Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w1a_vs_wt_vs_wt.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp_repos |
| Phenotype | w1a_vs_wt.cls#ago1w1a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | KEGG_OXIDATIVE_PHOSPHORYLATION |
| Enrichment Score (ES) | -0.5567263 |
| Normalized Enrichment Score (NES) | -2.1951826 |
| Nominal p-value | 0.0 |
| FDR q-value | 5.3125E-4 |
| FWER p-Value | 0.001 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | COX6B2 | NA | COX6B2 Entrez, Source | cytochrome c oxidase subunit VIb polypeptide 2 (testis) | 273 | 2.087 | 0.0179 | No |
| 2 | PPA1 | NA | PPA1 Entrez, Source | pyrophosphatase (inorganic) 1 | 1549 | 0.896 | -0.0385 | No |
| 3 | ATP5D | NA | ATP5D Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit | 1832 | 0.822 | -0.0412 | No |
| 4 | ATP6V0D1 | NA | ATP6V0D1 Entrez, Source | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 | 1966 | 0.794 | -0.0360 | No |
| 5 | ATP6V1C2 | NA | ATP6V1C2 Entrez, Source | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 | 3184 | 0.569 | -0.0944 | No |
| 6 | NDUFB7 | NA | NDUFB7 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa | 3283 | 0.554 | -0.0910 | No |
| 7 | ATP6V0A2 | NA | ATP6V0A2 Entrez, Source | ATPase, H+ transporting, lysosomal V0 subunit a2 | 3508 | 0.521 | -0.0952 | No |
| 8 | ATP6V0C | NA | ATP6V0C Entrez, Source | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | 4013 | 0.460 | -0.1158 | No |
| 9 | ATP6V0B | NA | ATP6V0B Entrez, Source | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | 4369 | 0.414 | -0.1289 | No |
| 10 | ATP4A | NA | ATP4A Entrez, Source | ATPase, H+/K+ exchanging, alpha polypeptide | 4407 | 0.410 | -0.1245 | No |
| 11 | NDUFS8 | NA | NDUFS8 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) | 4581 | 0.395 | -0.1278 | No |
| 12 | ATP6V0E2 | NA | ATP6V0E2 Entrez, Source | ATPase, H+ transporting V0 subunit e2 | 4813 | 0.371 | -0.1347 | No |
| 13 | ATP6V1H | NA | ATP6V1H Entrez, Source | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | 5266 | 0.326 | -0.1546 | No |
| 14 | COX7A1 | NA | COX7A1 Entrez, Source | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | 5681 | 0.288 | -0.1730 | No |
| 15 | NDUFV3 | NA | NDUFV3 Entrez, Source | NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa | 5751 | 0.282 | -0.1724 | No |
| 16 | ATP6V1G1 | NA | ATP6V1G1 Entrez, Source | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | 5872 | 0.272 | -0.1747 | No |
| 17 | NDUFB10 | NA | NDUFB10 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa | 5951 | 0.266 | -0.1748 | No |
| 18 | NDUFS7 | NA | NDUFS7 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | 6279 | 0.238 | -0.1892 | No |
| 19 | NDUFA11 | NA | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 6434 | 0.226 | -0.1941 | No |
| 20 | UQCR11 | NA | 7511 | 0.144 | -0.2514 | No | ||
| 21 | ATP6V0A1 | NA | ATP6V0A1 Entrez, Source | ATPase, H+ transporting, lysosomal V0 subunit a1 | 8034 | 0.105 | -0.2787 | No |
| 22 | ATP6V0A4 | NA | ATP6V0A4 Entrez, Source | ATPase, H+ transporting, lysosomal V0 subunit a4 | 8309 | 0.085 | -0.2925 | No |
| 23 | ATP6V0D2 | NA | ATP6V0D2 Entrez, Source | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 | 8341 | 0.083 | -0.2929 | No |
| 24 | ATP6V1F | NA | ATP6V1F Entrez, Source | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F | 9293 | 0.015 | -0.3454 | No |
| 25 | ATP12A | NA | ATP12A Entrez, Source | ATPase, H+/K+ transporting, nongastric, alpha polypeptide | 9349 | 0.011 | -0.3482 | No |
