Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w6a_vs_wt_vs_wt.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp_repos |
| Phenotype | w6a_vs_wt.cls#ago1w6a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | KEGG_FATTY_ACID_METABOLISM |
| Enrichment Score (ES) | -0.5737494 |
| Normalized Enrichment Score (NES) | -1.7901266 |
| Nominal p-value | 0.0016501651 |
| FDR q-value | 0.014302936 |
| FWER p-Value | 0.113 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ACSL4 | NA | ACSL4 Entrez, Source | acyl-CoA synthetase long-chain family member 4 | 3026 | 0.418 | -0.1985 | No |
| 2 | ACSL5 | NA | ACSL5 Entrez, Source | acyl-CoA synthetase long-chain family member 5 | 4128 | 0.284 | -0.2641 | No |
| 3 | CPT1A | NA | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 4433 | 0.250 | -0.2737 | No |
| 4 | CPT1B | NA | CPT1B Entrez, Source | carnitine palmitoyltransferase 1B (muscle) | 5074 | 0.184 | -0.3109 | No |
| 5 | ALDH1B1 | NA | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 5084 | 0.183 | -0.3025 | No |
| 6 | ADH1B | NA | ADH1B Entrez, Source | alcohol dehydrogenase IB (class I), beta polypeptide | 5649 | 0.122 | -0.3373 | No |
| 7 | CYP4A11 | NA | CYP4A11 Entrez, Source | cytochrome P450, family 4, subfamily A, polypeptide 11 | 6797 | 0.007 | -0.4201 | No |
| 8 | ADH5 | NA | ADH5 Entrez, Source | alcohol dehydrogenase 5 (class III), chi polypeptide | 7549 | -0.071 | -0.4710 | No |
| 9 | ACAA1 | NA | ACAA1 Entrez, Source | acetyl-Coenzyme A acyltransferase 1 (peroxisomal 3-oxoacyl-Coenzyme A thiolase) | 8688 | -0.190 | -0.5440 | No |
| 10 | ACSL3 | NA | ACSL3 Entrez, Source | acyl-CoA synthetase long-chain family member 3 | 8881 | -0.212 | -0.5474 | No |
| 11 | ACSL6 | NA | ACSL6 Entrez, Source | acyl-CoA synthetase long-chain family member 6 | 9191 | -0.248 | -0.5574 | Yes |
| 12 | CPT2 | NA | CPT2 Entrez, Source | carnitine palmitoyltransferase II | 9235 | -0.255 | -0.5479 | Yes |
| 13 | ADH4 | NA | ADH4 Entrez, Source | alcohol dehydrogenase 4 (class II), pi polypeptide | 9477 | -0.290 | -0.5509 | Yes |
| 14 | ACOX3 | NA | ACOX3 Entrez, Source | acyl-Coenzyme A oxidase 3, pristanoyl | 9583 | -0.304 | -0.5433 | Yes |
| 15 | ALDH3A2 | NA | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 9636 | -0.312 | -0.5316 | Yes |
| 16 | ECI2 | NA | 10219 | -0.397 | -0.5540 | Yes | ||
| 17 | ACADVL | NA | ACADVL Entrez, Source | acyl-Coenzyme A dehydrogenase, very long chain | 10279 | -0.407 | -0.5380 | Yes |
| 18 | ACAA2 | NA | ACAA2 Entrez, Source | acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) | 10640 | -0.466 | -0.5409 | Yes |
| 19 | EHHADH | NA | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 10749 | -0.483 | -0.5247 | Yes |
| 20 | CPT1C | NA | CPT1C Entrez, Source | carnitine palmitoyltransferase 1C | 10840 | -0.500 | -0.5063 | Yes |
| 21 | ALDH9A1 | NA | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 10955 | -0.519 | -0.4887 | Yes |
| 22 | ACADSB | NA | ACADSB Entrez, Source | acyl-Coenzyme A dehydrogenase, short/branched chain | 11149 | -0.553 | -0.4752 | Yes |
| 23 | HADHB | NA | HADHB Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 11304 | -0.585 | -0.4572 | Yes |
| 24 | HADH | NA | HADH Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase | 11456 | -0.615 | -0.4376 | Yes |
| 25 | ACOX1 | NA | ACOX1 Entrez, Source | acyl-Coenzyme A oxidase 1, palmitoyl | 11472 | -0.619 | -0.4078 | Yes |
| 26 | GCDH | NA | GCDH Entrez, Source | glutaryl-Coenzyme A dehydrogenase | 11682 | -0.668 | -0.3897 | Yes |
| 27 | ECHS1 | NA | ECHS1 Entrez, Source | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 11963 | -0.742 | -0.3731 | Yes |
| 28 | ALDH7A1 | NA | ALDH7A1 Entrez, Source | aldehyde dehydrogenase 7 family, member A1 | 12010 | -0.760 | -0.3386 | Yes |
| 29 | ACADM | NA | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 12101 | -0.786 | -0.3060 | Yes |
| 30 | ECI1 | NA | 12174 | -0.813 | -0.2708 | Yes | ||
| 31 | HADHA | NA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 12220 | -0.825 | -0.2329 | Yes |
| 32 | ACAT2 | NA | ACAT2 Entrez, Source | acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase) | 12819 | -1.099 | -0.2216 | Yes |
| 33 | ACADS | NA | ACADS Entrez, Source | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 12961 | -1.190 | -0.1726 | Yes |
| 34 | ALDH2 | NA | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 13109 | -1.302 | -0.1184 | Yes |
| 35 | ACAT1 | NA | ACAT1 Entrez, Source | acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) | 13202 | -1.396 | -0.0556 | Yes |
| 36 | ACSL1 | NA | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 13590 | -2.037 | 0.0177 | Yes |
