Motif ID: AAGUGCU

Z-value: 0.922


Mature miRNA associated with seed AAGUGCU:

NamemiRBase Accession
hsa-miR-302a-3p MIMAT0000684
hsa-miR-302b-3p MIMAT0000715
hsa-miR-302c-3p.1 MIMAT0000717
hsa-miR-302d-3p MIMAT0000718
hsa-miR-302e MIMAT0005931
hsa-miR-372-3p MIMAT0000724
hsa-miR-373-3p MIMAT0000726
hsa-miR-520a-3p MIMAT0002834
hsa-miR-520b MIMAT0002843
hsa-miR-520c-3p MIMAT0002846
hsa-miR-520d-3p MIMAT0002856
hsa-miR-520e MIMAT0002825



Activity profile for motif AAGUGCU.

activity profile for motif AAGUGCU


Sorted Z-values histogram for motif AAGUGCU

Sorted Z-values for motif AAGUGCU



Network of associatons between targets according to the STRING database.



First level regulatory network of AAGUGCU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_75174180 1.211 ENST00000413830.1
EPGN
epithelial mitogen
chr10_+_28966271 1.073 ENST00000375533.3
BAMBI
BMP and activin membrane-bound inhibitor
chr10_+_54074033 1.052 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr1_-_16482554 0.939 ENST00000358432.5
EPHA2
EPH receptor A2
chr20_-_47894569 0.926 ENST00000371744.1
ENST00000371752.1
ENST00000396105.1
ZNFX1


zinc finger, NFX1-type containing 1


chr12_+_56915713 0.784 ENST00000262031.5
ENST00000552247.2
RBMS2

RNA binding motif, single stranded interacting protein 2

chr2_-_72375167 0.689 ENST00000001146.2
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr20_-_30795511 0.618 ENST00000246229.4
PLAGL2
pleiomorphic adenoma gene-like 2
chr1_-_38325256 0.614 ENST00000373036.4
MTF1
metal-regulatory transcription factor 1
chr6_+_126112001 0.610 ENST00000392477.2
NCOA7
nuclear receptor coactivator 7
chr8_-_67525473 0.609 ENST00000522677.3
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr2_+_70142189 0.576 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr14_-_23451845 0.573 ENST00000262713.2
AJUBA
ajuba LIM protein
chr13_+_49550015 0.572 ENST00000492622.2
FNDC3A
fibronectin type III domain containing 3A
chr9_+_5510492 0.533 ENST00000397745.2
PDCD1LG2
programmed cell death 1 ligand 2
chr9_-_16870704 0.531 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2



basonuclin 2



chr10_-_61469837 0.528 ENST00000395348.3
SLC16A9
solute carrier family 16, member 9
chr3_+_30648066 0.503 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr7_+_20370746 0.501 ENST00000222573.4
ITGB8
integrin, beta 8
chr22_-_30642728 0.465 ENST00000403987.3
LIF
leukemia inhibitory factor
chr8_-_134584152 0.457 ENST00000521180.1
ENST00000517668.1
ENST00000319914.5
ST3GAL1


ST3 beta-galactoside alpha-2,3-sialyltransferase 1


chr2_-_151344172 0.437 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3


Rho family GTPase 3


chr4_+_160188889 0.419 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr1_-_231560790 0.417 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr11_+_122526383 0.409 ENST00000284273.5
UBASH3B
ubiquitin associated and SH3 domain containing B
chr12_-_108154925 0.408 ENST00000228437.5
PRDM4
PR domain containing 4
chr1_-_149982624 0.404 ENST00000417191.1
ENST00000369135.4
OTUD7B

OTU domain containing 7B

chr5_+_56111361 0.400 ENST00000399503.3
MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr14_-_53619816 0.400 ENST00000323669.5
ENST00000395606.1
ENST00000357758.3
DDHD1


