Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w1a_vs_wt_vs_wt.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp_repos |
| Phenotype | w1a_vs_wt.cls#ago1w1a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | KEGG_BETA_ALANINE_METABOLISM |
| Enrichment Score (ES) | -0.54790413 |
| Normalized Enrichment Score (NES) | -1.5733705 |
| Nominal p-value | 0.025114154 |
| FDR q-value | 0.06262838 |
| FWER p-Value | 0.617 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SRM | NA | SRM Entrez, Source | spermidine synthase | 904 | 1.174 | 0.0441 | No |
| 2 | MLYCD | NA | MLYCD Entrez, Source | malonyl-CoA decarboxylase | 5093 | 0.342 | -0.1593 | No |
| 3 | SMS | NA | SMS Entrez, Source | spermine synthase | 6295 | 0.237 | -0.2065 | No |
| 4 | UPB1 | NA | UPB1 Entrez, Source | ureidopropionase, beta | 7506 | 0.144 | -0.2617 | No |
| 5 | GAD1 | NA | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 9933 | -0.015 | -0.3941 | No |
| 6 | DPYS | NA | DPYS Entrez, Source | dihydropyrimidinase | 10307 | -0.039 | -0.4116 | No |
| 7 | CNDP1 | NA | CNDP1 Entrez, Source | carnosine dipeptidase 1 (metallopeptidase M20 family) | 10482 | -0.047 | -0.4175 | No |
| 8 | ALDH1B1 | NA | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 11847 | -0.144 | -0.4811 | No |
| 9 | HIBCH | NA | HIBCH Entrez, Source | 3-hydroxyisobutyryl-Coenzyme A hydrolase | 12823 | -0.228 | -0.5166 | Yes |
| 10 | ALDH7A1 | NA | ALDH7A1 Entrez, Source | aldehyde dehydrogenase 7 family, member A1 | 13180 | -0.261 | -0.5154 | Yes |
| 11 | ECHS1 | NA | ECHS1 Entrez, Source | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 13439 | -0.286 | -0.5067 | Yes |
| 12 | ALDH9A1 | NA | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 13994 | -0.345 | -0.5096 | Yes |
| 13 | ALDH3A2 | NA | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 14517 | -0.407 | -0.5058 | Yes |
| 14 | GAD2 | NA | GAD2 Entrez, Source | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) | 14709 | -0.430 | -0.4819 | Yes |
| 15 | DPYD | NA | DPYD Entrez, Source | dihydropyrimidine dehydrogenase | 15908 | -0.634 | -0.4972 | Yes |
| 16 | EHHADH | NA | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 16508 | -0.801 | -0.4661 | Yes |
| 17 | ALDH2 | NA | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 16658 | -0.842 | -0.4069 | Yes |
| 18 | HADHA | NA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 16783 | -0.880 | -0.3433 | Yes |
| 19 | ACADM | NA | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 17198 | -1.057 | -0.2815 | Yes |
| 20 | AOC2 | NA | AOC2 Entrez, Source | amine oxidase, copper containing 2 (retina-specific) | 17273 | -1.102 | -0.1973 | Yes |
| 21 | ABAT | NA | ABAT Entrez, Source | 4-aminobutyrate aminotransferase | 17441 | -1.211 | -0.1096 | Yes |
| 22 | AOC3 | NA | AOC3 Entrez, Source | amine oxidase, copper containing 3 (vascular adhesion protein 1) | 17906 | -1.868 | 0.0144 | Yes |
