Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w6a_vs_wt_vs_wt.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp_repos |
| Phenotype | w6a_vs_wt.cls#ago1w6a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | KEGG_GLYCOLYSIS_GLUCONEOGENESIS |
| Enrichment Score (ES) | -0.5370892 |
| Normalized Enrichment Score (NES) | -1.7484018 |
| Nominal p-value | 0.0033557047 |
| FDR q-value | 0.018600767 |
| FWER p-Value | 0.178 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | HK2 | NA | HK2 Entrez, Source | hexokinase 2 | 1786 | 0.636 | -0.1038 | No |
| 2 | PFKP | NA | PFKP Entrez, Source | phosphofructokinase, platelet | 2287 | 0.535 | -0.1184 | No |
| 3 | ALDH3A1 | NA | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 3480 | 0.356 | -0.1904 | No |
| 4 | ALDH1A3 | NA | ALDH1A3 Entrez, Source | aldehyde dehydrogenase 1 family, member A3 | 3877 | 0.313 | -0.2065 | No |
| 5 | PGM2 | NA | PGM2 Entrez, Source | phosphoglucomutase 2 | 4772 | 0.214 | -0.2627 | No |
| 6 | ALDH1B1 | NA | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 5084 | 0.183 | -0.2778 | No |
| 7 | ADH1B | NA | ADH1B Entrez, Source | alcohol dehydrogenase IB (class I), beta polypeptide | 5649 | 0.122 | -0.3138 | No |
| 8 | ALDOA | NA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 5880 | 0.100 | -0.3264 | No |
| 9 | PGAM1 | NA | PGAM1 Entrez, Source | phosphoglycerate mutase 1 (brain) | 6191 | 0.068 | -0.3462 | No |
| 10 | LDHA | NA | LDHA Entrez, Source | lactate dehydrogenase A | 6424 | 0.047 | -0.3611 | No |
| 11 | G6PC | NA | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 6941 | -0.009 | -0.3982 | No |
| 12 | LDHAL6A | NA | LDHAL6A Entrez, Source | lactate dehydrogenase A-like 6A | 6986 | -0.013 | -0.4009 | No |
| 13 | FBP1 | NA | FBP1 Entrez, Source | fructose-1,6-bisphosphatase 1 | 7096 | -0.022 | -0.4079 | No |
| 14 | PFKM | NA | PFKM Entrez, Source | phosphofructokinase, muscle | 7219 | -0.035 | -0.4153 | No |
| 15 | ADH5 | NA | ADH5 Entrez, Source | alcohol dehydrogenase 5 (class III), chi polypeptide | 7549 | -0.071 | -0.4363 | No |
| 16 | ENO1 | NA | ENO1 Entrez, Source | enolase 1, (alpha) | 8327 | -0.149 | -0.4866 | No |
| 17 | GAPDH | NA | GAPDH Entrez, Source | glyceraldehyde-3-phosphate dehydrogenase | 8442 | -0.162 | -0.4883 | No |
| 18 | BPGM | NA | BPGM Entrez, Source | 2,3-bisphosphoglycerate mutase | 8541 | -0.172 | -0.4885 | No |
| 19 | DLAT | NA | DLAT Entrez, Source | dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) | 8620 | -0.182 | -0.4868 | No |
| 20 | GPI | NA | GPI Entrez, Source | glucose phosphate isomerase | 9315 | -0.265 | -0.5264 | Yes |
| 21 | TPI1 | NA | TPI1 Entrez, Source | triosephosphate isomerase 1 | 9395 | -0.278 | -0.5209 | Yes |
| 22 | PGAM2 | NA | PGAM2 Entrez, Source | phosphoglycerate mutase 2 (muscle) | 9462 | -0.288 | -0.5140 | Yes |
| 23 | ADH4 | NA | ADH4 Entrez, Source | alcohol dehydrogenase 4 (class II), pi polypeptide | 9477 | -0.290 | -0.5033 | Yes |
| 24 | GALM | NA | GALM Entrez, Source | galactose mutarotase (aldose 1-epimerase) | 9554 | -0.301 | -0.4966 | Yes |
| 25 | ALDH3A2 | NA | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 9636 | -0.312 | -0.4899 | Yes |
| 26 | FBP2 | NA | FBP2 Entrez, Source | fructose-1,6-bisphosphatase 2 | 9701 | -0.321 | -0.4815 | Yes |
| 27 | DLD | NA | DLD Entrez, Source | dihydrolipoamide dehydrogenase | 9719 | -0.325 | -0.4696 | Yes |
| 28 | PDHA1 | NA | PDHA1 Entrez, Source | pyruvate dehydrogenase (lipoamide) alpha 1 | 9820 | -0.339 | -0.4632 | Yes |
| 29 | LDHB | NA | LDHB Entrez, Source | lactate dehydrogenase B | 10486 | -0.440 | -0.4936 | Yes |
| 30 | PGK1 | NA | PGK1 Entrez, Source | phosphoglycerate kinase 1 | 10801 | -0.493 | -0.4965 | Yes |
| 31 | ENO2 | NA | ENO2 Entrez, Source | enolase 2 (gamma, neuronal) | 10819 | -0.496 | -0.4777 | Yes |
| 32 | ALDH9A1 | NA | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 10955 | -0.519 | -0.4665 | Yes |
| 33 | ACSS2 | NA | ACSS2 Entrez, Source | acyl-CoA synthetase short-chain family member 2 | 11071 | -0.540 | -0.4529 | Yes |
| 34 | LDHAL6B | NA | LDHAL6B Entrez, Source | lactate dehydrogenase A-like 6B | 11102 | -0.547 | -0.4330 | Yes |
| 35 | PGM1 | NA | PGM1 Entrez, Source | phosphoglucomutase 1 | 11686 | -0.669 | -0.4482 | Yes |
| 36 | AKR1A1 | NA | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 11855 | -0.713 | -0.4316 | Yes |
| 37 | ALDH7A1 | NA | ALDH7A1 Entrez, Source | aldehyde dehydrogenase 7 family, member A1 | 12010 | -0.760 | -0.4120 | Yes |
| 38 | PDHB | NA | PDHB Entrez, Source | pyruvate dehydrogenase (lipoamide) beta | 12302 | -0.852 | -0.3987 | Yes |
| 39 | HK1 | NA | HK1 Entrez, Source | hexokinase 1 | 12755 | -1.065 | -0.3884 | Yes |
| 40 | PGAM4 | NA | PGAM4 Entrez, Source | phosphoglycerate mutase family member 4 | 12861 | -1.130 | -0.3503 | Yes |
| 41 | PCK2 | NA | PCK2 Entrez, Source | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 12963 | -1.192 | -0.3094 | Yes |
| 42 | ALDH2 | NA | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 13109 | -1.302 | -0.2673 | Yes |
| 43 | ALDH3B1 | NA | ALDH3B1 Entrez, Source | aldehyde dehydrogenase 3 family, member B1 | 13265 | -1.473 | -0.2190 | Yes |
| 44 | PFKL | NA | PFKL Entrez, Source | phosphofructokinase, liver | 13274 | -1.484 | -0.1595 | Yes |
| 45 | ALDOC | NA | ALDOC Entrez, Source | aldolase C, fructose-bisphosphate | 13596 | -2.047 | -0.1000 | Yes |
| 46 | ENO3 | NA | ENO3 Entrez, Source | enolase 3 (beta, muscle) | 13755 | -2.899 | 0.0057 | Yes |