DDHD domain containing 1


chr4_-_125633876 0.392 ENST00000504087.1
ENST00000515641.1
ANKRD50

ankyrin repeat domain 50

chr9_-_130742792 0.389 ENST00000373095.1
FAM102A
family with sequence similarity 102, member A
chr3_+_150804676 0.379 ENST00000474524.1
ENST00000273432.4
MED12L

mediator complex subunit 12-like

chr7_-_5821314 0.376 ENST00000425013.2
ENST00000389902.3
RNF216

ring finger protein 216

chr1_-_113249948 0.374 ENST00000339083.7
ENST00000369642.3
RHOC

ras homolog family member C

chr9_+_82186872 0.366 ENST00000376544.3
ENST00000376520.4
TLE4

transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)

chr19_+_7459998 0.364 ENST00000319670.9
ENST00000599752.1
ARHGEF18

Rho/Rac guanine nucleotide exchange factor (GEF) 18

chr1_-_179198702 0.358 ENST00000502732.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr12_-_56652111 0.357 ENST00000267116.7
ANKRD52
ankyrin repeat domain 52
chr5_-_56247935 0.354 ENST00000381199.3
ENST00000381226.3
ENST00000381213.3
MIER3


mesoderm induction early response 1, family member 3


chr2_-_43453734 0.353 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr3_+_47324424 0.353 ENST00000437353.1
ENST00000232766.5
ENST00000455924.2
KLHL18


kelch-like family member 18


chr16_-_71758602 0.352 ENST00000568954.1
PHLPP2
PH domain and leucine rich repeat protein phosphatase 2
chr14_+_36295504 0.348 ENST00000216807.7
BRMS1L
breast cancer metastasis-suppressor 1-like
chr9_-_101017862 0.348 ENST00000375064.1
ENST00000342112.5
TBC1D2

TBC1 domain family, member 2

chr6_+_41040678 0.346 ENST00000341376.6
ENST00000353205.5
NFYA

nuclear transcription factor Y, alpha

chr1_-_53793584 0.341 ENST00000354412.3
ENST00000347547.2
ENST00000306052.6
LRP8


low density lipoprotein receptor-related protein 8, apolipoprotein e receptor


chr10_+_98741041 0.337 ENST00000286067.2
C10orf12
chromosome 10 open reading frame 12
chr17_+_73717516 0.335 ENST00000200181.3
ENST00000339591.3
ITGB4

integrin, beta 4

chr2_+_200775971 0.332 ENST00000319974.5
C2orf69
chromosome 2 open reading frame 69
chr5_-_141704566 0.329 ENST00000344120.4
ENST00000434127.2
SPRY4

sprouty homolog 4 (Drosophila)

chr6_+_149887377 0.325 ENST00000367419.5
GINM1
glycoprotein integral membrane 1
chr3_+_43328004 0.322 ENST00000454177.1
ENST00000429705.2
ENST00000296088.7
ENST00000437827.1
SNRK



SNF related kinase



chr1_+_28696111 0.322 ENST00000373839.3
PHACTR4
phosphatase and actin regulator 4
chr1_-_153931052 0.317 ENST00000368630.3
ENST00000368633.1
CRTC2

CREB regulated transcription coactivator 2

chr11_+_109964087 0.317 ENST00000278590.3
ZC3H12C
zinc finger CCCH-type containing 12C
chr12_+_68042495 0.313 ENST00000344096.3
DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr2_+_29338236 0.312 ENST00000320081.5
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr4_+_6271558 0.306 ENST00000503569.1
ENST00000226760.1
WFS1

