Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w6a_vs_wt_vs_wt.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp_repos |
| Phenotype | w6a_vs_wt.cls#ago1w6a_versus_ago1gfp_repos |
| Upregulated in class | ago1w6a |
| GeneSet | HALLMARK_MYC_TARGETS_V2 |
| Enrichment Score (ES) | 0.52526736 |
| Normalized Enrichment Score (NES) | 1.9365718 |
| Nominal p-value | 0.0 |
| FDR q-value | 7.1372546E-4 |
| FWER p-Value | 0.003 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | NIP7 | NA | NIP7 Entrez, Source | nuclear import 7 homolog (S. cerevisiae) | 651 | 1.138 | -0.0102 | Yes |
| 2 | SRM | NA | SRM Entrez, Source | spermidine synthase | 679 | 1.115 | 0.0241 | Yes |
| 3 | UTP20 | NA | UTP20 Entrez, Source | UTP20, small subunit (SSU) processome component, homolog (yeast) | 717 | 1.081 | 0.0566 | Yes |
| 4 | RRP9 | NA | 779 | 1.031 | 0.0857 | Yes | ||
| 5 | GRWD1 | NA | GRWD1 Entrez, Source | glutamate-rich WD repeat containing 1 | 814 | 0.997 | 0.1157 | Yes |
| 6 | RRP12 | NA | 887 | 0.950 | 0.1413 | Yes | ||
| 7 | NOP2 | NA | 916 | 0.936 | 0.1698 | Yes | ||
| 8 | WDR43 | NA | WDR43 Entrez, Source | WD repeat domain 43 | 947 | 0.923 | 0.1976 | Yes |
| 9 | BYSL | NA | BYSL Entrez, Source | bystin-like | 1007 | 0.891 | 0.2223 | Yes |
| 10 | PPRC1 | NA | PPRC1 Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator-related 1 | 1048 | 0.872 | 0.2478 | Yes |
| 11 | TCOF1 | NA | TCOF1 Entrez, Source | Treacher Collins-Franceschetti syndrome 1 | 1145 | 0.833 | 0.2679 | Yes |
| 12 | NOLC1 | NA | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 1149 | 0.830 | 0.2947 | Yes |
| 13 | NOP16 | NA | 1249 | 0.794 | 0.3134 | Yes | ||
| 14 | MRTO4 | NA | 1382 | 0.748 | 0.3282 | Yes | ||
| 15 | SLC19A1 | NA | SLC19A1 Entrez, Source | solute carrier family 19 (folate transporter), member 1 | 1427 | 0.736 | 0.3489 | Yes |
| 16 | PES1 | NA | PES1 Entrez, Source | pescadillo homolog 1, containing BRCT domain (zebrafish) | 1429 | 0.736 | 0.3728 | Yes |
| 17 | MYBBP1A | NA | MYBBP1A Entrez, Source | MYB binding protein (P160) 1a | 1437 | 0.735 | 0.3962 | Yes |
| 18 | NOC4L | NA | NOC4L Entrez, Source | nucleolar complex associated 4 homolog (S. cerevisiae) | 1578 | 0.695 | 0.4087 | Yes |
| 19 | IMP4 | NA | IMP4 Entrez, Source | IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) | 1755 | 0.642 | 0.4168 | Yes |
| 20 | PLK1 | NA | PLK1 Entrez, Source | polo-like kinase 1 (Drosophila) | 1774 | 0.638 | 0.4362 | Yes |
| 21 | HK2 | NA | HK2 Entrez, Source | hexokinase 2 | 1786 | 0.636 | 0.4562 | Yes |
| 22 | RCL1 | NA | RCL1 Entrez, Source | RNA terminal phosphate cyclase-like 1 | 2088 | 0.571 | 0.4529 | Yes |
| 23 | RABEPK | NA | RABEPK Entrez, Source | Rab9 effector protein with kelch motifs | 2130 | 0.564 | 0.4683 | Yes |
| 24 | NOP56 | NA | 2191 | 0.552 | 0.4819 | Yes | ||
| 25 | IPO4 | NA | IPO4 Entrez, Source | importin 4 | 2195 | 0.551 | 0.4996 | Yes |
| 26 | WDR74 | NA | WDR74 Entrez, Source | WD repeat domain 74 | 2296 | 0.534 | 0.5097 | Yes |
| 27 | PA2G4 | NA | PA2G4 Entrez, Source | proliferation-associated 2G4, 38kDa | 2480 | 0.503 | 0.5128 | Yes |
| 28 | FARSA | NA | 2531 | 0.496 | 0.5253 | Yes | ||
