Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w6a_vs_wt_vs_wt.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp_repos |
| Phenotype | w6a_vs_wt.cls#ago1w6a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | KEGG_OTHER_GLYCAN_DEGRADATION |
| Enrichment Score (ES) | -0.6265662 |
| Normalized Enrichment Score (NES) | -1.5719783 |
| Nominal p-value | 0.025408348 |
| FDR q-value | 0.093901895 |
| FWER p-Value | 0.762 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | NEU3 | NA | NEU3 Entrez, Source | sialidase 3 (membrane sialidase) | 6670 | 0.021 | -0.4803 | No |
| 2 | GBA | NA | GBA Entrez, Source | glucosidase, beta; acid (includes glucosylceramidase) | 8001 | -0.114 | -0.5640 | No |
| 3 | HEXB | NA | HEXB Entrez, Source | hexosaminidase B (beta polypeptide) | 8757 | -0.197 | -0.5970 | Yes |
| 4 | ENGASE | NA | 9060 | -0.233 | -0.5933 | Yes | ||
| 5 | NEU1 | NA | NEU1 Entrez, Source | sialidase 1 (lysosomal sialidase) | 9207 | -0.251 | -0.5763 | Yes |
| 6 | MAN2B2 | NA | MAN2B2 Entrez, Source | mannosidase, alpha, class 2B, member 2 | 9903 | -0.350 | -0.5881 | Yes |
| 7 | AGA | NA | AGA Entrez, Source | aspartylglucosaminidase | 10129 | -0.382 | -0.5624 | Yes |
| 8 | MAN2B1 | NA | MAN2B1 Entrez, Source | mannosidase, alpha, class 2B, member 1 | 10261 | -0.404 | -0.5274 | Yes |
| 9 | GLB1 | NA | GLB1 Entrez, Source | galactosidase, beta 1 | 10408 | -0.428 | -0.4910 | Yes |
| 10 | FUCA2 | NA | FUCA2 Entrez, Source | fucosidase, alpha-L- 2, plasma | 10918 | -0.512 | -0.4715 | Yes |
| 11 | HEXA | NA | HEXA Entrez, Source | hexosaminidase A (alpha polypeptide) | 11194 | -0.563 | -0.4295 | Yes |
| 12 | MAN2C1 | NA | MAN2C1 Entrez, Source | mannosidase, alpha, class 2C, member 1 | 12328 | -0.865 | -0.4165 | Yes |
| 13 | MANBA | NA | MANBA Entrez, Source | mannosidase, beta A, lysosomal | 12607 | -0.983 | -0.3285 | Yes |
| 14 | FUCA1 | NA | FUCA1 Entrez, Source | fucosidase, alpha-L- 1, tissue | 12896 | -1.146 | -0.2234 | Yes |
| 15 | NEU4 | NA | NEU4 Entrez, Source | sialidase 4 | 13719 | -2.650 | 0.0083 | Yes |