Wolfram syndrome 1 (wolframin)

chr3_+_126707437 0.305 ENST00000393409.2
ENST00000251772.4
PLXNA1

plexin A1

chr5_-_114515734 0.303 ENST00000514154.1
ENST00000282369.3
TRIM36

tripartite motif containing 36

chr6_+_157802165 0.298 ENST00000414563.2
ENST00000359775.5
ZDHHC14

zinc finger, DHHC-type containing 14

chr3_+_137906109 0.297 ENST00000481646.1
ENST00000469044.1
ENST00000491704.1
ENST00000461600.1
ARMC8



armadillo repeat containing 8



chr3_+_58291965 0.297 ENST00000445193.3
ENST00000295959.5
ENST00000466547.1
RPP14


ribonuclease P/MRP 14kDa subunit


chr11_-_62314268 0.294 ENST00000257247.7
ENST00000531324.1
ENST00000378024.4
AHNAK


AHNAK nucleoprotein


chr6_-_108395907 0.288 ENST00000193322.3
OSTM1
osteopetrosis associated transmembrane protein 1
chr2_+_134877740 0.284 ENST00000409645.1
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr5_-_114880533 0.283 ENST00000274457.3
FEM1C
fem-1 homolog c (C. elegans)
chr16_-_47007545 0.282 ENST00000317089.5
DNAJA2
DnaJ (Hsp40) homolog, subfamily A, member 2
chr3_+_172468472 0.279 ENST00000232458.5
ENST00000392692.3
ECT2

epithelial cell transforming sequence 2 oncogene

chr12_+_72148614 0.272 ENST00000261263.3
RAB21
RAB21, member RAS oncogene family
chr9_-_37576226 0.269 ENST00000432825.2
FBXO10
F-box protein 10
chr1_-_235491462 0.269 ENST00000418304.1
ENST00000264183.3
ENST00000349213.3
ARID4B


AT rich interactive domain 4B (RBP1-like)


chr3_+_152017181 0.269 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
MBNL1



muscleblind-like splicing regulator 1



chr4_+_15004165 0.267 ENST00000538197.1
ENST00000541112.1
ENST00000442003.2
CPEB2


cytoplasmic polyadenylation element binding protein 2


chr1_+_162039558 0.263 ENST00000530878.1
ENST00000361897.5
NOS1AP

nitric oxide synthase 1 (neuronal) adaptor protein

chr4_-_41216619 0.263 ENST00000508676.1
ENST00000506352.1
ENST00000295974.8
APBB2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr12_-_96184533 0.261 ENST00000343702.4
ENST00000344911.4
NTN4

netrin 4

chr2_-_73340146 0.260 ENST00000258098.6
RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr1_-_150552006 0.260 ENST00000307940.3
ENST00000369026.2
MCL1

myeloid cell leukemia sequence 1 (BCL2-related)

chr8_+_28351707 0.258 ENST00000537916.1
ENST00000523546.1
ENST00000240093.3
FZD3


frizzled family receptor 3


chr1_-_85156216 0.257 ENST00000342203.3
ENST00000370612.4
SSX2IP

synovial sarcoma, X breakpoint 2 interacting protein

chr3_+_11314099 0.256 ENST00000446450.2
ENST00000354956.5
ENST00000354449.3
ENST00000419112.1
ATG7



autophagy related 7



chr2_+_150187020 0.254 ENST00000334166.4
LYPD6
LY6/PLAUR domain containing 6
chr20_+_43104508 0.253 ENST00000262605.4
ENST00000372904.3
TTPAL

tocopherol (alpha) transfer protein-like

chr7_-_105517021 0.252 ENST00000318724.4
ENST00000419735.3
ATXN7L1

ataxin 7-like 1

chr18_-_29264669 0.250 ENST00000306851.5
B4GALT6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr19_+_38397839 0.250 ENST00000222345.6
SIPA1L3
signal-induced proliferation-associated 1 like 3
chr12_+_27396901 0.250 ENST00000541191.1
ENST00000389032.3
STK38L

serine/threonine kinase 38 like

chr1_-_94703118 0.249 ENST00000260526.6
ENST00000370217.3
ARHGAP29

Rho GTPase activating protein 29

chr8_-_103876965 0.247 ENST00000337198.5
AZIN1
antizyme inhibitor 1
chr7_+_28452130 0.244 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr5_+_52285144 0.243 ENST00000296585.5
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr1_+_24069642 0.243 ENST00000418390.2
TCEB3
transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
chr1_+_32645269 0.242 ENST00000373610.3
TXLNA
taxilin alpha
chr3_-_48229846 0.238 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
CDC25A


