Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w6a_vs_wt_vs_wt.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp_repos |
| Phenotype | w6a_vs_wt.cls#ago1w6a_versus_ago1gfp_repos |
| Upregulated in class | ago1w6a |
| GeneSet | KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION |
| Enrichment Score (ES) | 0.3718784 |
| Normalized Enrichment Score (NES) | 1.3444369 |
| Nominal p-value | 0.08060453 |
| FDR q-value | 0.29247367 |
| FWER p-Value | 0.995 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CCL5 | NA | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 10 | 4.462 | 0.1221 | Yes |
| 2 | JUN | NA | JUN Entrez, Source | jun oncogene | 236 | 1.996 | 0.1608 | Yes |
| 3 | MAP3K14 | NA | MAP3K14 Entrez, Source | mitogen-activated protein kinase kinase kinase 14 | 246 | 1.972 | 0.2144 | Yes |
| 4 | HBEGF | NA | HBEGF Entrez, Source | heparin-binding EGF-like growth factor | 319 | 1.713 | 0.2564 | Yes |
| 5 | PLCG2 | NA | PLCG2 Entrez, Source | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 361 | 1.581 | 0.2969 | Yes |
| 6 | EGFR | NA | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 637 | 1.150 | 0.3086 | Yes |
| 7 | ATP6V0D2 | NA | ATP6V0D2 Entrez, Source | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 | 770 | 1.036 | 0.3276 | Yes |
| 8 | CSK | NA | CSK Entrez, Source | c-src tyrosine kinase | 1191 | 0.815 | 0.3195 | Yes |
| 9 | SRC | NA | SRC Entrez, Source | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 1469 | 0.724 | 0.3194 | Yes |
| 10 | NFKBIA | NA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 1484 | 0.721 | 0.3382 | Yes |
| 11 | RELA | NA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 1570 | 0.698 | 0.3512 | Yes |
| 12 | ATP6V0A4 | NA | ATP6V0A4 Entrez, Source | ATPase, H+ transporting, lysosomal V0 subunit a4 | 1855 | 0.618 | 0.3476 | Yes |
| 13 | ATP6V1G1 | NA | ATP6V1G1 Entrez, Source | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | 1988 | 0.589 | 0.3543 | Yes |
| 14 | NFKB1 | NA | NFKB1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 2004 | 0.585 | 0.3693 | Yes |
| 15 | IKBKG | NA | IKBKG Entrez, Source | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 2396 | 0.517 | 0.3551 | Yes |
| 16 | ATP6V0D1 | NA | ATP6V0D1 Entrez, Source | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 | 2464 | 0.506 | 0.3642 | Yes |
| 17 | CASP3 | NA | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 2546 | 0.492 | 0.3719 | Yes |
| 18 | MAPK8 | NA | MAPK8 Entrez, Source | mitogen-activated protein kinase 8 | 2742 | 0.461 | 0.3704 | No |
| 19 | CHUK | NA | CHUK Entrez, Source | conserved helix-loop-helix ubiquitous kinase | 2997 | 0.421 | 0.3636 | No |
| 20 | ADAM17 | NA | ADAM17 Entrez, Source | ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme) | 3315 | 0.381 | 0.3510 | No |
| 21 | JAM2 | NA | JAM2 Entrez, Source | junctional adhesion molecule 2 | 3358 | 0.375 | 0.3583 | No |
| 22 | LYN | NA | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 3567 | 0.347 | 0.3527 | No |
| 23 | ATP6V1H | NA | ATP6V1H Entrez, Source | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | 3683 | 0.335 | 0.3536 | No |
| 24 | GIT1 | NA | GIT1 Entrez, Source | G protein-coupled receptor kinase interactor 1 | 4108 | 0.286 | 0.3307 | No |
| 25 | ATP6V0A2 | NA | ATP6V0A2 Entrez, Source | ATPase, H+ transporting, lysosomal V0 subunit a2 | 4183 | 0.279 | 0.3330 | No |
| 26 | PAK1 | NA | PAK1 Entrez, Source | p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) | 4258 | 0.271 | 0.3351 | No |
| 27 | TJP1 | NA | TJP1 Entrez, Source | tight junction protein 1 (zona occludens 1) | 4633 | 0.229 | 0.3143 | No |
| 28 | ATP6V0C | NA | ATP6V0C Entrez, Source | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | 5094 | 0.182 | 0.2859 | No |
