Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w1a_vs_wt_vs_wt.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp_repos |
| Phenotype | w1a_vs_wt.cls#ago1w1a_versus_ago1gfp_repos |
| Upregulated in class | ago1w1a |
| GeneSet | HALLMARK_MYC_TARGETS_V2 |
| Enrichment Score (ES) | 0.44358757 |
| Normalized Enrichment Score (NES) | 1.4849004 |
| Nominal p-value | 0.023728814 |
| FDR q-value | 0.024887977 |
| FWER p-Value | 0.276 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SLC19A1 | NA | SLC19A1 Entrez, Source | solute carrier family 19 (folate transporter), member 1 | 879 | 1.188 | -0.0044 | Yes |
| 2 | SRM | NA | SRM Entrez, Source | spermidine synthase | 904 | 1.174 | 0.0379 | Yes |
| 3 | GRWD1 | NA | GRWD1 Entrez, Source | glutamate-rich WD repeat containing 1 | 1283 | 0.989 | 0.0538 | Yes |
| 4 | NOC4L | NA | NOC4L Entrez, Source | nucleolar complex associated 4 homolog (S. cerevisiae) | 1331 | 0.971 | 0.0873 | Yes |
| 5 | RRP12 | NA | 1455 | 0.926 | 0.1149 | Yes | ||
| 6 | TCOF1 | NA | TCOF1 Entrez, Source | Treacher Collins-Franceschetti syndrome 1 | 1545 | 0.897 | 0.1434 | Yes |
| 7 | RRP9 | NA | 1735 | 0.842 | 0.1642 | Yes | ||
| 8 | PPAN | NA | PPAN Entrez, Source | peter pan homolog (Drosophila) | 1867 | 0.816 | 0.1873 | Yes |
| 9 | PPRC1 | NA | PPRC1 Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator-related 1 | 1950 | 0.798 | 0.2124 | Yes |
| 10 | MYBBP1A | NA | MYBBP1A Entrez, Source | MYB binding protein (P160) 1a | 1971 | 0.793 | 0.2408 | Yes |
| 11 | NOP2 | NA | 2078 | 0.771 | 0.2636 | Yes | ||
| 12 | BYSL | NA | BYSL Entrez, Source | bystin-like | 2086 | 0.769 | 0.2918 | Yes |
| 13 | PES1 | NA | PES1 Entrez, Source | pescadillo homolog 1, containing BRCT domain (zebrafish) | 2192 | 0.746 | 0.3137 | Yes |
| 14 | NIP7 | NA | NIP7 Entrez, Source | nuclear import 7 homolog (S. cerevisiae) | 2197 | 0.745 | 0.3412 | Yes |
| 15 | IMP4 | NA | IMP4 Entrez, Source | IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) | 2255 | 0.734 | 0.3653 | Yes |
| 16 | FARSA | NA | 2403 | 0.703 | 0.3833 | Yes | ||
| 17 | NOP16 | NA | 3175 | 0.570 | 0.3619 | Yes | ||
| 18 | PUS1 | NA | PUS1 Entrez, Source | pseudouridylate synthase 1 | 3277 | 0.556 | 0.3770 | Yes |
| 19 | UTP20 | NA | UTP20 Entrez, Source | UTP20, small subunit (SSU) processome component, homolog (yeast) | 3296 | 0.551 | 0.3965 | Yes |
| 20 | RABEPK | NA | RABEPK Entrez, Source | Rab9 effector protein with kelch motifs | 3521 | 0.520 | 0.4035 | Yes |
| 21 | WDR43 | NA | WDR43 Entrez, Source | WD repeat domain 43 | 3884 | 0.477 | 0.4012 | Yes |
| 22 | NOP56 | NA | 4024 | 0.459 | 0.4106 | Yes | ||
| 23 | MRTO4 | NA | 4176 | 0.438 | 0.4185 | Yes | ||
| 24 | NOLC1 | NA | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 4488 | 0.402 | 0.4163 | Yes |
| 25 | IPO4 | NA | IPO4 Entrez, Source | importin 4 | 4719 | 0.381 | 0.4177 | Yes |
| 26 | WDR74 | NA | WDR74 Entrez, Source | WD repeat domain 74 | 4851 | 0.367 | 0.4241 | Yes |
| 27 | TBRG4 | NA | TBRG4 Entrez, Source | transforming growth factor beta regulator 4 | 4866 | 0.365 | 0.4369 | Yes |
| 28 | MAP3K6 | NA | MAP3K6 Entrez, Source | mitogen-activated protein kinase kinase kinase 6 | 4984 | 0.353 | 0.4436 | Yes |
