Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | w1a_vs_wt_vs_wt.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp.w1a_vs_wt.cls #ago1w1a_versus_ago1gfp_repos |
| Phenotype | w1a_vs_wt.cls#ago1w1a_versus_ago1gfp_repos |
| Upregulated in class | ago1gfp |
| GeneSet | HALLMARK_ANDROGEN_RESPONSE |
| Enrichment Score (ES) | -0.33833134 |
| Normalized Enrichment Score (NES) | -1.2970065 |
| Nominal p-value | 0.05154639 |
| FDR q-value | 0.11307803 |
| FWER p-Value | 0.619 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | KRT8 | NA | KRT8 Entrez, Source | keratin 8 | 412 | 1.689 | 0.0080 | No |
| 2 | ABHD2 | NA | ABHD2 Entrez, Source | abhydrolase domain containing 2 | 1005 | 1.117 | -0.0044 | No |
| 3 | ADRM1 | NA | ADRM1 Entrez, Source | adhesion regulating molecule 1 | 1041 | 1.098 | 0.0137 | No |
| 4 | KRT19 | NA | KRT19 Entrez, Source | keratin 19 | 1209 | 1.015 | 0.0230 | No |
| 5 | HMGCS1 | NA | HMGCS1 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) | 1289 | 0.985 | 0.0366 | No |
| 6 | CCND3 | NA | CCND3 Entrez, Source | cyclin D3 | 1347 | 0.964 | 0.0511 | No |
| 7 | RRP12 | NA | 1455 | 0.926 | 0.0621 | No | ||
| 8 | PDLIM5 | NA | PDLIM5 Entrez, Source | PDZ and LIM domain 5 | 1485 | 0.914 | 0.0771 | No |
| 9 | ACTN1 | NA | ACTN1 Entrez, Source | actinin, alpha 1 | 1755 | 0.838 | 0.0775 | No |
| 10 | B2M | NA | B2M Entrez, Source | beta-2-microglobulin | 1917 | 0.805 | 0.0833 | No |
| 11 | H1F0 | NA | H1F0 Entrez, Source | H1 histone family, member 0 | 1944 | 0.799 | 0.0964 | No |
| 12 | INPP4B | NA | INPP4B Entrez, Source | inositol polyphosphate-4-phosphatase, type II, 105kDa | 1989 | 0.790 | 0.1084 | No |
| 13 | TMPRSS2 | NA | TMPRSS2 Entrez, Source | transmembrane protease, serine 2 | 2180 | 0.748 | 0.1116 | No |
| 14 | ZMIZ1 | NA | 2242 | 0.736 | 0.1216 | No | ||
| 15 | MAK | NA | MAK Entrez, Source | male germ cell-associated kinase | 2247 | 0.735 | 0.1348 | No |
| 16 | SRF | NA | SRF Entrez, Source | serum response factor (c-fos serum response element-binding transcription factor) | 2257 | 0.733 | 0.1477 | No |
| 17 | PTK2B | NA | PTK2B Entrez, Source | PTK2B protein tyrosine kinase 2 beta | 2398 | 0.703 | 0.1528 | No |
| 18 | SEC24D | NA | SEC24D Entrez, Source | SEC24 related gene family, member D (S. cerevisiae) | 2748 | 0.640 | 0.1452 | No |
| 19 | GUCY1A3 | NA | GUCY1A3 Entrez, Source | guanylate cyclase 1, soluble, alpha 3 | 2778 | 0.634 | 0.1551 | No |
| 20 | MERTK | NA | MERTK Entrez, Source | c-mer proto-oncogene tyrosine kinase | 2956 | 0.603 | 0.1563 | No |
| 21 | HMGCR | NA | HMGCR Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A reductase | 3304 | 0.550 | 0.1472 | No |
| 22 | ACSL3 | NA | ACSL3 Entrez, Source | acyl-CoA synthetase long-chain family member 3 | 3805 | 0.484 | 0.1283 | No |
