Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w6a_vs_wt_vs_wt.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp.w6a_vs_wt.cls #ago1w6a_versus_ago1gfp_repos |
| Phenotype | w6a_vs_wt.cls#ago1w6a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | HALLMARK_ANGIOGENESIS |
| Enrichment Score (ES) | -0.36352125 |
| Normalized Enrichment Score (NES) | -1.0709678 |
| Nominal p-value | 0.3714789 |
| FDR q-value | 0.40541324 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | TNFRSF21 | NA | TNFRSF21 Entrez, Source | tumor necrosis factor receptor superfamily, member 21 | 130 | 2.631 | 0.0959 | No |
| 2 | OLR1 | NA | OLR1 Entrez, Source | oxidised low density lipoprotein (lectin-like) receptor 1 | 209 | 2.171 | 0.1771 | No |
| 3 | FSTL1 | NA | FSTL1 Entrez, Source | follistatin-like 1 | 373 | 1.548 | 0.2273 | No |
| 4 | JAG1 | NA | JAG1 Entrez, Source | jagged 1 (Alagille syndrome) | 432 | 1.447 | 0.2810 | No |
| 5 | THBD | NA | THBD Entrez, Source | thrombomodulin | 1044 | 0.873 | 0.2716 | No |
| 6 | NRP1 | NA | NRP1 Entrez, Source | neuropilin 1 | 1103 | 0.850 | 0.3014 | No |
| 7 | FGFR1 | NA | FGFR1 Entrez, Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 1516 | 0.711 | 0.3001 | No |
| 8 | JAG2 | NA | JAG2 Entrez, Source | jagged 2 | 2112 | 0.567 | 0.2797 | No |
| 9 | VAV2 | NA | VAV2 Entrez, Source | vav 2 oncogene | 3835 | 0.317 | 0.1676 | No |
| 10 | TIMP1 | NA | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 4124 | 0.284 | 0.1582 | No |
| 11 | MSX1 | NA | MSX1 Entrez, Source | msh homeobox homolog 1 (Drosophila) | 4265 | 0.271 | 0.1588 | No |
| 12 | PDGFA | NA | PDGFA Entrez, Source | platelet-derived growth factor alpha polypeptide | 4294 | 0.267 | 0.1675 | No |
| 13 | VCAN | NA | 6056 | 0.081 | 0.0432 | No | ||
| 14 | APP | NA | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 6652 | 0.022 | 0.0010 | No |
| 15 | ITGAV | NA | ITGAV Entrez, Source | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 7059 | -0.019 | -0.0276 | No |
| 16 | VEGFA | NA | 7811 | -0.096 | -0.0782 | No | ||
| 17 | PTK2 | NA | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 8268 | -0.144 | -0.1055 | No |
| 18 | STC1 | NA | STC1 Entrez, Source | stanniocalcin 1 | 8647 | -0.185 | -0.1254 | No |
| 19 | PRG2 | NA | PRG2 Entrez, Source | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 8875 | -0.212 | -0.1334 | No |
| 20 | CCND2 | NA | CCND2 Entrez, Source | cyclin D2 | 8965 | -0.222 | -0.1310 | No |
| 21 | LRPAP1 | NA | LRPAP1 Entrez, Source | low density lipoprotein receptor-related protein associated protein 1 | 10123 | -0.381 | -0.1995 | No |
| 22 | S100A4 | NA | S100A4 Entrez, Source | S100 calcium binding protein A4 | 10515 | -0.444 | -0.2101 | No |
| 23 | LPL | NA | LPL Entrez, Source | lipoprotein lipase | 12381 | -0.886 | -0.3097 | Yes |
| 24 | COL5A2 | NA | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 12707 | -1.040 | -0.2916 | Yes |
| 25 | LUM | NA | LUM Entrez, Source | lumican | 13701 | -2.519 | -0.2627 | Yes |
| 26 | VTN | NA | VTN Entrez, Source | vitronectin | 13776 | -3.164 | -0.1415 | Yes |
| 27 | COL3A1 | NA | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 13796 | -3.638 | 0.0028 | Yes |