cell division cycle 25A


chr6_+_33422343 0.236 ENST00000395064.2
ZBTB9
zinc finger and BTB domain containing 9
chr16_+_9185450 0.234 ENST00000327827.7
C16orf72
chromosome 16 open reading frame 72
chr11_-_78052923 0.230 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr1_-_25291475 0.228 ENST00000338888.3
ENST00000399916.1
RUNX3

runt-related transcription factor 3

chr4_-_76439596 0.227 ENST00000451788.1
ENST00000512706.1
RCHY1

ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase

chr15_+_96873921 0.223 ENST00000394166.3
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr7_-_152133059 0.220 ENST00000262189.6
ENST00000355193.2
KMT2C

lysine (K)-specific methyltransferase 2C

chr19_+_16222439 0.220 ENST00000300935.3
RAB8A
RAB8A, member RAS oncogene family
chr4_-_74124502 0.220 ENST00000358602.4
ENST00000330838.6
ENST00000561029.1
ANKRD17


ankyrin repeat domain 17


chr21_-_36260980 0.216 ENST00000344691.4
ENST00000358356.5
RUNX1

runt-related transcription factor 1

chr3_+_196466710 0.214 ENST00000327134.3
PAK2
p21 protein (Cdc42/Rac)-activated kinase 2
chr10_+_98592009 0.208 ENST00000540664.1
ENST00000371103.3
LCOR

ligand dependent nuclear receptor corepressor

chr6_+_1389989 0.205 ENST00000259806.1
FOXF2
forkhead box F2
chr10_+_3109695 0.200 ENST00000381125.4
PFKP
phosphofructokinase, platelet
chr3_-_50365607 0.196 ENST00000232496.4
TUSC2
tumor suppressor candidate 2
chr9_-_14314066 0.192 ENST00000397575.3
NFIB
nuclear factor I/B
chr21_-_43346790 0.191 ENST00000329623.7
C2CD2
C2 calcium-dependent domain containing 2
chr10_-_112064665 0.191 ENST00000369603.5
SMNDC1
survival motor neuron domain containing 1
chr2_+_179345173 0.189 ENST00000234453.5
PLEKHA3
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
chr18_+_32558208 0.185 ENST00000436190.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr6_-_116381918 0.185 ENST00000606080.1
FRK
fyn-related kinase
chr7_+_129074266 0.184 ENST00000249344.2
ENST00000435494.2
STRIP2

striatin interacting protein 2

chr19_-_4066890 0.183 ENST00000322357.4
ZBTB7A
zinc finger and BTB domain containing 7A
chr4_+_38665810 0.183 ENST00000261438.5
ENST00000514033.1
KLF3

Kruppel-like factor 3 (basic)

chr20_+_30865429 0.178 ENST00000375712.3
KIF3B
kinesin family member 3B
chr2_-_69870835 0.178 ENST00000409085.4
ENST00000406297.3
AAK1

AP2 associated kinase 1

chr4_-_79860506 0.177 ENST00000295462.3
ENST00000380645.4
ENST00000512733.1
PAQR3


progestin and adipoQ receptor family member III


chr4_+_48343339 0.176 ENST00000264313.6
SLAIN2
SLAIN motif family, member 2
chr8_-_41909496 0.175 ENST00000265713.2
ENST00000406337.1
ENST00000396930.3
ENST00000485568.1
ENST00000426524.1
KAT6A




K(lysine) acetyltransferase 6A




chr3_-_123603137 0.174 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
MYLK



myosin light chain kinase



chr12_+_69864129 0.172 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
FRS2









fibroblast growth factor receptor substrate 2









chr16_-_4323015 0.170 ENST00000204517.6
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr10_+_126490354 0.169 ENST00000298492.5
FAM175B
family with sequence similarity 175, member B
chr1_+_162467595 0.168 ENST00000538489.1
ENST00000489294.1
UHMK1

