885.3
RCN2
reticulocalbin 2, EF-hand calcium binding domain
chr14_-_64010046 0.171 ENST00000337537.3
PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr3_+_30648066 0.171 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr3_-_138553594 0.171 ENST00000477593.1
ENST00000483968.1
PIK3CB

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

chr5_-_79287060 0.170 ENST00000512560.1
ENST00000509852.1
ENST00000512528.1
MTX3


metaxin 3


chr7_+_65338230 0.169 ENST00000360768.3
VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr17_+_45727204 0.168 ENST00000290158.4
KPNB1
karyopherin (importin) beta 1
chr6_+_10556215 0.168 ENST00000316170.3
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr7_-_23510086 0.168 ENST00000258729.3
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr17_+_56160768 0.166 ENST00000579991.2
DYNLL2
dynein, light chain, LC8-type 2
chr1_+_200708671 0.165 ENST00000358823.2
CAMSAP2
calmodulin regulated spectrin-associated protein family, member 2
chr10_+_99344104 0.165 ENST00000555577.1
ENST00000370649.3
PI4K2A
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
Phosphatidylinositol 4-kinase type 2-alpha; Uncharacterized protein
chr4_+_159690218 0.163 ENST00000264433.6
FNIP2
folliculin interacting protein 2
chr4_-_174256276 0.163 ENST00000296503.5
HMGB2
high mobility group box 2
chr19_-_14629224 0.162 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr8_-_101965146 0.162 ENST00000395957.2
ENST00000395948.2
ENST00000457309.1
YWHAZ


tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta


chr12_-_76953284 0.162 ENST00000547544.1
ENST00000393249.2
OSBPL8

oxysterol binding protein-like 8

chr12_+_110719032 0.161 ENST00000395494.2
ATP2A2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr10_-_121356007 0.161 ENST00000369093.2
ENST00000436547.2
TIAL1

TIA1 cytotoxic granule-associated RNA binding protein-like 1

chr7_-_80548667 0.161 ENST00000265361.3
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr9_-_23821273 0.159 ENST00000380110.4
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr3_+_171758344 0.159 ENST00000336824.4
ENST00000423424.1
FNDC3B

fibronectin type III domain containing 3B

chr6_-_154831779 0.158 ENST00000607772.1
CNKSR3
CNKSR family member 3
chr21_-_40685477 0.158 ENST00000342449.3
BRWD1
bromodomain and WD repeat domain containing 1
chr22_-_39548627 0.157 ENST00000216133.5
CBX7
chromobox homolog 7
chr11_-_62314268 0.157 ENST00000257247.7
ENST00000531324.1
ENST00000378024.4
AHNAK


AHNAK nucleoprotein


chr14_+_103058948 0.157 ENST00000262241.6
RCOR1
REST corepressor 1
chr2_-_69614373 0.157 ENST00000361060.5
ENST00000357308.4
GFPT1

glutamine--fructose-6-phosphate transaminase 1

chr15_+_66679155 0.157 ENST00000307102.5
MAP2K1
mitogen-activated protein kinase kinase 1
chr9_-_138799070 0.157 ENST00000389532.4
ENST00000409386.3
CAMSAP1

calmodulin regulated spectrin-associated protein 1

chr1_-_28415204 0.157 ENST00000373871.3
EYA3
eyes absent homolog 3 (Drosophila)
chr8_+_37594130 0.156 ENST00000518526.1
ENST00000523887.1
ENST00000276461.5
ERLIN2


ER lipid raft associated 2


chr2_-_26101374 0.156 ENST00000435504.4
ASXL2
additional sex combs like 2 (Drosophila)
chr1_+_39456895 0.156 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
AKIRIN1


akirin 1


chr15_+_80351910 0.155 ENST00000261749.6
ENST00000561060.1
ZFAND6

zinc finger, AN1-type domain 6

chr5_+_137801160 0.153 ENST00000239938.4
EGR1
early growth response 1
chr5_-_89770582 0.152 ENST00000316610.6
MBLAC2
metallo-beta-lactamase domain containing 2
chr1_-_31538517 0.152 ENST00000440538.2
ENST00000423018.2
ENST00000424085.2
ENST00000426105.2
ENST00000257075.5
ENST00000373747.3
ENST00000525843.1
ENST00000373742.2
PUM1







pumilio RNA-binding family member 1







chr7_+_18535346 0.152 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
HDAC9


