ACALD	Acetaldehyde + Coenzyme-A + Nicotinamide-adenine-dinucleotide 	<=>	Acetyl-CoA + H + Nicotinamide-adenine-dinucleotide-reduced 	(b0351 or b1241)
ACALDt	Acetaldehyde 	<=>	Acetaldehyde 	s0001
ACKr	Acetate + ATP 	<=>	Acetyl-phosphate + ADP 	(b3115 or b2296 or b1849)
ACONTa	Citrate 	<=>	cis-Aconitate + H2O 	(b0118 or b1276)
ACONTb	cis-Aconitate + H2O 	<=>	Isocitrate 	(b0118 or b1276)
ACt2r	Acetate + H 	<=>	Acetate + H 	
ADK1	AMP + ATP 	<=>	2 ADP 	b0474
AKGDH	2-Oxoglutarate + Coenzyme-A + Nicotinamide-adenine-dinucleotide 	->	CO2 + Nicotinamide-adenine-dinucleotide-reduced + Succinyl-CoA 	( b0116  and  b0726  and  b0727 )
AKGt2r	2-Oxoglutarate + H 	<=>	2-Oxoglutarate + H 	b2587
ALCD2x	Ethanol + Nicotinamide-adenine-dinucleotide 	<=>	Acetaldehyde + H + Nicotinamide-adenine-dinucleotide-reduced 	(b0356 or b1478 or b1241)
ATPM	ATP + H2O 	->	ADP + H + Phosphate 	
ATPS4r	ADP + 4 H + Phosphate 	<=>	ATP + H2O + 3 H 	(((b3736 and b3737 and b3738) and (b3731 and b3732 and b3733 and b3734 and b3735)) or ((b3736 and b3737 and b3738) and (b3731 and b3732 and b3733 and b3734 and b3735) and b3739))
Biomass_Ecoli_core_w_GAM	1.496 3-Phospho-D-glycerate + 3.7478 Acetyl-CoA + 59.81 ATP + 0.361 D-Erythrose-4-phosphate + 0.0709 D-Fructose-6-phosphate + 0.129 Glyceraldehyde-3-phosphate + 0.205 D-Glucose-6-phosphate + 0.2557 L-Glutamine + 4.9414 L-Glutamate + 59.81 H2O + 3.547 Nicotinamide-adenine-dinucleotide + 13.0279 Nicotinamide-adenine-dinucleotide-phosphate-reduced + 1.7867 Oxaloacetate + 0.5191 Phosphoenolpyruvate + 2.8328 Pyruvate + 0.8977 alpha-D-Ribose-5-phosphate 	->	59.81 ADP + 4.1182 2-Oxoglutarate + 3.7478 Coenzyme-A + 59.81 H + 3.547 Nicotinamide-adenine-dinucleotide-reduced + 13.0279 Nicotinamide-adenine-dinucleotide-phosphate + 59.81 Phosphate 	
CO2t	CO2 	<=>	CO2 	s0001
CS	Acetyl-CoA + H2O + Oxaloacetate 	->	Citrate + Coenzyme-A + H 	b0720
CYTBD	2 H + 0.5 O2 + Ubiquinol-8 	->	H2O + 2 H + Ubiquinone-8 	((b0978 and b0979) or (b0733 and b0734))
D_LACt2	H + D-Lactate 	<=>	H + D-Lactate 	( b2975  or  b3603 )
ENO	D-Glycerate-2-phosphate 	<=>	H2O + Phosphoenolpyruvate 	b2779
ETOHt2r	Ethanol + H 	<=>	Ethanol + H 	
EX_ac(e)	Acetate 	->		
EX_acald(e)	Acetaldehyde 	->		
EX_akg(e)	2-Oxoglutarate 	->		
EX_co2(e)	CO2 	<=>		
EX_etoh(e)	Ethanol 	->		
EX_for(e)	Formate 	->		
EX_fru(e)	D-Fructose 	->		
EX_fum(e)	Fumarate 	->		
EX_glc(e)	D-Glucose 	<=>		
EX_gln_L(e)	L-Glutamine 	->		
EX_glu_L(e)	L-Glutamate 	->		
EX_h(e)	H 	<=>		
EX_h2o(e)	H2O 	<=>		
EX_lac_D(e)	D-Lactate 	->		
EX_mal_L(e)	L-Malate 	->		
EX_nh4(e)	Ammonium 	<=>		
EX_o2(e)	O2 	<=>		
EX_pi(e)	Phosphate 	<=>		
EX_pyr(e)	Pyruvate 	->		
EX_succ(e)	Succinate 	->		
FBA	D-Fructose-1-6-bisphosphate 	<=>	Dihydroxyacetone-phosphate + Glyceraldehyde-3-phosphate 	(b2097 or b1773 or b2925)