U2AF homology motif (UHM) kinase 1

chr5_+_179247759 0.165 ENST00000389805.4
ENST00000504627.1
ENST00000402874.3
ENST00000510187.1
SQSTM1



sequestosome 1



chr5_+_89770696 0.164 ENST00000504930.1
ENST00000514483.1
POLR3G

polymerase (RNA) III (DNA directed) polypeptide G (32kD)

chr5_+_98104978 0.162 ENST00000308234.7
RGMB
repulsive guidance molecule family member b
chr1_-_55680762 0.158 ENST00000407756.1
ENST00000294383.6
USP24

ubiquitin specific peptidase 24

chr6_+_45389893 0.158 ENST00000371432.3
RUNX2
runt-related transcription factor 2
chr1_+_12040238 0.157 ENST00000444836.1
ENST00000235329.5
MFN2

mitofusin 2

chr10_+_65281123 0.156 ENST00000298249.4
ENST00000373758.4
REEP3

receptor accessory protein 3

chr8_+_1772132 0.156 ENST00000349830.3
ENST00000520359.1
ENST00000518288.1
ENST00000398560.1
ARHGEF10



Rho guanine nucleotide exchange factor (GEF) 10



chr19_+_41768401 0.155 ENST00000352456.3
ENST00000595018.1
ENST00000597725.1
HNRNPUL1


heterogeneous nuclear ribonucleoprotein U-like 1


chr4_+_44680429 0.155 ENST00000281543.5
GUF1
GUF1 GTPase homolog (S. cerevisiae)
chr9_+_110045537 0.155 ENST00000358015.3
RAD23B
RAD23 homolog B (S. cerevisiae)
chr7_-_5463175 0.154 ENST00000399537.4
ENST00000430969.1
TNRC18

trinucleotide repeat containing 18

chr4_+_57774042 0.154 ENST00000309042.7
REST
RE1-silencing transcription factor
chr8_-_119634141 0.153 ENST00000409003.4
ENST00000526328.1
ENST00000314727.4
ENST00000526765.1
SAMD12



sterile alpha motif domain containing 12



chr11_+_69455855 0.152 ENST00000227507.2
ENST00000536559.1
CCND1

cyclin D1

chr11_+_58346584 0.150 ENST00000316059.6
ZFP91
ZFP91 zinc finger protein
chr2_-_68479614 0.149 ENST00000234310.3
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr16_-_48644061 0.149 ENST00000262384.3
N4BP1
NEDD4 binding protein 1
chr5_+_74807581 0.148 ENST00000241436.4
ENST00000352007.5
POLK

polymerase (DNA directed) kappa

chr16_-_3493528 0.147 ENST00000301744.4
ZNF597
zinc finger protein 597
chr2_-_197036289 0.142 ENST00000263955.4
STK17B
serine/threonine kinase 17b
chr17_+_38375574 0.139 ENST00000323571.4
ENST00000585043.1
ENST00000394103.3
ENST00000536600.1
WIPF2



WAS/WASL interacting protein family, member 2



chr5_-_148930960 0.138 ENST00000261798.5
ENST00000377843.2
CSNK1A1

casein kinase 1, alpha 1

chr20_+_36149602 0.138 ENST00000062104.2
ENST00000346199.2
NNAT

neuronatin

chr6_+_13615554 0.136 ENST00000451315.2
NOL7
nucleolar protein 7, 27kDa
chr12_+_8185288 0.136 ENST00000162391.3
FOXJ2
forkhead box J2
chr7_+_6144514 0.135 ENST00000306177.5
ENST00000465073.2
USP42

ubiquitin specific peptidase 42

chr11_+_32851487 0.135 ENST00000257836.3
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr16_-_71323271 0.135 ENST00000565850.1
ENST00000568910.1
ENST00000434935.2
ENST00000338099.5
CMTR2