histone deacetylase 9


chrX_+_9431324 0.151 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X





transducin (beta)-like 1X-linked





chr12_-_12419703 0.151 ENST00000543091.1
ENST00000261349.4
LRP6

low density lipoprotein receptor-related protein 6

chr14_+_55034599 0.151 ENST00000392067.3
ENST00000357634.3
SAMD4A

sterile alpha motif domain containing 4A

chr3_+_45730733 0.150 ENST00000418611.1
ENST00000389061.5
SACM1L

SAC1 suppressor of actin mutations 1-like (yeast)

chr1_-_108742957 0.150 ENST00000565488.1
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr12_-_93835665 0.148 ENST00000552442.1
ENST00000550657.1
UBE2N

ubiquitin-conjugating enzyme E2N

chr20_+_35201857 0.148 ENST00000373874.2
TGIF2
TGFB-induced factor homeobox 2
chr2_+_179345173 0.148 ENST00000234453.5
PLEKHA3
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
chr16_-_73082274 0.148 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr12_-_46766577 0.147 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chr10_+_180987 0.146 ENST00000381591.1
ZMYND11
zinc finger, MYND-type containing 11
chr10_+_98592009 0.146 ENST00000540664.1
ENST00000371103.3
LCOR

ligand dependent nuclear receptor corepressor

chr16_+_53088885 0.146 ENST00000566029.1
ENST00000447540.1
CHD9

chromodomain helicase DNA binding protein 9

chr3_-_160283348 0.144 ENST00000334256.4
KPNA4
karyopherin alpha 4 (importin alpha 3)
chr1_+_198126093 0.141 ENST00000367385.4
ENST00000442588.1
ENST00000538004.1
NEK7


NIMA-related kinase 7


chr5_+_76011868 0.141 ENST00000319211.4
F2R
coagulation factor II (thrombin) receptor
chr3_+_186501336 0.141 ENST00000323963.5
ENST00000440191.2
ENST00000356531.5
EIF4A2


eukaryotic translation initiation factor 4A2


chr10_-_43133950 0.141 ENST00000359467.3
ZNF33B
zinc finger protein 33B
chr12_+_22778009 0.140 ENST00000266517.4
ENST00000335148.3
ETNK1

ethanolamine kinase 1

chr12_+_69004619 0.139 ENST00000250559.9
ENST00000393436.5
ENST00000425247.2
ENST00000489473.2
ENST00000422358.2
ENST00000541167.1
ENST00000538283.1
ENST00000341355.5
ENST00000537460.1
ENST00000450214.2
ENST00000545270.1
ENST00000538980.1
ENST00000542018.1
ENST00000543393.1
RAP1B













RAP1B, member of RAS oncogene family













chr12_+_121837844 0.138 ENST00000361234.5
RNF34
ring finger protein 34, E3 ubiquitin protein ligase
chr3_-_14166316 0.138 ENST00000396914.3
ENST00000295767.5
CHCHD4

coiled-coil-helix-coiled-coil-helix domain containing 4

chr16_+_55542910 0.138 ENST00000262134.5
LPCAT2
lysophosphatidylcholine acyltransferase 2
chr2_+_208394616 0.138 ENST00000432329.2
ENST00000353267.3
ENST00000445803.1
CREB1


cAMP responsive element binding protein 1


chr7_+_66205712 0.137 ENST00000442563.1
ENST00000450873.2
ENST00000284957.5
ENST00000451741.2
RABGEF1


KCTD7
RAB guanine nucleotide exchange factor (GEF) 1


potassium channel tetramerization domain containing 7
chr9_+_114659046 0.136 ENST00000374279.3
UGCG
UDP-glucose ceramide glucosyltransferase
chr2_+_242641442 0.135 ENST00000313552.6
ENST00000406941.1
ING5

inhibitor of growth family, member 5

chr11_+_108093839 0.135 ENST00000452508.2
ATM
ataxia telangiectasia mutated
chr3_-_182698381 0.133 ENST00000292782.4
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1
chr3_-_48885228 0.133 ENST00000454963.1
ENST00000296446.8
ENST00000419216.1
ENST00000265563.8
PRKAR2A



protein kinase, cAMP-dependent, regulatory, type II, alpha



chr4_-_100867864 0.133 ENST00000442697.2
DNAJB14
DnaJ (Hsp40) homolog, subfamily B, member 14
chr8_-_59572301 0.129 ENST00000038176.3
NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr10_-_60027642 0.129 ENST00000373935.3
IPMK
inositol polyphosphate multikinase
chrX_-_73834449 0.129 ENST00000332687.6
ENST00000349225.2
RLIM