| 26 | COX8C | NA | COX8C Entrez, Source | cytochrome c oxidase subunit 8C | 9478 | 0.003 | -0.3553 | No |
| 27 | COX4I2 | NA | COX4I2 Entrez, Source | cytochrome c oxidase subunit IV isoform 2 (lung) | 9626 | 0.000 | -0.3634 | No |
| 28 | NDUFS6 | NA | NDUFS6 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) | 9787 | -0.005 | -0.3722 | No |
| 29 | ATP6V1C1 | NA | ATP6V1C1 Entrez, Source | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 10089 | -0.025 | -0.3885 | No |
| 30 | ATP6V0E1 | NA | ATP6V0E1 Entrez, Source | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | 10451 | -0.045 | -0.4078 | No |
| 31 | COX10 | NA | COX10 Entrez, Source | COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) | 10644 | -0.057 | -0.4175 | No |
| 32 | NDUFB9 | NA | NDUFB9 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa | 11657 | -0.128 | -0.4715 | No |
| 33 | ATP6V1E1 | NA | ATP6V1E1 Entrez, Source | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 | 11672 | -0.129 | -0.4703 | No |
| 34 | NDUFV2 | NA | NDUFV2 Entrez, Source | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 12646 | -0.214 | -0.5208 | No |
| 35 | CYC1 | NA | CYC1 Entrez, Source | cytochrome c-1 | 12899 | -0.235 | -0.5310 | No |
| 36 | ATP6V1D | NA | ATP6V1D Entrez, Source | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 12946 | -0.240 | -0.5297 | No |
| 37 | NDUFB2 | NA | NDUFB2 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa | 13224 | -0.265 | -0.5409 | No |
| 38 | ATP6V1A | NA | ATP6V1A Entrez, Source | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A | 13230 | -0.265 | -0.5370 | No |
| 39 | COX7A2L | NA | COX7A2L Entrez, Source | cytochrome c oxidase subunit VIIa polypeptide 2 like | 13373 | -0.279 | -0.5404 | No |
| 40 | ATP5I | NA | ATP5I Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E | 13481 | -0.290 | -0.5418 | No |
| 41 | SDHC | NA | SDHC Entrez, Source | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | 13605 | -0.301 | -0.5438 | No |
| 42 | ATP5G2 | NA | ATP5G2 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) | 13780 | -0.318 | -0.5484 | No |
| 43 | NDUFA6 | NA | NDUFA6 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa | 13931 | -0.335 | -0.5514 | Yes |
| 44 | ATP5H | NA | ATP5H Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d | 13940 | -0.337 | -0.5465 | Yes |
| 45 | COX7B2 | NA | COX7B2 Entrez, Source | cytochrome c oxidase subunit VIIb2 | 13956 | -0.340 | -0.5420 | Yes |
| 46 | UQCRC1 | NA | UQCRC1 Entrez, Source | ubiquinol-cytochrome c reductase core protein I | 14122 | -0.360 | -0.5454 | Yes |
| 47 | COX17 | NA | COX17 Entrez, Source | COX17 cytochrome c oxidase assembly homolog (S. cerevisiae) | 14255 | -0.374 | -0.5468 | Yes |
| 48 | COX6A1 | NA | COX6A1 Entrez, Source | cytochrome c oxidase subunit VIa polypeptide 1 | 14365 | -0.387 | -0.5468 | Yes |
| 49 | NDUFA8 | NA | NDUFA8 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa | 14368 | -0.388 | -0.5407 | Yes |
| 50 | COX5A | NA | COX5A Entrez, Source | cytochrome c oxidase subunit Va | 14438 | -0.397 | -0.5383 | Yes |
| 51 | COX15 | NA | COX15 Entrez, Source | COX15 homolog, cytochrome c oxidase assembly protein (yeast) | 14547 | -0.413 | -0.5377 | Yes |
| 52 | NDUFS4 | NA | NDUFS4 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 14729 | -0.433 | -0.5409 | Yes |
| 53 | ATP6V1B2 | NA | ATP6V1B2 Entrez, Source | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 | 14796 | -0.445 | -0.5375 | Yes |
| 54 | UQCRQ | NA | UQCRQ Entrez, Source | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | 14817 | -0.449 | -0.5315 | Yes |