FBP	D-Fructose-1-6-bisphosphate + H2O 	->	D-Fructose-6-phosphate + Phosphate 	(b3925 or b4232)
FORt2	Formate + H 	->	Formate + H 	(b0904 or b2492)
FORti	Formate 	->	Formate 	(b0904 or b2492)
FRD7	Fumarate + Ubiquinol-8 	->	Ubiquinone-8 + Succinate 	(b4151 and b4152 and b4153 and b4154)
FRUpts2	D-Fructose + Phosphoenolpyruvate 	->	D-Fructose-6-phosphate + Pyruvate 	(b1817 and b1818 and b1819 and b2415 and b2416)
FUM	Fumarate + H2O 	<=>	L-Malate 	( b1612  or  b4122  or  b1611 )
FUMt2_2	Fumarate + 2 H 	->	Fumarate + 2 H 	b3528
G6PDH2r	D-Glucose-6-phosphate + Nicotinamide-adenine-dinucleotide-phosphate 	<=>	6-phospho-D-glucono-1-5-lactone + H + Nicotinamide-adenine-dinucleotide-phosphate-reduced 	b1852
GAPD	Glyceraldehyde-3-phosphate + Nicotinamide-adenine-dinucleotide + Phosphate 	<=>	3-Phospho-D-glyceroyl-phosphate + H + Nicotinamide-adenine-dinucleotide-reduced 	b1779
GLCpts	D-Glucose + Phosphoenolpyruvate 	->	D-Glucose-6-phosphate + Pyruvate 	((b2417 and b1101 and b2415 and b2416) or (b1817 and b1818 and b1819 and b2415 and b2416) or (b2417 and b1621 and b2415 and b2416))
GLNS	ATP + L-Glutamate + Ammonium 	->	ADP + L-Glutamine + H + Phosphate 	(b3870 or b1297)
GLNabc	ATP + L-Glutamine + H2O 	->	ADP + L-Glutamine + H + Phosphate 	(b0811 and b0810 and b0809)
GLUDy	L-Glutamate + H2O + Nicotinamide-adenine-dinucleotide-phosphate 	<=>	2-Oxoglutarate + H + Nicotinamide-adenine-dinucleotide-phosphate-reduced + Ammonium 	b1761
GLUN	L-Glutamine + H2O 	->	L-Glutamate + Ammonium 	(b1812 or b0485 or b1524)
GLUSy	2-Oxoglutarate + L-Glutamine + H + Nicotinamide-adenine-dinucleotide-phosphate-reduced 	->	2 L-Glutamate + Nicotinamide-adenine-dinucleotide-phosphate 	(b3212 and b3213)
GLUt2r	L-Glutamate + H 	<=>	L-Glutamate + H 	b4077
GND	6-Phospho-D-gluconate + Nicotinamide-adenine-dinucleotide-phosphate 	->	CO2 + Nicotinamide-adenine-dinucleotide-phosphate-reduced + D-Ribulose-5-phosphate 	b2029
H2Ot	H2O 	<=>	H2O 	(b0875 or s0001)
ICDHyr	Isocitrate + Nicotinamide-adenine-dinucleotide-phosphate 	<=>	2-Oxoglutarate + CO2 + Nicotinamide-adenine-dinucleotide-phosphate-reduced 	b1136
ICL	Isocitrate 	->	Glyoxylate + Succinate 	b4015
LDH_D	D-Lactate + Nicotinamide-adenine-dinucleotide 	<=>	H + Nicotinamide-adenine-dinucleotide-reduced + Pyruvate 	(b2133 or b1380)
MALS	Acetyl-CoA + Glyoxylate + H2O 	->	Coenzyme-A + H + L-Malate 	( b4014  or  b2976 )
MALt2_2	2 H + L-Malate 	->	2 H + L-Malate 	b3528
MDH	L-Malate + Nicotinamide-adenine-dinucleotide 	<=>	H + Nicotinamide-adenine-dinucleotide-reduced + Oxaloacetate 	b3236
ME1	L-Malate + Nicotinamide-adenine-dinucleotide 	->	CO2 + Nicotinamide-adenine-dinucleotide-reduced + Pyruvate 	b1479
ME2	L-Malate + Nicotinamide-adenine-dinucleotide-phosphate 	->	CO2 + Nicotinamide-adenine-dinucleotide-phosphate-reduced + Pyruvate 	b2463
