Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w6a_vs_wt_vs_wt.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp_repos |
| Phenotype | w6a_vs_wt.cls#ago1w6a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | KEGG_OXIDATIVE_PHOSPHORYLATION |
| Enrichment Score (ES) | -0.58611184 |
| Normalized Enrichment Score (NES) | -2.1944823 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ATP6V0D2 | NA | ATP6V0D2 Entrez, Source | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 | 770 | 1.036 | -0.0391 | No |
| 2 | COX6B2 | NA | COX6B2 Entrez, Source | cytochrome c oxidase subunit VIb polypeptide 2 (testis) | 879 | 0.955 | -0.0314 | No |
| 3 | ATP6V0A4 | NA | ATP6V0A4 Entrez, Source | ATPase, H+ transporting, lysosomal V0 subunit a4 | 1855 | 0.618 | -0.0923 | No |
| 4 | ATP6V1G1 | NA | ATP6V1G1 Entrez, Source | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | 1988 | 0.589 | -0.0923 | No |
| 5 | PPA1 | NA | PPA1 Entrez, Source | pyrophosphatase (inorganic) 1 | 2257 | 0.540 | -0.1030 | No |
| 6 | ATP6V0D1 | NA | ATP6V0D1 Entrez, Source | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 | 2464 | 0.506 | -0.1097 | No |
| 7 | ATP6V1H | NA | ATP6V1H Entrez, Source | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | 3683 | 0.335 | -0.1929 | No |
| 8 | ATP6V0A2 | NA | ATP6V0A2 Entrez, Source | ATPase, H+ transporting, lysosomal V0 subunit a2 | 4183 | 0.279 | -0.2247 | No |
| 9 | NDUFB10 | NA | NDUFB10 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa | 4360 | 0.259 | -0.2333 | No |
| 10 | ATP6V0C | NA | ATP6V0C Entrez, Source | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | 5094 | 0.182 | -0.2837 | No |
| 11 | ATP6V0B | NA | ATP6V0B Entrez, Source | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | 5119 | 0.180 | -0.2825 | No |
| 12 | ATP6V1C1 | NA | ATP6V1C1 Entrez, Source | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 5294 | 0.162 | -0.2925 | No |
| 13 | ATP6V1F | NA | ATP6V1F Entrez, Source | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F | 5299 | 0.162 | -0.2902 | No |
| 14 | ATP6V0E1 | NA | ATP6V0E1 Entrez, Source | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | 6079 | 0.079 | -0.3456 | No |
| 15 | ATP6V1B2 | NA | ATP6V1B2 Entrez, Source | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 | 6881 | -0.002 | -0.4039 | No |
| 16 | ATP5D | NA | ATP5D Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit | 7257 | -0.040 | -0.4306 | No |
| 17 | NDUFV3 | NA | NDUFV3 Entrez, Source | NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa | 7412 | -0.057 | -0.4408 | No |
| 18 | UQCR11 | NA | 7644 | -0.079 | -0.4564 | No | ||
| 19 | ATP6V1D | NA | ATP6V1D Entrez, Source | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 7759 | -0.091 | -0.4632 | No |
| 20 | NDUFB7 | NA | NDUFB7 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa | 7777 | -0.092 | -0.4629 | No |
| 21 | ATP6V1E1 | NA | ATP6V1E1 Entrez, Source | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 | 7862 | -0.100 | -0.4674 | No |
| 22 | NDUFB9 | NA | NDUFB9 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa | 7937 | -0.107 | -0.4710 | No |
| 23 | ATP6V0A1 | NA | ATP6V0A1 Entrez, Source | ATPase, H+ transporting, lysosomal V0 subunit a1 | 8071 | -0.123 | -0.4787 | No |
| 24 | ATP6V1C2 | NA | ATP6V1C2 Entrez, Source | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 | 8108 | -0.127 | -0.4793 | No |
| 25 | COX10 | NA | COX10 Entrez, Source | COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) | 8210 | -0.139 | -0.4843 | No |
| 26 | UQCRFS1 | NA | UQCRFS1 Entrez, Source | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | 8783 | -0.200 | -0.5227 | No |
| 27 | NDUFV2 | NA | NDUFV2 Entrez, Source | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 8825 | -0.206 | -0.5223 | No |
| 28 | NDUFA8 | NA | NDUFA8 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa | 9017 | -0.228 | -0.5325 | No |
| 29 | NDUFA11 | NA | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 9131 | -0.241 | -0.5368 | No |
| 30 | NDUFS7 | NA | NDUFS7 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | 9133 | -0.241 | -0.5329 | No |
| 31 | COX7A2L | NA | COX7A2L Entrez, Source | cytochrome c oxidase subunit VIIa polypeptide 2 like | 9489 | -0.293 | -0.5540 | No |
