Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w1a_vs_wt_vs_wt.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp_repos |
| Phenotype | w1a_vs_wt.cls#ago1w1a_versus_ago1gfp_repos |
| Upregulated in class | ago1w1a |
| GeneSet | HALLMARK_APICAL_SURFACE |
| Enrichment Score (ES) | 0.44433442 |
| Normalized Enrichment Score (NES) | 1.393614 |
| Nominal p-value | 0.05227656 |
| FDR q-value | 0.048644118 |
| FWER p-Value | 0.545 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | IL2RG | NA | IL2RG Entrez, Source | interleukin 2 receptor, gamma (severe combined immunodeficiency) | 57 | 3.955 | 0.1516 | Yes |
| 2 | PLAUR | NA | PLAUR Entrez, Source | plasminogen activator, urokinase receptor | 140 | 2.784 | 0.2560 | Yes |
| 3 | LYPD3 | NA | LYPD3 Entrez, Source | LY6/PLAUR domain containing 3 | 224 | 2.291 | 0.3411 | Yes |
| 4 | AFAP1L2 | NA | 759 | 1.277 | 0.3616 | Yes | ||
| 5 | EPHB4 | NA | EPHB4 Entrez, Source | EPH receptor B4 | 1726 | 0.845 | 0.3413 | Yes |
| 6 | RTN4RL1 | NA | RTN4RL1 Entrez, Source | reticulon 4 receptor-like 1 | 1882 | 0.813 | 0.3646 | Yes |
| 7 | GHRL | NA | GHRL Entrez, Source | ghrelin/obestatin preprohormone | 2071 | 0.771 | 0.3844 | Yes |
| 8 | CX3CL1 | NA | CX3CL1 Entrez, Source | chemokine (C-X3-C motif) ligand 1 | 2526 | 0.681 | 0.3860 | Yes |
| 9 | DCBLD2 | NA | DCBLD2 Entrez, Source | discoidin, CUB and LCCL domain containing 2 | 2529 | 0.679 | 0.4125 | Yes |
| 10 | HSPB1 | NA | HSPB1 Entrez, Source | heat shock 27kDa protein 1 | 2793 | 0.631 | 0.4227 | Yes |
| 11 | GATA3 | NA | GATA3 Entrez, Source | GATA binding protein 3 | 2844 | 0.624 | 0.4443 | Yes |
| 12 | LYN | NA | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 4244 | 0.428 | 0.3839 | No |
| 13 | SLC22A12 | NA | SLC22A12 Entrez, Source | solute carrier family 22 (organic anion/cation transporter), member 12 | 4287 | 0.423 | 0.3982 | No |
| 14 | SULF2 | NA | SULF2 Entrez, Source | sulfatase 2 | 5349 | 0.318 | 0.3520 | No |
| 15 | AKAP7 | NA | AKAP7 Entrez, Source | A kinase (PRKA) anchor protein 7 | 5496 | 0.303 | 0.3559 | No |
| 16 | CROCC | NA | CROCC Entrez, Source | ciliary rootlet coiled-coil, rootletin | 5564 | 0.299 | 0.3638 | No |
| 17 | APP | NA | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 5577 | 0.297 | 0.3748 | No |
| 18 | NCOA6 | NA | NCOA6 Entrez, Source | nuclear receptor coactivator 6 | 5655 | 0.291 | 0.3820 | No |
| 19 | NTNG1 | NA | NTNG1 Entrez, Source | netrin G1 | 6004 | 0.263 | 0.3730 | No |
| 20 | ADAM10 | NA | ADAM10 Entrez, Source | ADAM metallopeptidase domain 10 | 6234 | 0.242 | 0.3699 | No |
| 21 | BRCA1 | NA | BRCA1 Entrez, Source | breast cancer 1, early onset | 6475 | 0.223 | 0.3654 | No |
| 22 | ATP6V0A4 | NA | ATP6V0A4 Entrez, Source | ATPase, H+ transporting, lysosomal V0 subunit a4 | 8309 | 0.085 | 0.2676 | No |
| 23 | RHCG | NA | RHCG Entrez, Source | Rh family, C glycoprotein | 8824 | 0.049 | 0.2411 | No |
| 24 | ATP8B1 | NA | ATP8B1 Entrez, Source | ATPase, Class I, type 8B, member 1 | 10227 | -0.033 | 0.1651 | No |
| 25 | EFNA5 | NA | EFNA5 Entrez, Source | ephrin-A5 | 10682 | -0.060 | 0.1424 | No |
| 26 | MAL | NA | MAL Entrez, Source | mal, T-cell differentiation protein | 11007 | -0.078 | 0.1276 | No |
| 27 | FLOT2 | NA | FLOT2 Entrez, Source | flotillin 2 | 11221 | -0.092 | 0.1194 | No |
| 28 | MDGA1 | NA | MDGA1 Entrez, Source | MAM domain containing glycosylphosphatidylinositol anchor 1 | 11410 | -0.106 | 0.1132 | No |
| 29 | B4GALT1 | NA | B4GALT1 Entrez, Source | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 11658 | -0.128 | 0.1046 | No |
| 30 | SCUBE1 | NA | SCUBE1 Entrez, Source | signal peptide, CUB domain, EGF-like 1 | 11748 | -0.135 | 0.1050 | No |
| 31 | PCSK9 | NA | PCSK9 Entrez, Source | proprotein convertase subtilisin/kexin type 9 | 12045 | -0.159 | 0.0949 | No |
| 32 | ADIPOR2 | NA | ADIPOR2 Entrez, Source | adiponectin receptor 2 | 12436 | -0.196 | 0.0810 | No |
| 33 | IL2RB | NA | IL2RB Entrez, Source | interleukin 2 receptor, beta | 12478 | -0.199 | 0.0865 | No |
| 34 | TMEM8B | NA | 13079 | -0.251 | 0.0632 | No | ||
| 35 | SLC34A3 | NA | SLC34A3 Entrez, Source | solute carrier family 34 (sodium phosphate), member 3 | 13194 | -0.262 | 0.0672 | No |
| 36 | SHROOM2 | NA | SHROOM2 Entrez, Source | shroom family member 2 | 13451 | -0.288 | 0.0644 | No |
| 37 | SRPX | NA | SRPX Entrez, Source | sushi-repeat-containing protein, X-linked | 13926 | -0.333 | 0.0512 | No |
| 38 | GAS1 | NA | GAS1 Entrez, Source | growth arrest-specific 1 | 14596 | -0.418 | 0.0307 | No |
| 39 | GSTM3 | NA | GSTM3 Entrez, Source | glutathione S-transferase M3 (brain) | 15376 | -0.529 | 0.0084 | No |
| 40 | PKHD1 | NA | PKHD1 Entrez, Source | polycystic kidney and hepatic disease 1 (autosomal recessive) | 15429 | -0.538 | 0.0266 | No |
| 41 | CD160 | NA | CD160 Entrez, Source | CD160 molecule | 15497 | -0.551 | 0.0445 | No |
| 42 | THY1 | NA | THY1 Entrez, Source | Thy-1 cell surface antigen | 15540 | -0.559 | 0.0640 | No |
| 43 | SLC2A4 | NA | SLC2A4 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 4 | 17962 | -2.066 | 0.0113 | No |