| 29 | LAS1L | NA | LAS1L Entrez, Source | LAS1-like (S. cerevisiae) | 3032 | 0.417 | 0.5026 | No |
| 30 | DDX18 | NA | DDX18 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 3134 | 0.403 | 0.5083 | No |
| 31 | PPAN | NA | PPAN Entrez, Source | peter pan homolog (Drosophila) | 3228 | 0.390 | 0.5143 | No |
| 32 | MPHOSPH10 | NA | MPHOSPH10 Entrez, Source | M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) | 3463 | 0.359 | 0.5090 | No |
| 33 | HSPD1 | NA | HSPD1 Entrez, Source | heat shock 60kDa protein 1 (chaperonin) | 3528 | 0.351 | 0.5157 | No |
| 34 | NDUFAF4 | NA | 3934 | 0.304 | 0.4962 | No | ||
| 35 | HSPE1 | NA | HSPE1 Entrez, Source | heat shock 10kDa protein 1 (chaperonin 10) | 4145 | 0.283 | 0.4902 | No |
| 36 | PUS1 | NA | PUS1 Entrez, Source | pseudouridylate synthase 1 | 4308 | 0.264 | 0.4870 | No |
| 37 | NPM1 | NA | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 4781 | 0.214 | 0.4597 | No |
| 38 | DCTPP1 | NA | 4796 | 0.212 | 0.4656 | No | ||
| 39 | PRMT3 | NA | PRMT3 Entrez, Source | protein arginine methyltransferase 3 | 4797 | 0.212 | 0.4725 | No |
| 40 | SUPV3L1 | NA | SUPV3L1 Entrez, Source | suppressor of var1, 3-like 1 (S. cerevisiae) | 4846 | 0.207 | 0.4758 | No |
| 41 | CDK4 | NA | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 5046 | 0.187 | 0.4674 | No |
| 42 | PLK4 | NA | PLK4 Entrez, Source | polo-like kinase 4 (Drosophila) | 5899 | 0.098 | 0.4088 | No |
| 43 | MAP3K6 | NA | MAP3K6 Entrez, Source | mitogen-activated protein kinase kinase kinase 6 | 5946 | 0.093 | 0.4084 | No |
| 44 | GNL3 | NA | GNL3 Entrez, Source | guanine nucleotide binding protein-like 3 (nucleolar) | 6148 | 0.072 | 0.3962 | No |
| 45 | PHB | NA | PHB Entrez, Source | prohibitin | 6681 | 0.020 | 0.3582 | No |
| 46 | TBRG4 | NA | TBRG4 Entrez, Source | transforming growth factor beta regulator 4 | 6996 | -0.014 | 0.3359 | No |
| 47 | AIMP2 | NA | 7609 | -0.076 | 0.2939 | No | ||
| 48 | SORD | NA | SORD Entrez, Source | sorbitol dehydrogenase | 7660 | -0.081 | 0.2929 | No |
| 49 | CBX3 | NA | CBX3 Entrez, Source | chromobox homolog 3 (HP1 gamma homolog, Drosophila) | 7896 | -0.104 | 0.2793 | No |
| 50 | TMEM97 | NA | TMEM97 Entrez, Source | transmembrane protein 97 | 8392 | -0.157 | 0.2484 | No |
| 51 | EXOSC5 | NA | EXOSC5 Entrez, Source | exosome component 5 | 8618 | -0.181 | 0.2380 | No |
| 52 | TFB2M | NA | TFB2M Entrez, Source | transcription factor B2, mitochondrial | 9025 | -0.229 | 0.2160 | No |
| 53 | MYC | NA | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 9860 | -0.346 | 0.1667 | No |
| 54 | MCM4 | NA | MCM4 Entrez, Source | MCM4 minichromosome maintenance deficient 4 (S. cerevisiae) | 10015 | -0.366 | 0.1674 | No |
| 55 | SLC29A2 | NA | SLC29A2 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 2 | 10245 | -0.402 | 0.1639 | No |
| 56 | MCM5 | NA | MCM5 Entrez, Source | MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) | 11408 | -0.607 | 0.0993 | No |
| 57 | UNG | NA | UNG Entrez, Source | uracil-DNA glycosylase | 11992 | -0.753 | 0.0815 | No |
| 58 | DUSP2 | NA | DUSP2 Entrez, Source | dual specificity phosphatase 2 | 13368 | -1.602 | 0.0338 | No |