| 32 | NDUFB2 | NA | NDUFB2 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa | 9548 | -0.300 | -0.5533 | No |
| 33 | NDUFAB1 | NA | NDUFAB1 Entrez, Source | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa | 9593 | -0.305 | -0.5515 | No |
| 34 | COX17 | NA | COX17 Entrez, Source | COX17 cytochrome c oxidase assembly homolog (S. cerevisiae) | 9627 | -0.311 | -0.5489 | No |
| 35 | NDUFS8 | NA | NDUFS8 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) | 9879 | -0.348 | -0.5615 | No |
| 36 | NDUFS3 | NA | NDUFS3 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) | 9933 | -0.354 | -0.5595 | No |
| 37 | COX15 | NA | COX15 Entrez, Source | COX15 homolog, cytochrome c oxidase assembly protein (yeast) | 10161 | -0.387 | -0.5697 | No |
| 38 | NDUFA10 | NA | NDUFA10 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa | 10387 | -0.425 | -0.5792 | Yes |
| 39 | SDHB | NA | SDHB Entrez, Source | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | 10461 | -0.436 | -0.5774 | Yes |
| 40 | NDUFS4 | NA | NDUFS4 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 10470 | -0.437 | -0.5708 | Yes |
| 41 | COX5A | NA | COX5A Entrez, Source | cytochrome c oxidase subunit Va | 10523 | -0.445 | -0.5673 | Yes |
| 42 | ATP5C1 | NA | ATP5C1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 | 10643 | -0.467 | -0.5683 | Yes |
| 43 | UQCRC1 | NA | UQCRC1 Entrez, Source | ubiquinol-cytochrome c reductase core protein I | 10695 | -0.475 | -0.5643 | Yes |
| 44 | ATP5G3 | NA | ATP5G3 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) | 10759 | -0.485 | -0.5610 | Yes |
| 45 | COX4I1 | NA | COX4I1 Entrez, Source | cytochrome c oxidase subunit IV isoform 1 | 10760 | -0.485 | -0.5530 | Yes |
| 46 | ATP5I | NA | ATP5I Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E | 10863 | -0.504 | -0.5522 | Yes |
| 47 | SDHC | NA | SDHC Entrez, Source | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | 10930 | -0.514 | -0.5486 | Yes |
| 48 | ATP5G2 | NA | ATP5G2 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) | 10959 | -0.520 | -0.5422 | Yes |
| 49 | NDUFC2 | NA | NDUFC2 Entrez, Source | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa | 10967 | -0.521 | -0.5342 | Yes |
| 50 | ATP5L | NA | ATP5L Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit G | 10978 | -0.523 | -0.5263 | Yes |
| 51 | NDUFS6 | NA | NDUFS6 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) | 11041 | -0.535 | -0.5221 | Yes |
| 52 | COX11 | NA | COX11 Entrez, Source | COX11 homolog, cytochrome c oxidase assembly protein (yeast) | 11170 | -0.558 | -0.5223 | Yes |
| 53 | CYC1 | NA | CYC1 Entrez, Source | cytochrome c-1 | 11222 | -0.567 | -0.5167 | Yes |
| 54 | NDUFS5 | NA | NDUFS5 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) | 11285 | -0.582 | -0.5117 | Yes |
| 55 | ATP5H | NA | ATP5H Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d | 11314 | -0.588 | -0.5042 | Yes |
| 56 | ATP5J2 | NA | ATP5J2 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2 | 11369 | -0.597 | -0.4983 | Yes |
| 57 | NDUFA9 | NA | NDUFA9 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa | 11386 | -0.600 | -0.4897 | Yes |
| 58 | NDUFC1 | NA | NDUFC1 Entrez, Source | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa | 11496 | -0.623 | -0.4874 | Yes |
| 59 | UQCRQ | NA | UQCRQ Entrez, Source | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | 11614 | -0.653 | -0.4853 | Yes |
| 60 | NDUFS2 | NA | NDUFS2 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) | 11651 | -0.660 | -0.4771 | Yes |
| 61 | NDUFA3 | NA | NDUFA3 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa | 11706 | -0.672 | -0.4700 | Yes |
| 62 | NDUFA1 | NA | NDUFA1 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa | 11714 | -0.675 | -0.4595 | Yes |
| 63 | NDUFA6 | NA | NDUFA6 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa | 11745 | -0.684 | -0.4505 | Yes |
| 64 | ATP5O | NA | ATP5O Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) | 11766 | -0.689 | -0.4407 | Yes |
| 65 | COX6A1 | NA | COX6A1 Entrez, Source | cytochrome c oxidase subunit VIa polypeptide 1 | 11769 | -0.690 | -0.4296 | Yes |
| 66 | ATP5G1 | NA | ATP5G1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9) | 11772 | -0.691 | -0.4184 | Yes |
| 67 | COX6C | NA | COX6C Entrez, Source | cytochrome c oxidase subunit VIc | 11796 | -0.698 | -0.4087 | Yes |