| 23 | UBE2I | NA | UBE2I Entrez, Source | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 3932 | 0.470 | 0.1299 | No |
| 24 | TNFAIP8 | NA | TNFAIP8 Entrez, Source | tumor necrosis factor, alpha-induced protein 8 | 4315 | 0.420 | 0.1165 | No |
| 25 | CCND1 | NA | CCND1 Entrez, Source | cyclin D1 | 4440 | 0.407 | 0.1170 | No |
| 26 | PTPN21 | NA | PTPN21 Entrez, Source | protein tyrosine phosphatase, non-receptor type 21 | 4479 | 0.402 | 0.1223 | No |
| 27 | UAP1 | NA | UAP1 Entrez, Source | UDP-N-acteylglucosamine pyrophosphorylase 1 | 4758 | 0.377 | 0.1138 | No |
| 28 | TSC22D1 | NA | TSC22D1 Entrez, Source | TSC22 domain family, member 1 | 5195 | 0.332 | 0.0957 | No |
| 29 | GNAI3 | NA | GNAI3 Entrez, Source | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 5414 | 0.311 | 0.0893 | No |
| 30 | PA2G4 | NA | PA2G4 Entrez, Source | proliferation-associated 2G4, 38kDa | 5573 | 0.298 | 0.0860 | No |
| 31 | APPBP2 | NA | APPBP2 Entrez, Source | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 6188 | 0.246 | 0.0565 | No |
| 32 | SMS | NA | SMS Entrez, Source | spermine synthase | 6295 | 0.237 | 0.0550 | No |
| 33 | CDC14B | NA | CDC14B Entrez, Source | CDC14 cell division cycle 14 homolog B (S. cerevisiae) | 6431 | 0.227 | 0.0516 | No |
| 34 | RPS6KA3 | NA | RPS6KA3 Entrez, Source | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 6490 | 0.222 | 0.0525 | No |
| 35 | SRP19 | NA | SRP19 Entrez, Source | signal recognition particle 19kDa | 6858 | 0.191 | 0.0357 | No |
| 36 | TMEM50A | NA | TMEM50A Entrez, Source | transmembrane protein 50A | 6909 | 0.187 | 0.0363 | No |
| 37 | SAT1 | NA | SAT1 Entrez, Source | spermidine/spermine N1-acetyltransferase 1 | 7099 | 0.174 | 0.0290 | No |
| 38 | CDK6 | NA | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 7145 | 0.170 | 0.0296 | No |
| 39 | IQGAP2 | NA | IQGAP2 Entrez, Source | IQ motif containing GTPase activating protein 2 | 7390 | 0.152 | 0.0189 | No |
| 40 | SLC38A2 | NA | SLC38A2 Entrez, Source | solute carrier family 38, member 2 | 7449 | 0.147 | 0.0184 | No |
| 41 | PGM3 | NA | PGM3 Entrez, Source | phosphoglucomutase 3 | 7841 | 0.119 | -0.0011 | No |
| 42 | MYL12A | NA | 7897 | 0.115 | -0.0020 | No | ||
| 43 | AKT1 | NA | AKT1 Entrez, Source | v-akt murine thymoma viral oncogene homolog 1 | 7922 | 0.113 | -0.0013 | No |
| 44 | DNAJB9 | NA | DNAJB9 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 9 | 8229 | 0.091 | -0.0166 | No |
| 45 | DHCR24 | NA | DHCR24 Entrez, Source | 24-dehydrocholesterol reductase | 8233 | 0.091 | -0.0151 | No |
| 46 | SPCS3 | NA | SPCS3 Entrez, Source | signal peptidase complex subunit 3 homolog (S. cerevisiae) | 8510 | 0.071 | -0.0291 | No |
| 47 | KLK3 | NA | KLK3 Entrez, Source | kallikrein 3, (prostate specific antigen) | 8820 | 0.050 | -0.0452 | No |
| 48 | LIFR | NA | LIFR Entrez, Source | leukemia inhibitory factor receptor alpha | 8967 | 0.038 | -0.0526 | No |
