A 6-year-old female patient with a history of epilepsy secondary to extensive alteration of right hemisphere cortical development.
She presented refractory epicardial effusion requiring admission to the Intensive Care Unit for life support and treatment, which included as third-line therapy continuous intravenous infusion of propofol in progressive doses until reaching a rate of 10 mg/h.
Hemodynamic compromise was observed 24 hours after starting treatment, an increase in creatine phosphokinase (CK), metabolic acidosis and high lactacidemia were observed, and after ruling out other causes, the medication was discontinued.
