Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w6a_vs_wt_vs_wt.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp_repos |
| Phenotype | w6a_vs_wt.cls#ago1w6a_versus_ago1gfp_repos |
| Upregulated in class | ago1w6a |
| GeneSet | KEGG_PROTEASOME |
| Enrichment Score (ES) | 0.4459099 |
| Normalized Enrichment Score (NES) | 1.4896948 |
| Nominal p-value | 0.027568921 |
| FDR q-value | 0.14051126 |
| FWER p-Value | 0.881 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PSMB9 | NA | PSMB9 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) | 325 | 1.706 | 0.0908 | Yes |
| 2 | PSMD6 | NA | PSMD6 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 1400 | 0.743 | 0.0627 | Yes |
| 3 | PSME3 | NA | PSME3 Entrez, Source | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) | 1401 | 0.743 | 0.1125 | Yes |
| 4 | PSMD12 | NA | PSMD12 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 1495 | 0.718 | 0.1539 | Yes |
| 5 | PSMC4 | NA | PSMC4 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 1696 | 0.659 | 0.1836 | Yes |
| 6 | PSMD2 | NA | PSMD2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 1784 | 0.637 | 0.2199 | Yes |
| 7 | PSMB10 | NA | PSMB10 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 10 | 2030 | 0.581 | 0.2411 | Yes |
| 8 | PSMD8 | NA | PSMD8 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 2095 | 0.570 | 0.2747 | Yes |
| 9 | PSMA5 | NA | PSMA5 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 5 | 2251 | 0.542 | 0.2998 | Yes |
| 10 | PSMD11 | NA | PSMD11 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 2638 | 0.477 | 0.3038 | Yes |
| 11 | PSMD1 | NA | PSMD1 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 2701 | 0.467 | 0.3306 | Yes |
| 12 | PSMD3 | NA | PSMD3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 3003 | 0.421 | 0.3370 | Yes |
| 13 | PSMA6 | NA | PSMA6 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 6 | 3102 | 0.408 | 0.3572 | Yes |
| 14 | PSMC1 | NA | PSMC1 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | 3344 | 0.376 | 0.3650 | Yes |
| 15 | PSMB7 | NA | PSMB7 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 7 | 3357 | 0.375 | 0.3892 | Yes |
| 16 | PSME2 | NA | PSME2 Entrez, Source | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 3736 | 0.329 | 0.3839 | Yes |
| 17 | PSMB2 | NA | PSMB2 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 2 | 3784 | 0.323 | 0.4021 | Yes |
| 18 | PSMD14 | NA | PSMD14 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 4018 | 0.295 | 0.4050 | Yes |
| 19 | PSMC3 | NA | PSMC3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 4033 | 0.294 | 0.4237 | Yes |
| 20 | PSMC5 | NA | PSMC5 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | 4188 | 0.279 | 0.4312 | Yes |
| 21 | PSMD13 | NA | PSMD13 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 4460 | 0.248 | 0.4282 | Yes |
| 22 | PSMC2 | NA | PSMC2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | 4631 | 0.229 | 0.4312 | Yes |
| 23 | PSMC6 | NA | PSMC6 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 4641 | 0.229 | 0.4459 | Yes |
| 24 | PSME1 | NA | PSME1 Entrez, Source | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 4947 | 0.197 | 0.4370 | No |
| 25 | PSMF1 | NA | PSMF1 Entrez, Source | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 5251 | 0.166 | 0.4262 | No |
| 26 | PSMA3 | NA | PSMA3 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 3 | 5405 | 0.150 | 0.4251 | No |
| 27 | POMP | NA | POMP Entrez, Source | proteasome maturation protein | 5629 | 0.124 | 0.4173 | No |
| 28 | PSMA4 | NA | PSMA4 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 4 | 6158 | 0.072 | 0.3838 | No |
| 29 | PSME4 | NA | PSME4 Entrez, Source | proteasome (prosome, macropain) activator subunit 4 | 6400 | 0.049 | 0.3696 | No |
| 30 | PSMA7 | NA | PSMA7 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 7 | 6718 | 0.015 | 0.3477 | No |
| 31 | PSMA2 | NA | PSMA2 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 2 | 7269 | -0.041 | 0.3105 | No |
| 32 | PSMD7 | NA | PSMD7 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog) | 7374 | -0.054 | 0.3066 | No |
| 33 | PSMB4 | NA | PSMB4 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 4 | 7534 | -0.069 | 0.2997 | No |
| 34 | PSMD4 | NA | PSMD4 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 7967 | -0.110 | 0.2758 | No |
| 35 | PSMB6 | NA | PSMB6 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 6 | 8515 | -0.170 | 0.2475 | No |
| 36 | PSMB5 | NA | PSMB5 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 5 | 8605 | -0.180 | 0.2531 | No |
| 37 | PSMB3 | NA | PSMB3 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 3 | 9617 | -0.310 | 0.2006 | No |
| 38 | PSMB1 | NA | PSMB1 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 1 | 10168 | -0.389 | 0.1868 | No |
| 39 | PSMB8 | NA | PSMB8 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 10667 | -0.471 | 0.1822 | No |
| 40 | PSMA1 | NA | PSMA1 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 1 | 11829 | -0.705 | 0.1453 | No |