| 29 | ATP6V0B | NA | ATP6V0B Entrez, Source | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | 5119 | 0.180 | 0.2891 | No |
| 30 | ADAM10 | NA | ADAM10 Entrez, Source | ADAM metallopeptidase domain 10 | 5165 | 0.175 | 0.2906 | No |
| 31 | ATP6V1C1 | NA | ATP6V1C1 Entrez, Source | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 5294 | 0.162 | 0.2858 | No |
| 32 | ATP6V1F | NA | ATP6V1F Entrez, Source | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F | 5299 | 0.162 | 0.2900 | No |
| 33 | MAP2K4 | NA | MAP2K4 Entrez, Source | mitogen-activated protein kinase kinase 4 | 5370 | 0.154 | 0.2891 | No |
| 34 | RAC1 | NA | RAC1 Entrez, Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 5556 | 0.134 | 0.2794 | No |
| 35 | PTPN11 | NA | PTPN11 Entrez, Source | protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) | 5619 | 0.125 | 0.2783 | No |
| 36 | MET | NA | MET Entrez, Source | met proto-oncogene (hepatocyte growth factor receptor) | 5916 | 0.096 | 0.2595 | No |
| 37 | ATP6V0E1 | NA | ATP6V0E1 Entrez, Source | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | 6079 | 0.079 | 0.2499 | No |
| 38 | ATP6V1B2 | NA | ATP6V1B2 Entrez, Source | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 | 6881 | -0.002 | 0.1918 | No |
| 39 | JAM3 | NA | JAM3 Entrez, Source | junctional adhesion molecule 3 | 7360 | -0.052 | 0.1585 | No |
| 40 | MAPK14 | NA | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 7577 | -0.073 | 0.1448 | No |
| 41 | NOD1 | NA | 7612 | -0.077 | 0.1445 | No | ||
| 42 | CDC42 | NA | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 7674 | -0.082 | 0.1423 | No |
| 43 | ATP6V1D | NA | ATP6V1D Entrez, Source | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 7759 | -0.091 | 0.1387 | No |
| 44 | ATP6V1E1 | NA | ATP6V1E1 Entrez, Source | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 | 7862 | -0.100 | 0.1340 | No |
| 45 | ATP6V0A1 | NA | ATP6V0A1 Entrez, Source | ATPase, H+ transporting, lysosomal V0 subunit a1 | 8071 | -0.123 | 0.1223 | No |
| 46 | ATP6V1C2 | NA | ATP6V1C2 Entrez, Source | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 | 8108 | -0.127 | 0.1232 | No |
| 47 | PLCG1 | NA | PLCG1 Entrez, Source | phospholipase C, gamma 1 | 8316 | -0.148 | 0.1122 | No |
| 48 | MAPK12 | NA | MAPK12 Entrez, Source | mitogen-activated protein kinase 12 | 9483 | -0.292 | 0.0356 | No |
| 49 | MAPK9 | NA | MAPK9 Entrez, Source | mitogen-activated protein kinase 9 | 9823 | -0.340 | 0.0203 | No |
| 50 | IKBKB | NA | IKBKB Entrez, Source | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 9844 | -0.344 | 0.0284 | No |
| 51 | MAPK10 | NA | MAPK10 Entrez, Source | mitogen-activated protein kinase 10 | 10142 | -0.384 | 0.0174 | No |
| 52 | MAPK11 | NA | MAPK11 Entrez, Source | mitogen-activated protein kinase 11 | 10697 | -0.475 | -0.0098 | No |
| 53 | MAPK13 | NA | MAPK13 Entrez, Source | mitogen-activated protein kinase 13 | 10850 | -0.502 | -0.0070 | No |
| 54 | IGSF5 | NA | IGSF5 Entrez, Source | immunoglobulin superfamily, member 5 | 10990 | -0.526 | -0.0026 | No |
| 55 | PTPRZ1 | NA | PTPRZ1 Entrez, Source | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 11012 | -0.531 | 0.0105 | No |
| 56 | ATP6AP1 | NA | ATP6AP1 Entrez, Source | ATPase, H+ transporting, lysosomal accessory protein 1 | 12153 | -0.805 | -0.0501 | No |
| 57 | CXCR2 | NA | 12322 | -0.862 | -0.0385 | No | ||
| 58 | ATP6V1A | NA | ATP6V1A Entrez, Source | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A | 12424 | -0.903 | -0.0210 | No |
| 59 | TCIRG1 | NA | TCIRG1 Entrez, Source | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | 12974 | -1.198 | -0.0279 | No |
| 60 | ATP6V1G2 | NA | ATP6V1G2 Entrez, Source | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 | 13328 | -1.550 | -0.0108 | No |
| 61 | F11R | NA | F11R Entrez, Source | F11 receptor | 13441 | -1.725 | 0.0285 | No |
