Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w6a_vs_wt_vs_wt.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp_repos |
| Phenotype | w6a_vs_wt.cls#ago1w6a_versus_ago1gfp_repos |
| Upregulated in class | ago1w6a |
| GeneSet | KEGG_NICOTINATE_AND_NICOTINAMIDE_METABOLISM |
| Enrichment Score (ES) | 0.5714801 |
| Normalized Enrichment Score (NES) | 1.5417078 |
| Nominal p-value | 0.04585153 |
| FDR q-value | 0.14120977 |
| FWER p-Value | 0.751 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | NT5E | NA | NT5E Entrez, Source | 5'-nucleotidase, ecto (CD73) | 93 | 3.000 | 0.1985 | Yes |
| 2 | NMNAT2 | NA | NMNAT2 Entrez, Source | nicotinamide nucleotide adenylyltransferase 2 | 119 | 2.698 | 0.3813 | Yes |
| 3 | AOX1 | NA | AOX1 Entrez, Source | aldehyde oxidase 1 | 449 | 1.409 | 0.4539 | Yes |
| 4 | BST1 | NA | BST1 Entrez, Source | bone marrow stromal cell antigen 1 | 532 | 1.275 | 0.5352 | Yes |
| 5 | NT5C2 | NA | NT5C2 Entrez, Source | 5'-nucleotidase, cytosolic II | 1354 | 0.755 | 0.5274 | Yes |
| 6 | NAMPT | NA | 1439 | 0.734 | 0.5715 | Yes | ||
| 7 | PNP | NA | 2333 | 0.527 | 0.5429 | No | ||
| 8 | NMNAT1 | NA | NMNAT1 Entrez, Source | nicotinamide nucleotide adenylyltransferase 1 | 6600 | 0.028 | 0.2361 | No |
| 9 | ENPP1 | NA | ENPP1 Entrez, Source | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 6626 | 0.026 | 0.2361 | No |
| 10 | QPRT | NA | QPRT Entrez, Source | quinolinate phosphoribosyltransferase (nicotinate-nucleotide pyrophosphorylase (carboxylating)) | 6760 | 0.011 | 0.2272 | No |
| 11 | NADK | NA | NADK Entrez, Source | NAD kinase | 9881 | -0.348 | 0.0252 | No |
| 12 | NT5C | NA | NT5C Entrez, Source | 5', 3'-nucleotidase, cytosolic | 10275 | -0.406 | 0.0246 | No |
| 13 | NNMT | NA | NNMT Entrez, Source | nicotinamide N-methyltransferase | 10394 | -0.426 | 0.0452 | No |
| 14 | NT5M | NA | NT5M Entrez, Source | 5',3'-nucleotidase, mitochondrial | 10459 | -0.436 | 0.0704 | No |
| 15 | NUDT12 | NA | NUDT12 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 12 | 10774 | -0.488 | 0.0811 | No |
| 16 | NADSYN1 | NA | NADSYN1 Entrez, Source | NAD synthetase 1 | 10861 | -0.503 | 0.1093 | No |
| 17 | NNT | NA | NNT Entrez, Source | nicotinamide nucleotide transhydrogenase | 13325 | -1.547 | 0.0368 | No |