| 68 | NDUFS1 | NA | NDUFS1 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 11893 | -0.722 | -0.4039 | Yes |
| 69 | ATP5B | NA | ATP5B Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide | 11967 | -0.744 | -0.3971 | Yes |
| 70 | NDUFB8 | NA | NDUFB8 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa | 12008 | -0.759 | -0.3876 | Yes |
| 71 | PPA2 | NA | PPA2 Entrez, Source | pyrophosphatase (inorganic) 2 | 12009 | -0.759 | -0.3751 | Yes |
| 72 | ATP5F1 | NA | ATP5F1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1 | 12053 | -0.772 | -0.3657 | Yes |
| 73 | NDUFA2 | NA | NDUFA2 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa | 12064 | -0.777 | -0.3537 | Yes |
| 74 | UQCR10 | NA | 12066 | -0.777 | -0.3411 | Yes | ||
| 75 | COX6B1 | NA | COX6B1 Entrez, Source | cytochrome c oxidase subunit Vib polypeptide 1 (ubiquitous) | 12086 | -0.781 | -0.3297 | Yes |
| 76 | NDUFB6 | NA | NDUFB6 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | 12106 | -0.789 | -0.3182 | Yes |
| 77 | NDUFA4 | NA | NDUFA4 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa | 12145 | -0.803 | -0.3078 | Yes |
| 78 | ATP6AP1 | NA | ATP6AP1 Entrez, Source | ATPase, H+ transporting, lysosomal accessory protein 1 | 12153 | -0.805 | -0.2952 | Yes |
| 79 | UQCRH | NA | UQCRH Entrez, Source | ubiquinol-cytochrome c reductase hinge protein | 12158 | -0.807 | -0.2823 | Yes |
| 80 | SDHD | NA | SDHD Entrez, Source | succinate dehydrogenase complex, subunit D, integral membrane protein | 12186 | -0.815 | -0.2709 | Yes |
| 81 | NDUFB3 | NA | NDUFB3 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa | 12187 | -0.815 | -0.2576 | Yes |
| 82 | NDUFV1 | NA | NDUFV1 Entrez, Source | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa | 12219 | -0.825 | -0.2463 | Yes |
| 83 | COX8A | NA | COX8A Entrez, Source | cytochrome c oxidase subunit 8A (ubiquitous) | 12241 | -0.834 | -0.2342 | Yes |
| 84 | ATP5J | NA | ATP5J Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6 | 12254 | -0.837 | -0.2214 | Yes |
| 85 | NDUFB4 | NA | NDUFB4 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa | 12267 | -0.842 | -0.2085 | Yes |
| 86 | NDUFA5 | NA | NDUFA5 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa | 12296 | -0.850 | -0.1967 | Yes |
| 87 | NDUFA7 | NA | NDUFA7 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa | 12408 | -0.895 | -0.1901 | Yes |
| 88 | COX7A2 | NA | COX7A2 Entrez, Source | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | 12409 | -0.895 | -0.1755 | Yes |
| 89 | ATP6V1A | NA | ATP6V1A Entrez, Source | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A | 12424 | -0.903 | -0.1618 | Yes |
| 90 | ATP5A1 | NA | ATP5A1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle | 12430 | -0.907 | -0.1473 | Yes |
| 91 | UQCRB | NA | UQCRB Entrez, Source | ubiquinol-cytochrome c reductase binding protein | 12456 | -0.921 | -0.1341 | Yes |
| 92 | NDUFA4L2 | NA | NDUFA4L2 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 12458 | -0.922 | -0.1191 | Yes |
| 93 | COX7C | NA | COX7C Entrez, Source | cytochrome c oxidase subunit VIIc | 12481 | -0.929 | -0.1055 | Yes |
| 94 | NDUFB1 | NA | NDUFB1 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa | 12642 | -1.007 | -0.1007 | Yes |
| 95 | SDHA | NA | SDHA Entrez, Source | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 12856 | -1.123 | -0.0978 | Yes |
| 96 | COX5B | NA | COX5B Entrez, Source | cytochrome c oxidase subunit Vb | 12858 | -1.125 | -0.0795 | Yes |
| 97 | NDUFB5 | NA | NDUFB5 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | 12869 | -1.132 | -0.0618 | Yes |
| 98 | TCIRG1 | NA | TCIRG1 Entrez, Source | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | 12974 | -1.198 | -0.0497 | Yes |
| 99 | COX7B | NA | COX7B Entrez, Source | cytochrome c oxidase subunit VIIb | 12976 | -1.199 | -0.0302 | Yes |
| 100 | UQCRC2 | NA | UQCRC2 Entrez, Source | ubiquinol-cytochrome c reductase core protein II | 12985 | -1.203 | -0.0111 | Yes |
| 101 | UQCRHL | NA | 12995 | -1.213 | 0.0080 | Yes | ||
| 102 | ATP6V1G2 | NA | ATP6V1G2 Entrez, Source | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 | 13328 | -1.550 | 0.0092 | Yes |
| 103 | LHPP | NA | LHPP Entrez, Source | - | 13422 | -1.687 | 0.0300 | Yes |
