Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w6a_vs_wt_vs_wt.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp_repos |
| Phenotype | w6a_vs_wt.cls#ago1w6a_versus_ago1gfp_repos |
| Upregulated in class | ago1w6a |
| GeneSet | KEGG_ECM_RECEPTOR_INTERACTION |
| Enrichment Score (ES) | 0.34339643 |
| Normalized Enrichment Score (NES) | 1.2788095 |
| Nominal p-value | 0.08791209 |
| FDR q-value | 0.33698022 |
| FWER p-Value | 0.999 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | THBS1 | NA | THBS1 Entrez, Source | thrombospondin 1 | 81 | 3.120 | 0.0396 | Yes |
| 2 | LAMA4 | NA | LAMA4 Entrez, Source | laminin, alpha 4 | 103 | 2.927 | 0.0807 | Yes |
| 3 | COL5A3 | NA | COL5A3 Entrez, Source | collagen, type V, alpha 3 | 139 | 2.572 | 0.1156 | Yes |
| 4 | SDC4 | NA | SDC4 Entrez, Source | syndecan 4 (amphiglycan, ryudocan) | 149 | 2.503 | 0.1514 | Yes |
| 5 | ITGA10 | NA | ITGA10 Entrez, Source | integrin, alpha 10 | 164 | 2.415 | 0.1856 | Yes |
| 6 | ITGA2 | NA | ITGA2 Entrez, Source | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 192 | 2.266 | 0.2166 | Yes |
| 7 | LAMC2 | NA | LAMC2 Entrez, Source | laminin, gamma 2 | 260 | 1.931 | 0.2399 | Yes |
| 8 | ITGB4 | NA | ITGB4 Entrez, Source | integrin, beta 4 | 327 | 1.696 | 0.2598 | Yes |
| 9 | CD44 | NA | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 336 | 1.659 | 0.2834 | Yes |
| 10 | ITGA5 | NA | ITGA5 Entrez, Source | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 390 | 1.519 | 0.3016 | Yes |
| 11 | TNXB | NA | TNXB Entrez, Source | tenascin XB | 415 | 1.484 | 0.3215 | Yes |
| 12 | ITGB6 | NA | ITGB6 Entrez, Source | integrin, beta 6 | 456 | 1.396 | 0.3389 | Yes |
| 13 | ITGB8 | NA | ITGB8 Entrez, Source | integrin, beta 8 | 628 | 1.160 | 0.3434 | Yes |
| 14 | VWF | NA | VWF Entrez, Source | von Willebrand factor | 919 | 0.933 | 0.3359 | No |
| 15 | ITGA3 | NA | ITGA3 Entrez, Source | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 1015 | 0.884 | 0.3419 | No |
| 16 | ITGA6 | NA | ITGA6 Entrez, Source | integrin, alpha 6 | 1327 | 0.764 | 0.3304 | No |
| 17 | COL6A1 | NA | COL6A1 Entrez, Source | collagen, type VI, alpha 1 | 2131 | 0.564 | 0.2803 | No |
| 18 | COL4A2 | NA | COL4A2 Entrez, Source | collagen, type IV, alpha 2 | 2271 | 0.538 | 0.2780 | No |
| 19 | COL4A1 | NA | COL4A1 Entrez, Source | collagen, type IV, alpha 1 | 2408 | 0.514 | 0.2756 | No |
| 20 | ITGA8 | NA | ITGA8 Entrez, Source | integrin, alpha 8 | 3756 | 0.327 | 0.1826 | No |
| 21 | TNC | NA | TNC Entrez, Source | tenascin C (hexabrachion) | 4457 | 0.248 | 0.1353 | No |
| 22 | COL2A1 | NA | COL2A1 Entrez, Source | collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) | 5037 | 0.188 | 0.0960 | No |
| 23 | SDC1 | NA | SDC1 Entrez, Source | syndecan 1 | 5389 | 0.152 | 0.0727 | No |
| 24 | AGRN | NA | 5397 | 0.151 | 0.0744 | No | ||
| 25 | LAMA5 | NA | LAMA5 Entrez, Source | laminin, alpha 5 | 5549 | 0.134 | 0.0654 | No |
| 26 | ITGB7 | NA | ITGB7 Entrez, Source | integrin, beta 7 | 5713 | 0.115 | 0.0552 | No |
| 27 | COL11A1 | NA | COL11A1 Entrez, Source | collagen, type XI, alpha 1 | 5734 | 0.113 | 0.0554 | No |
| 28 | FN1 | NA | FN1 Entrez, Source | fibronectin 1 | 6142 | 0.073 | 0.0269 | No |
| 29 | LAMB3 | NA | LAMB3 Entrez, Source | laminin, beta 3 | 6357 | 0.054 | 0.0121 | No |
| 30 | LAMA2 | NA | LAMA2 Entrez, Source | laminin, alpha 2 (merosin, congenital muscular dystrophy) | 6420 | 0.047 | 0.0083 | No |
| 31 | COL5A1 | NA | COL5A1 Entrez, Source | collagen, type V, alpha 1 | 6499 | 0.039 | 0.0032 | No |
| 32 | LAMC1 | NA | LAMC1 Entrez, Source | laminin, gamma 1 (formerly LAMB2) | 6862 | 0.001 | -0.0231 | No |
| 33 | LAMB1 | NA | LAMB1 Entrez, Source | laminin, beta 1 | 6938 | -0.008 | -0.0284 | No |
| 34 | ITGAV | NA | ITGAV Entrez, Source | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 7059 | -0.019 | -0.0369 | No |
