Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w1a_vs_wt_vs_wt.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp_repos |
| Phenotype | w1a_vs_wt.cls#ago1w1a_versus_ago1gfp_repos |
| Upregulated in class | ago1w1a |
| GeneSet | HALLMARK_HEDGEHOG_SIGNALING |
| Enrichment Score (ES) | 0.3982051 |
| Normalized Enrichment Score (NES) | 1.1821291 |
| Nominal p-value | 0.22508591 |
| FDR q-value | 0.255745 |
| FWER p-Value | 0.993 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CNTFR | NA | CNTFR Entrez, Source | ciliary neurotrophic factor receptor | 163 | 2.605 | 0.1175 | Yes |
| 2 | PML | NA | PML Entrez, Source | promyelocytic leukemia | 307 | 1.956 | 0.2046 | Yes |
| 3 | ETS2 | NA | ETS2 Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) | 508 | 1.534 | 0.2681 | Yes |
| 4 | TLE1 | NA | TLE1 Entrez, Source | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | 727 | 1.305 | 0.3194 | Yes |
| 5 | NRP2 | NA | NRP2 Entrez, Source | neuropilin 2 | 1180 | 1.030 | 0.3445 | Yes |
| 6 | NRP1 | NA | NRP1 Entrez, Source | neuropilin 1 | 1787 | 0.832 | 0.3515 | Yes |
| 7 | NRCAM | NA | NRCAM Entrez, Source | neuronal cell adhesion molecule | 2195 | 0.745 | 0.3653 | Yes |
| 8 | MYH9 | NA | MYH9 Entrez, Source | myosin, heavy chain 9, non-muscle | 2467 | 0.691 | 0.3839 | Yes |
| 9 | GLI1 | NA | GLI1 Entrez, Source | glioma-associated oncogene homolog 1 (zinc finger protein) | 2769 | 0.636 | 0.3982 | Yes |
| 10 | L1CAM | NA | L1CAM Entrez, Source | L1 cell adhesion molecule | 3408 | 0.535 | 0.3890 | No |
| 11 | CRMP1 | NA | CRMP1 Entrez, Source | collapsin response mediator protein 1 | 4291 | 0.423 | 0.3609 | No |
| 12 | OPHN1 | NA | OPHN1 Entrez, Source | oligophrenin 1 | 4379 | 0.414 | 0.3762 | No |
| 13 | PTCH1 | NA | PTCH1 Entrez, Source | patched homolog 1 (Drosophila) | 4725 | 0.380 | 0.3756 | No |
| 14 | UNC5C | NA | UNC5C Entrez, Source | unc-5 homolog C (C. elegans) | 5354 | 0.317 | 0.3564 | No |
| 15 | HEY2 | NA | HEY2 Entrez, Source | hairy/enhancer-of-split related with YRPW motif 2 | 5974 | 0.265 | 0.3351 | No |
| 16 | CDK5R1 | NA | CDK5R1 Entrez, Source | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 7014 | 0.179 | 0.2865 | No |
| 17 | CDK6 | NA | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 7145 | 0.170 | 0.2876 | No |
| 18 | ACHE | NA | ACHE Entrez, Source | acetylcholinesterase (Yt blood group) | 7305 | 0.159 | 0.2866 | No |
| 19 | VEGFA | NA | 7903 | 0.115 | 0.2592 | No | ||
| 20 | RASA1 | NA | RASA1 Entrez, Source | RAS p21 protein activator (GTPase activating protein) 1 | 7915 | 0.114 | 0.2641 | No |
| 21 | TLE3 | NA | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 8467 | 0.074 | 0.2374 | No |
| 22 | NF1 | NA | NF1 Entrez, Source | neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) | 8924 | 0.042 | 0.2142 | No |
| 23 | NKX6-1 | NA | NKX6-1 Entrez, Source | NK6 transcription factor related, locus 1 (Drosophila) | 9605 | 0.000 | 0.1767 | No |
| 24 | LDB1 | NA | LDB1 Entrez, Source | LIM domain binding 1 | 10021 | -0.020 | 0.1548 | No |
| 25 | DPYSL2 | NA | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 10090 | -0.025 | 0.1523 | No |
| 26 | SHH | NA | SHH Entrez, Source | sonic hedgehog homolog (Drosophila) | 10664 | -0.059 | 0.1235 | No |
| 27 | AMOT | NA | AMOT Entrez, Source | angiomotin | 12786 | -0.226 | 0.0175 | No |
| 28 | RTN1 | NA | RTN1 Entrez, Source | reticulon 1 | 13490 | -0.291 | -0.0071 | No |
| 29 | SLIT1 | NA | SLIT1 Entrez, Source | slit homolog 1 (Drosophila) | 13720 | -0.313 | -0.0046 | No |
| 30 | SCG2 | NA | SCG2 Entrez, Source | secretogranin II (chromogranin C) | 14036 | -0.349 | -0.0050 | No |
| 31 | CELSR1 | NA | CELSR1 Entrez, Source | cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila) | 15331 | -0.521 | -0.0510 | No |
| 32 | THY1 | NA | THY1 Entrez, Source | Thy-1 cell surface antigen | 15540 | -0.559 | -0.0354 | No |
| 33 | PLG | NA | PLG Entrez, Source | plasminogen | 16761 | -0.873 | -0.0602 | No |
| 34 | VLDLR | NA | VLDLR Entrez, Source | very low density lipoprotein receptor | 17333 | -1.141 | -0.0363 | No |
| 35 | HEY1 | NA | HEY1 Entrez, Source | hairy/enhancer-of-split related with YRPW motif 1 | 17832 | -1.694 | 0.0185 | No |
