Motif ID: AAUCUCU

Z-value: 0.174


Mature miRNA associated with seed AAUCUCU:

NamemiRBase Accession
hsa-miR-216b-5p MIMAT0004959



Activity profile for motif AAUCUCU.

activity profile for motif AAUCUCU


Sorted Z-values histogram for motif AAUCUCU

Sorted Z-values for motif AAUCUCU



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUCUCU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_12308447 0.154 ENST00000256186.2
MICALCL
MICAL C-terminal like
chr17_+_64298944 0.133 ENST00000413366.3
PRKCA
protein kinase C, alpha
chr18_-_22932080 0.117 ENST00000584787.1
ENST00000361524.3
ENST00000538137.2
ZNF521


zinc finger protein 521


chr10_-_104474128 0.091 ENST00000260746.5
ARL3
ADP-ribosylation factor-like 3
chr5_+_173315283 0.044 ENST00000265085.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr8_+_76452097 0.039 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr15_-_100258029 0.035 ENST00000378904.2
DKFZP779J2370
DKFZP779J2370
chr7_+_35840542 0.031 ENST00000435235.1
ENST00000399034.2
ENST00000350320.6
ENST00000469679.2
SEPT7



septin 7



chr6_+_114178512 0.025 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr13_-_31038370 0.022 ENST00000399489.1
ENST00000339872.4
HMGB1

high mobility group box 1

chr7_+_12250886 0.017 ENST00000444443.1
ENST00000396667.3
TMEM106B

transmembrane protein 106B

chr14_+_62037287 0.016 ENST00000556569.1
RP11-47I22.3
Uncharacterized protein
chr4_+_99916765 0.016 ENST00000296411.6
METAP1
methionyl aminopeptidase 1
chr9_-_20622478 0.014 ENST00000355930.6
ENST00000380338.4
MLLT3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr8_+_48920960 0.014 ENST00000523111.2
ENST00000523432.1
ENST00000521346.1
ENST00000517630.1
UBE2V2



ubiquitin-conjugating enzyme E2 variant 2



chr16_-_46723066 0.013 ENST00000299138.7
VPS35
vacuolar protein sorting 35 homolog (S. cerevisiae)
chrX_+_122993827 0.012 ENST00000371199.3
XIAP
X-linked inhibitor of apoptosis
chr6_+_42749759 0.011 ENST00000314073.5
GLTSCR1L
GLTSCR1-like
chr5_+_149109825 0.009 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
PPARGC1B


peroxisome proliferator-activated receptor gamma, coactivator 1 beta


chr1_+_2323260 0.009 ENST00000378518.1
ENST00000605895.1
ENST00000378513.3
ENST00000306256.9
ENST00000378512.1
RER1




retention in endoplasmic reticulum sorting receptor 1




chr16_+_67678818 0.008 ENST00000334583.6
RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr17_+_30677136 0.007 ENST00000394670.4
ENST00000321233.6
ENST00000394673.2
ENST00000341711.6
ENST00000579634.1
ENST00000580759.1
ENST00000342555.6
ENST00000577908.1
ENST00000394679.5
ENST00000582165.1
ZNF207









zinc finger protein 207









chr12_+_111471828 0.004 ENST00000261726.6
CUX2
cut-like homeobox 2
chr2_-_242212227 0.004 ENST00000427007.1
ENST00000458564.1
ENST00000452065.1
ENST00000427183.2
ENST00000426343.1
ENST00000422080.1
ENST00000449504.1
ENST00000449864.1
ENST00000391975.1
HDLBP








high density lipoprotein binding protein








chr10_-_120101804 0.002 ENST00000369183.4
ENST00000369172.4
FAM204A

family with sequence similarity 204, member A

chr8_-_114389353 0.001 ENST00000343508.3
CSMD3
CUB and Sushi multiple domains 3
chr1_-_153895377 0.001 ENST00000368655.4
GATAD2B
GATA zinc finger domain containing 2B
chr1_+_107683644 0.000 ENST00000370067.1
NTNG1
netrin G1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:2000705 histone H3-T6 phosphorylation(GO:0035408) dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine