Motif ID: AAGGCAC
Z-value: 1.290
Mature miRNA associated with seed AAGGCAC:
| Name | miRBase Accession |
|---|---|
| hsa-miR-124-3p.1 | MIMAT0000422 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.2 | GO:1903966 | monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966) |
| 0.3 | 0.9 | GO:0046041 | ITP metabolic process(GO:0046041) |
| 0.2 | 0.7 | GO:0006210 | pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) |
| 0.2 | 0.7 | GO:0080154 | regulation of fertilization(GO:0080154) |
| 0.2 | 0.7 | GO:1903450 | regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452) |
| 0.2 | 0.6 | GO:0034059 | response to anoxia(GO:0034059) |
| 0.2 | 1.2 | GO:0072675 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 0.2 | 0.5 | GO:1903410 | lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410) |
| 0.2 | 0.3 | GO:0060940 | epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) |
| 0.1 | 0.4 | GO:1904761 | negative regulation of myofibroblast differentiation(GO:1904761) |
| 0.1 | 1.0 | GO:0006642 | triglyceride mobilization(GO:0006642) |
| 0.1 | 0.4 | GO:1990709 | presynaptic active zone organization(GO:1990709) |
| 0.1 | 0.4 | GO:0070563 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420) |
| 0.1 | 1.0 | GO:0098912 | membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.1 | 0.4 | GO:0042137 | sequestering of neurotransmitter(GO:0042137) |
| 0.1 | 0.6 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
| 0.1 | 0.1 | GO:0061582 | intestinal epithelial cell migration(GO:0061582) |
| 0.1 | 1.3 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.1 | 0.8 | GO:0009256 | 10-formyltetrahydrofolate metabolic process(GO:0009256) |
| 0.1 | 0.3 | GO:0021526 | medial motor column neuron differentiation(GO:0021526) |
| 0.1 | 1.8 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.1 | 0.2 | GO:0060056 | mammary gland involution(GO:0060056) |
| 0.1 | 0.6 | GO:0035026 | leading edge cell differentiation(GO:0035026) |
| 0.1 | 0.3 | GO:0009405 | pathogenesis(GO:0009405) |
| 0.1 | 0.3 | GO:0044830 | modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254) |
| 0.1 | 0.6 | GO:0070086 | ubiquitin-dependent endocytosis(GO:0070086) |
| 0.1 | 0.5 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 0.1 | 0.3 | GO:0019858 | cytosine metabolic process(GO:0019858) |
| 0.1 | 0.5 | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
| 0.1 | 0.2 | GO:0036324 | vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) |
| 0.1 | 0.3 | GO:0044313 | protein K6-linked deubiquitination(GO:0044313) |
| 0.1 | 0.5 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
| 0.1 | 0.5 | GO:0090031 | positive regulation of steroid hormone biosynthetic process(GO:0090031) |
| 0.1 | 0.4 | GO:0008050 | female courtship behavior(GO:0008050) |
| 0.1 | 0.1 | GO:0043132 | NAD transport(GO:0043132) |
| 0.1 | 0.3 | GO:0001579 | medium-chain fatty acid transport(GO:0001579) |
| 0.1 | 0.6 | GO:0032380 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 0.1 | 0.2 | GO:1904339 | negative regulation of dopaminergic neuron differentiation(GO:1904339) |
| 0.1 | 0.2 | GO:0060364 | frontal suture morphogenesis(GO:0060364) |
| 0.1 | 0.6 | GO:0034436 | glycoprotein transport(GO:0034436) |
| 0.1 | 0.2 | GO:1901656 | glycoside transport(GO:1901656) |
| 0.1 | 0.3 | GO:0006844 | acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616) |
| 0.1 | 1.2 | GO:0000050 | urea cycle(GO:0000050) |
| 0.1 | 0.4 | GO:1905075 | occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075) |
| 0.1 | 0.6 | GO:0032439 | endosome localization(GO:0032439) |
| 0.1 | 0.2 | GO:0071262 | regulation of eIF2 alpha phosphorylation by amino acid starvation(GO:0060733) regulation of translational initiation in response to starvation(GO:0071262) positive regulation of translational initiation in response to starvation(GO:0071264) |
| 0.1 | 0.2 | GO:0002071 | glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560) |
| 0.1 | 0.2 | GO:0097359 | UDP-glucosylation(GO:0097359) |
| 0.1 | 0.7 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
| 0.1 | 0.2 | GO:2000588 | positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588) |
| 0.1 | 1.4 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 0.1 | 0.3 | GO:0090076 | relaxation of skeletal muscle(GO:0090076) |
| 0.1 | 0.2 | GO:0006533 | aspartate catabolic process(GO:0006533) |
| 0.1 | 0.3 | GO:1901503 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
| 0.1 | 0.2 | GO:0032290 | peripheral nervous system myelin formation(GO:0032290) |
| 0.1 | 0.4 | GO:0031179 | peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179) |
| 0.1 | 0.7 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
| 0.1 | 1.2 | GO:0021542 | dentate gyrus development(GO:0021542) |
| 0.1 | 0.4 | GO:0030538 | embryonic genitalia morphogenesis(GO:0030538) |
| 0.1 | 0.3 | GO:0015746 | tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746) |
| 0.1 | 0.2 | GO:0032792 | negative regulation of CREB transcription factor activity(GO:0032792) |
| 0.1 | 0.4 | GO:0010940 | positive regulation of necrotic cell death(GO:0010940) |
| 0.1 | 0.6 | GO:1902514 | regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514) |
| 0.1 | 0.1 | GO:0015917 | aminophospholipid transport(GO:0015917) |
| 0.1 | 0.3 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
| 0.1 | 0.4 | GO:0021943 | regulation of collagen catabolic process(GO:0010710) formation of radial glial scaffolds(GO:0021943) |
| 0.1 | 0.2 | GO:0097051 | establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) |
| 0.1 | 0.5 | GO:0070885 | negative regulation of calcineurin-NFAT signaling cascade(GO:0070885) |
| 0.1 | 0.4 | GO:0021592 | fourth ventricle development(GO:0021592) |
| 0.1 | 0.9 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
| 0.1 | 0.5 | GO:0032927 | positive regulation of activin receptor signaling pathway(GO:0032927) |
| 0.1 | 0.5 | GO:0035965 | cardiolipin acyl-chain remodeling(GO:0035965) |
| 0.1 | 0.2 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.1 | 0.3 | GO:1903903 | regulation of establishment of T cell polarity(GO:1903903) |
| 0.1 | 0.4 | GO:0070561 | vitamin D receptor signaling pathway(GO:0070561) |
| 0.1 | 0.4 | GO:0021527 | spinal cord association neuron differentiation(GO:0021527) |
| 0.1 | 0.2 | GO:0006848 | pyruvate transport(GO:0006848) mitochondrial pyruvate transport(GO:0006850) pyruvate transmembrane transport(GO:1901475) mitochondrial pyruvate transmembrane transport(GO:1902361) |
| 0.1 | 0.3 | GO:1901908 | diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
| 0.0 | 0.3 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
| 0.0 | 0.4 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
| 0.0 | 0.3 | GO:0060179 | male mating behavior(GO:0060179) |
| 0.0 | 0.6 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 0.0 | 0.5 | GO:0050428 | purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428) |
| 0.0 | 0.1 | GO:1903595 | positive regulation of histamine secretion by mast cell(GO:1903595) |
| 0.0 | 0.2 | GO:0071284 | cellular response to lead ion(GO:0071284) |
| 0.0 | 0.2 | GO:1903593 | regulation of histamine secretion by mast cell(GO:1903593) |
| 0.0 | 0.6 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.0 | 0.2 | GO:1903722 | negative regulation of exosomal secretion(GO:1903542) regulation of centriole elongation(GO:1903722) |
| 0.0 | 0.2 | GO:1903519 | penetration of zona pellucida(GO:0007341) positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747) |
| 0.0 | 0.4 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
| 0.0 | 0.4 | GO:0030242 | pexophagy(GO:0030242) |
| 0.0 | 0.4 | GO:0060355 | positive regulation of cell adhesion molecule production(GO:0060355) |
| 0.0 | 0.1 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
| 0.0 | 0.3 | GO:1903435 | positive regulation of constitutive secretory pathway(GO:1903435) |
| 0.0 | 0.5 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.0 | 0.7 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.0 | 0.9 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
| 0.0 | 0.2 | GO:1902109 | negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109) |
| 0.0 | 0.3 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 0.0 | 0.2 | GO:0016240 | autophagosome docking(GO:0016240) |
| 0.0 | 0.3 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
| 0.0 | 0.2 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 0.0 | 0.4 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) |
| 0.0 | 0.1 | GO:0045360 | regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720) cellular response to heparin(GO:0071504) positive regulation of metanephric glomerulus development(GO:0072300) |
| 0.0 | 0.1 | GO:0048633 | positive regulation of skeletal muscle tissue growth(GO:0048633) |
| 0.0 | 0.2 | GO:1902725 | negative regulation of satellite cell differentiation(GO:1902725) |
| 0.0 | 0.2 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
| 0.0 | 0.1 | GO:1904899 | regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922) |
| 0.0 | 0.5 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
| 0.0 | 0.2 | GO:0019072 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 0.0 | 0.2 | GO:0032902 | nerve growth factor production(GO:0032902) |
| 0.0 | 1.4 | GO:0021522 | spinal cord motor neuron differentiation(GO:0021522) |
| 0.0 | 0.1 | GO:0032506 | cytokinetic process(GO:0032506) |
| 0.0 | 0.3 | GO:0090394 | negative regulation of excitatory postsynaptic potential(GO:0090394) presynaptic membrane assembly(GO:0097105) |
| 0.0 | 0.4 | GO:0001561 | fatty acid alpha-oxidation(GO:0001561) |
| 0.0 | 0.1 | GO:0060214 | endocardium formation(GO:0060214) |
| 0.0 | 0.1 | GO:0010989 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) |
| 0.0 | 0.4 | GO:0070294 | renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294) |
| 0.0 | 0.2 | GO:1903575 | cornified envelope assembly(GO:1903575) |
| 0.0 | 0.1 | GO:2000252 | negative regulation of feeding behavior(GO:2000252) |
| 0.0 | 0.4 | GO:0051597 | response to methylmercury(GO:0051597) |
| 0.0 | 0.2 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 0.0 | 0.4 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) |
| 0.0 | 0.3 | GO:0018103 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
| 0.0 | 0.8 | GO:0035646 | endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757) |
| 0.0 | 0.2 | GO:0071934 | thiamine transmembrane transport(GO:0071934) |
| 0.0 | 0.4 | GO:1900086 | regulation of peptidyl-tyrosine autophosphorylation(GO:1900084) positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086) |
| 0.0 | 0.5 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.0 | 0.6 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) regulation of peptidyl-cysteine S-nitrosylation(GO:2000169) |
| 0.0 | 0.4 | GO:0045475 | locomotor rhythm(GO:0045475) |
| 0.0 | 0.2 | GO:0090649 | response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
| 0.0 | 0.2 | GO:1904693 | midbrain morphogenesis(GO:1904693) |
| 0.0 | 0.1 | GO:0090244 | Wnt signaling pathway involved in somitogenesis(GO:0090244) |
| 0.0 | 0.1 | GO:0035262 | gonad morphogenesis(GO:0035262) |
| 0.0 | 0.4 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.0 | 0.6 | GO:0007625 | grooming behavior(GO:0007625) |
| 0.0 | 0.2 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
| 0.0 | 1.0 | GO:1902284 | axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284) |
| 0.0 | 0.1 | GO:1903347 | negative regulation of bicellular tight junction assembly(GO:1903347) |
| 0.0 | 0.6 | GO:0045717 | negative regulation of fatty acid biosynthetic process(GO:0045717) |
| 0.0 | 0.6 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.0 | 0.5 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 0.0 | 0.3 | GO:0097039 | protein linear polyubiquitination(GO:0097039) |
| 0.0 | 0.1 | GO:0006127 | glycerophosphate shuttle(GO:0006127) |
| 0.0 | 0.1 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
| 0.0 | 0.2 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.0 | 0.5 | GO:0045792 | negative regulation of cell size(GO:0045792) |
| 0.0 | 0.2 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
| 0.0 | 1.0 | GO:1900449 | regulation of glutamate receptor signaling pathway(GO:1900449) |
| 0.0 | 0.1 | GO:0010701 | positive regulation of norepinephrine secretion(GO:0010701) |
| 0.0 | 0.1 | GO:0051466 | positive regulation of corticotropin-releasing hormone secretion(GO:0051466) |
| 0.0 | 0.8 | GO:0060314 | regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314) |
| 0.0 | 0.2 | GO:0042699 | follicle-stimulating hormone signaling pathway(GO:0042699) |
| 0.0 | 0.4 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.0 | 0.3 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.0 | 0.2 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731) |
| 0.0 | 0.6 | GO:0060074 | synapse maturation(GO:0060074) |
| 0.0 | 0.1 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.0 | 0.1 | GO:1902525 | regulation of protein monoubiquitination(GO:1902525) |
| 0.0 | 0.2 | GO:0045198 | establishment of epithelial cell apical/basal polarity(GO:0045198) |
| 0.0 | 0.0 | GO:1903069 | regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069) negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 0.0 | 0.3 | GO:0042373 | vitamin K metabolic process(GO:0042373) |
| 0.0 | 0.4 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.0 | 0.0 | GO:0006059 | hexitol metabolic process(GO:0006059) |
| 0.0 | 0.1 | GO:0032286 | central nervous system myelin maintenance(GO:0032286) |
| 0.0 | 0.2 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
| 0.0 | 0.0 | GO:0035360 | positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360) |
| 0.0 | 0.7 | GO:0090005 | negative regulation of establishment of protein localization to plasma membrane(GO:0090005) |
| 0.0 | 0.9 | GO:0050974 | detection of mechanical stimulus involved in sensory perception(GO:0050974) |
| 0.0 | 0.1 | GO:0090116 | C-5 methylation of cytosine(GO:0090116) |
| 0.0 | 0.7 | GO:0036150 | phosphatidylserine acyl-chain remodeling(GO:0036150) |
| 0.0 | 0.3 | GO:0046852 | positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852) |
| 0.0 | 1.1 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.0 | 0.0 | GO:0010847 | regulation of chromatin assembly(GO:0010847) |
| 0.0 | 0.1 | GO:1904562 | phosphatidylinositol 5-phosphate metabolic process(GO:1904562) |
| 0.0 | 0.1 | GO:1903691 | positive regulation of wound healing, spreading of epidermal cells(GO:1903691) |
| 0.0 | 0.1 | GO:0001880 | Mullerian duct regression(GO:0001880) |
| 0.0 | 0.2 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
| 0.0 | 0.4 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 0.0 | 0.2 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
| 0.0 | 0.2 | GO:0060134 | prepulse inhibition(GO:0060134) |
| 0.0 | 0.4 | GO:0036152 | phosphatidylethanolamine acyl-chain remodeling(GO:0036152) |
| 0.0 | 0.6 | GO:0030539 | male genitalia development(GO:0030539) |
| 0.0 | 0.4 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.0 | 0.4 | GO:0051197 | positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) |
| 0.0 | 0.1 | GO:0060023 | soft palate development(GO:0060023) |
| 0.0 | 0.1 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
| 0.0 | 0.9 | GO:0019228 | neuronal action potential(GO:0019228) |
| 0.0 | 0.1 | GO:0048294 | negative regulation of isotype switching to IgE isotypes(GO:0048294) |
| 0.0 | 0.1 | GO:1901143 | insulin catabolic process(GO:1901143) |
| 0.0 | 0.0 | GO:0060730 | regulation of intestinal epithelial structure maintenance(GO:0060730) |
| 0.0 | 0.6 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.0 | 0.1 | GO:0072356 | chromosome passenger complex localization to kinetochore(GO:0072356) |
| 0.0 | 0.0 | GO:0097360 | chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382) |
| 0.0 | 0.1 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
| 0.0 | 0.2 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
| 0.0 | 0.1 | GO:0046947 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
| 0.0 | 0.5 | GO:2000615 | regulation of histone H3-K9 acetylation(GO:2000615) |
| 0.0 | 0.2 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.0 | 0.4 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.0 | 0.2 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.0 | 0.1 | GO:0044860 | protein localization to plasma membrane raft(GO:0044860) |
| 0.0 | 0.2 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 0.0 | 0.3 | GO:0060628 | regulation of ER to Golgi vesicle-mediated transport(GO:0060628) |
| 0.0 | 0.0 | GO:0035973 | aggrephagy(GO:0035973) |
| 0.0 | 0.1 | GO:0001826 | inner cell mass cell differentiation(GO:0001826) |
| 0.0 | 0.1 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
| 0.0 | 0.0 | GO:0021919 | BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919) |
| 0.0 | 0.0 | GO:0031548 | regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548) |
| 0.0 | 0.1 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 0.0 | 0.1 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.0 | 0.2 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
| 0.0 | 0.1 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
| 0.0 | 0.0 | GO:0009443 | pyridoxal 5'-phosphate salvage(GO:0009443) |
| 0.0 | 0.1 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.0 | 0.2 | GO:0033147 | negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147) |
| 0.0 | 0.1 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
| 0.0 | 0.1 | GO:0032310 | prostaglandin secretion(GO:0032310) |
| 0.0 | 0.4 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.0 | 0.6 | GO:0006693 | prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693) |
| 0.0 | 0.0 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
| 0.0 | 0.2 | GO:0072321 | chaperone-mediated protein transport(GO:0072321) |
| 0.0 | 0.2 | GO:0015074 | DNA integration(GO:0015074) |
| 0.0 | 0.1 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
| 0.0 | 0.1 | GO:0019856 | 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856) |
| 0.0 | 0.1 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.0 | 1.8 | GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332) |
| 0.0 | 0.2 | GO:0018342 | protein prenylation(GO:0018342) prenylation(GO:0097354) |
| 0.0 | 1.3 | GO:0006687 | glycosphingolipid metabolic process(GO:0006687) |
| 0.0 | 0.4 | GO:0044872 | lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872) |
| 0.0 | 0.1 | GO:0006104 | succinyl-CoA metabolic process(GO:0006104) |
| 0.0 | 0.0 | GO:0000350 | generation of catalytic spliceosome for second transesterification step(GO:0000350) |
| 0.0 | 0.1 | GO:0061084 | regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) |
| 0.0 | 0.0 | GO:0034499 | late endosome to Golgi transport(GO:0034499) |
| 0.0 | 0.1 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
| 0.0 | 0.0 | GO:1903778 | protein localization to vacuolar membrane(GO:1903778) |
| 0.0 | 0.1 | GO:0070315 | G1 to G0 transition involved in cell differentiation(GO:0070315) |
| 0.0 | 0.0 | GO:0006601 | creatine biosynthetic process(GO:0006601) |
| 0.0 | 0.2 | GO:0043966 | histone H3 acetylation(GO:0043966) |
| 0.0 | 0.8 | GO:0035329 | hippo signaling(GO:0035329) |
| 0.0 | 0.2 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.0 | 0.1 | GO:1900239 | phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239) |
| 0.0 | 0.0 | GO:0032223 | negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212) |
| 0.0 | 0.2 | GO:1903432 | regulation of TORC1 signaling(GO:1903432) |
| 0.0 | 0.2 | GO:0008045 | motor neuron axon guidance(GO:0008045) |
| 0.0 | 0.1 | GO:2000773 | negative regulation of cellular senescence(GO:2000773) |
| 0.0 | 0.0 | GO:1902544 | regulation of DNA N-glycosylase activity(GO:1902544) |
| 0.0 | 0.1 | GO:0015798 | myo-inositol transport(GO:0015798) |
| 0.0 | 1.5 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) |
| 0.0 | 0.3 | GO:0051639 | actin filament network formation(GO:0051639) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.9 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 0.1 | 0.4 | GO:0034677 | integrin alpha7-beta1 complex(GO:0034677) |
| 0.1 | 0.8 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
| 0.1 | 0.5 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.1 | 0.5 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.1 | 1.8 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.1 | 0.3 | GO:1902737 | dendritic filopodium(GO:1902737) |
| 0.1 | 1.0 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.1 | 0.3 | GO:0005595 | collagen type XII trimer(GO:0005595) |
| 0.1 | 0.8 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 0.1 | 0.7 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.1 | 0.1 | GO:0044308 | axonal spine(GO:0044308) |
| 0.1 | 0.2 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 0.1 | 0.6 | GO:0016013 | syntrophin complex(GO:0016013) |
| 0.1 | 0.3 | GO:0071458 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) |
| 0.1 | 0.5 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 0.1 | 0.6 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.1 | 0.9 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.1 | 0.2 | GO:0002947 | tumor necrosis factor receptor superfamily complex(GO:0002947) |
| 0.1 | 0.2 | GO:0070931 | Golgi-associated vesicle lumen(GO:0070931) |
| 0.1 | 0.2 | GO:0097422 | tubular endosome(GO:0097422) |
| 0.0 | 0.4 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.0 | 0.8 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.0 | 1.1 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.0 | 0.3 | GO:0071797 | LUBAC complex(GO:0071797) |
| 0.0 | 0.5 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.0 | 0.5 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.0 | 0.3 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.0 | 0.6 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 0.0 | 0.4 | GO:0070081 | clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083) |
| 0.0 | 1.1 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.0 | 0.3 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 0.0 | 0.2 | GO:0031905 | early endosome lumen(GO:0031905) |
| 0.0 | 0.3 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.0 | 0.1 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.0 | 0.4 | GO:0045179 | apical cortex(GO:0045179) |
| 0.0 | 1.2 | GO:0030057 | desmosome(GO:0030057) |
| 0.0 | 0.2 | GO:0070695 | FHF complex(GO:0070695) |
| 0.0 | 0.3 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
| 0.0 | 0.5 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 0.7 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
| 0.0 | 0.2 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.0 | 0.3 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.0 | 0.2 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.0 | 0.4 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.0 | 0.3 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.0 | 0.1 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 0.0 | 1.4 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 0.6 | GO:0032585 | multivesicular body membrane(GO:0032585) |
| 0.0 | 0.5 | GO:0044232 | organelle membrane contact site(GO:0044232) |
| 0.0 | 0.6 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.0 | 0.1 | GO:0045160 | myosin I complex(GO:0045160) |
| 0.0 | 0.1 | GO:0016939 | kinesin II complex(GO:0016939) |
| 0.0 | 0.1 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.0 | 0.3 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 0.1 | GO:0033655 | host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655) |
| 0.0 | 1.4 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 1.2 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 0.2 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.0 | 0.5 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.0 | 0.1 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
| 0.0 | 0.1 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.0 | 1.8 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.0 | 0.3 | GO:0090543 | Flemming body(GO:0090543) |
| 0.0 | 1.1 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.1 | GO:0030062 | mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062) |
| 0.0 | 0.0 | GO:0097635 | extrinsic component of autophagosome membrane(GO:0097635) |
| 0.0 | 0.4 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
| 0.0 | 0.8 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.0 | 0.1 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 0.0 | 0.3 | GO:0001741 | XY body(GO:0001741) |
| 0.0 | 0.0 | GO:0000939 | condensed chromosome inner kinetochore(GO:0000939) |
| 0.0 | 0.2 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 0.1 | GO:0072487 | MSL complex(GO:0072487) |
| 0.0 | 0.4 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.0 | 0.6 | GO:0030660 | Golgi-associated vesicle membrane(GO:0030660) |
| 0.0 | 0.0 | GO:0071020 | post-spliceosomal complex(GO:0071020) |
| 0.0 | 0.5 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.4 | GO:0031304 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.0 | 1.3 | GO:0005776 | autophagosome(GO:0005776) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 0.3 | GO:0015227 | acyl carnitine transmembrane transporter activity(GO:0015227) |
| 0.2 | 0.7 | GO:0032427 | GBD domain binding(GO:0032427) |
| 0.1 | 0.9 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.1 | 0.4 | GO:0019166 | trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
| 0.1 | 0.4 | GO:0004531 | deoxyribonuclease II activity(GO:0004531) |
| 0.1 | 0.6 | GO:0034189 | very-low-density lipoprotein particle binding(GO:0034189) |
| 0.1 | 1.2 | GO:0016215 | stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) |
| 0.1 | 1.2 | GO:0001025 | RNA polymerase III transcription factor binding(GO:0001025) |
| 0.1 | 0.8 | GO:0031849 | olfactory receptor binding(GO:0031849) |
| 0.1 | 1.0 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.1 | 0.7 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
| 0.1 | 0.4 | GO:0047322 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405) |
| 0.1 | 0.6 | GO:0003985 | acetyl-CoA C-acetyltransferase activity(GO:0003985) |
| 0.1 | 0.5 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 0.1 | 0.4 | GO:0015616 | DNA translocase activity(GO:0015616) |
| 0.1 | 0.5 | GO:0005289 | high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292) |
| 0.1 | 0.3 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
| 0.1 | 0.6 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.1 | 0.6 | GO:0036132 | 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522) |
| 0.1 | 0.2 | GO:0035651 | AP-3 adaptor complex binding(GO:0035651) |
| 0.1 | 0.2 | GO:0003980 | UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) |
| 0.1 | 0.4 | GO:0044378 | non-sequence-specific DNA binding, bending(GO:0044378) |
| 0.1 | 0.2 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
| 0.1 | 0.5 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
| 0.1 | 0.2 | GO:0004366 | glycerol-3-phosphate O-acyltransferase activity(GO:0004366) |
| 0.1 | 0.4 | GO:0004504 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
| 0.1 | 0.3 | GO:0015142 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
| 0.1 | 0.3 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.1 | 0.5 | GO:0017002 | activin-activated receptor activity(GO:0017002) |
| 0.1 | 0.5 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.1 | 0.4 | GO:0004985 | opioid receptor activity(GO:0004985) |
| 0.1 | 0.2 | GO:0031896 | vasopressin receptor binding(GO:0031893) V2 vasopressin receptor binding(GO:0031896) |
| 0.1 | 0.4 | GO:0004466 | long-chain-acyl-CoA dehydrogenase activity(GO:0004466) |
| 0.1 | 0.2 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
| 0.1 | 0.3 | GO:0047057 | oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057) |
| 0.1 | 0.6 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.1 | 0.9 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 0.1 | 0.3 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 0.1 | 0.2 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 0.1 | 0.9 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.1 | 0.3 | GO:0000298 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848) |
| 0.1 | 0.4 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
| 0.1 | 0.2 | GO:0046969 | histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) |
| 0.1 | 0.4 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.1 | 0.2 | GO:0036487 | nitric-oxide synthase inhibitor activity(GO:0036487) |
| 0.1 | 0.2 | GO:0004781 | adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781) |
| 0.0 | 0.6 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.0 | 0.3 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
| 0.0 | 0.2 | GO:0032767 | superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767) |
| 0.0 | 0.2 | GO:0004165 | dodecenoyl-CoA delta-isomerase activity(GO:0004165) |
| 0.0 | 0.2 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 0.0 | 0.2 | GO:0004118 | cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) |
| 0.0 | 0.9 | GO:0005522 | profilin binding(GO:0005522) |
| 0.0 | 0.2 | GO:0052740 | 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
| 0.0 | 0.3 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.0 | 0.3 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.0 | 0.2 | GO:0003988 | acetyl-CoA C-acyltransferase activity(GO:0003988) |
| 0.0 | 0.8 | GO:0016742 | hydroxymethyl-, formyl- and related transferase activity(GO:0016742) |
| 0.0 | 0.1 | GO:0090541 | MIT domain binding(GO:0090541) |
| 0.0 | 0.4 | GO:1904929 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 0.0 | 0.4 | GO:0008504 | monoamine transmembrane transporter activity(GO:0008504) |
| 0.0 | 0.2 | GO:0008798 | beta-aspartyl-peptidase activity(GO:0008798) |
| 0.0 | 0.2 | GO:0097001 | glycosphingolipid binding(GO:0043208) ceramide binding(GO:0097001) |
| 0.0 | 0.2 | GO:0000293 | ferric-chelate reductase activity(GO:0000293) |
| 0.0 | 0.2 | GO:0015403 | thiamine uptake transmembrane transporter activity(GO:0015403) |
| 0.0 | 0.9 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.0 | 0.6 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 0.0 | 1.2 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 0.4 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
| 0.0 | 0.5 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.0 | 0.2 | GO:0072345 | NAADP-sensitive calcium-release channel activity(GO:0072345) |
| 0.0 | 0.7 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.0 | 0.3 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.0 | 0.1 | GO:0031752 | D5 dopamine receptor binding(GO:0031752) |
| 0.0 | 0.2 | GO:0031750 | D3 dopamine receptor binding(GO:0031750) |
| 0.0 | 0.1 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
| 0.0 | 0.1 | GO:0052591 | sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591) |
| 0.0 | 0.1 | GO:0050211 | procollagen galactosyltransferase activity(GO:0050211) |
| 0.0 | 0.1 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
| 0.0 | 0.8 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.0 | 0.1 | GO:0034188 | apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556) |
| 0.0 | 0.4 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.0 | 0.2 | GO:0050780 | dopamine receptor binding(GO:0050780) |
| 0.0 | 0.3 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 0.0 | 1.0 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.0 | 0.1 | GO:0097003 | adipokinetic hormone receptor activity(GO:0097003) |
| 0.0 | 0.1 | GO:0016404 | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404) |
| 0.0 | 0.8 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.0 | 0.6 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
| 0.0 | 0.2 | GO:0010385 | double-stranded methylated DNA binding(GO:0010385) |
| 0.0 | 0.2 | GO:0016413 | O-acetyltransferase activity(GO:0016413) |
| 0.0 | 3.2 | GO:0002039 | p53 binding(GO:0002039) |
| 0.0 | 0.4 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.0 | 0.1 | GO:0033878 | hormone-sensitive lipase activity(GO:0033878) |
| 0.0 | 0.5 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.0 | 1.3 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.0 | 0.8 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.3 | GO:0004467 | long-chain fatty acid-CoA ligase activity(GO:0004467) |
| 0.0 | 0.5 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.0 | 0.1 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
| 0.0 | 0.7 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.0 | 0.1 | GO:0019208 | phosphatase regulator activity(GO:0019208) |
| 0.0 | 0.4 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
| 0.0 | 0.3 | GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) |
| 0.0 | 0.6 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.0 | 0.3 | GO:0086008 | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008) |
| 0.0 | 0.4 | GO:0016594 | glycine binding(GO:0016594) |
| 0.0 | 0.2 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 0.0 | 0.1 | GO:0004774 | succinate-CoA ligase activity(GO:0004774) |
| 0.0 | 0.1 | GO:1904928 | coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928) |
| 0.0 | 0.7 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.0 | 0.4 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.0 | 0.3 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
| 0.0 | 0.1 | GO:0031626 | beta-endorphin binding(GO:0031626) |
| 0.0 | 0.1 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.0 | 0.2 | GO:0008318 | protein prenyltransferase activity(GO:0008318) |
| 0.0 | 0.3 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.0 | 0.3 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.0 | 0.1 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 0.0 | 0.3 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 0.1 | GO:0032451 | demethylase activity(GO:0032451) histone demethylase activity(GO:0032452) |
| 0.0 | 0.4 | GO:0031404 | chloride ion binding(GO:0031404) |
| 0.0 | 0.0 | GO:0008193 | tRNA guanylyltransferase activity(GO:0008193) |
| 0.0 | 0.3 | GO:0033549 | MAP kinase phosphatase activity(GO:0033549) |
| 0.0 | 0.2 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.0 | 0.0 | GO:0000384 | first spliceosomal transesterification activity(GO:0000384) |
| 0.0 | 0.0 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 0.2 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.0 | 0.5 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.0 | 0.1 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
| 0.0 | 0.4 | GO:0015299 | solute:proton antiporter activity(GO:0015299) |
| 0.0 | 0.0 | GO:0008478 | pyridoxal kinase activity(GO:0008478) |
| 0.0 | 0.1 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 0.0 | 0.4 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.0 | 0.1 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.0 | 0.1 | GO:0009041 | uridylate kinase activity(GO:0009041) |
| 0.0 | 0.6 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 0.7 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 0.0 | GO:0015226 | amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226) quaternary ammonium group transmembrane transporter activity(GO:0015651) |
| 0.0 | 0.4 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
| 0.0 | 0.2 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
| 0.0 | 0.2 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
