Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w6a_vs_wt_vs_wt.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp_repos |
| Phenotype | w6a_vs_wt.cls#ago1w6a_versus_ago1gfp_repos |
| Upregulated in class | ago1w6a |
| GeneSet | KEGG_HEMATOPOIETIC_CELL_LINEAGE |
| Enrichment Score (ES) | 0.4071459 |
| Normalized Enrichment Score (NES) | 1.4059693 |
| Nominal p-value | 0.057788946 |
| FDR q-value | 0.21169999 |
| FWER p-Value | 0.971 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | IL7R | NA | IL7R Entrez, Source | interleukin 7 receptor | 3 | 4.680 | 0.0984 | Yes |
| 2 | IL6 | NA | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 15 | 4.383 | 0.1899 | Yes |
| 3 | ITGA2 | NA | ITGA2 Entrez, Source | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 192 | 2.266 | 0.2249 | Yes |
| 4 | CD44 | NA | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 336 | 1.659 | 0.2494 | Yes |
| 5 | CSF2RA | NA | CSF2RA Entrez, Source | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) | 378 | 1.539 | 0.2789 | Yes |
| 6 | ITGA5 | NA | ITGA5 Entrez, Source | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 390 | 1.519 | 0.3101 | Yes |
| 7 | IL1R1 | NA | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 560 | 1.229 | 0.3237 | Yes |
| 8 | ITGAM | NA | ITGAM Entrez, Source | integrin, alpha M (complement component 3 receptor 3 subunit) | 696 | 1.100 | 0.3371 | Yes |
| 9 | IL4R | NA | IL4R Entrez, Source | interleukin 4 receptor | 732 | 1.063 | 0.3569 | Yes |
| 10 | IL11 | NA | IL11 Entrez, Source | interleukin 11 | 773 | 1.035 | 0.3758 | Yes |
| 11 | IL1A | NA | IL1A Entrez, Source | interleukin 1, alpha | 977 | 0.904 | 0.3802 | Yes |
| 12 | ITGA3 | NA | ITGA3 Entrez, Source | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 1015 | 0.884 | 0.3961 | Yes |
| 13 | CD1D | NA | CD1D Entrez, Source | CD1d molecule | 1162 | 0.827 | 0.4029 | Yes |
| 14 | ITGA6 | NA | ITGA6 Entrez, Source | integrin, alpha 6 | 1327 | 0.764 | 0.4071 | Yes |
| 15 | ANPEP | NA | ANPEP Entrez, Source | alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150) | 1632 | 0.679 | 0.3994 | No |
| 16 | CD1A | NA | CD1A Entrez, Source | CD1a molecule | 2429 | 0.511 | 0.3524 | No |
| 17 | IL1B | NA | IL1B Entrez, Source | interleukin 1, beta | 2581 | 0.487 | 0.3517 | No |
| 18 | IL6R | NA | IL6R Entrez, Source | interleukin 6 receptor | 3094 | 0.409 | 0.3232 | No |
| 19 | IL9R | NA | IL9R Entrez, Source | interleukin 9 receptor | 3096 | 0.409 | 0.3317 | No |
| 20 | IL2RA | NA | IL2RA Entrez, Source | interleukin 2 receptor, alpha | 3404 | 0.367 | 0.3172 | No |
| 21 | CD55 | NA | CD55 Entrez, Source | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 3945 | 0.303 | 0.2844 | No |
| 22 | KIT | NA | KIT Entrez, Source | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 4009 | 0.296 | 0.2861 | No |
| 23 | IL5RA | NA | IL5RA Entrez, Source | interleukin 5 receptor, alpha | 4957 | 0.196 | 0.2215 | No |
| 24 | CD1C | NA | CD1C Entrez, Source | CD1c molecule | 5865 | 0.101 | 0.1579 | No |
| 25 | IL3RA | NA | IL3RA Entrez, Source | interleukin 3 receptor, alpha (low affinity) | 6957 | -0.010 | 0.0789 | No |
| 26 | ITGB3 | NA | ITGB3 Entrez, Source | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 7628 | -0.078 | 0.0320 | No |
| 27 | CD4 | NA | CD4 Entrez, Source | CD4 molecule | 7841 | -0.098 | 0.0187 | No |
| 28 | CD22 | NA | CD22 Entrez, Source | CD22 molecule | 8182 | -0.134 | -0.0032 | No |
| 29 | CD19 | NA | CD19 Entrez, Source | CD19 molecule | 9065 | -0.233 | -0.0622 | No |
| 30 | CD3G | NA | CD3G Entrez, Source | CD3g molecule, gamma (CD3-TCR complex) | 9937 | -0.355 | -0.1179 | No |
| 31 | CD59 | NA | CD59 Entrez, Source | CD59 molecule, complement regulatory protein | 10017 | -0.367 | -0.1159 | No |
| 32 | GP5 | NA | GP5 Entrez, Source | glycoprotein V (platelet) | 10095 | -0.378 | -0.1136 | No |
| 33 | GP9 | NA | GP9 Entrez, Source | glycoprotein IX (platelet) | 10872 | -0.505 | -0.1592 | No |
| 34 | TFRC | NA | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 10954 | -0.519 | -0.1542 | No |
| 35 | CR1 | NA | CR1 Entrez, Source | complement component (3b/4b) receptor 1 (Knops blood group) | 11207 | -0.565 | -0.1605 | No |
| 36 | CD14 | NA | CD14 Entrez, Source | CD14 molecule | 11218 | -0.567 | -0.1493 | No |
| 37 | KITLG | NA | KITLG Entrez, Source | KIT ligand | 11475 | -0.620 | -0.1548 | No |
| 38 | CD9 | NA | CD9 Entrez, Source | CD9 molecule | 11497 | -0.623 | -0.1432 | No |
| 39 | EPOR | NA | EPOR Entrez, Source | erythropoietin receptor | 11843 | -0.711 | -0.1533 | No |
| 40 | FLT3LG | NA | FLT3LG Entrez, Source | fms-related tyrosine kinase 3 ligand | 11849 | -0.712 | -0.1386 | No |
| 41 | CD37 | NA | CD37 Entrez, Source | CD37 molecule | 11892 | -0.722 | -0.1265 | No |
| 42 | ITGA1 | NA | ITGA1 Entrez, Source | integrin, alpha 1 | 11982 | -0.747 | -0.1172 | No |
| 43 | CD36 | NA | CD36 Entrez, Source | CD36 molecule (thrombospondin receptor) | 11998 | -0.756 | -0.1024 | No |
| 44 | THPO | NA | THPO Entrez, Source | thrombopoietin (myeloproliferative leukemia virus oncogene ligand, megakaryocyte growth and development factor) | 12365 | -0.879 | -0.1104 | No |
| 45 | CSF1R | NA | CSF1R Entrez, Source | colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog | 12807 | -1.094 | -0.1193 | No |
| 46 | GYPA | NA | GYPA Entrez, Source | glycophorin A (MNS blood group) | 12849 | -1.120 | -0.0987 | No |
| 47 | GP1BA | NA | GP1BA Entrez, Source | glycoprotein Ib (platelet), alpha polypeptide | 13339 | -1.568 | -0.1012 | No |
| 48 | MME | NA | MME Entrez, Source | membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase) | 13674 | -2.360 | -0.0757 | No |
| 49 | ITGA2B | NA | ITGA2B Entrez, Source | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) | 13815 | -4.140 | 0.0014 | No |
