Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w1a_vs_wt_vs_wt.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp_repos |
| Phenotype | w1a_vs_wt.cls#ago1w1a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | KEGG_PROPANOATE_METABOLISM |
| Enrichment Score (ES) | -0.58471155 |
| Normalized Enrichment Score (NES) | -1.8184313 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.012175261 |
| FWER p-Value | 0.088 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | LDHAL6B | NA | LDHAL6B Entrez, Source | lactate dehydrogenase A-like 6B | 3846 | 0.481 | -0.1836 | No |
| 2 | MLYCD | NA | MLYCD Entrez, Source | malonyl-CoA decarboxylase | 5093 | 0.342 | -0.2320 | No |
| 3 | LDHAL6A | NA | LDHAL6A Entrez, Source | lactate dehydrogenase A-like 6A | 6991 | 0.181 | -0.3259 | No |
| 4 | ACSS2 | NA | ACSS2 Entrez, Source | acyl-CoA synthetase short-chain family member 2 | 7022 | 0.178 | -0.3170 | No |
| 5 | ACSS3 | NA | 7333 | 0.157 | -0.3248 | No | ||
| 6 | ACACB | NA | ACACB Entrez, Source | acetyl-Coenzyme A carboxylase beta | 8150 | 0.096 | -0.3641 | No |
| 7 | LDHA | NA | LDHA Entrez, Source | lactate dehydrogenase A | 11836 | -0.143 | -0.5588 | No |
| 8 | ALDH1B1 | NA | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 11847 | -0.144 | -0.5509 | No |
| 9 | ACSS1 | NA | ACSS1 Entrez, Source | acyl-CoA synthetase short-chain family member 1 | 12088 | -0.163 | -0.5545 | No |
| 10 | SUCLA2 | NA | SUCLA2 Entrez, Source | succinate-CoA ligase, ADP-forming, beta subunit | 12175 | -0.171 | -0.5490 | No |
| 11 | HIBCH | NA | HIBCH Entrez, Source | 3-hydroxyisobutyryl-Coenzyme A hydrolase | 12823 | -0.228 | -0.5712 | Yes |
| 12 | LDHC | NA | LDHC Entrez, Source | lactate dehydrogenase C | 12974 | -0.243 | -0.5651 | Yes |
| 13 | ALDH7A1 | NA | ALDH7A1 Entrez, Source | aldehyde dehydrogenase 7 family, member A1 | 13180 | -0.261 | -0.5609 | Yes |
| 14 | ECHS1 | NA | ECHS1 Entrez, Source | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 13439 | -0.286 | -0.5582 | Yes |
| 15 | ACAT2 | NA | ACAT2 Entrez, Source | acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase) | 13792 | -0.320 | -0.5587 | Yes |
| 16 | ALDH9A1 | NA | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 13994 | -0.345 | -0.5493 | Yes |
| 17 | SUCLG2 | NA | SUCLG2 Entrez, Source | succinate-CoA ligase, GDP-forming, beta subunit | 14250 | -0.373 | -0.5413 | Yes |
| 18 | ALDH3A2 | NA | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 14517 | -0.407 | -0.5318 | Yes |
| 19 | PCCB | NA | PCCB Entrez, Source | propionyl Coenzyme A carboxylase, beta polypeptide | 15012 | -0.477 | -0.5308 | Yes |
| 20 | LDHB | NA | LDHB Entrez, Source | lactate dehydrogenase B | 15651 | -0.581 | -0.5315 | Yes |
| 21 | MCEE | NA | MCEE Entrez, Source | methylmalonyl CoA epimerase | 15857 | -0.622 | -0.5059 | Yes |
| 22 | MUT | NA | MUT Entrez, Source | methylmalonyl Coenzyme A mutase | 16077 | -0.674 | -0.4780 | Yes |
| 23 | EHHADH | NA | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 16508 | -0.801 | -0.4543 | Yes |
| 24 | ACACA | NA | ACACA Entrez, Source | acetyl-Coenzyme A carboxylase alpha | 16537 | -0.808 | -0.4079 | Yes |
| 25 | SUCLG1 | NA | SUCLG1 Entrez, Source | succinate-CoA ligase, GDP-forming, alpha subunit | 16597 | -0.825 | -0.3622 | Yes |
| 26 | ALDH2 | NA | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 16658 | -0.842 | -0.3156 | Yes |
| 27 | HADHA | NA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 16783 | -0.880 | -0.2703 | Yes |
| 28 | PCCA | NA | PCCA Entrez, Source | propionyl Coenzyme A carboxylase, alpha polypeptide | 17004 | -0.969 | -0.2250 | Yes |
| 29 | ACADM | NA | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 17198 | -1.057 | -0.1730 | Yes |
| 30 | ALDH6A1 | NA | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 17307 | -1.122 | -0.1124 | Yes |
| 31 | ABAT | NA | ABAT Entrez, Source | 4-aminobutyrate aminotransferase | 17441 | -1.211 | -0.0480 | Yes |
| 32 | ACAT1 | NA | ACAT1 Entrez, Source | acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) | 17713 | -1.484 | 0.0250 | Yes |
