Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w1a_vs_wt_vs_wt.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp_repos |
| Phenotype | w1a_vs_wt.cls#ago1w1a_versus_ago1gfp_repos |
| Upregulated in class | ago1w1a |
| GeneSet | KEGG_PROTEASOME |
| Enrichment Score (ES) | 0.5343472 |
| Normalized Enrichment Score (NES) | 1.6762705 |
| Nominal p-value | 0.008347246 |
| FDR q-value | 0.04083873 |
| FWER p-Value | 0.368 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PSMB9 | NA | PSMB9 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) | 147 | 2.721 | 0.1344 | Yes |
| 2 | PSMB10 | NA | PSMB10 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 10 | 480 | 1.569 | 0.1982 | Yes |
| 3 | PSME1 | NA | PSME1 Entrez, Source | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 1049 | 1.096 | 0.2243 | Yes |
| 4 | PSMD6 | NA | PSMD6 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 1408 | 0.944 | 0.2540 | Yes |
| 5 | PSMA6 | NA | PSMA6 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 6 | 1565 | 0.891 | 0.2920 | Yes |
| 6 | PSME2 | NA | PSME2 Entrez, Source | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 1613 | 0.878 | 0.3354 | Yes |
| 7 | PSMC4 | NA | PSMC4 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 1804 | 0.830 | 0.3684 | Yes |
| 8 | PSMD8 | NA | PSMD8 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 1960 | 0.796 | 0.4015 | Yes |
| 9 | PSMA5 | NA | PSMA5 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 5 | 2783 | 0.632 | 0.3893 | Yes |
| 10 | PSME3 | NA | PSME3 Entrez, Source | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) | 3000 | 0.596 | 0.4086 | Yes |
| 11 | PSMD3 | NA | PSMD3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 3079 | 0.585 | 0.4349 | Yes |
| 12 | PSMC3 | NA | PSMC3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 3811 | 0.484 | 0.4199 | Yes |
| 13 | PSMB7 | NA | PSMB7 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 7 | 3824 | 0.483 | 0.4445 | Yes |
| 14 | PSMD12 | NA | PSMD12 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 3849 | 0.481 | 0.4683 | Yes |
| 15 | PSMD1 | NA | PSMD1 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 3981 | 0.463 | 0.4854 | Yes |
| 16 | PSMD2 | NA | PSMD2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 4092 | 0.448 | 0.5027 | Yes |
| 17 | PSMD11 | NA | PSMD11 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 4252 | 0.428 | 0.5164 | Yes |
| 18 | PSMB2 | NA | PSMB2 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 2 | 4544 | 0.398 | 0.5211 | Yes |
| 19 | PSMC1 | NA | PSMC1 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | 4772 | 0.376 | 0.5283 | Yes |
| 20 | PSMC5 | NA | PSMC5 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | 5170 | 0.334 | 0.5239 | Yes |
| 21 | PSMC2 | NA | PSMC2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | 5289 | 0.324 | 0.5343 | Yes |
| 22 | PSMD14 | NA | PSMD14 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 5818 | 0.276 | 0.5197 | No |
| 23 | PSMB11 | NA | 6063 | 0.258 | 0.5197 | No | ||
| 24 | PSMD13 | NA | PSMD13 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 6918 | 0.186 | 0.4823 | No |
| 25 | PSMB6 | NA | PSMB6 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 6 | 7036 | 0.177 | 0.4852 | No |
| 26 | PSMA8 | NA | PSMA8 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 8 | 7041 | 0.177 | 0.4942 | No |
| 27 | POMP | NA | POMP Entrez, Source | proteasome maturation protein | 7540 | 0.141 | 0.4742 | No |
| 28 | PSMA1 | NA | PSMA1 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 1 | 7595 | 0.136 | 0.4783 | No |
| 29 | PSMA3 | NA | PSMA3 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 3 | 7625 | 0.135 | 0.4838 | No |
| 30 | PSMF1 | NA | PSMF1 Entrez, Source | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 7744 | 0.127 | 0.4839 | No |
| 31 | PSMC6 | NA | PSMC6 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 8066 | 0.102 | 0.4715 | No |
| 32 | PSMA4 | NA | PSMA4 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 4 | 8238 | 0.091 | 0.4669 | No |
| 33 | PSMB4 | NA | PSMB4 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 4 | 8358 | 0.082 | 0.4646 | No |
| 34 | PSMD7 | NA | PSMD7 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog) | 8434 | 0.077 | 0.4644 | No |
| 35 | PSMD4 | NA | PSMD4 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 8528 | 0.070 | 0.4630 | No |
| 36 | PSMA7 | NA | PSMA7 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 7 | 8547 | 0.068 | 0.4655 | No |
| 37 | PSME4 | NA | PSME4 Entrez, Source | proteasome (prosome, macropain) activator subunit 4 | 10415 | -0.043 | 0.3648 | No |
| 38 | PSMB5 | NA | PSMB5 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 5 | 10422 | -0.044 | 0.3668 | No |
| 39 | PSMB3 | NA | PSMB3 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 3 | 11089 | -0.083 | 0.3344 | No |
| 40 | PSMA2 | NA | PSMA2 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 2 | 11331 | -0.101 | 0.3263 | No |
| 41 | PSMB1 | NA | PSMB1 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 1 | 11933 | -0.150 | 0.3010 | No |
| 42 | PSMB8 | NA | PSMB8 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 14436 | -0.397 | 0.1838 | No |
| 43 | IFNG | NA | IFNG Entrez, Source | interferon, gamma | 14617 | -0.420 | 0.1959 | No |