NADH16	4 H + Nicotinamide-adenine-dinucleotide-reduced + Ubiquinone-8 	->	3 H + Nicotinamide-adenine-dinucleotide + Ubiquinol-8 	(b2276 and b2277 and b2278 and b2279 and b2280 and b2281 and b2282 and b2283 and b2284 and b2285 and b2286 and b2287 and b2288)
NADTRHD	Nicotinamide-adenine-dinucleotide + Nicotinamide-adenine-dinucleotide-phosphate-reduced 	->	Nicotinamide-adenine-dinucleotide-reduced + Nicotinamide-adenine-dinucleotide-phosphate 	(b3962 or (b1602 and b1603))
NH4t	Ammonium 	<=>	Ammonium 	(s0001 or b0451)
O2t	O2 	<=>	O2 	s0001
PDH	Coenzyme-A + Nicotinamide-adenine-dinucleotide + Pyruvate 	->	Acetyl-CoA + CO2 + Nicotinamide-adenine-dinucleotide-reduced 	( b0114  and  b0115  and  b0116 )
PFK	ATP + D-Fructose-6-phosphate 	->	ADP + D-Fructose-1-6-bisphosphate + H 	( b3916  or  b1723 )
PFL	Coenzyme-A + Pyruvate 	->	Acetyl-CoA + Formate 	(((b0902 and b0903) and b2579) or (b0902 and b0903) or (b0902 and b3114) or (b3951 and b3952))
PGI	D-Glucose-6-phosphate 	<=>	D-Fructose-6-phosphate 	b4025
PGK	3-Phospho-D-glycerate + ATP 	<=>	3-Phospho-D-glyceroyl-phosphate + ADP 	b2926
PGL	6-phospho-D-glucono-1-5-lactone + H2O 	->	6-Phospho-D-gluconate + H 	b0767
PGM	D-Glycerate-2-phosphate 	<=>	3-Phospho-D-glycerate 	(b3612 or b4395 or b0755)
PIt2r	H + Phosphate 	<=>	H + Phosphate 	(b2987 or b3493)
PPC	CO2 + H2O + Phosphoenolpyruvate 	->	H + Oxaloacetate + Phosphate 	b3956
PPCK	ATP + Oxaloacetate 	->	ADP + CO2 + Phosphoenolpyruvate 	b3403
PPS	ATP + H2O + Pyruvate 	->	AMP + 2 H + Phosphoenolpyruvate + Phosphate 	b1702
PTAr	Acetyl-CoA + Phosphate 	<=>	Acetyl-phosphate + Coenzyme-A 	(b2297 or b2458)
PYK	ADP + H + Phosphoenolpyruvate 	->	ATP + Pyruvate 	(b1854 or b1676)
PYRt2r	H + Pyruvate 	<=>	H + Pyruvate 	
RPE	D-Ribulose-5-phosphate 	<=>	D-Xylulose-5-phosphate 	(b3386 or b4301)
RPI	alpha-D-Ribose-5-phosphate 	<=>	D-Ribulose-5-phosphate 	( b2914  or  b4090 )
SUCCt2_2	2 H + Succinate 	->	2 H + Succinate 	b3528
SUCCt3	H + Succinate 	->	H + Succinate 	
SUCDi	Ubiquinone-8 + Succinate 	->	Fumarate + Ubiquinol-8 	(b0721 and b0722 and b0723 and b0724)
SUCOAS	ATP + Coenzyme-A + Succinate 	<=>	ADP + Phosphate + Succinyl-CoA 	( b0728  and  b0729 )
TALA	Glyceraldehyde-3-phosphate + Sedoheptulose-7-phosphate 	<=>	D-Erythrose-4-phosphate + D-Fructose-6-phosphate 	(b2464 or b0008)
THD2	2 H + Nicotinamide-adenine-dinucleotide-reduced + Nicotinamide-adenine-dinucleotide-phosphate 	->	2 H + Nicotinamide-adenine-dinucleotide + Nicotinamide-adenine-dinucleotide-phosphate-reduced 	( b1602  and  b1603 )
TKT1	alpha-D-Ribose-5-phosphate + D-Xylulose-5-phosphate 	<=>	Glyceraldehyde-3-phosphate + Sedoheptulose-7-phosphate 	( b2935  or  b2465 )
TKT2	D-Erythrose-4-phosphate + D-Xylulose-5-phosphate 	<=>	D-Fructose-6-phosphate + Glyceraldehyde-3-phosphate 	( b2935  or  b2465 )
TPI	Dihydroxyacetone-phosphate 	<=>	Glyceraldehyde-3-phosphate 	b3919
