Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w6a_vs_wt_vs_wt.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp_repos |
| Phenotype | w6a_vs_wt.cls#ago1w6a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | HALLMARK_PANCREAS_BETA_CELLS |
| Enrichment Score (ES) | -0.4283058 |
| Normalized Enrichment Score (NES) | -1.1713259 |
| Nominal p-value | 0.25466892 |
| FDR q-value | 0.26453212 |
| FWER p-Value | 0.997 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | VDR | NA | VDR Entrez, Source | vitamin D (1,25- dihydroxyvitamin D3) receptor | 570 | 1.219 | 0.0420 | No |
| 2 | ISL1 | NA | ISL1 Entrez, Source | ISL1 transcription factor, LIM/homeodomain, (islet-1) | 984 | 0.902 | 0.0736 | No |
| 3 | LMO2 | NA | LMO2 Entrez, Source | LIM domain only 2 (rhombotin-like 1) | 1657 | 0.673 | 0.0709 | No |
| 4 | HNF1A | NA | 1831 | 0.625 | 0.1011 | No | ||
| 5 | SRPRB | NA | SRPRB Entrez, Source | signal recognition particle receptor, B subunit | 2862 | 0.441 | 0.0566 | No |
| 6 | FOXA2 | NA | FOXA2 Entrez, Source | forkhead box A2 | 4089 | 0.289 | -0.0124 | No |
| 7 | SYT13 | NA | SYT13 Entrez, Source | synaptotagmin XIII | 6050 | 0.082 | -0.1487 | No |
| 8 | FOXO1 | NA | 6097 | 0.077 | -0.1468 | No | ||
| 9 | IAPP | NA | IAPP Entrez, Source | islet amyloid polypeptide | 6798 | 0.006 | -0.1970 | No |
| 10 | DCX | NA | DCX Entrez, Source | doublecortex; lissencephaly, X-linked (doublecortin) | 8843 | -0.207 | -0.3308 | No |
| 11 | PDX1 | NA | 9320 | -0.267 | -0.3471 | No | ||
| 12 | SPCS1 | NA | SPCS1 Entrez, Source | signal peptidase complex subunit 1 homolog (S. cerevisiae) | 10192 | -0.393 | -0.3834 | No |
| 13 | ELP4 | NA | ELP4 Entrez, Source | elongation protein 4 homolog (S. cerevisiae) | 10814 | -0.495 | -0.3945 | Yes |
| 14 | SEC11A | NA | 10986 | -0.526 | -0.3710 | Yes | ||
| 15 | SRP9 | NA | SRP9 Entrez, Source | signal recognition particle 9kDa | 11578 | -0.642 | -0.3699 | Yes |
| 16 | SRP14 | NA | SRP14 Entrez, Source | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 11579 | -0.642 | -0.3261 | Yes |
| 17 | PAX6 | NA | PAX6 Entrez, Source | paired box gene 6 (aniridia, keratitis) | 11966 | -0.744 | -0.3033 | Yes |
| 18 | STXBP1 | NA | STXBP1 Entrez, Source | syntaxin binding protein 1 | 12679 | -1.026 | -0.2848 | Yes |
| 19 | AKT3 | NA | AKT3 Entrez, Source | v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) | 13407 | -1.667 | -0.2236 | Yes |
| 20 | PCSK1 | NA | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 13463 | -1.754 | -0.1079 | Yes |
| 21 | MAFB | NA | MAFB Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) | 13562 | -1.972 | 0.0197 | Yes |
