Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w1a_vs_wt_vs_wt.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp_repos |
| Phenotype | w1a_vs_wt.cls#ago1w1a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | HALLMARK_ANGIOGENESIS |
| Enrichment Score (ES) | -0.34894213 |
| Normalized Enrichment Score (NES) | -1.1130238 |
| Nominal p-value | 0.2994924 |
| FDR q-value | 0.28029794 |
| FWER p-Value | 0.993 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | OLR1 | NA | OLR1 Entrez, Source | oxidised low density lipoprotein (lectin-like) receptor 1 | 130 | 2.873 | 0.0855 | No |
| 2 | TNFRSF21 | NA | TNFRSF21 Entrez, Source | tumor necrosis factor receptor superfamily, member 21 | 233 | 2.250 | 0.1524 | No |
| 3 | THBD | NA | THBD Entrez, Source | thrombomodulin | 429 | 1.656 | 0.1951 | No |
| 4 | JAG1 | NA | JAG1 Entrez, Source | jagged 1 (Alagille syndrome) | 516 | 1.523 | 0.2395 | No |
| 5 | PDGFA | NA | PDGFA Entrez, Source | platelet-derived growth factor alpha polypeptide | 1146 | 1.048 | 0.2386 | No |
| 6 | NRP1 | NA | NRP1 Entrez, Source | neuropilin 1 | 1787 | 0.832 | 0.2302 | No |
| 7 | FGFR1 | NA | FGFR1 Entrez, Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 1820 | 0.825 | 0.2550 | No |
| 8 | FSTL1 | NA | FSTL1 Entrez, Source | follistatin-like 1 | 2155 | 0.753 | 0.2609 | No |
| 9 | JAG2 | NA | JAG2 Entrez, Source | jagged 2 | 2293 | 0.726 | 0.2767 | No |
| 10 | VAV2 | NA | VAV2 Entrez, Source | vav 2 oncogene | 2382 | 0.706 | 0.2946 | No |
| 11 | MSX1 | NA | MSX1 Entrez, Source | msh homeobox homolog 1 (Drosophila) | 3351 | 0.543 | 0.2588 | No |
| 12 | SLCO2A1 | NA | SLCO2A1 Entrez, Source | solute carrier organic anion transporter family, member 2A1 | 3549 | 0.516 | 0.2645 | No |
| 13 | TIMP1 | NA | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 3797 | 0.486 | 0.2666 | No |
| 14 | APP | NA | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 5577 | 0.297 | 0.1781 | No |
| 15 | VEGFA | NA | 7903 | 0.115 | 0.0535 | No | ||
| 16 | PF4 | NA | PF4 Entrez, Source | platelet factor 4 (chemokine (C-X-C motif) ligand 4) | 8263 | 0.089 | 0.0366 | No |
| 17 | PRG2 | NA | PRG2 Entrez, Source | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 8301 | 0.085 | 0.0373 | No |
| 18 | VCAN | NA | 8980 | 0.036 | 0.0011 | No | ||
| 19 | CXCL6 | NA | CXCL6 Entrez, Source | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 9563 | 0.000 | -0.0310 | No |
| 20 | APOH | NA | APOH Entrez, Source | apolipoprotein H (beta-2-glycoprotein I) | 9992 | -0.018 | -0.0540 | No |
| 21 | CCND2 | NA | CCND2 Entrez, Source | cyclin D2 | 10056 | -0.023 | -0.0568 | No |
| 22 | KCNJ8 | NA | KCNJ8 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 8 | 10305 | -0.039 | -0.0692 | No |
| 23 | POSTN | NA | POSTN Entrez, Source | periostin, osteoblast specific factor | 10809 | -0.065 | -0.0948 | No |
| 24 | PTK2 | NA | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 11849 | -0.144 | -0.1475 | No |
| 25 | LRPAP1 | NA | LRPAP1 Entrez, Source | low density lipoprotein receptor-related protein associated protein 1 | 12807 | -0.227 | -0.1930 | No |
| 26 | ITGAV | NA | ITGAV Entrez, Source | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 14332 | -0.383 | -0.2646 | No |
| 27 | STC1 | NA | STC1 Entrez, Source | stanniocalcin 1 | 14600 | -0.419 | -0.2659 | No |
| 28 | SPP1 | NA | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 15059 | -0.484 | -0.2755 | No |
| 29 | SERPINA5 | NA | SERPINA5 Entrez, Source | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 15468 | -0.545 | -0.2804 | No |
| 30 | S100A4 | NA | S100A4 Entrez, Source | S100 calcium binding protein A4 | 15715 | -0.591 | -0.2749 | No |
| 31 | PGLYRP1 | NA | PGLYRP1 Entrez, Source | peptidoglycan recognition protein 1 | 16694 | -0.851 | -0.3014 | No |
| 32 | COL5A2 | NA | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 17557 | -1.302 | -0.3069 | Yes |
| 33 | COL3A1 | NA | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 17611 | -1.363 | -0.2659 | Yes |
| 34 | LUM | NA | LUM Entrez, Source | lumican | 17955 | -2.047 | -0.2188 | Yes |
| 35 | VTN | NA | VTN Entrez, Source | vitronectin | 18023 | -2.397 | -0.1452 | Yes |
| 36 | LPL | NA | LPL Entrez, Source | lipoprotein lipase | 18162 | -4.745 | 0.0003 | Yes |