cap methyltransferase 2



chr2_+_99953816 0.135 ENST00000289371.6
EIF5B
eukaryotic translation initiation factor 5B
chr15_+_38544476 0.134 ENST00000299084.4
SPRED1
sprouty-related, EVH1 domain containing 1
chr1_+_33207381 0.133 ENST00000401073.2
KIAA1522
KIAA1522
chr8_+_23386305 0.133 ENST00000519973.1
SLC25A37
solute carrier family 25 (mitochondrial iron transporter), member 37
chr22_+_33197683 0.132 ENST00000266085.6
TIMP3
TIMP metallopeptidase inhibitor 3
chr5_+_179159813 0.130 ENST00000292599.3
MAML1
mastermind-like 1 (Drosophila)
chr8_+_64081118 0.130 ENST00000539294.1
YTHDF3
YTH domain family, member 3
chr7_+_100136811 0.130 ENST00000300176.4
ENST00000262935.4
AGFG2

ArfGAP with FG repeats 2

chr3_-_50605077 0.129 ENST00000426034.1
ENST00000441239.1
C3orf18

chromosome 3 open reading frame 18

chr16_-_66785699 0.128 ENST00000258198.2
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr17_-_43568062 0.127 ENST00000421073.2
ENST00000584420.1
ENST00000589780.1
ENST00000430334.3
PLEKHM1



pleckstrin homology domain containing, family M (with RUN domain) member 1



chr3_-_197476560 0.127 ENST00000273582.5
KIAA0226
KIAA0226
chr16_+_29984962 0.126 ENST00000308893.4
TAOK2
TAO kinase 2
chr2_+_46524537 0.125 ENST00000263734.3
EPAS1
endothelial PAS domain protein 1
chr17_+_47074758 0.124 ENST00000290341.3
IGF2BP1
insulin-like growth factor 2 mRNA binding protein 1
chr8_-_101965146 0.122 ENST00000395957.2
ENST00000395948.2
ENST00000457309.1
YWHAZ


tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta


chr22_+_29279552 0.121 ENST00000544604.2
ZNRF3
zinc and ring finger 3
chr20_-_36156125 0.120 ENST00000397135.1
ENST00000397137.1
BLCAP

bladder cancer associated protein

chr10_+_102295616 0.120 ENST00000299163.6
HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr2_-_26101374 0.120 ENST00000435504.4
ASXL2
additional sex combs like 2 (Drosophila)
chr19_+_14017003 0.119 ENST00000318003.7
CC2D1A
coiled-coil and C2 domain containing 1A
chr2_+_170683942 0.119 ENST00000272793.5
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr9_+_36036430 0.118 ENST00000377966.3
RECK
reversion-inducing-cysteine-rich protein with kazal motifs
chr1_-_70671216 0.118 ENST00000370952.3
LRRC40
leucine rich repeat containing 40
chr15_-_41408409 0.117 ENST00000361937.3
INO80
INO80 complex subunit
chrX_+_48554986 0.116 ENST00000376687.3
ENST00000453214.2
SUV39H1

suppressor of variegation 3-9 homolog 1 (Drosophila)

chr15_-_78526942 0.115 ENST00000258873.4
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr16_+_19125252 0.114 ENST00000566735.1
ENST00000381440.3
ITPRIPL2

inositol 1,4,5-trisphosphate receptor interacting protein-like 2

chr4_+_74606223 0.110 ENST00000307407.3
ENST00000401931.1
IL8

interleukin 8

chr11_-_65430251 0.110 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
RELA






v-rel avian reticuloendotheliosis viral oncogene homolog A






chr2_-_103353277 0.110 ENST00000258436.5
MFSD9
major facilitator superfamily domain containing 9
chr3_+_10206545 0.109 ENST00000256458.4
IRAK2
interleukin-1 receptor-associated kinase 2
chr8_-_82024290 0.109 ENST00000220597.4
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr1_-_205601064 0.108 ENST00000357992.4
ENST00000289703.4
ELK4

