Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w6a_vs_wt_vs_wt.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp_repos |
| Phenotype | w6a_vs_wt.cls#ago1w6a_versus_ago1gfp_repos |
| Upregulated in class | ago1w6a |
| GeneSet | KEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION |
| Enrichment Score (ES) | 0.4768328 |
| Normalized Enrichment Score (NES) | 1.626071 |
| Nominal p-value | 0.009661836 |
| FDR q-value | 0.08214746 |
| FWER p-Value | 0.515 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CLDN1 | NA | CLDN1 Entrez, Source | claudin 1 | 306 | 1.751 | 0.0357 | Yes |
| 2 | TUBB3 | NA | TUBB3 Entrez, Source | tubulin, beta 3 | 367 | 1.566 | 0.0831 | Yes |
| 3 | TUBB2A | NA | TUBB2A Entrez, Source | tubulin, beta 2A | 389 | 1.523 | 0.1319 | Yes |
| 4 | TUBA1C | NA | 418 | 1.481 | 0.1788 | Yes | ||
| 5 | TUBB4B | NA | 490 | 1.327 | 0.2175 | Yes | ||
| 6 | ACTG1 | NA | ACTG1 Entrez, Source | actin, gamma 1 | 583 | 1.201 | 0.2505 | Yes |
| 7 | TUBB | NA | TUBB Entrez, Source | tubulin, beta | 585 | 1.199 | 0.2901 | Yes |
| 8 | TUBA4A | NA | 599 | 1.183 | 0.3283 | Yes | ||
| 9 | KRT18 | NA | KRT18 Entrez, Source | keratin 18 | 664 | 1.127 | 0.3609 | Yes |
| 10 | TLR4 | NA | TLR4 Entrez, Source | toll-like receptor 4 | 729 | 1.068 | 0.3915 | Yes |
| 11 | TUBA1B | NA | 746 | 1.056 | 0.4253 | Yes | ||
| 12 | NCL | NA | NCL Entrez, Source | nucleolin | 1107 | 0.848 | 0.4272 | Yes |
| 13 | ACTB | NA | ACTB Entrez, Source | actin, beta | 1127 | 0.840 | 0.4536 | Yes |
| 14 | TUBA8 | NA | TUBA8 Entrez, Source | tubulin, alpha 8 | 1347 | 0.758 | 0.4627 | Yes |
| 15 | TUBA1A | NA | 1595 | 0.690 | 0.4676 | Yes | ||
| 16 | ARPC5L | NA | ARPC5L Entrez, Source | actin related protein 2/3 complex, subunit 5-like | 1761 | 0.641 | 0.4768 | Yes |
| 17 | TUBA3D | NA | 2894 | 0.435 | 0.4091 | No | ||
| 18 | ARPC4 | NA | ARPC4 Entrez, Source | actin related protein 2/3 complex, subunit 4, 20kDa | 2987 | 0.423 | 0.4164 | No |
| 19 | YWHAQ | NA | YWHAQ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 3010 | 0.420 | 0.4287 | No |
| 20 | ARHGEF2 | NA | ARHGEF2 Entrez, Source | rho/rac guanine nucleotide exchange factor (GEF) 2 | 3089 | 0.409 | 0.4365 | No |
| 21 | EZR | NA | 3287 | 0.383 | 0.4349 | No | ||
| 22 | YWHAZ | NA | YWHAZ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 3862 | 0.315 | 0.4037 | No |
| 23 | WAS | NA | WAS Entrez, Source | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 3921 | 0.307 | 0.4096 | No |
| 24 | CTTN | NA | CTTN Entrez, Source | cortactin | 4209 | 0.277 | 0.3980 | No |
| 25 | ROCK1 | NA | ROCK1 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 1 | 4370 | 0.257 | 0.3949 | No |
| 26 | ARPC5 | NA | ARPC5 Entrez, Source | actin related protein 2/3 complex, subunit 5, 16kDa | 4664 | 0.227 | 0.3811 | No |
| 27 | ROCK2 | NA | ROCK2 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 2 | 4724 | 0.219 | 0.3841 | No |
| 28 | CDH1 | NA | CDH1 Entrez, Source | cadherin 1, type 1, E-cadherin (epithelial) | 5859 | 0.102 | 0.3052 | No |
| 29 | ARPC2 | NA | ARPC2 Entrez, Source | actin related protein 2/3 complex, subunit 2, 34kDa | 6055 | 0.081 | 0.2937 | No |
| 30 | ARPC1A | NA | ARPC1A Entrez, Source | actin related protein 2/3 complex, subunit 1A, 41kDa | 6519 | 0.037 | 0.2614 | No |
| 31 | ABL1 | NA | ABL1 Entrez, Source | v-abl Abelson murine leukemia viral oncogene homolog 1 | 6995 | -0.014 | 0.2274 | No |
| 32 | WASL | NA | WASL Entrez, Source | Wiskott-Aldrich syndrome-like | 7201 | -0.033 | 0.2136 | No |
| 33 | CDC42 | NA | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 7674 | -0.082 | 0.1821 | No |
| 34 | RHOA | NA | RHOA Entrez, Source | ras homolog gene family, member A | 8007 | -0.115 | 0.1618 | No |
| 35 | NCK1 | NA | NCK1 Entrez, Source | NCK adaptor protein 1 | 8954 | -0.220 | 0.1005 | No |
| 36 | ARPC1B | NA | ARPC1B Entrez, Source | actin related protein 2/3 complex, subunit 1B, 41kDa | 9220 | -0.252 | 0.0896 | No |
| 37 | NCK2 | NA | NCK2 Entrez, Source | NCK adaptor protein 2 | 9650 | -0.314 | 0.0689 | No |
| 38 | OCLN | NA | OCLN Entrez, Source | occludin | 9944 | -0.355 | 0.0594 | No |
| 39 | ITGB1 | NA | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 10722 | -0.479 | 0.0188 | No |
| 40 | CD14 | NA | CD14 Entrez, Source | CD14 molecule | 11218 | -0.567 | 0.0017 | No |
| 41 | TUBB6 | NA | TUBB6 Entrez, Source | tubulin, beta 6 | 11293 | -0.583 | 0.0156 | No |
| 42 | CTNNB1 | NA | CTNNB1 Entrez, Source | catenin (cadherin-associated protein), beta 1, 88kDa | 12021 | -0.762 | -0.0119 | No |
| 43 | PRKCA | NA | PRKCA Entrez, Source | protein kinase C, alpha | 12193 | -0.818 | 0.0027 | No |
| 44 | TUBB1 | NA | TUBB1 Entrez, Source | tubulin, beta 1 | 12336 | -0.868 | 0.0211 | No |
| 45 | FYN | NA | FYN Entrez, Source | FYN oncogene related to SRC, FGR, YES | 13049 | -1.256 | 0.0109 | No |
| 46 | TLR5 | NA | TLR5 Entrez, Source | toll-like receptor 5 | 13197 | -1.389 | 0.0462 | No |