| 49 | PIAS1 | NA | PIAS1 Entrez, Source | protein inhibitor of activated STAT, 1 | 9451 | 0.004 | -0.0793 | No |
| 50 | FKBP5 | NA | FKBP5 Entrez, Source | FK506 binding protein 5 | 10207 | -0.031 | -0.1205 | No |
| 51 | LMAN1 | NA | LMAN1 Entrez, Source | lectin, mannose-binding, 1 | 10289 | -0.038 | -0.1243 | No |
| 52 | KLK2 | NA | KLK2 Entrez, Source | kallikrein 2, prostatic | 10335 | -0.040 | -0.1261 | No |
| 53 | NGLY1 | NA | NGLY1 Entrez, Source | N-glycanase 1 | 10533 | -0.050 | -0.1361 | No |
| 54 | GSR | NA | GSR Entrez, Source | glutathione reductase | 10665 | -0.059 | -0.1422 | No |
| 55 | NCOA4 | NA | NCOA4 Entrez, Source | nuclear receptor coactivator 4 | 11050 | -0.081 | -0.1620 | No |
| 56 | SORD | NA | SORD Entrez, Source | sorbitol dehydrogenase | 11068 | -0.082 | -0.1615 | No |
| 57 | ELK4 | NA | ELK4 Entrez, Source | ELK4, ETS-domain protein (SRF accessory protein 1) | 11303 | -0.099 | -0.1726 | No |
| 58 | ARID5B | NA | ARID5B Entrez, Source | AT rich interactive domain 5B (MRF1-like) | 11599 | -0.122 | -0.1867 | No |
| 59 | B4GALT1 | NA | B4GALT1 Entrez, Source | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 11658 | -0.128 | -0.1876 | No |
| 60 | TPD52 | NA | TPD52 Entrez, Source | tumor protein D52 | 11937 | -0.150 | -0.2002 | No |
| 61 | FADS1 | NA | FADS1 Entrez, Source | fatty acid desaturase 1 | 12002 | -0.156 | -0.2009 | No |
| 62 | CENPN | NA | CENPN Entrez, Source | centromere protein N | 12270 | -0.179 | -0.2124 | No |
| 63 | CAMKK2 | NA | CAMKK2 Entrez, Source | calcium/calmodulin-dependent protein kinase kinase 2, beta | 12277 | -0.180 | -0.2095 | No |
| 64 | XRCC5 | NA | XRCC5 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa) | 12283 | -0.181 | -0.2064 | No |
| 65 | BMPR1B | NA | BMPR1B Entrez, Source | bone morphogenetic protein receptor, type IB | 12634 | -0.213 | -0.2219 | No |
| 66 | HOMER2 | NA | HOMER2 Entrez, Source | homer homolog 2 (Drosophila) | 12647 | -0.215 | -0.2187 | No |
| 67 | ELOVL5 | NA | ELOVL5 Entrez, Source | ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 13047 | -0.249 | -0.2362 | No |
| 68 | AKAP12 | NA | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 13511 | -0.293 | -0.2565 | No |
| 69 | ADAMTS1 | NA | ADAMTS1 Entrez, Source | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 13707 | -0.312 | -0.2616 | No |
| 70 | ITGAV | NA | ITGAV Entrez, Source | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 14332 | -0.383 | -0.2891 | No |
| 71 | XRCC6 | NA | XRCC6 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa) | 14534 | -0.410 | -0.2928 | No |
| 72 | SLC26A2 | NA | SLC26A2 Entrez, Source | solute carrier family 26 (sulfate transporter), member 2 | 14688 | -0.429 | -0.2934 | No |
