Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w6a_vs_wt_vs_wt.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp_repos |
| Phenotype | w6a_vs_wt.cls#ago1w6a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | KEGG_PROPANOATE_METABOLISM |
| Enrichment Score (ES) | -0.671494 |
| Normalized Enrichment Score (NES) | -1.9857386 |
| Nominal p-value | 0.001754386 |
| FDR q-value | 7.902285E-4 |
| FWER p-Value | 0.004 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ACSS3 | NA | 4304 | 0.265 | -0.2985 | No | ||
| 2 | ALDH1B1 | NA | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 5084 | 0.183 | -0.3458 | No |
| 3 | LDHA | NA | LDHA Entrez, Source | lactate dehydrogenase A | 6424 | 0.047 | -0.4404 | No |
| 4 | LDHAL6A | NA | LDHAL6A Entrez, Source | lactate dehydrogenase A-like 6A | 6986 | -0.013 | -0.4804 | No |
| 5 | ACACB | NA | ACACB Entrez, Source | acetyl-Coenzyme A carboxylase beta | 7907 | -0.105 | -0.5418 | No |
| 6 | MLYCD | NA | MLYCD Entrez, Source | malonyl-CoA decarboxylase | 8788 | -0.201 | -0.5955 | No |
| 7 | SUCLA2 | NA | SUCLA2 Entrez, Source | succinate-CoA ligase, ADP-forming, beta subunit | 9278 | -0.260 | -0.6179 | No |
| 8 | ALDH3A2 | NA | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 9636 | -0.312 | -0.6282 | No |
| 9 | HIBCH | NA | HIBCH Entrez, Source | 3-hydroxyisobutyryl-Coenzyme A hydrolase | 9987 | -0.362 | -0.6354 | No |
| 10 | LDHB | NA | LDHB Entrez, Source | lactate dehydrogenase B | 10486 | -0.440 | -0.6495 | Yes |
| 11 | EHHADH | NA | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 10749 | -0.483 | -0.6443 | Yes |
| 12 | SUCLG2 | NA | SUCLG2 Entrez, Source | succinate-CoA ligase, GDP-forming, beta subunit | 10808 | -0.494 | -0.6237 | Yes |
| 13 | ALDH9A1 | NA | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 10955 | -0.519 | -0.6083 | Yes |
| 14 | PCCB | NA | PCCB Entrez, Source | propionyl Coenzyme A carboxylase, beta polypeptide | 10973 | -0.522 | -0.5834 | Yes |
| 15 | ACSS2 | NA | ACSS2 Entrez, Source | acyl-CoA synthetase short-chain family member 2 | 11071 | -0.540 | -0.5634 | Yes |
| 16 | LDHAL6B | NA | LDHAL6B Entrez, Source | lactate dehydrogenase A-like 6B | 11102 | -0.547 | -0.5382 | Yes |
| 17 | ECHS1 | NA | ECHS1 Entrez, Source | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 11963 | -0.742 | -0.5634 | Yes |
| 18 | ALDH7A1 | NA | ALDH7A1 Entrez, Source | aldehyde dehydrogenase 7 family, member A1 | 12010 | -0.760 | -0.5287 | Yes |
| 19 | SUCLG1 | NA | SUCLG1 Entrez, Source | succinate-CoA ligase, GDP-forming, alpha subunit | 12083 | -0.781 | -0.4948 | Yes |
| 20 | ACADM | NA | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 12101 | -0.786 | -0.4567 | Yes |
| 21 | HADHA | NA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 12220 | -0.825 | -0.4239 | Yes |
| 22 | ACACA | NA | ACACA Entrez, Source | acetyl-Coenzyme A carboxylase alpha | 12340 | -0.869 | -0.3890 | Yes |
| 23 | ABAT | NA | ABAT Entrez, Source | 4-aminobutyrate aminotransferase | 12624 | -0.996 | -0.3597 | Yes |
| 24 | MCEE | NA | MCEE Entrez, Source | methylmalonyl CoA epimerase | 12681 | -1.026 | -0.3124 | Yes |
| 25 | ACAT2 | NA | ACAT2 Entrez, Source | acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase) | 12819 | -1.099 | -0.2673 | Yes |
| 26 | MUT | NA | MUT Entrez, Source | methylmalonyl Coenzyme A mutase | 12830 | -1.107 | -0.2126 | Yes |
| 27 | ALDH2 | NA | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 13109 | -1.302 | -0.1676 | Yes |
| 28 | ACAT1 | NA | ACAT1 Entrez, Source | acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) | 13202 | -1.396 | -0.1043 | Yes |
| 29 | ALDH6A1 | NA | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 13276 | -1.487 | -0.0352 | Yes |
| 30 | PCCA | NA | PCCA Entrez, Source | propionyl Coenzyme A carboxylase, alpha polypeptide | 13298 | -1.509 | 0.0388 | Yes |