| 0.0 | 0.2 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.0 | 1.8 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.2 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.0 | 0.2 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.0 | 0.3 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.7 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 0.8 | PID_RANBP2_PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.0 | 1.0 | PID_IL5_PATHWAY | IL5-mediated signaling events |
| 0.0 | 1.5 | PID_REELIN_PATHWAY | Reelin signaling pathway |
| 0.0 | 0.6 | PID_THROMBIN_PAR4_PATHWAY | PAR4-mediated thrombin signaling events |
| 0.0 | 1.4 | PID_ALK1_PATHWAY | ALK1 signaling events |
| 0.0 | 0.9 | PID_IL8_CXCR1_PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.0 | 0.1 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.0 | 1.8 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.8 | PID_MTOR_4PATHWAY | mTOR signaling pathway |
| 0.0 | 1.1 | PID_RAS_PATHWAY | Regulation of Ras family activation |
| 0.0 | 2.0 | PID_LKB1_PATHWAY | LKB1 signaling events |
| 0.0 | 0.7 | PID_CERAMIDE_PATHWAY | Ceramide signaling pathway |
| 0.0 | 0.4 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 0.4 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.4 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 0.5 | PID_MYC_PATHWAY | C-MYC pathway |
| 0.0 | 0.5 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
| 0.0 | 0.6 | SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.0 | 0.4 | PID_FCER1_PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.0 | 0.7 | PID_BMP_PATHWAY | BMP receptor signaling |
| 0.0 | 0.6 | PID_PS1_PATHWAY | Presenilin action in Notch and Wnt signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.1 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.1 | 1.2 | REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.1 | 1.3 | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.1 | 0.1 | REACTOME_SIGNALLING_TO_RAS | Genes involved in Signalling to RAS |
| 0.0 | 0.1 | REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.0 | 1.0 | REACTOME_SYNTHESIS_OF_PE | Genes involved in Synthesis of PE |
| 0.0 | 0.1 | REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR | Genes involved in Thromboxane signalling through TP receptor |
| 0.0 | 0.7 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.0 | 1.5 | REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
| 0.0 | 0.6 | REACTOME_ERKS_ARE_INACTIVATED | Genes involved in ERKs are inactivated |
| 0.0 | 1.2 | REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.0 | 0.6 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
| 0.0 | 1.2 | REACTOME_LYSOSOME_VESICLE_BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.0 | 0.8 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.0 | 0.7 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 0.4 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PS | Genes involved in Acyl chain remodelling of PS |
| 0.0 | 0.6 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.0 | 0.3 | REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING | Genes involved in Spry regulation of FGF signaling |
| 0.0 | 0.6 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.0 | 0.5 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 | Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1 |
| 0.0 | 1.1 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.5 | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.0 | 0.4 | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.0 | 1.2 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 0.3 | REACTOME_EGFR_DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 0.7 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 0.4 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.0 | 0.5 | REACTOME_SYNTHESIS_OF_PA | Genes involved in Synthesis of PA |
| 0.0 | 0.3 | REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS | Genes involved in NRIF signals cell death from the nucleus |
| 0.0 | 0.1 | REACTOME_ADP_SIGNALLING_THROUGH_P2RY1 | Genes involved in ADP signalling through P2Y purinoceptor 1 |
| 0.0 | 0.5 | REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
| 0.0 | 0.5 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 0.1 | REACTOME_G_ALPHA1213_SIGNALLING_EVENTS | Genes involved in G alpha (12/13) signalling events |
| 0.0 | 0.4 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
| 0.0 | 0.6 | REACTOME_GLYCOSPHINGOLIPID_METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.0 | 0.7 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.4 | REACTOME_METABOLISM_OF_PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.0 | 0.4 | REACTOME_REGULATION_OF_SIGNALING_BY_CBL | Genes involved in Regulation of signaling by CBL |
| 0.0 | 0.1 | REACTOME_ARMS_MEDIATED_ACTIVATION | Genes involved in ARMS-mediated activation |
| 0.0 | 0.3 | REACTOME_P38MAPK_EVENTS | Genes involved in p38MAPK events |
| 0.0 | 0.3 | REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.0 | 0.2 | REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