| 73 | ELL2 | NA | ELL2 Entrez, Source | elongation factor, RNA polymerase II, 2 | 14895 | -0.461 | -0.2964 | No |
| 74 | STK39 | NA | STK39 Entrez, Source | serine threonine kinase 39 (STE20/SPS1 homolog, yeast) | 14908 | -0.463 | -0.2886 | No |
| 75 | VAPA | NA | VAPA Entrez, Source | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 15807 | -0.612 | -0.3272 | Yes |
| 76 | SPDEF | NA | SPDEF Entrez, Source | SAM pointed domain containing ets transcription factor | 15885 | -0.631 | -0.3199 | Yes |
| 77 | UBE2J1 | NA | UBE2J1 Entrez, Source | ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast) | 15907 | -0.634 | -0.3095 | Yes |
| 78 | SGK1 | NA | 15983 | -0.652 | -0.3018 | Yes | ||
| 79 | AZGP1 | NA | AZGP1 Entrez, Source | alpha-2-glycoprotein 1, zinc | 16292 | -0.731 | -0.3054 | Yes |
| 80 | HERC3 | NA | HERC3 Entrez, Source | hect domain and RLD 3 | 16340 | -0.745 | -0.2945 | Yes |
| 81 | MAP7 | NA | MAP7 Entrez, Source | microtubule-associated protein 7 | 16361 | -0.751 | -0.2819 | Yes |
| 82 | NKX3-1 | NA | NKX3-1 Entrez, Source | NK3 transcription factor related, locus 1 (Drosophila) | 16875 | -0.915 | -0.2935 | Yes |
| 83 | PMEPA1 | NA | 16965 | -0.954 | -0.2811 | Yes | ||
| 84 | HPGD | NA | HPGD Entrez, Source | hydroxyprostaglandin dehydrogenase 15-(NAD) | 17020 | -0.982 | -0.2661 | Yes |
| 85 | IDI1 | NA | IDI1 Entrez, Source | isopentenyl-diphosphate delta isomerase 1 | 17064 | -0.996 | -0.2503 | Yes |
| 86 | GPD1L | NA | GPD1L Entrez, Source | glycerol-3-phosphate dehydrogenase 1-like | 17113 | -1.020 | -0.2344 | Yes |
| 87 | STEAP4 | NA | STEAP4 Entrez, Source | STEAP family member 4 | 17138 | -1.029 | -0.2169 | Yes |
| 88 | DBI | NA | DBI Entrez, Source | diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) | 17270 | -1.100 | -0.2041 | Yes |
| 89 | ABCC4 | NA | ABCC4 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 17348 | -1.148 | -0.1874 | Yes |
| 90 | HSD17B14 | NA | 17412 | -1.195 | -0.1690 | Yes | ||
| 91 | INSIG1 | NA | INSIG1 Entrez, Source | insulin induced gene 1 | 17447 | -1.215 | -0.1488 | Yes |
| 92 | ALDH1A3 | NA | ALDH1A3 Entrez, Source | aldehyde dehydrogenase 1 family, member A3 | 17486 | -1.245 | -0.1281 | Yes |
| 93 | NDRG1 | NA | NDRG1 Entrez, Source | N-myc downstream regulated gene 1 | 17599 | -1.346 | -0.1098 | Yes |
| 94 | MAF | NA | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 17675 | -1.438 | -0.0877 | Yes |
| 95 | ZBTB10 | NA | ZBTB10 Entrez, Source | zinc finger and BTB domain containing 10 | 17697 | -1.467 | -0.0621 | Yes |
| 96 | ANKH | NA | ANKH Entrez, Source | ankylosis, progressive homolog (mouse) | 17759 | -1.546 | -0.0372 | Yes |
| 97 | RAB4A | NA | RAB4A Entrez, Source | RAB4A, member RAS oncogene family | 17783 | -1.586 | -0.0096 | Yes |
| 98 | SCD | NA | SCD Entrez, Source | stearoyl-CoA desaturase (delta-9-desaturase) | 17828 | -1.686 | 0.0188 | Yes |