ELK4, ETS-domain protein (SRF accessory protein 1)

chr1_+_36396677 0.108 ENST00000373191.4
ENST00000397828.2
AGO3

argonaute RISC catalytic component 3

chr3_+_42695176 0.107 ENST00000232974.6
ENST00000457842.3
ZBTB47

zinc finger and BTB domain containing 47

chr17_-_40306934 0.107 ENST00000550406.1
ENST00000547517.1
ENST00000393860.3
ENST00000346213.4
ENST00000592574.1
RAB5C



CTD-2132N18.3
RAB5C, member RAS oncogene family



Uncharacterized protein
chrX_+_16737718 0.107 ENST00000380155.3
SYAP1
synapse associated protein 1
chr14_-_68283291 0.106 ENST00000555452.1
ENST00000347230.4
ZFYVE26

zinc finger, FYVE domain containing 26

chr2_-_11484710 0.106 ENST00000315872.6
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chr2_+_149402553 0.105 ENST00000258484.6
ENST00000409654.1
EPC2

enhancer of polycomb homolog 2 (Drosophila)

chr13_+_39612442 0.104 ENST00000470258.1
ENST00000379600.3
NHLRC3

NHL repeat containing 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0100012 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) Wnt signaling pathway involved in somitogenesis(GO:0090244) regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.3 0.9 GO:0048320 axial mesoderm formation(GO:0048320)
0.3 0.3 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.2 0.7 GO:2001037 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.2 0.5 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.1 0.5 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.3 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.4 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.1 0.2 GO:0001743 optic placode formation(GO:0001743)
0.1 0.3 GO:1903762 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.1 0.3 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521)
0.1 0.2 GO:0033341 regulation of collagen binding(GO:0033341)
0.1 0.2 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 0.5 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.2 GO:0032618 interleukin-15 production(GO:0032618)
0.1 1.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.4 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.6 GO:0034378 chylomicron assembly(GO:0034378)
0.1 0.2 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 0.4 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.2 GO:0060849 radial pattern formation(GO:0009956) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 0.3 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.1 0.2 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 1.1 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.1 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.3 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.5 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0003162 atrioventricular node development(GO:0003162)
0.0 0.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.8 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.5 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.1 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.0 0.1 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.5 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.1 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.6 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.5 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.5 GO:0043586 tongue development(GO:0043586)
0.0 0.4 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:0072194 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587) kidney smooth muscle tissue development(GO:0072194)
0.0 0.1 GO:0043129 surfactant homeostasis(GO:0043129)
0.0 0.1 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.0 0.0 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.0 0.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.4 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.0 GO:0072720 response to dithiothreitol(GO:0072720)
0.0 0.1 GO:2001038 regulation of cellular response to drug(GO:2001038)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.5 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.2 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.3 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.4 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.0 0.3 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.3 GO:0071468 cellular response to acidic pH(GO:0071468)
0.0 0.0 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.4 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.2 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.2 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:0030262 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.0 GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.0 0.2 GO:0070141 response to UV-A(GO:0070141)
0.0 0.1 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.0 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.3 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 0.3 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.3 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0005873 plus-end kinesin complex(GO:0005873) kinesin II complex(GO:0016939)
0.0 0.2 GO:0044753 amphisome(GO:0044753)
0.0 0.2 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.1 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0097451 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.0 0.1 GO:0032302 MutSbeta complex(GO:0032302)
0.0 0.1 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.3 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.3 GO:0030681 multimeric ribonuclease P complex(GO:0030681)
0.0 0.1 GO:0002133 polycystin complex(GO:0002133)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.0 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.0 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 0.5 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.5 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.7 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 1.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.3 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 1.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.4 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 1.0 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.5 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.3 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.2 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939) alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0032181 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.0 0.3 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.0 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.4 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398) calcium-induced calcium release activity(GO:0048763)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 1.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.0 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.0 0.3 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0097493 S100 protein binding(GO:0044548) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.0 1.2 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 1.0 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.5 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.2 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.2 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.6 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.2 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.5 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.9 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.5 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.0 0.7 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.2 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.2 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.5 REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.5 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.2 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.1 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.5 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.7 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type