ring finger protein, LIM domain interacting

chr13_-_39612176 0.129 ENST00000352251.3
ENST00000350125.3
PROSER1

proline and serine rich 1

chr5_-_131347306 0.129 ENST00000296869.4
ENST00000379249.3
ENST00000379272.2
ENST00000379264.2
ACSL6



acyl-CoA synthetase long-chain family member 6



chr10_+_31608054 0.127 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
ZEB1





zinc finger E-box binding homeobox 1





chr12_-_120806960 0.127 ENST00000257552.2
MSI1
musashi RNA-binding protein 1
chr12_+_122516626 0.127 ENST00000319080.7
MLXIP
MLX interacting protein
chr22_-_22221900 0.127 ENST00000215832.6
ENST00000398822.3
MAPK1

mitogen-activated protein kinase 1

chr15_-_51914996 0.127 ENST00000251076.5
DMXL2
Dmx-like 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 0.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.3 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.1 0.3 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.1 0.2 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.1 0.4 GO:2001038 regulation of cellular response to drug(GO:2001038)
0.1 0.2 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1 0.2 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.2 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.1 0.4 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 0.2 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.1 0.5 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.6 GO:0060591 apoptotic process involved in heart morphogenesis(GO:0003278) chondroblast differentiation(GO:0060591)
0.1 0.4 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 0.2 GO:0045210 FasL biosynthetic process(GO:0045210)
0.1 0.2 GO:0001300 chronological cell aging(GO:0001300)
0.1 0.2 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) endocardial cushion fusion(GO:0003274)
0.1 0.1 GO:1905007 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905007)
0.1 0.2 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.2 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.2 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720) cellular response to heparin(GO:0071504)
0.1 0.2 GO:2000053 canonical Wnt signaling pathway involved in neural crest cell differentiation(GO:0044335) Wnt signaling pathway involved in somitogenesis(GO:0090244) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.2 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.1 GO:0099541 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.0 0.1 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.1 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.1 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.0 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.1 GO:0015960 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966) cytosine metabolic process(GO:0019858)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.4 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.5 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.3 GO:0070649 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.1 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 0.1 GO:0021503 neural fold bending(GO:0021503)
0.0 0.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.1 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.0 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.3 GO:0043634 polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.0 0.5 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.2 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.6 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.2 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.1 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.0 0.3 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.4 GO:0060413 atrial septum morphogenesis(GO:0060413)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.1 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.1 GO:0051497 negative regulation of actin filament bundle assembly(GO:0032232) negative regulation of stress fiber assembly(GO:0051497)
0.0 0.3 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.2 GO:0030578 PML body organization(GO:0030578)
0.0 0.3 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.3 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.1 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.3 GO:0015866 ADP transport(GO:0015866)
0.0 0.2 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.0 GO:0051891 positive regulation of cardioblast differentiation(GO:0051891)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.2 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.5 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.0 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.2 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.1 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.2 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.0 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.1 GO:0032328 alanine transport(GO:0032328)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.2 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.1 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.0 GO:1990637 response to prolactin(GO:1990637)
0.0 0.4 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.0 GO:0046041 ITP metabolic process(GO:0046041)
0.0 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.0 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.3 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.7 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.3 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.3 GO:0050932 regulation of pigment cell differentiation(GO:0050932)
0.0 0.1 GO:0097709 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0 0.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.3 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.3 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.3 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.2 GO:0034657 GID complex(GO:0034657)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.2 GO:0035838 growing cell tip(GO:0035838)
0.0 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.1 GO:0002945 cyclin K-CDK12 complex(GO:0002944) cyclin K-CDK13 complex(GO:0002945)
0.0 0.6 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907)
0.0 0.3 GO:0005827 polar microtubule(GO:0005827)
0.0 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.3 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.3 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.2 0.5 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 0.4 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.2 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 0.2 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.1 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.3 GO:0031208 POZ domain binding(GO:0031208)
0.1 0.2 GO:0086039 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.1 0.2 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.0 0.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.4 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.0 0.2 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.1 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0 0.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.4 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.2 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.1 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.0 0.3 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.2 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.3 GO:0052744 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.0 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.0 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.2 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.5 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 1.2 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.5 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.5 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME_SOS_MEDIATED_SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.5 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.6 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.1 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.3 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)