Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w1a_vs_wt_vs_wt.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp_repos |
| Phenotype | w1a_vs_wt.cls#ago1w1a_versus_ago1gfp_repos |
| Upregulated in class | ago1w1a |
| GeneSet | KEGG_GLYCOSAMINOGLYCAN_DEGRADATION |
| Enrichment Score (ES) | 0.51881117 |
| Normalized Enrichment Score (NES) | 1.3928403 |
| Nominal p-value | 0.08389262 |
| FDR q-value | 0.28793177 |
| FWER p-Value | 0.996 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | HYAL4 | NA | HYAL4 Entrez, Source | hyaluronoglucosaminidase 4 | 552 | 1.479 | 0.1246 | Yes |
| 2 | SGSH | NA | SGSH Entrez, Source | N-sulfoglucosamine sulfohydrolase (sulfamidase) | 675 | 1.342 | 0.2584 | Yes |
| 3 | IDS | NA | IDS Entrez, Source | iduronate 2-sulfatase (Hunter syndrome) | 991 | 1.126 | 0.3591 | Yes |
| 4 | HGSNAT | NA | HGSNAT Entrez, Source | heparan-alpha-glucosaminide N-acetyltransferase | 2758 | 0.638 | 0.3286 | Yes |
| 5 | GNS | NA | GNS Entrez, Source | glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID) | 3135 | 0.577 | 0.3684 | Yes |
| 6 | IDUA | NA | IDUA Entrez, Source | iduronidase, alpha-L- | 3255 | 0.558 | 0.4203 | Yes |
| 7 | HPSE2 | NA | HPSE2 Entrez, Source | heparanase 2 | 3330 | 0.546 | 0.4734 | Yes |
| 8 | HYAL3 | NA | HYAL3 Entrez, Source | hyaluronoglucosaminidase 3 | 3582 | 0.513 | 0.5133 | Yes |
| 9 | HYAL2 | NA | HYAL2 Entrez, Source | hyaluronoglucosaminidase 2 | 4288 | 0.423 | 0.5188 | Yes |
| 10 | GUSB | NA | GUSB Entrez, Source | glucuronidase, beta | 5597 | 0.296 | 0.4777 | No |
| 11 | HS3ST3A1 | NA | HS3ST3A1 Entrez, Source | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 6780 | 0.197 | 0.4333 | No |
| 12 | SPAM1 | NA | SPAM1 Entrez, Source | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) | 8541 | 0.069 | 0.3435 | No |
| 13 | HEXB | NA | HEXB Entrez, Source | hexosaminidase B (beta polypeptide) | 9141 | 0.025 | 0.3131 | No |
| 14 | HS3ST3B1 | NA | HS3ST3B1 Entrez, Source | heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 | 9556 | 0.000 | 0.2903 | No |
| 15 | ARSB | NA | ARSB Entrez, Source | arylsulfatase B | 12167 | -0.170 | 0.1643 | No |
| 16 | HEXA | NA | HEXA Entrez, Source | hexosaminidase A (alpha polypeptide) | 12704 | -0.219 | 0.1577 | No |
| 17 | GALNS | NA | GALNS Entrez, Source | galactosamine (N-acetyl)-6-sulfate sulfatase (Morquio syndrome, mucopolysaccharidosis type IVA) | 13058 | -0.249 | 0.1644 | No |
| 18 | NAGLU | NA | NAGLU Entrez, Source | N-acetylglucosaminidase, alpha- (Sanfilippo disease IIIB) | 13379 | -0.279 | 0.1760 | No |
| 19 | GLB1 | NA | GLB1 Entrez, Source | galactosidase, beta 1 | 13540 | -0.295 | 0.1981 | No |
| 20 | HPSE | NA | HPSE Entrez, Source | heparanase | 15449 | -0.542 | 0.1498 | No |