| 55 | NDUFV1 | NA | NDUFV1 Entrez, Source | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa | 14914 | -0.463 | -0.5295 | Yes |
| 56 | SDHA | NA | SDHA Entrez, Source | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 14927 | -0.465 | -0.5228 | Yes |
| 57 | ATP4B | NA | ATP4B Entrez, Source | ATPase, H+/K+ exchanging, beta polypeptide | 15041 | -0.482 | -0.5214 | Yes |
| 58 | NDUFS3 | NA | NDUFS3 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) | 15047 | -0.482 | -0.5141 | Yes |
| 59 | ATP6V1G3 | NA | ATP6V1G3 Entrez, Source | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3 | 15088 | -0.487 | -0.5086 | Yes |
| 60 | TCIRG1 | NA | TCIRG1 Entrez, Source | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | 15138 | -0.493 | -0.5035 | Yes |
| 61 | NDUFS2 | NA | NDUFS2 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) | 15173 | -0.499 | -0.4975 | Yes |
| 62 | UQCRFS1 | NA | UQCRFS1 Entrez, Source | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | 15206 | -0.503 | -0.4913 | Yes |
| 63 | COX11 | NA | COX11 Entrez, Source | COX11 homolog, cytochrome c oxidase assembly protein (yeast) | 15210 | -0.504 | -0.4835 | Yes |
| 64 | ATP5O | NA | ATP5O Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) | 15213 | -0.505 | -0.4757 | Yes |
| 65 | NDUFA3 | NA | NDUFA3 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa | 15224 | -0.505 | -0.4682 | Yes |
| 66 | ATP5G3 | NA | ATP5G3 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) | 15229 | -0.506 | -0.4604 | Yes |
| 67 | ATP5G1 | NA | ATP5G1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9) | 15261 | -0.511 | -0.4541 | Yes |
| 68 | COX4I1 | NA | COX4I1 Entrez, Source | cytochrome c oxidase subunit IV isoform 1 | 15269 | -0.512 | -0.4463 | Yes |
| 69 | ATP6AP1 | NA | ATP6AP1 Entrez, Source | ATPase, H+ transporting, lysosomal accessory protein 1 | 15484 | -0.549 | -0.4495 | Yes |
| 70 | ATP5C1 | NA | ATP5C1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 | 15544 | -0.560 | -0.4439 | Yes |
| 71 | NDUFA10 | NA | NDUFA10 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa | 15560 | -0.563 | -0.4358 | Yes |
| 72 | ATP5J | NA | ATP5J Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6 | 15585 | -0.568 | -0.4282 | Yes |
| 73 | NDUFAB1 | NA | NDUFAB1 Entrez, Source | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa | 15592 | -0.569 | -0.4195 | Yes |
| 74 | SDHB | NA | SDHB Entrez, Source | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | 15593 | -0.569 | -0.4105 | Yes |
| 75 | NDUFA7 | NA | NDUFA7 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa | 15694 | -0.588 | -0.4067 | Yes |
| 76 | NDUFB6 | NA | NDUFB6 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | 15771 | -0.603 | -0.4014 | Yes |
| 77 | ATP6V1B1 | NA | ATP6V1B1 Entrez, Source | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 (Renal tubular acidosis with deafness) | 15794 | -0.609 | -0.3930 | Yes |
| 78 | NDUFB8 | NA | NDUFB8 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa | 15852 | -0.621 | -0.3863 | Yes |
| 79 | COX8A | NA | COX8A Entrez, Source | cytochrome c oxidase subunit 8A (ubiquitous) | 15949 | -0.642 | -0.3815 | Yes |
| 80 | COX5B | NA | COX5B Entrez, Source | cytochrome c oxidase subunit Vb | 15956 | -0.644 | -0.3716 | Yes |
| 81 | ATP5L | NA | ATP5L Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit G | 15968 | -0.648 | -0.3620 | Yes |
| 82 | NDUFC2 | NA | NDUFC2 Entrez, Source | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa | 16000 | -0.656 | -0.3533 | Yes |
| 83 | UQCRHL | NA | 16025 | -0.661 | -0.3442 | Yes | ||