| 35 | LAMA1 | NA | LAMA1 Entrez, Source | laminin, alpha 1 | 7314 | -0.046 | -0.0546 | No |
| 36 | ITGB3 | NA | ITGB3 Entrez, Source | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 7628 | -0.078 | -0.0762 | No |
| 37 | COL6A3 | NA | COL6A3 Entrez, Source | collagen, type VI, alpha 3 | 7823 | -0.097 | -0.0889 | No |
| 38 | ITGB5 | NA | ITGB5 Entrez, Source | integrin, beta 5 | 7873 | -0.102 | -0.0910 | No |
| 39 | HMMR | NA | HMMR Entrez, Source | hyaluronan-mediated motility receptor (RHAMM) | 8010 | -0.115 | -0.0992 | No |
| 40 | SV2A | NA | SV2A Entrez, Source | synaptic vesicle glycoprotein 2A | 8780 | -0.200 | -0.1522 | No |
| 41 | COL4A6 | NA | COL4A6 Entrez, Source | collagen, type IV, alpha 6 | 9256 | -0.258 | -0.1829 | No |
| 42 | THBS4 | NA | THBS4 Entrez, Source | thrombospondin 4 | 9288 | -0.261 | -0.1814 | No |
| 43 | DAG1 | NA | DAG1 Entrez, Source | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 9334 | -0.268 | -0.1807 | No |
| 44 | LAMC3 | NA | LAMC3 Entrez, Source | laminin, gamma 3 | 9430 | -0.283 | -0.1835 | No |
| 45 | TNN | NA | TNN Entrez, Source | tenascin N | 9624 | -0.310 | -0.1930 | No |
| 46 | GP5 | NA | GP5 Entrez, Source | glycoprotein V (platelet) | 10095 | -0.378 | -0.2217 | No |
| 47 | ITGB1 | NA | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 10722 | -0.479 | -0.2602 | No |
| 48 | HSPG2 | NA | HSPG2 Entrez, Source | heparan sulfate proteoglycan 2 (perlecan) | 10831 | -0.499 | -0.2607 | No |
| 49 | GP9 | NA | GP9 Entrez, Source | glycoprotein IX (platelet) | 10872 | -0.505 | -0.2563 | No |
| 50 | SV2B | NA | SV2B Entrez, Source | synaptic vesicle glycoprotein 2B | 11044 | -0.536 | -0.2609 | No |
| 51 | SV2C | NA | SV2C Entrez, Source | synaptic vesicle glycoprotein 2C | 11661 | -0.664 | -0.2960 | No |
| 52 | GP6 | NA | GP6 Entrez, Source | glycoprotein VI (platelet) | 11795 | -0.696 | -0.2955 | No |
| 53 | COL11A2 | NA | COL11A2 Entrez, Source | collagen, type XI, alpha 2 | 11979 | -0.746 | -0.2979 | No |
| 54 | ITGA1 | NA | ITGA1 Entrez, Source | integrin, alpha 1 | 11982 | -0.747 | -0.2872 | No |
| 55 | CD36 | NA | CD36 Entrez, Source | CD36 molecule (thrombospondin receptor) | 11998 | -0.756 | -0.2773 | No |
| 56 | CD47 | NA | CD47 Entrez, Source | CD47 molecule | 12103 | -0.788 | -0.2734 | No |
| 57 | SDC3 | NA | SDC3 Entrez, Source | syndecan 3 (N-syndecan) | 12261 | -0.839 | -0.2725 | No |
| 58 | COL6A6 | NA | 12346 | -0.872 | -0.2659 | No | ||
| 59 | ITGA7 | NA | ITGA7 Entrez, Source | integrin, alpha 7 | 12379 | -0.885 | -0.2554 | No |
| 60 | CHAD | NA | CHAD Entrez, Source | chondroadherin | 12380 | -0.886 | -0.2425 | No |
| 61 | COL5A2 | NA | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 12707 | -1.040 | -0.2510 | No |
| 62 | THBS3 | NA | THBS3 Entrez, Source | thrombospondin 3 | 12840 | -1.116 | -0.2443 | No |
| 63 | LAMA3 | NA | LAMA3 Entrez, Source | laminin, alpha 3 | 13132 | -1.319 | -0.2463 | No |
| 64 | SDC2 | NA | SDC2 Entrez, Source | syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan) | 13234 | -1.433 | -0.2327 | No |
| 65 | GP1BA | NA | GP1BA Entrez, Source | glycoprotein Ib (platelet), alpha polypeptide | 13339 | -1.568 | -0.2174 | No |
| 66 | LAMB2 | NA | LAMB2 Entrez, Source | laminin, beta 2 (laminin S) | 13365 | -1.595 | -0.1960 | No |
| 67 | COL4A4 | NA | COL4A4 Entrez, Source | collagen, type IV, alpha 4 | 13626 | -2.159 | -0.1835 | No |
| 68 | COL1A1 | NA | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 13723 | -2.670 | -0.1515 | No |
| 69 | VTN | NA | VTN Entrez, Source | vitronectin | 13776 | -3.164 | -0.1092 | No |
| 70 | COL3A1 | NA | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 13796 | -3.638 | -0.0576 | No |
| 71 | ITGA2B | NA | ITGA2B Entrez, Source | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) | 13815 | -4.140 | 0.0014 | No |