| 29 | PA2G4 | NA | PA2G4 Entrez, Source | proliferation-associated 2G4, 38kDa | 5573 | 0.298 | 0.4222 | No |
| 30 | CDK4 | NA | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 5679 | 0.288 | 0.4271 | No |
| 31 | HK2 | NA | HK2 Entrez, Source | hexokinase 2 | 5760 | 0.282 | 0.4332 | No |
| 32 | PRMT3 | NA | PRMT3 Entrez, Source | protein arginine methyltransferase 3 | 6380 | 0.230 | 0.4075 | No |
| 33 | AIMP2 | NA | 6449 | 0.225 | 0.4121 | No | ||
| 34 | MCM5 | NA | MCM5 Entrez, Source | MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) | 6527 | 0.218 | 0.4160 | No |
| 35 | MPHOSPH10 | NA | MPHOSPH10 Entrez, Source | M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) | 6624 | 0.210 | 0.4185 | No |
| 36 | DCTPP1 | NA | 6851 | 0.191 | 0.4131 | No | ||
| 37 | LAS1L | NA | LAS1L Entrez, Source | LAS1-like (S. cerevisiae) | 6899 | 0.188 | 0.4175 | No |
| 38 | RCL1 | NA | RCL1 Entrez, Source | RNA terminal phosphate cyclase-like 1 | 7151 | 0.169 | 0.4100 | No |
| 39 | SLC29A2 | NA | SLC29A2 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 2 | 7442 | 0.148 | 0.3994 | No |
| 40 | HSPD1 | NA | HSPD1 Entrez, Source | heat shock 60kDa protein 1 (chaperonin) | 7500 | 0.145 | 0.4016 | No |
| 41 | EXOSC5 | NA | EXOSC5 Entrez, Source | exosome component 5 | 7951 | 0.111 | 0.3809 | No |
| 42 | MCM4 | NA | MCM4 Entrez, Source | MCM4 minichromosome maintenance deficient 4 (S. cerevisiae) | 8704 | 0.057 | 0.3415 | No |
| 43 | PLK4 | NA | PLK4 Entrez, Source | polo-like kinase 4 (Drosophila) | 8914 | 0.043 | 0.3316 | No |
| 44 | PHB | NA | PHB Entrez, Source | prohibitin | 9094 | 0.028 | 0.3227 | No |
| 45 | TMEM97 | NA | TMEM97 Entrez, Source | transmembrane protein 97 | 9452 | 0.004 | 0.3032 | No |
| 46 | SUPV3L1 | NA | SUPV3L1 Entrez, Source | suppressor of var1, 3-like 1 (S. cerevisiae) | 10052 | -0.022 | 0.2709 | No |
| 47 | DDX18 | NA | DDX18 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 10219 | -0.032 | 0.2630 | No |
| 48 | SORD | NA | SORD Entrez, Source | sorbitol dehydrogenase | 11068 | -0.082 | 0.2192 | No |
| 49 | HSPE1 | NA | HSPE1 Entrez, Source | heat shock 10kDa protein 1 (chaperonin 10) | 12070 | -0.161 | 0.1699 | No |
| 50 | PLK1 | NA | PLK1 Entrez, Source | polo-like kinase 1 (Drosophila) | 12400 | -0.191 | 0.1588 | No |
| 51 | GNL3 | NA | GNL3 Entrez, Source | guanine nucleotide binding protein-like 3 (nucleolar) | 12579 | -0.208 | 0.1567 | No |
| 52 | NDUFAF4 | NA | 12793 | -0.227 | 0.1534 | No | ||
| 53 | NPM1 | NA | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 12872 | -0.232 | 0.1577 | No |
| 54 | CBX3 | NA | CBX3 Entrez, Source | chromobox homolog 3 (HP1 gamma homolog, Drosophila) | 13698 | -0.311 | 0.1237 | No |
| 55 | MYC | NA | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 13741 | -0.315 | 0.1331 | No |
| 56 | TFB2M | NA | TFB2M Entrez, Source | transcription factor B2, mitochondrial | 16400 | -0.765 | 0.0148 | No |
| 57 | UNG | NA | UNG Entrez, Source | uracil-DNA glycosylase | 16725 | -0.865 | 0.0290 | No |
| 58 | DUSP2 | NA | DUSP2 Entrez, Source | dual specificity phosphatase 2 | 17607 | -1.360 | 0.0309 | No |