| 84 | COX6B1 | NA | COX6B1 Entrez, Source | cytochrome c oxidase subunit Vib polypeptide 1 (ubiquitous) | 16035 | -0.665 | -0.3342 | Yes |
| 85 | NDUFB4 | NA | NDUFB4 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa | 16185 | -0.702 | -0.3313 | Yes |
| 86 | NDUFA1 | NA | NDUFA1 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa | 16223 | -0.711 | -0.3221 | Yes |
| 87 | NDUFA9 | NA | NDUFA9 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa | 16239 | -0.717 | -0.3116 | Yes |
| 88 | ATP5J2 | NA | ATP5J2 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2 | 16267 | -0.725 | -0.3017 | Yes |
| 89 | PPA2 | NA | PPA2 Entrez, Source | pyrophosphatase (inorganic) 2 | 16357 | -0.750 | -0.2947 | Yes |
| 90 | NDUFS1 | NA | NDUFS1 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 16420 | -0.771 | -0.2860 | Yes |
| 91 | UQCR10 | NA | 16475 | -0.787 | -0.2765 | Yes | ||
| 92 | NDUFS5 | NA | NDUFS5 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) | 16478 | -0.790 | -0.2641 | Yes |
| 93 | NDUFA2 | NA | NDUFA2 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa | 16488 | -0.793 | -0.2520 | Yes |
| 94 | COX7A2 | NA | COX7A2 Entrez, Source | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | 16640 | -0.835 | -0.2472 | Yes |
| 95 | NDUFC1 | NA | NDUFC1 Entrez, Source | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa | 16657 | -0.841 | -0.2348 | Yes |
| 96 | NDUFA4 | NA | NDUFA4 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa | 16700 | -0.853 | -0.2236 | Yes |
| 97 | UQCRH | NA | UQCRH Entrez, Source | ubiquinol-cytochrome c reductase hinge protein | 16759 | -0.873 | -0.2130 | Yes |
| 98 | SDHD | NA | SDHD Entrez, Source | succinate dehydrogenase complex, subunit D, integral membrane protein | 16792 | -0.886 | -0.2008 | Yes |
| 99 | COX6C | NA | COX6C Entrez, Source | cytochrome c oxidase subunit VIc | 16973 | -0.957 | -0.1956 | Yes |
| 100 | ATP6V1G2 | NA | ATP6V1G2 Entrez, Source | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 | 16993 | -0.965 | -0.1814 | Yes |
| 101 | ATP5A1 | NA | ATP5A1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle | 17098 | -1.012 | -0.1711 | Yes |
| 102 | NDUFB5 | NA | NDUFB5 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | 17105 | -1.017 | -0.1554 | Yes |
| 103 | ATP5B | NA | ATP5B Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide | 17107 | -1.018 | -0.1393 | Yes |
| 104 | ATP5F1 | NA | ATP5F1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1 | 17165 | -1.039 | -0.1260 | Yes |
| 105 | COX7B | NA | COX7B Entrez, Source | cytochrome c oxidase subunit VIIb | 17181 | -1.049 | -0.1103 | Yes |
| 106 | NDUFB3 | NA | NDUFB3 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa | 17222 | -1.073 | -0.0955 | Yes |
| 107 | NDUFB1 | NA | NDUFB1 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa | 17262 | -1.097 | -0.0803 | Yes |
| 108 | UQCRB | NA | UQCRB Entrez, Source | ubiquinol-cytochrome c reductase binding protein | 17309 | -1.123 | -0.0651 | Yes |
| 109 | COX7C | NA | COX7C Entrez, Source | cytochrome c oxidase subunit VIIc | 17459 | -1.227 | -0.0539 | Yes |
| 110 | UQCRC2 | NA | UQCRC2 Entrez, Source | ubiquinol-cytochrome c reductase core protein II | 17465 | -1.232 | -0.0347 | Yes |
| 111 | LHPP | NA | LHPP Entrez, Source | - | 17608 | -1.360 | -0.0211 | Yes |
| 112 | NDUFA5 | NA | NDUFA5 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa | 17656 | -1.422 | -0.0012 | Yes |
| 113 | NDUFA4L2 | NA | NDUFA4L2 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 17899 | -1.860 | 0.0148 | Yes |
